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Future Table of Contents: Volume 181 / No. 10 / Nov 15, 2008

IN THIS ISSUE

BRIEF REVIEWS

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

IMMUNOGENETICS

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

IN THIS ISSUE

BRIEF REVIEWS

Mechanisms of Immunity in Hydatid Disease: Implications for Vaccine Development

Wenbao Zhang, Allen G. Ross, and Donald P. McManus

CUTTING EDGE

Experimentally Induced Immune Activation in Natural Hosts of Simian Immunodeficiency Virus Induces Significant Increases in Viral Replication and CD4+ T Cell Depletion

Ivona Pandrea, Thaidra Gaufin, Jason M. Brenchley, Rajeev Gautam, Christopher Monjure, Aarti Gautam, Clint Coleman, Andrew A. Lackner, Ruy M. Ribeiro, Daniel C. Douek, and Cristian Apetrei

Eosinophils Do Not Contribute to Respiratory Syncytial Virus Vaccine-Enhanced Disease

Elaine M. Castilow, Kevin L. Legge, and Steven M. Varga

Helminth Infection Induces IgE in the Absence of - or -Chain Expression

Georgia Perona-Wright, Katja Mohrs, Justin Taylor, Colby Zaph, David Artis, Edward J. Pearce, and Markus Mohrs

FimH Adhesin of Type 1 Fimbriae Is a Novel TLR4 Ligand

Karen L. Mossman, Firoz Mian, Nicole M. Lauzon, Carlton L. Gyles, Brian Lichty, Randy Mackenzie, Navkiran Gill, and Ali A. Ashkar

Programmed Death-1/Programmed Death Ligand 1 Interaction Regulates the Induction and Maintenance of Invariant NKT Cell Anergy

Woo-Sung Chang, Ji-Yeon Kim, Yeon-Jeong Kim, Yun-Sun Kim, Jung-Mi Lee, Miyuki Azuma, Hideo Yagita, and Chang-Yuil Kang

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Aging Impairs IFN Regulatory Factor 7 Up-regulation in Plasmacytoid Dendritic Cells during TLR9 Activation

Heather W. Stout-Delgado, Xin Yang, Wendy E. Walker, Bethany M. Tesar, and Daniel R. Goldstein

Enhanced Early Expansion and Maturation of iNKT Cells Inhibited Autoimmune Pathogenesis in Congenic NOD Mice

Aito Ueno, Jianxiong Wang, Lu Cheng, Jin S. Im, Yan Shi, Steven A. Porcelli, and Yang Yang

Caspase 6 Regulates B Cell Activation and Differentiation into Plasma Cells

Chie Watanabe, Geraldine L. Shu, Timothy S. Zheng, Richard A. Flavell, and Edward A. Clark

The Host Environment Regulates the Function of CD8+ Graft-Versus-Host-Reactive Effector Cells

Ronjon Chakraverty, Barry Flutter, Farnaz Fallah-Arani, Hyeon-Seok Eom, Terry Means, Giovanna Andreola, Sebastian Schwarte, Jennifer Buchli, Pete Cotter, Guiling Zhao, and Megan Sykes

IL-21 Stimulates Human Myeloma Cell Growth through an Autocrine IGF-1 Loop

Emmanuelle Menoret, Sophie Ma|fkga, Geraldine Descamps, Catherine Pellat-Deceunynck, Caroline Fraslon, Melania Cappellano, Philippe Moreau, Regis Bataille, and Martine Amiot

Reversible Blockade of Thymic Output: An Inherent Part of TLR Ligand-Mediated Immune Response

Thomas Demoulins, Ali Abdallah, Nadia Kettaf, Marie-Laurence Baron, Casimiro Gerarduzzi, Dominique Gauchat, Sophie Gratton, and Rafick-Pierre Sekaly

Adaptable TCR Avidity Thresholds for Negative Selection

Milica Stojakovic, Laura I. Salazar-Fontana, Zohreh Tatari-Calderone, Vladimir P. Badovinac, Fabio R. Santori, Damian Kovalovsky, Derek Sant'Angelo, John T. Harty, and Stanislav Vukmanovic

Interaction of Monocytes with NK Cells upon Toll-Like Receptor-Induced Expression of the NKG2D Ligand MICA

Mercedes Kloss, Patrice Decker, Katrin M. Baltz, Tina Baessler, Gundram Jung, Hans-Georg Rammensee, Alexander Steinle, Matthias Krusch, and Helmut R. Salih

Toll-Like Receptor Ligands in the Local Treatment of Established Intracerebral Murine Gliomas

Oliver M. Grauer, Johan W. Molling, Erik Bennink, Liza W. J. Toonen, Roger P. M. Sutmuller, Stefan Nierkens, and Gosse J. Adema

Lipopolysaccharide-Induced Expression of NAD(P)H:Quinone Oxidoreductase 1 and Heme Oxygenase-1 Protects against Excessive Inflammatory Responses in Human Monocytes

Stuart A. Rushworth, David J. MacEwan, and Maria A. O'Connell

The Common -Chain Cytokines IL-2, IL-7, IL-15, and IL-21 Induce the Expression of Programmed Death (PD)-1 and Its Ligands

Audrey L. Kinter, Emily J. Godbout, Jonathan P. McNally, Irini Sereti, Gregg A. Roby, Marie A. O'Shea, and Anthony S. Fauci

Regulatory Roles for NKT Cell Ligands in Environmentally Induced Autoimmunity

Jaya Vas, Jochen Mattner, Stewart Richardson, Rachel Ndonye, John P. Gaughan, Amy Howell, and Marc Monestier

Ion Channels Modulating Mouse Dendritic Cell Functions

Nicole Matzner, Irina M. Zemtsova, Nguyen Thi Xuan, Michael Duszenko, Ekaterina Shumilina, and Florian Lang

IFN- Production by TLR4-Stimulated Innate Immune Cells is Negatively Regulated by GSK3-

Huizhi Wang, Carlos A. Garcia, Kunal Rehani, Caglar Cekic, Pascale Alard, Denis F. Kinane, Thomas Mitchell, and Michael Martin

MHC Variant Peptide-Mediated Anergy of Encephalitogenic T Cells Requires SHP-1

Heather A. Wasserman, Carrie D. Beal, Yan Zhang, Ning Jiang, Cheng Zhu, and Brian D. Evavold

Experimental Antibody Therapy of Liver Metastases Reveals Functional Redundancy between FcRI and FcRIV

Marielle A. Otten, Gerben J. van der Bij, Sjef J. Verbeek, Falk Nimmerjahn, Jeffrey V. Ravetch, Robert H. J. Beelen, Jan G. J. van de Winkel, and Marjolein van Egmond

Targeting Poly(I:C) to the TLR3-Independent Pathway Boosts Effector CD8 T Cell Differentiation through IFN-/

Soo M. Ngoi, Michael G. Tovey, and Anthony T. Vella

Antiviral-Activated Dendritic Cells: A Paracrine-Induced Response State

Antonio V. Borderia, Boris M. Hartmann, Ana Fernandez-Sesma, Thomas M. Moran, and Stuart C. Sealfon

Differential Regulatory Function of Resting and Preactivated Allergen-Specific CD4+CD25+ Regulatory T Cells in Th2-Type Airway Inflammation

Kanako Saito, Mie Torii, Ning Ma, Tomoko Tsuchiya, Linan Wang, Tomohide Hori, Daisuke Nagakubo, Nao Nitta, Shiro Kanegasaki, Kunio Hieshima, Osamu Yoshie, Esteban C. Gabazza, Naoyuki Katayama, Hiroshi Shiku, Kagemasa Kuribayashi, and Takuma Kato

Human CD4+CD25+Foxp3+ Regulatory T Cells Do Not Constitutively Express IL-35

Emilie Bardel, Frederique Larousserie, Pascaline Charlot-Rabiega, Aurore Coulomb-L'Hermine, and Odile Devergne

Transgenic Mice Expressing Dominant-Negative Bright Exhibit Defects in B1 B Cells

Jamee C. Nixon, Scott Ferrell, Cathrine Miner, Athenia L. Oldham, Ute Hochgeschwender, and Carol F. Webb

CD8+CD205+ Splenic Dendritic Cells Are Specialized to Induce Foxp3+ Regulatory T Cells

Sayuri Yamazaki, Diana Dudziak, Gordon F. Heidkamp, Christopher Fiorese, Anthony J. Bonito, Kayo Inaba, Michel C. Nussenzweig, and Ralph M. Steinman

Suppression of Murine Allergic Airway Disease by IL-2:Anti-IL-2 mAb-Induced Regulatory T Cells

Mark S. Wilson, John T. Pesce, Thirumalai R. Ramalingam, Robert W. Thompson, Allen Cheever, and Thomas A. Wynn

Rapid and Selective Expansion of Nonclonotypic T Cells in Regulatory T Cell-Deficient, Foreign Antigen-Specific TCR-Transgenic Scurfy Mice: Antigen-Dependent Expansion and TCR Analysis

Rahul Sharma, Angela Chiao-Ying Ju, John T. Kung, Shu Man Fu, and Shyr-Te Ju

Imatinib Mesylate Inhibits CD4+CD25+ Regulatory T Cell Activity and Enhances Active Immunotherapy against BCR-ABL- Tumors

Nicolas Larmonier, Nona Janikashvili, Collin J. LaCasse, Claire B. Larmonier, Jessica Cantrell, Elaine Situ, Tamara Lundeen, Bernard Bonnotte, and Emmanuel Katsanis

IFN--Dependent Regulatory Circuits in Immune Inflammation Highlighted in Diabetes

Boris Calderon, Anish Suri, Xiaoou O. Pan, Jason C. Mills, and Emil R. Unanue

Targeting CD4 Coreceptor Expression to Postselection Thymocytes Reveals That CD4/CD8 Lineage Choice Is Neither Error-Prone Nor Stochastic

Stanley Adoro, Batu Erman, Sophia D. Sarafova, Francois Van Laethem, Jung-Hyun Park, Lionel Feigenbaum, and Alfred Singer

Dynamin 2 Regulates Granule Exocytosis During NK Cell-Mediated Cytotoxicity

Laura N. Arneson, Colin M. Segovis, Timothy S. Gomez, Renee A. Schoon, Christopher J. Dick, Zhenkun Lou, Daniel D. Billadeau, and Paul J. Leibson

Tetraspanins Regulate ADAM10-Mediated Cleavage of TNF- and Epidermal Growth Factor

Cecile Arduise, Toufik Abache, Lei Li, Martine Billard, Aurelie Chabanon, Andreas Ludwig, Philippe Mauduit, Claude Boucheix, Eric Rubinstein, and Francois Le Naour

Thymocyte-Dendritic Cell Interactions near Sources of CCR7 Ligands in the Thymic Cortex

Ena Ladi, Tanja Schwickert, Tatyana Chtanova, Ying Chen, Paul Herzmark, Xinye Yin, Holly Aaron, Shiao Wei Chan, Martin Lipp, Badrinath Roysam, and Ellen A. Robey

Polysialic Acid, a Glycan with Highly Restricted Expression, Is Found on Human and Murine Leukocytes and Modulates Immune Responses

Penelope M. Drake, Jay K. Nathan, Christina M. Stock, Pamela V. Chang, Marcus O. Muench, Daisuke Nakata, J. Rachel Reader, Phung Gip, Kevin P. K. Golden, Birgit Weinhold, Rita Gerardy-Schahn, Frederic A. TroyII, and Carolyn R. Bertozzi

PI4P5-Kinase I Is Required for Efficient HIV-1 Entry and Infection of T Cells

Marta Barrero-Villar, Jonathan Barroso-Gonzalez, J. Roman Cabrero, Monica Gordon-Alonso, Susana Alvarez-Losada, M. A. Munoz-Fernandez, Francisco Sanchez-Madrid, and Agustin Valenzuela-Fernandez

Neuropeptide Y Is Expressed by Rat Mononuclear Blood Leukocytes and Strongly Down-Regulated during Inflammation

Julia Holler, Anna Zakrzewicz, Andreas Kaufmann, Jochen Wilhelm, Gabriele Fuchs-Moll, Hartmut Dietrich, Winfried Padberg, Jitka Kuncova, Wolfgang Kummer, and Veronika Grau

CD4+ and CD8+ T Cells Exhibit Differential Requirements for CCR7-Mediated Antigen Transport during Influenza Infection

Alex K. Heer, Nicola L. Harris, Manfred Kopf, and Benjamin J. Marsland

Dendritic Cell Differentiation Induced by a Self-Peptide Derived from Apolipoprotein E

Tracey A. Stephens, Enayat Nikoopour, Beverly J. Rider, Matilde Leon-Ponte, Thu A. Chau, Sebastian Mikolajczak, Pratibha Chaturvedi, Edwin Lee-Chan, Richard A. Flavell, S. M. Mansour Haeryfar, Joaquin Madrenas, and Bhagirath Singh

Increased Osteopontin Expression in Dendritic Cells Amplifies IL-17 Production by CD4+ T Cells in Experimental Autoimmune Encephalomyelitis and in Multiple Sclerosis

Gopal Murugaiyan, Akanksha Mittal, and Howard L. Weiner

MOLECULAR AND STRUCTURAL IMMUNOLOGY

A Novel C1q Family Member of Amphioxus Was Revealed to Have a Partial Function of Vertebrate C1q Molecule

Yanhong Yu, Huiqing Huang, Yan Wang, Yingcai Yu, Shaochun Yuan, Shengfeng Huang, Minming Pan, Kaixia Feng, and Anlong Xu

CD45 Down-Regulates Lck-Mediated CD44 Signaling and Modulates Actin Rearrangement in T Cells

Nelson K. Y. Wong, Jacqueline C. Y. Lai, Darlene Birkenhead, Andrey Shaw, and Pauline Johnson

Hyaluronan Induces Cell Death in Activated T Cells through CD44

Brian Ruffell and Pauline Johnson

Negative Regulation of TCR Signaling by Linker for Activation of X Cells via Phosphotyrosine-Dependent and -Independent Mechanisms

Michael J. Shapiro, Chau T. Nguyen, Haig Aghajanian, Weiguo Zhang, and Virginia Smith Shapiro

Processing of an Antigenic Sequence from IgG Constant Domains for Presentation by MHC Class II

Morten Flobakk, Ingunn B. Rasmussen, Elin Lunde, Terje Frigstad, Goril Berntzen, TerjeE. Michaelsen, Bjarne Bogen, and Inger Sandlie

IMMUNOGENETICS

NKG2D-RAE-1 Receptor-Ligand Variation Does Not Account for the NK Cell Defect in Nonobese Diabetic Mice

Lisa M. Maier, Sarah Howlett, Kara Rainbow, Jan Clark, Joanna M. M. Howson, John A. Todd, and Linda S. Wicker

HOST DEFENSE

Induction of TRAIL- and TNF--Dependent Apoptosis in Human Monocyte-Derived Dendritic Cells by Microfilariae of Brugia Malayi

Roshanak Tolouei Semnani, Priyanka Goel Venugopal, Lily Mahapatra, Jason Skinner, Francoise Meylan, Daniel Chien, David Dorward, Damien Chaussabel, Richard M. Siegel, and Thomas B. Nutman

Respiratory Epithelial Cells Convert Inactive Vitamin D to Its Active Form: Potential Effects on Host Defense

Sif Hansdottir, Martha M. Monick, Sara L. Hinde, Nina Lovan, Dwight C. Look, and Gary W. Hunninghake

Aspergillus Conidia Activate the Complement by the Mannan-Binding Lectin C2 Bypass Mechanism

Chantal Dumestre-Perard, Bertrand Lamy, Delphine Aldebert, Catherine Lemaire-Vieille, Renee Grillot, Jean-Paul Brion, Jean Gagnon, and Jean-Yves Cesbron

Histoplasma capsulatum Cyclophilin A Mediates Attachment to Dendritic Cell VLA-5

Francisco J. Gomez, Robyn Pilcher-Roberts, Arash Alborzi, and Simon L. Newman

IL-15 Links TLR2/1-Induced Macrophage Differentiation to the Vitamin D-Dependent Antimicrobial Pathway

Stephan R. Krutzik, Martin Hewison, Philip T. Liu, Juan Antonio Robles, Steffen Stenger, John S. Adams, and Robert L. Modlin

A Novel Role for Neutrophils As Critical Activators of NK Cells

Roman Sporri, Nicole Joller, Hubert Hilbi, and Annette Oxenius

TNF- Is a Positive Regulatory Factor for Human V2V2 T Cells

Haishan Li, Kun Luo, and C. David Pauza

Nod2-Dependent Th2 Polarization of Antigen-Specific Immunity

Joao Gamelas Magalhaes, Jorg H. Fritz, Lionel Le Bourhis, Gernot Sellge, Leonardo H. Travassos, Thirumahal Selvanantham, Stephen E. Girardin, Jennifer L. Gommerman, and Dana J. Philpott

Species-Specific Interaction of Streptococcus pneumoniae with Human Complement Factor H

Ling Lu, Zhuo Ma, T. Sakari Jokiranta, Adeline R. Whitney, Frank R. DeLeo, and Jing-Ren Zhang

Role of Human CD36 in Bacterial Recognition, Phagocytosis, and Pathogen-Induced JNK-Mediated Signaling

Irina N. Baranova, Roger Kurlander, Alexander V. Bocharov, Tatyana G. Vishnyakova, Zhigang Chen, Alan T. Remaley, Gyorgy Csako, Amy P. Patterson, and Thomas L. Eggerman

NOD2-Deficient Mice Have Impaired Resistance to Mycobacterium tuberculosis Infection through Defective Innate and Adaptive Immunity

Maziar Divangahi, Serge Mostowy, Francois Coulombe, Robert Kozak, Loïc Guillot, Frederic Veyrier, Koichi S. Kobayashi, Richard A. Flavell, Philippe Gros, and Marcel A. Behr

The ESX-5 Secretion System of Mycobacterium marinum Modulates the Macrophage Response

Abdallah M. Abdallah, Nigel D. L. Savage, Maaike van Zon, Louis Wilson, Christina M. J .E. Vandenbroucke-Grauls, Nicole N. van der Wel, Tom H. M. Ottenhoff, and Wilbert Bitter

INFLAMMATION

IL-10 and TGF- Redundantly Protect against Severe Liver Injury and Mortality during Acute Schistosomiasis

De'Broski R. Herbert, Tatyana Orekov, Charles Perkins, and Fred D. Finkelman

Chlamydia pneumoniae-Induced Foam Cell Formation Requires MyD88-Dependent and -Independent Signaling and Is Reciprocally Modulated by Liver X Receptor Activation

Shuang Chen, Rosalinda Sorrentino, Kenichi Shimada, Yonca Bulut, Terence M. Doherty, Timothy R. Crother, and Moshe Arditi

Macrophage Antigen Complex-1 Mediates Reactive Microgliosis and Progressive Dopaminergic Neurodegeneration in the MPTP Model of Parkinson's Disease

Xiaoming Hu, Dan Zhang, Hao Pang, W. Michael Caudle, Yachen Li, Huiming Gao, Yuxin Liu, Li Qian, Belinda Wilson, Donato A. Di Monte, Syed F. Ali, Jing Zhang, Michelle L. Block, and Jau-Shyong Hong

Transgenic Expression of Cyclooxygenase-2 in Hepatocytes Accelerates Endotoxin-Induced Acute Liver Failure

Tong Wu, Guiying Li, Kyu Lim, Marie C. DeFrances, Chandrashekhar R. Gandhi, and Chang Han

Phenotype Switching by Inflammation-Inducing Polarized Th17 Cells, but Not by Th1 Cells

Guangpu Shi, Catherine A. Cox, Barbara P. Vistica, Cuiyan Tan, Eric F. Wawrousek, and Igal Gery

CD4+CD25+ Foxp3+ Regulatory T Cells Protect Against T Cell-Mediated Fulmilant Hepatitis in a TGF--Dependent Manner in Mice

Hua-Xing Wei, Ya-Hui Chuang, Bofeng Li, Haiming Wei, Rui Sun, Yuki Moritoki, Eric M. Gershwin, Zhe-Xiong Lian, and Zhigang Tian

Dendritic Cells Genetically Engineered to Express IL-10 Induce Long-Lasting Antigen-Specific Tolerance in Experimental Asthma

Emmanuelle Henry, Christophe J. Desmet, Virginie Garze, Laurence Fievez, Denis Bedoret, Carlo Heirman, Pedro Faisca, Fabrice J. Jaspar, Philippe Gosset, Alain P.A. Jacquet, Daniel Desmecht, Kris Thielemans, Pierre Lekeux, Muriel Moser, and Fabrice Bureau

Mechanisms of Oncostatin M-Induced Pulmonary Inflammation and Fibrosis

Afsaneh Mozaffarian, Avery W. Brewer, Esther S. Trueblood, Irina G. Luzina, Nevins W. Todd, Sergei P. Atamas, and Heather A. Arnett

Fibrillar Amyloid- Peptides Activate Microglia Via TLR2: Implications for Alzheimer's Disease

Malabendu Jana, Carlos A. Palencia, and Kalipada Pahan

TGF-1 Attenuates Mediator Release and De Novo Kit Expression by Human Skin Mast Cells through a Smad-Dependent Pathway

Wei Zhao, Gregorio Gomez, Shao-Hua Yu, John J. Ryan, and Lawrence B. Schwartz

TLR/MyD88 and Liver X Receptor Signaling Pathways Reciprocally Control Chlamydia pneumoniae-Induced Acceleration of Atherosclerosis

Yoshikazu Naiki, Rosalinda Sorrentino, Michelle H. Wong, Kathrin S. Michelsen, Kenichi Shimada, Shuang Chen, Atilla Yilmaz, Anatoly Slepenkin, Nicolas W. J. Schroder, Timothy R. Crother, Yonca Bulut, Terence M. Doherty, Michelle Bradley, Zory Shaposhnik, Ellena M. Peterson, Peter Tontonoz, Prediman K. Shah, and Moshe Arditi

Prostaglandin E2 Inhibits Eosinophil Trafficking through EP2 Receptors

Eva M. Sturm, Petra Schratl, Rufina Schuligoi, Viktoria Konya, Gunter J. Sturm, Irmgard Th. Lippe, Bernhard A. Peskar, and Akos Heinemann

NF-B-Driven STAT2 and CCL2 Expression in Astrocytes in Response to Brain Injury

Reza Khorooshi, Alicia A. Babcock, and Trevor Owens

Pleural Mesothelial Cells Express Both BLT2 and PPAR and Mount an Integrated Response to Pleural LTB4

Elisabetta Pace, Maria Ferraro, Christopher H. Mody, Mario R. Melis, Valeria Scafidi, Anna Bonanno, Mirella Profita, Antonino Giarratano, and Mark Gjomarkaj

The Effect of the JNK Inhibitor, JIP, on Human T Lymphocyte Proliferation and Cytokine Production

Michelle Melino, Charles S. Hii, Shaun R. McColl, and Antonio Ferrante

A New Mechanism for Inhalational Priming: IL-4 Bypasses Innate Immune Signals

Anna M. Dittrich, Hui-Chen Chen, Lan Xu, Patricia Ranney, Sean Connolly, Timur Yarovinsky, and H. Kim Bottomly

Dual Regulatory Roles of PI3K in IFN Signaling

Surinder Kaur, Antonella Sassano, Ajith M. Joseph, Beata Majchrzak-Kita, Elizabeth A. Eklund, Amit Verma, Saskia M. Brachmann, Eleanor N. Fish, and Leonidas C. Platanias

Active Caspase-1-Mediated Secretion of Retinoic Acid Inducible Gene-I

Min-Jung Kim and Joo-Yeon Yoo

Induction of Scavenger Receptor Class B Type I Is Critical for Simvastatin Enhancement of High-Density Lipoprotein-Induced Anti-Inflammatory Actions in Endothelial Cells

Takao Kimura, Chihiro Mogi, Hideaki Tomura, Atsushi Kuwabara, Doon-Soon Im, Koichi Sato, Hitoshi Kurose, Masami Murakami, and Fumikazu Okajima

Oncostatin M-Induced and Constitutive Activation of the JAK2/STAT5/CIS Pathway Suppresses CCL1, but not CCL7 and CCL8, Chemokine Expression

Christoph Hintzen, Claude Haan, Jan P. Tuckermann, Peter C. Heinrich, and Heike M. Hermanns

CLINICAL IMMUNOLOGY

The Effector T Cells of Diabetic Subjects Are Resistant to Regulation via CD4+FOXP3+ Regulatory T Cells

Anya Schneider, Mary Rieck, Srinath Sanda, Catherine Pihoker, Carla Greenbaum, and Jane H. Buckner

Measles Virus Infection in Adults Induces Production of IL-10 and Is Associated with Increased CD4+CD25+ Regulatory T Cells

Xue-lian Yu, Yu-ming Cheng, Bi-sheng Shi, Fang-xing Qian, Feng-bin Wang, Xi-nian Liu, Hai-ying Yang, Qin-nian Xu, Tang-kai Qi, Li-jun Zha, Zheng-hong Yuan, and Reena Ghildyal

Sunlight Triggers Cutaneous Lupus through a CSF-1-dependent Mechanism in MRL-Faslpr Mice

Julia Menke, Mei-Yu Hsu, Katelyn T. Byrne, Julie A. Lucas, Whitney A. Rabacal, Byron P. Croker, Xiao-Hua Zong, E. Richard Stanley, and Vicki R. Kelley

Breaking of CD8+ T Cell Tolerance through In Vivo Ligation of CD40 Results in Inhibition of Chronic Graft-versus-Host Disease (GVHD) and Complete Donor Cell Engraftment

Juyang Kim, Keunhee Park, Hyun J. Kim, Jiyoung Kim, Hyun-A Kim, Daehee Jung, Hye J. Kim, Hye-Jeong Choi, Suck-Young Choi, Kwang W. Seo, Hong R. Cho, and Byungsuk Kwon

Intestinal Macrophage/Epithelial Cell-Derived CCL11/Eotaxin-1 Mediates Eosinophil Recruitment and Function in Pediatric Ulcerative Colitis

Richard Ahrens, Amanda Beichler, Luqman Seidu, Carine Blanchard, Rebecca Carey, Elizabeth Forbes, Maria Lampinen, Tara Wilson, Elizabeth Cohen, Keith Stringer, Edgar Ballard, Ariel Munitz, Huan Xu, Nancy Lee, James J. Lee, Marc E. Rothenberg, Lee Denson, and Simon P. Hogan

Telomerase-Based Pharmacologic Enhancement of Antiviral Function of Human CD8+ T Lymphocytes

Steven Russell Fauce, Beth D. Jamieson, Allison C. Chin, Ronald T. Mitsuyasu, Stan T. Parish, Hwee L. Ng, Christina M. Ramirez Kitchen, Otto O. Yang, Calvin B. Harley, and Rita B. Effros

Promiscuous Interaction between Gold-Specific T Cells and APCs in Gold Allergy

Hideo Hashizume, Naohiro Seo, Taisuke Ito, Masahiro Takigawa, and Hiroaki Yagi

Multiple Glycines in TCR -Chains Determine Clonally Diverse Nature of Human T Cell Memory to Influenza A Virus

Yuri N. Naumov, Elena N. Naumova, Maryam B. Yassai, Kalyani Kota, Raymond M. Welsh, and Liisa K. Selin

Low Expression of the IL-23/Th17 Pathway in Atopic Dermatitis Compared to Psoriasis

Emma Guttman-Yassky, Michelle A. Lowes, Judilyn Fuentes-Duculan, Lisa C. Zaba, Irma Cardinale, Kristine E. Nograles, Artemis Khatcherian, Inna Novitskaya, John A. Carucci, Reuven Bergman, and James G. Krueger