IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2009 183: 6857-6858; doi:10.4049/jimmunol.0990100 [Full Text] [PDF] ImmunoCast  

LETTERS TO THE EDITOR:

Comment on "TLR9-Dependent Activation of Dendritic Cells by DNA from Leishmania major Favors Th1 Cell Development and the Resolution of Lesions"

Christian Bogdan and Ulrike Schleicher
J Immunol 2009 183: 6859; doi:10.4049/jimmunol.0990096 [Full Text] [PDF]  

Response to Comment on "TLR9-Dependent Activation of Dendritic Cells by DNA from Leishmania major Favors Th1 Cell Development and the Resolution of Lesions"

Noëlle Doyen
J Immunol 2009 183: 6859; doi:10.4049/jimmunol.0990097 [Full Text] [PDF]  

PILLARS OF IMMUNOLOGY:

A Crucial Door to the Mast Cell Mystery Knocked In

Toshiaki Kawakami
J Immunol 2009 183: 6861-6862; doi:10.4049/jimmunol.0990101 [Full Text] [PDF] [Original Pillars Article]  

Pillars Article: Fate of Bone Marrow-Derived Cultured Mast Cells After Intracutaneous, Intraperitoneal, And Intravenous Transfer Into Genetically Mast Cell-Deficient W/Wv Mice. Evidence That Cultured Mast Cells Can Give Rise To Both Connective Tissue Type And Mucosal Mast Cells. The Journal of Experimental Medicine. 1985. 162: 1025–1043

Toru Nakano, Takashi Sonoda, Chieko Hayashi, Atsushi Yamatodani, Yoshio Kanayama, Tei-Ichi Yamamura, Hidekazu Asai, Takeshi Yonezawa, Yukihiko Kitamura, and Stephen J. Galli
J Immunol 2009 183: 6863-6881 [PDF]  

BRIEF REVIEWS:

What Role Does the Route of Immunization Play in the Generation of Protective Immunity against Mucosal Pathogens?

Igor M. Belyakov and Jeffrey D. Ahlers
J Immunol 2009 183: 6883-6892; doi:10.4049/jimmunol.0901466 [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: Requirement of MARCH-I-Mediated MHC II Ubiquitination for the Maintenance of Conventional Dendritic Cells

Mari Ohmura-Hoshino, Yohei Matsuki, Mari Mito-Yoshida, Eiji Goto, Masami Aoki-Kawasumi, Manabu Nakayama, Osamu Ohara, and Satoshi Ishido
J Immunol 2009 183: 6893-6897. Published online November 16, 2009; doi:10.4049/jimmunol.0902178 [Abstract] [Full Text] [PDF] Data Supplement  

Cutting Edge: Memory CD8 T Cell Compartment Grows in Size with Immunological Experience but Nevertheless Can Lose Function

Katharina M. Huster, Christian Stemberger, Georg Gasteiger, Wolfgang Kastenmüller, Ingo Drexler, and Dirk H. Busch
J Immunol 2009 183: 6898-6902. Published online November 4, 2009; doi:10.4049/jimmunol.0902454 [Abstract] [Full Text] [PDF] Data Supplement  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Peroxisome Proliferator-Activated Receptor Ligands Enhance Human B Cell Antibody Production and Differentiation

Tatiana M. Garcia-Bates, Carolyn J. Baglole, Matthew P. Bernard, Thomas I. Murant, Patricia J. Simpson-Haidaris, and Richard P. Phipps
J Immunol 2009 183: 6903-6912. Published online November 13, 2009; doi:10.4049/jimmunol.0900324 [Abstract] [Full Text] [PDF]  

Impaired NK Cytolytic Activity and Enhanced Tumor Growth in NK Lytic-Associated Molecule-Deficient Mice

Richard G. Hoover, Gail Gullickson, and Jacki Kornbluth
J Immunol 2009 183: 6913-6921. Published online November 13, 2009; doi:10.4049/jimmunol.0901679 [Abstract] [Full Text] [PDF]  

NOD2 Ligation Subverts IFN- Production by Liver Plasmacytoid Dendritic Cells and Inhibits Their T Cell Allostimulatory Activity via B7-H1 Up-Regulation

Antonino Castellaneta, Tina L. Sumpter, Lieping Chen, Daisuke Tokita, and Angus W. Thomson
J Immunol 2009 183: 6922-6932. Published online November 4, 2009; doi:10.4049/jimmunol.0900582 [Abstract] [Full Text] [PDF] Data Supplement  

Intranasal Immunization Promotes Th17 Immune Responses

Beata M. Zygmunt, Faiza Rharbaoui, Lothar Groebe, and Carlos A. Guzman
J Immunol 2009 183: 6933-6938. Published online November 4, 2009; doi:10.4049/jimmunol.0901144 [Abstract] [Full Text] [PDF] Data Supplement  

Chimeric NKG2D Expressing T Cells Eliminate Immunosuppression and Activate Immunity within the Ovarian Tumor Microenvironment

Amorette Barber, Agnieszka Rynda, and Charles L. Sentman
J Immunol 2009 183: 6939-6947. Published online November 13, 2009; doi:10.4049/jimmunol.0902000 [Abstract] [Full Text] [PDF]  

RREB-1 Is a Transcriptional Repressor of HLA-G

Sébastien Flajollet, Isabelle Poras, Edgardo D. Carosella, and Philippe Moreau
J Immunol 2009 183: 6948-6959. Published online November 4, 2009; doi:10.4049/jimmunol.0902053 [Abstract] [Full Text] [PDF] Data Supplement  

TLR2 Promotes Th2/Th17 Responses via TLR4 and TLR7/8 by Abrogating the Type I IFN Amplification Loop

Mark H. Wenink, Kim C. M. Santegoets, Jacobus C. A. Broen, Lenny van Bon, Shahla Abdollahi-Roodsaz, Calin Popa, Richard Huijbens, Thijs Remijn, Erik Lubberts, Piet L. C. M. van Riel, Wim B. van den Berg, and Timothy R. D. J. Radstake
J Immunol 2009 183: 6960-6970. Published online November 13, 2009; doi:10.4049/jimmunol.0900713 [Abstract] [Full Text] [PDF]  

Innate Immune CD11b⁺Gr-1⁺ Cells, Suppressor Cells, Affect the Immune Response during Theiler’s Virus-Induced Demyelinating Disease

Jenna L. Bowen and Julie K. Olson
J Immunol 2009 183: 6971-6980. Published online November 4, 2009; doi:10.4049/jimmunol.0902193 [Abstract] [Full Text] [PDF] Data Supplement  

Prostacyclin Inhibits IFN--Stimulated Cytokine Expression by Reduced Recruitment of CBP/p300 to STAT1 in a SOCS-1-Independent Manner

Derek Strassheim, Suzzette R. Riddle, Danielle L. Burke, Mark W. Geraci, and Kurt R. Stenmark
J Immunol 2009 183: 6981-6988. Published online November 13, 2009; doi:10.4049/jimmunol.0901045 [Abstract] [Full Text] [PDF]  

Role of Double-Stranded RNA Pattern Recognition Receptors in Rhinovirus-Induced Airway Epithelial Cell Responses

Qiong Wang, Deepti R. Nagarkar, Emily R. Bowman, Dina Schneider, Babina Gosangi, Jing Lei, Ying Zhao, Christina L. McHenry, Richai V. Burgens, David J. Miller, Umadevi Sajjan, and Marc B. Hershenson
J Immunol 2009 183: 6989-6997. Published online November 4, 2009; doi:10.4049/jimmunol.0901386 [Abstract] [Full Text] [PDF]  

Estrogen Regulates Transcription Factors STAT-1 and NF-B to Promote Inducible Nitric Oxide Synthase and Inflammatory Responses

Rujuan Dai, Rebecca A. Phillips, Ebru Karpuzoglu, Deena Khan, and S. Ansar Ahmed
J Immunol 2009 183: 6998-7005. Published online November 4, 2009; doi:10.4049/jimmunol.0901737 [Abstract] [Full Text] [PDF] Data Supplement  

IL-9 Regulates Pathology during Primary and Memory Responses to Respiratory Syncytial Virus Infection

Jonathan S. Dodd, Eda Lum, John Goulding, Roshell Muir, Jacques Van Snick, and Peter J. M. Openshaw
J Immunol 2009 183: 7006-7013. Published online November 13, 2009; doi:10.4049/jimmunol.0900085 [Abstract] [Full Text] [PDF] Data Supplement  

Limited Role of CD4⁺Foxp3⁺ Regulatory T Cells in the Control of Experimental Cerebral Malaria

Christiane Steeg, Guido Adler, Tim Sparwasser, Bernhard Fleischer, and Thomas Jacobs
J Immunol 2009 183: 7014-7022. Published online November 4, 2009; doi:10.4049/jimmunol.0901422 [Abstract] [Full Text] [PDF]  

Systemic Increase in the Ratio between Foxp3⁺ and IL-17-Producing CD4⁺ T Cells in Healthy Pregnancy but Not in Preeclampsia

Brigitte Santner-Nanan, Michael John Peek, Roma Khanam, Luise Richarts, Erhua Zhu, Barbara Fazekas de St Groth, and Ralph Nanan
J Immunol 2009 183: 7023-7030. Published online November 13, 2009; doi:10.4049/jimmunol.0901154 [Abstract] [Full Text] [PDF]  

Female and Male Sex Hormones Differentially Regulate Expression of Ifi202, an Interferon-Inducible Lupus Susceptibility Gene within the Nba2 Interval

Ravichandran Panchanathan, Hui Shen, Melanie Gubbels Bupp, Karen A. Gould, and Divaker Choubey
J Immunol 2009 183: 7031-7038. Published online November 4, 2009; doi:10.4049/jimmunol.0802665 [Abstract] [Full Text] [PDF]  

Absence of the Transcriptional Repressor Blimp-1 in Hematopoietic Lineages Reveals Its Role in Dendritic Cell Homeostatic Development and Function

Yueh-Hsuan Chan, Ming-Feng Chiang, Yueh-Chiao Tsai, Shin-Tang Su, Ming-Hsu Chen, Mau-Sheng Hou, and Kuo-I Lin
J Immunol 2009 183: 7039-7046. Published online November 13, 2009; doi:10.4049/jimmunol.0901543 [Abstract] [Full Text] [PDF] Data Supplement  

SOCS3 in T and NKT Cells Negatively Regulates Cytokine Production and Ameliorates ConA-Induced Hepatitis

Mako Nakaya, Masayuki Hashimoto, Ryusuke Nakagawa, Yu Wakabayashi, Takuma Ishizaki, Ichiro Takada, Kyoko Komai, Hiroki Yoshida, and Akihiko Yoshimura
J Immunol 2009 183: 7047-7053. Published online November 13, 2009; doi:10.4049/jimmunol.0900547 [Abstract] [Full Text] [PDF]  

Dendritic Cells Secrete the Immunosuppressive HLA-G Molecule upon CTLA4-Ig Treatment: Implication in Human Renal Transplant Acceptance

Rajia Bahri, Abderrahim Naji, Catherine Menier, Bernard Charpentier, Edgardo D. Carosella, Nathalie Rouas-Freiss, and Antoine Durrbach
J Immunol 2009 183: 7054-7062. Published online November 13, 2009; doi:10.4049/jimmunol.0803054 [Abstract] [Full Text] [PDF]  

Interplay between Chromatin Remodeling and Epigenetic Changes during Lineage-Specific Commitment to Granzyme B Expression

Torsten Juelich, Elissa Sutcliffe, Alice Denton, Yiqing He, Peter C. Doherty, Christopher Parish, Steven J. Turner, David Tremethick, and Sudha Rao
J Immunol 2009 183: 7063-7072. Published online November 13, 2009; doi:10.4049/jimmunol.0901522 [Abstract] [Full Text] [PDF] Data Supplement  

Mast Cell Differentiation and Activation Is Closely Linked to Expression of Genes Coding for the Serglycin Proteoglycan Core Protein and a Distinct Set of Chondroitin Sulfate and Heparin Sulfotransferases

Annette Duelli, Elin Rönnberg, Ida Waern, Maria Ringvall, Svein O. Kolset, and Gunnar Pejler
J Immunol 2009 183: 7073-7083. Published online November 13, 2009; doi:10.4049/jimmunol.0900309 [Abstract] [Full Text] [PDF]  

Sex Steroid Ablation Enhances Hematopoietic Recovery following Cytotoxic Antineoplastic Therapy in Aged Mice

Jarrod A. Dudakov, Gabrielle L. Goldberg, Jessica J. Reiseger, Katerina Vlahos, Ann P. Chidgey, and Richard L. Boyd
J Immunol 2009 183: 7084-7094. Published online November 4, 2009; doi:10.4049/jimmunol.0900196 [Abstract] [Full Text] [PDF]  

Dendritic Cells Matured by Inflammation Induce CD86-Dependent Priming of Naive CD8⁺ T Cells in the Absence of Their Cognate Peptide Antigen

Asher Maroof, Lynette Beattie, Alun Kirby, Mark Coles, and Paul M. Kaye
J Immunol 2009 183: 7095-7103. Published online November 16, 2009; doi:10.4049/jimmunol.0901330 [Abstract] [Full Text] [PDF] Data Supplement  

Apoptotic Dendritic Cells Induce Tolerance in Mice through Suppression of Dendritic Cell Maturation and Induction of Antigen-Specific Regulatory T Cells

Rahul Kushwah, Jordan R. Oliver, Jinyi Zhang, Katherine A. Siminovitch, and Jim Hu
J Immunol 2009 183: 7104-7118. Published online November 16, 2009; doi:10.4049/jimmunol.0900824 [Abstract] [Full Text] [PDF] Data Supplement  

Deciphering the Immune Function and Regulation by a TLR of the Cytokine EMAPII in the Lesioned Central Nervous System Using a Leech Model

David Schikorski, Virginie Cuvillier-Hot, Céline Boidin-Wichlacz, Christian Slomianny, Michel Salzet, and Aurélie Tasiemski
J Immunol 2009 183: 7119-7128. Published online November 16, 2009; doi:10.4049/jimmunol.0900538 [Abstract] [Full Text] [PDF]  

Dominant Expression of the Inhibitory FcRIIB Prevents Antigen Presentation by Murine Plasmacytoid Dendritic Cells

Marcella Flores, Dharmesh D. Desai, Matthew Downie, Bitao Liang, Michael P. Reilly, Steven E. McKenzie, and Raphael Clynes
J Immunol 2009 183: 7129-7139. Published online November 16, 2009; doi:10.4049/jimmunol.0901169 [Abstract] [Full Text] [PDF]  

Plasmacytoid Dendritic Cells Regulate Autoreactive B Cell Activation via Soluble Factors and in a Cell-to-Cell Contact Manner

Chuanlin Ding, Yihua Cai, Jose Marroquin, Suzanne T. Ildstad, and Jun Yan
J Immunol 2009 183: 7140-7149. Published online November 4, 2009; doi:10.4049/jimmunol.0901175 [Abstract] [Full Text] [PDF]  

Neonatal Innate TLR-Mediated Responses Are Distinct from Those of Adults

Tobias R. Kollmann, Juliet Crabtree, Annie Rein-Weston, Darren Blimkie, Francis Thommai, Xiu Yu Wang, Pascal M. Lavoie, Jeff Furlong, Edgardo S. Fortuno, III, Adeline M. Hajjar, Natalie R. Hawkins, Steven G. Self, and Christopher B. Wilson
J Immunol 2009 183: 7150-7160. Published online November 16, 2009; doi:10.4049/jimmunol.0901481 [Abstract] [Full Text] [PDF] Data Supplement  

Tc17 CD8 T Cells: Functional Plasticity and Subset Diversity

Hung-Rong Yen, Timothy J. Harris, Satoshi Wada, Joseph F. Grosso, Derese Getnet, Monica V. Goldberg, Kai-Li Liang, Tullia C. Bruno, Kristin J. Pyle, Siaw-Li Chan, Robert A. Anders, Cornelia L. Trimble, Adam J. Adler, Tzou-Yien Lin, Drew M. Pardoll, Ching-Tai Huang, and Charles G. Drake
J Immunol 2009 183: 7161-7168. Published online November 16, 2009; doi:10.4049/jimmunol.0900368 [Abstract] [Full Text] [PDF]  

Th1, Th17, and Th9 Effector Cells Induce Experimental Autoimmune Encephalomyelitis with Different Pathological Phenotypes

Anneli Jäger, Valérie Dardalhon, Raymond A. Sobel, Estelle Bettelli, and Vijay K. Kuchroo
J Immunol 2009 183: 7169-7177. Published online November 4, 2009; doi:10.4049/jimmunol.0901906 [Abstract] [Full Text] [PDF]  

Recruitment of Sprouty1 to Immune Synapse Regulates T Cell Receptor Signaling

Jun Sung Lee, Ji Eun Lee, Yu Mi Oh, Jong Bae Park, Heonsik Choi, Chung Yeon Choi, In-Hoo Kim, Seung Hoon Lee, and Kyungho Choi
J Immunol 2009 183: 7178-7186. Published online November 13, 2009; doi:10.4049/jimmunol.0803799 [Abstract] [Full Text] [PDF]  

Processing in the Endoplasmic Reticulum Generates an Epitope on the Insulin A Chain that Stimulates Diabetogenic CD8 T Cell Responses

Helen Brosi, Michael Reiser, Tarvo Rajasalu, Andreas Spyrantis, Franz Oswald, Bernhard Otto Boehm, and Reinhold Schirmbeck
J Immunol 2009 183: 7187-7195. Published online November 4, 2009; doi:10.4049/jimmunol.0901573 [Abstract] [Full Text] [PDF]  

Ineffective Vaccination against Solid Tumors Can Be Enhanced by Hematopoietic Cell Transplantation

Alexander Filatenkov, Antonia M. S. Müller, William Wei-Lin Tseng, Sussan Dejbakhsh-Jones, Daniel Winer, Richard Luong, Judith A. Shizuru, Edgar G. Engleman, and Samuel Strober
J Immunol 2009 183: 7196-7203. Published online November 4, 2009; doi:10.4049/jimmunol.0900159 [Abstract] [Full Text] [PDF]  

P-Selectin Glycoprotein Ligand-1 Negatively Regulates T-Cell Immune Responses

Masanori Matsumoto, Masayuki Miyasaka, and Takako Hirata
J Immunol 2009 183: 7204-7211. Published online November 4, 2009; doi:10.4049/jimmunol.0902173 [Abstract] [Full Text] [PDF] Data Supplement  

Dynamic Regulation of Notch 1 and Notch 2 Surface Expression during T Cell Development and Activation Revealed by Novel Monoclonal Antibodies

Emma Fiorini, Estelle Merck, Anne Wilson, Isabel Ferrero, Wei Jiang, Ute Koch, Floriane Auderset, Elisa Laurenti, Fabienne Tacchini-Cottier, Michel Pierres, Freddy Radtke, Sanjiv A. Luther, and H. Robson MacDonald
J Immunol 2009 183: 7212-7222. Published online November 13, 2009; doi:10.4049/jimmunol.0902432 [Abstract] [Full Text] [PDF]  

Inhibition of RANK Expression and Osteoclastogenesis by TLRs and IFN- in Human Osteoclast Precursors

Jong-Dae Ji, Kyung-Hyun Park-Min, Zenxin Shen, Roberto J. Fajardo, Steven R. Goldring, Kevin P. McHugh, and Lionel B. Ivashkiv
J Immunol 2009 183: 7223-7233. Published online November 4, 2009; doi:10.4049/jimmunol.0900072 [Abstract] [Full Text] [PDF] Data Supplement  

SHP-2 Expression Negatively Regulates NK Cell Function

Amanda K. Purdy and Kerry S. Campbell
J Immunol 2009 183: 7234-7243. Published online November 13, 2009; doi:10.4049/jimmunol.0900088 [Abstract] [Full Text] [PDF]  

MHC Drives TCR Repertoire Shaping, but not Maturation, in Recent Thymic Emigrants

Evan G. Houston, Jr. and Pamela J. Fink
J Immunol 2009 183: 7244-7249. Published online November 13, 2009; doi:10.4049/jimmunol.0902313 [Abstract] [Full Text] [PDF]  

Ectopic T-bet Expression Licenses Dendritic Cells for IL-12-Independent Priming of Type 1 T Cells In Vitro

Michael W. Lipscomb, Lu Chen, Jennifer L. Taylor, Christina Goldbach, Simon C. Watkins, Pawel Kalinski, Lisa H. Butterfield, Amy K. Wesa, and Walter J. Storkus
J Immunol 2009 183: 7250-7258. Published online November 13, 2009; doi:10.4049/jimmunol.0901477 [Abstract] [Full Text] [PDF] Data Supplement  

SLAT/Def6 Plays a Critical Role in the Development of Th17 Cell-Mediated Experimental Autoimmune Encephalomyelitis

Ann J. Canonigo-Balancio, Camille Fos, Thomas Prod'homme, Stéphane Bécart, and Amnon Altman
J Immunol 2009 183: 7259-7267. Published online November 13, 2009; doi:10.4049/jimmunol.0902573 [Abstract] [Full Text] [PDF] Data Supplement  

A Nonadjuvanted Polypeptide Nanoparticle Vaccine Confers Long-Lasting Protection against Rodent Malaria

Stephen A. Kaba, Clara Brando, Qin Guo, Christian Mittelholzer, Senthilkumar Raman, David Tropel, Ueli Aebi, Peter Burkhard, and David E. Lanar
J Immunol 2009 183: 7268-7277. Published online November 13, 2009; doi:10.4049/jimmunol.0901957 [Abstract] [Full Text] [PDF]  

Autophagic Compartments Gain Access to the MHC Class II Compartments in Thymic Epithelium

Michiyuki Kasai, Isei Tanida, Takashi Ueno, Eiki Kominami, Sachiko Seki, Tohru Ikeda, and Toshiaki Mizuochi
J Immunol 2009 183: 7278-7285. Published online November 13, 2009; doi:10.4049/jimmunol.0804087 [Abstract] [Full Text] [PDF]  

T Cell Intrinsic Heterodimeric Complexes between HVEM and BTLA Determine Receptivity to the Surrounding Microenvironment

Timothy C. Cheung, Lisa M. Oborne, Marcos W. Steinberg, Matthew G. Macauley, Satoshi Fukuyama, Hideki Sanjo, Claire D'Souza, Paula S. Norris, Klaus Pfeffer, Kenneth M. Murphy, Mitchell Kronenberg, Patricia G. Spear, and Carl F. Ware
J Immunol 2009 183: 7286-7296. Published online November 13, 2009; doi:10.4049/jimmunol.0902490 [Abstract] [Full Text] [PDF] Data Supplement  

Role of T Cell TGFβ Signaling and IL-17 in Allograft Acceptance and Fibrosis Associated with Chronic Rejection

Susan M. Faust, Guanyi Lu, Bernard L. Marini, Weiping Zou, David Gordon, Yoichiro Iwakura, Yasmina Laouar, and D. Keith Bishop
J Immunol 2009 183: 7297-7306. Published online November 16, 2009; doi:10.4049/jimmunol.0902446 [Abstract] [Full Text] [PDF]  

TGFβ Neutralization within Cardiac Allografts by Decorin Gene Transfer Attenuates Chronic Rejection

Susan M. Faust, Guanyi Lu, Sherri C. Wood, and D. Keith Bishop
J Immunol 2009 183: 7307-7313. Published online November 16, 2009; doi:10.4049/jimmunol.0902736 [Abstract] [Full Text] [PDF]  

Taking Advantage: High-Affinity B Cells in the Germinal Center Have Lower Death Rates, but Similar Rates of Division, Compared to Low-Affinity Cells

Shannon M. Anderson, Ashraf Khalil, Mohamed Uduman, Uri Hershberg, Yoram Louzoun, Ann M. Haberman, Steven H. Kleinstein, and Mark J. Shlomchik
J Immunol 2009 183: 7314-7325. Published online November 16, 2009; doi:10.4049/jimmunol.0902452 [Abstract] [Full Text] [PDF] Data Supplement  

Endogenous IL-21 Restricts CD8⁺ T Cell Expansion and Is not Required for Tumor Immunity

Henrik Søndergaard, Jonathan M. Coquet, Adam P. Uldrich, Nicole McLaughlin, Dale I. Godfrey, Pallavur V. Sivakumar, Kresten Skak, and Mark J. Smyth
J Immunol 2009 183: 7326-7336. Published online November 13, 2009; doi:10.4049/jimmunol.0902697 [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Dynamic Regulation of CXCR1 and CXCR2 Homo- and Heterodimers

Laura Martínez Muñoz, Pilar Lucas, Gemma Navarro, Ana I. Checa, Rafael Franco, Carlos Martínez-A., José Miguel Rodríguez-Frade, and Mario Mellado
J Immunol 2009 183: 7337-7346. Published online November 4, 2009; doi:10.4049/jimmunol.0901802 [Abstract] [Full Text] [PDF] Data Supplement  

Coexistence of Closed and Open Conformations of Complement Factor B in the Alternative Pathway C3bB(Mg²⁺) Proconvertase

Eva Torreira, Agustín Tortajada, Tamara Montes, Santiago Rodríguez de Córdoba, and Oscar Llorca
J Immunol 2009 183: 7347-7351. Published online November 4, 2009; doi:10.4049/jimmunol.0902310 [Abstract] [Full Text] [PDF]  

Hematopoietic Lineage Cell-Specific Protein 1 Is Recruited to the Immunological Synapse by IL-2-Inducible T Cell Kinase and Regulates Phospholipase C1 Microcluster Dynamics during T Cell Spreading

Esteban Carrizosa, Timothy S. Gomez, Christine M. Labno, Deborah A. Klos Dehring, Xiaohong Liu, Bruce D. Freedman, Daniel D. Billadeau, and Janis K. Burkhardt
J Immunol 2009 183: 7352-7361. Published online November 16, 2009; doi:10.4049/jimmunol.0900973 [Abstract] [Full Text] [PDF] Data Supplement  

Serine 649 Phosphorylation within the Protein Kinase C-Regulated Domain Down-Regulates CARMA1 Activity in Lymphocytes

Miguel E. Moreno-García, Karen Sommer, Claudia Haftmann, Clayton Sontheimer, Sarah F. Andrews, and David J. Rawlings
J Immunol 2009 183: 7362-7370. Published online November 16, 2009; doi:10.4049/jimmunol.0902438 [Abstract] [Full Text] [PDF] Data Supplement  

MAp44, a Human Protein Associated with Pattern Recognition Molecules of the Complement System and Regulating the Lectin Pathway of Complement Activation

Søren E. Degn, Annette G. Hansen, Rudi Steffensen, Christian Jacobsen, Jens C. Jensenius, and Steffen Thiel
J Immunol 2009 183: 7371-7378. Published online November 16, 2009; doi:10.4049/jimmunol.0902388 [Abstract] [Full Text] [PDF] Data Supplement  

Cytosolic Aminopeptidases Influence MHC Class I-Mediated Antigen Presentation in an Allele-Dependent Manner

Eunkyung Kim, Heechun Kwak, and Kwangseog Ahn
J Immunol 2009 183: 7379-7387. Published online November 16, 2009; doi:10.4049/jimmunol.0901489 [Abstract] [Full Text] [PDF]  

MAPK, Phosphatidylinositol 3-Kinase, and Mammalian Target of Rapamycin Pathways Converge at the Level of Ribosomal Protein S6 Phosphorylation to Control Metabolic Signaling in CD8 T Cells

Robert J. Salmond, Juliet Emery, Klaus Okkenhaug, and Rose Zamoyska
J Immunol 2009 183: 7388-7397. Published online November 16, 2009; doi:10.4049/jimmunol.0902294 [Abstract] [Full Text] [PDF] Data Supplement  

IMMUNOGENETICS:

The DC-SIGN of Zebrafish: Insights into the Existence of a CD209 Homologue in a Lower Vertebrate and Its Involvement in Adaptive Immunity

Ai-Fu Lin, Li-Xin Xiang, Qu-Long Wang, Wei-Ren Dong, Yong-Feng Gong, and Jian-Zhong Shao
J Immunol 2009 183: 7398-7410. Published online November 4, 2009; doi:10.4049/jimmunol.0803955 [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Increased Inflammation, Impaired Bacterial Clearance, and Metabolic Disruption after Gram-Negative Sepsis in Mkp-1-Deficient Mice

W. Joshua Frazier, Xianxi Wang, Lyn M. Wancket, Xiang-An Li, Xiaomei Meng, Leif D. Nelin, Andrew C. B. Cato, and Yusen Liu
J Immunol 2009 183: 7411-7419. Published online November 4, 2009; doi:10.4049/jimmunol.0804343 [Abstract] [Full Text] [PDF]  

Early Response of Mucosal Epithelial Cells during Toxoplasma gondii Infection

Chia-Hsin Ju, Annapoorani Chockalingam, and Cynthia A. Leifer
J Immunol 2009 183: 7420-7427. Published online November 16, 2009; doi:10.4049/jimmunol.0900640 [Abstract] [Full Text] [PDF] Data Supplement  

Immune Gene and Cell Enrichment Is Associated with a Good Prognosis in Ependymoma

Andrew M. Donson, Diane K. Birks, Valerie N. Barton, Qi Wei, Bette K. Kleinschmidt-DeMasters, Michael H. Handler, Allen E. Waziri, Michael Wang, and Nicholas K. Foreman
J Immunol 2009 183: 7428-7440. Published online November 16, 2009; doi:10.4049/jimmunol.0902811 [Abstract] [Full Text] [PDF]  

Neutrophils Ameliorate Lung Injury and the Development of Severe Disease during Influenza Infection

Michelle D. Tate, Yi-Mo Deng, Jessica E. Jones, Gary P. Anderson, Andrew G. Brooks, and Patrick C. Reading
J Immunol 2009 183: 7441-7450. Published online November 16, 2009; doi:10.4049/jimmunol.0902497 [Abstract] [Full Text] [PDF]  

Identification of Lipoteichoic Acid as a Ligand for Draper in the Phagocytosis of Staphylococcus aureus by Drosophila Hemocytes

Yumi Hashimoto, Yukichika Tabuchi, Kenji Sakurai, Mayumi Kutsuna, Kenji Kurokawa, Takeshi Awasaki, Kazuhisa Sekimizu, Yoshinobu Nakanishi, and Akiko Shiratsuchi
J Immunol 2009 183: 7451-7460. Published online November 4, 2009; doi:10.4049/jimmunol.0901032 [Abstract] [Full Text] [PDF]  

INFLAMMATION:

TLR Cross-Talk Specifically Regulates Cytokine Production by B Cells from Chronic Inflammatory Disease Patients

Madhumita Jagannathan, Hatice Hasturk, YanMei Liang, Hyunjin Shin, Jeremy T. Hetzel, Alpdogan Kantarci, Daniel Rubin, Marie E. McDonnell, Thomas E. Van Dyke, Lisa M. Ganley-Leal, and Barbara S. Nikolajczyk
J Immunol 2009 183: 7461-7470. Published online November 16, 2009; doi:10.4049/jimmunol.0901517 [Abstract] [Full Text] [PDF] Data Supplement  

Lipopolysaccharide Sensitizes Neonatal Hypoxic-Ischemic Brain Injury in a MyD88-Dependent Manner

Xiaoyang Wang, Linnea Stridh, Wenli Li, Justin Dean, Anders Elmgren, Liming Gan, Kristina Eriksson, Henrik Hagberg, and Carina Mallard
J Immunol 2009 183: 7471-7477. Published online November 16, 2009; doi:10.4049/jimmunol.0900762 [Abstract] [Full Text] [PDF]  

CCR5 Ligands Modulate CXCL12-Induced Chemotaxis, Adhesion, and Akt Phosphorylation of Human Cord Blood CD34⁺ Cells

Sunanda Basu and Hal E. Broxmeyer
J Immunol 2009 183: 7478-7488. Published online November 16, 2009; doi:10.4049/jimmunol.0900542 [Abstract] [Full Text] [PDF]  

The Oxazolidinone Derivative Locostatin Induces Cytokine Appeasement

Antoine Ménoret, Jeremy P. McAleer, Soo-Mun Ngoi, Swagatam Ray, Nicholas A. Eddy, Gabriel Fenteany, Seung-Joo Lee, Robert J. Rossi, Bijay Mukherji, David L. Allen, Nitya G. Chakraborty, and Anthony T. Vella
J Immunol 2009 183: 7489-7496. Published online November 16, 2009; doi:10.4049/jimmunol.0901414 [Abstract] [Full Text] [PDF] Data Supplement  

Calcium-Independent Phospholipase A₂β-Akt Signaling Is Involved in Lipopolysaccharide-Induced NADPH Oxidase 1 Expression and Foam Cell Formation

Sun-Hye Lee, Dae-Weon Park, Sung Chul Park, Yun-Ki Park, Seong Yeon Hong, Jae-Ryong Kim, Chu-Hee Lee, and Suk-Hwan Baek
J Immunol 2009 183: 7497-7504. Published online November 16, 2009; doi:10.4049/jimmunol.0900503 [Abstract] [Full Text] [PDF]  

CD80 Blockade Enhance Glucocorticoid-Induced Leucine Zipper Expression and Suppress Experimental Autoimmune Encephalomyelitis

Shailesh P. Dudhgaonkar, Srihari B. Janardhanam, Krithika N. Kodumudi, and Mythily Srinivasan
J Immunol 2009 183: 7505-7513. Published online November 16, 2009; doi:10.4049/jimmunol.0902056 [Abstract] [Full Text] [PDF]  

G Protein-Coupled Receptor 43 Is Essential for Neutrophil Recruitment during Intestinal Inflammation

Christian Sina, Olga Gavrilova, Matti Förster, Andreas Till, Stefanie Derer, Friederike Hildebrand, Björn Raabe, Athena Chalaris, Jürgen Scheller, Ateequr Rehmann, Andre Franke, Stephan Ott, Robert Häsler, Susanna Nikolaus, Ulrich R. Fölsch, Stefan Rose-John, Hui-Ping Jiang, Jun Li, Stefan Schreiber, and Philip Rosenstiel
J Immunol 2009 183: 7514-7522. Published online November 16, 2009; doi:10.4049/jimmunol.0900063 [Abstract] [Full Text] [PDF] Data Supplement  

Natural Occurring IL-17 Producing T Cells Regulate the Initial Phase of Neutrophil Mediated Airway Responses

Shinya Tanaka, Takayuki Yoshimoto, Tetsuji Naka, Susumu Nakae, Yo-ichi Iwakura, Daniel Cua, and Masato Kubo
J Immunol 2009 183: 7523-7530. Published online November 4, 2009; doi:10.4049/jimmunol.0803828 [Abstract] [Full Text] [PDF]  

Fms-Like Tyrosine Kinase 3 Ligand Regulates Migratory Pattern and Antigen Uptake of Lung Dendritic Cell Subsets in a Murine Model of Allergic Airway Inflammation

Zhifei Shao, Toluwalope O. Makinde, Halvor S. McGee, Xiang Wang, and Devendra K. Agrawal
J Immunol 2009 183: 7531-7538. Published online November 16, 2009; doi:10.4049/jimmunol.0901341 [Abstract] [Full Text] [PDF]  

Tyrosine Kinase 2 Plays Critical Roles in the Pathogenic CD4 T Cell Responses for the Development of Experimental Autoimmune Encephalomyelitis

Akiko Oyamada, Hiori Ikebe, Momoe Itsumi, Hirokazu Saiwai, Seiji Okada, Kazuya Shimoda, Yoichiro Iwakura, Keiichi I. Nakayama, Yukihide Iwamoto, Yasunobu Yoshikai, and Hisakata Yamada
J Immunol 2009 183: 7539-7546. Published online November 16, 2009; doi:10.4049/jimmunol.0902740 [Abstract] [Full Text] [PDF]  

Unlike Th1, Th17 Cells Mediate Sustained Autoimmune Inflammation and Are Highly Resistant to Restimulation-Induced Cell Death

Guangpu Shi, Madhu Ramaswamy, Barbara P. Vistica, Catherine A. Cox, Cuiyan Tan, Eric F. Wawrousek, Richard M. Siegel, and Igal Gery
J Immunol 2009 183: 7547-7556. Published online November 4, 2009; doi:10.4049/jimmunol.0900519 [Abstract] [Full Text] [PDF]  

Selective Down-Regulation of Neutrophil Mac-1 in Endotoxemic Hepatic Microcirculation via IL-10

Gustavo Batista Menezes, Woo-Yong Lee, Hong Zhou, Christopher Curtis Matchett Waterhouse, Denise Carmona Cara, and Paul Kubes
J Immunol 2009 183: 7557-7568. Published online November 16, 2009; doi:10.4049/jimmunol.0901786 [Abstract] [Full Text] [PDF] Data Supplement  

CLINICAL IMMUNOLOGY:

Systematic Classification of Primary Immunodeficiencies Based on Clinical, Pathological, and Laboratory Parameters

Crina Samarghitean, Csaba Ortutay, and Mauno Vihinen
J Immunol 2009 183: 7569-7575. Published online November 16, 2009; doi:10.4049/jimmunol.0901837 [Abstract] [Full Text] [PDF] Data Supplement  

The Cutaneous Biochemical Redox Barrier: A Component of the Innate Immune Defenses against Sensitization by Highly Reactive Environmental Xenobiotics

Chris Pickard, Fethi Louafi, Carolann McGuire, Kelly Lowings, Pawan Kumar, Hywel Cooper, Rebecca J. Dearman, Marie Cumberbatch, Ian Kimber, Eugene Healy, and Peter S. Friedmann
J Immunol 2009 183: 7576-7584. Published online November 4, 2009; doi:10.4049/jimmunol.0901064 [Abstract] [Full Text] [PDF]  

β Cell-Specific CD4⁺ T Cell Clonotypes in Peripheral Blood and the Pancreatic Islets Are Distinct

Li Li, Qiuming He, Alaina Garland, Zuoan Yi, Lydia T. Aybar, Thomas B. Kepler, Jeffrey A. Frelinger, Bo Wang, and Roland Tisch
J Immunol 2009 183: 7585-7591. Published online November 16, 2009; doi:10.4049/jimmunol.0901587 [Abstract] [Full Text] [PDF] Data Supplement  

Immunomodulation of Nasal Epithelial Cells by Staphylococcus aureus-Derived Serine Proteases

Claudia Rudack, Florian Sachse, Nils Albert, Karsten Becker, and Christof von Eiff
J Immunol 2009 183: 7592-7601. Published online November 16, 2009; doi:10.4049/jimmunol.0803902 [Abstract] [Full Text] [PDF]  

CD39⁺Foxp3⁺ Regulatory T Cells Suppress Pathogenic Th17 Cells and Are Impaired in Multiple Sclerosis

Jean M. Fletcher, Roisin Lonergan, Lisa Costelloe, Katie Kinsella, Barry Moran, Cliona O'Farrelly, Niall Tubridy, and Kingston H. G. Mills
J Immunol 2009 183: 7602-7610. Published online November 16, 2009; doi:10.4049/jimmunol.0901881 [Abstract] [Full Text] [PDF]  

CORRECTIONS:

HIV-1 Nef promotes endocytosis of cell surface MHC class II molecules via a constitutive pathway

A. Chaudhry, D. A. Verghese, S. R. Das, S. Jameel, A. George, V. Bal, S. Mayor, and S. Rath
J Immunol 2009 183: 7611; doi:10.4049/jimmunol.0990098 [Full Text] [PDF]  

Adenovirus vector-induced immune responses in nonhuman primates: responses to prime boost regimens

N. Tatsis, M. O. Lasaro, S.-W. Lin, Z. Q. Xiang, D. Zhou, L. DiMenna, H. Li, A. Bian, S. Abdulla, Y. Li, W. Giles-Davis, J. Engram, S. J. Ratcliffe, G. Silvestri, H. C. Ertl, and M. R. Betts
J Immunol 2009 183: 7611; doi:10.4049/jimmunol.0990099 [Full Text] [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.