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On the cover: Receptor activator of NF-κB ligand (RANKL) induces differentiation of microfold (M) cells. A whole mount fluorescence micrograph of ileum from BALB/c mice treated with the cytokine RANKL for 4 days reveals M cells detected with rhodamine-conjugated Ulex europaeus agglutinin-I in diffuse or dense patterns on all villi. Knoop, K. A., N. Kumar, B. R. Butler, S. K. Sakthivel, R. T. Taylor, T. Nochi, H. Akiba, H. Yagita, H. Kiyono, and I. R. Williams. 2009. RANKL Is Necessary and Sufficient to Initiate Development of Antigen-Sampling M Cells in the Intestinal Epithelium. J. Immunol 183: 5738–5747.
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