IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2009 183: 4143-4144; doi:10.4049/jimmunol.0990080 [Full Text] [PDF] ImmunoCast  

LETTERS TO THE EDITOR:

Comment on "Proteasome Regulation of ULBP1 Transcription"

Alejandro López-Soto and Segundo González
J Immunol 2009 183: 4145; doi:10.4049/jimmunol.0990075 [Full Text] [PDF]  

Response to Comment on "Proteasome Regulation of ULBP1 Transcription"

Charles T. Lutz, James E. Butler, Steven R. Presnell, Huei-Wei Chan, and N. Jan Chalupny
J Immunol 2009 183: 4145-4146; doi:10.4049/jimmunol.0990076 [Full Text] [PDF]  

Comment on "The Bacterial Fermentation Product Butyrate Influences Epithelial Signaling via Reactive Oxygen Species-Mediated Changes in Cullin-1 Neddylation"

Evelyn Png, Jyk-Kuen Siak, Jamie Chew, and Louis Tong
J Immunol 2009 183: 4146; doi:10.4049/jimmunol.0990077 [Full Text] [PDF]  

PILLARS OF IMMUNOLOGY:

How Suppressor Cells Led to Anergy, Costimulation, and Beyond

Hélène Bour-Jordan and Jeffery A. Bluestone
J Immunol 2009 183: 4147-4149; doi:10.4049/jimmunol.0990078 [Full Text] [PDF] [Original Pillars Article]  

Pillars Article: Antigen Presentation by Chemically Modified Splenocytes Induces Antigen-Specific T Cell Unresponsiveness In Vitro and In Vivo. J. Exp. Med. 1987. 165: 302–319

Marc K. Jenkins and Ronald H. Schwartz
J Immunol 2009 183: 4150-4167 [PDF]  

BRIEF REVIEWS:

Protumor vs Antitumor Functions of IL-17

Gopal Murugaiyan and Bhaskar Saha
J Immunol 2009 183: 4169-4175; doi:10.4049/jimmunol.0901017 [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: Contribution of Lung-Resident T Cell Proliferation to the Overall Magnitude of the Antigen-Specific CD8 T Cell Response in the Lungs following Murine Influenza Virus Infection

Jodi McGill and Kevin L. Legge
J Immunol 2009 183: 4177-4181. Published online October 1, 2009; doi:10.4049/jimmunol.0901109 [Abstract] [Full Text] [PDF] Data Supplement  

Cutting Edge: CD4-Independent Development of Functional FoxP3⁺ Regulatory T Cells

Céline Blache, Sahil Adriouch, Sébastien Calbo, Laurent Drouot, Sophie Dulauroy, Christophe Arnoult, Stéphanie Le Corre, Adrien Six, Michel Seman, and Olivier Boyer
J Immunol 2009 183: 4182-4186. Published online October 1, 2009; doi:10.4049/jimmunol.0901678 [Abstract] [Full Text] [PDF] Data Supplement  

Cutting Edge: HLA-DM Functions through a Mechanism That Does Not Require Specific Conserved Hydrogen Bonds in Class II MHC-Peptide Complexes

Zemin Zhou, Kari A. Callaway, Dominique A. Weber, and Peter E. Jensen
J Immunol 2009 183: 4187-4191. Published online October 1, 2009; doi:10.4049/jimmunol.0901663 [Abstract] [Full Text] [PDF] Data Supplement  

Cutting Edge: Dab2 Is a FOXP3 Target Gene Required for Regulatory T Cell Function

Nitya Jain, Hai Nguyen, Randall H. Friedline, Nidhi Malhotra, Michael Brehm, Madoka Koyanagi, Mark Bix, Jonathan A. Cooper, Cynthia A. Chambers, and Joonsoo Kang
J Immunol 2009 183: 4192-4196. Published online October 1, 2009; doi:10.4049/jimmunol.0902041 [Abstract] [Full Text] [PDF] Data Supplement  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

MS4A4B Is a GITR-Associated Membrane Adapter, Expressed by Regulatory T Cells, Which Modulates T Cell Activation

Duncan Howie, Kathleen F. Nolan, Stephen Daley, Emma Butterfield, Elizabeth Adams, Hugo Garcia-Rueda, Claire Thompson, Nigel J. Saunders, Stephen P. Cobbold, Yukiko Tone, Masahide Tone, and Herman Waldmann
J Immunol 2009 183: 4197-4204. Published online September 14, 2009; doi:10.4049/jimmunol.0901070 [Abstract] [Full Text] [PDF] Data Supplement  

Efficient Cross-Priming of Antiviral CD8⁺ T Cells by Antigen Donor Cells Is GRP94 Independent

Avital Lev, Peniel Dimberu, Suman R. Das, Jason C. Maynard, Christopher V. Nicchitta, Jack R. Bennink, and Jonathan W. Yewdell
J Immunol 2009 183: 4205-4210. Published online September 14, 2009; doi:10.4049/jimmunol.0901828 [Abstract] [Full Text] [PDF]  

Sustained and NK/CD4⁺ T Cell-Dependent Efficient Prevention of Lung Metastasis Induced by Dendritic Cells Harboring Recombinant Sendai Virus

Atsushi Komaru, Yasuji Ueda, Aki Furuya, Sakura Tanaka, Kumi Yoshida, Tomonori Kato, Hiroaki Kinoh, Yui Harada, Hiroyoshi Suzuki, Makoto Inoue, Mamoru Hasegawa, Tomohiko Ichikawa, and Yoshikazu Yonemitsu
J Immunol 2009 183: 4211-4219. Published online September 4, 2009; doi:10.4049/jimmunol.0803845 [Abstract] [Full Text] [PDF] Data Supplement  

CRTAM Confers Late-Stage Activation of CD8⁺ T Cells to Regulate Retention within Lymph Node

Arata Takeuchi, Yasushi Itoh, Akiko Takumi, Chitose Ishihara, Noriko Arase, Tadashi Yokosuka, Haruhiko Koseki, Sho Yamasaki, Yoshimi Takai, Jun Miyoshi, Kazumasa Ogasawara, and Takashi Saito
J Immunol 2009 183: 4220-4228. Published online September 14, 2009; doi:10.4049/jimmunol.0901248 [Abstract] [Full Text] [PDF] Data Supplement  

IL-11 Regulates Autoimmune Demyelination

Blake T. Gurfein, Yueting Zhang, Carolina B. López, Azeb Tadesse Argaw, Andleeb Zameer, Thomas M. Moran, and Gareth R. John
J Immunol 2009 183: 4229-4240. Published online September 4, 2009; doi:10.4049/jimmunol.0900622 [Abstract] [Full Text] [PDF] Data Supplement  

Negative Regulation of MAVS-Mediated Innate Immune Response by PSMA7

Yongxia Jia, Ting Song, Congwen Wei, Caifei Ni, Zirui Zheng, Quanbin Xu, Hongfang Ma, Li Li, Yanhong Zhang, Xiang He, Yang Xu, Wei Shi, and Hui Zhong
J Immunol 2009 183: 4241-4248. Published online September 4, 2009; doi:10.4049/jimmunol.0901646 [Abstract] [Full Text] [PDF]  

The Toll-IL-1R Member Tir8/SIGIRR Negatively Regulates Adaptive Immunity against Kidney Grafts

Marina Noris, Paola Cassis, Nadia Azzollini, Regiane Cavinato, Daniela Cugini, Federica Casiraghi, Sistiana Aiello, Samantha Solini, Linda Cassis, Marilena Mister, Marta Todeschini, Mauro Abbate, Ariela Benigni, Piera Trionfini, Susanna Tomasoni, Caterina Mele, Cecilia Garlanda, Nadia Polentarutti, Alberto Mantovani, and Giuseppe Remuzzi
J Immunol 2009 183: 4249-4260. Published online September 4, 2009; doi:10.4049/jimmunol.0803549 [Abstract] [Full Text] [PDF] [Extended Methods] [Data Supplement]  

The Immunological Impact of Genetic Drift in the B10.BR Congenic Inbred Mouse Strain

Stacey L. Fanning, Michael Y. Appel, Stephanie A. Berger, Robert Korngold, and Thea M. Friedman
J Immunol 2009 183: 4261-4272. Published online September 14, 2009; doi:10.4049/jimmunol.0900971 [Abstract] [Full Text] [PDF]  

Fluid Flow Regulates Stromal Cell Organization and CCL21 Expression in a Tissue-Engineered Lymph Node Microenvironment

Alice A. Tomei, Stefanie Siegert, Mirjam R. Britschgi, Sanjiv A. Luther, and Melody A. Swartz
J Immunol 2009 183: 4273-4283. Published online September 4, 2009; doi:10.4049/jimmunol.0900835 [Abstract] [Full Text] [PDF]  

Reviving Function in CD4⁺ T Cells Adapted to Persistent Systemic Antigen

Magali Noval Rivas, Kathleen Weatherly, Marc Hazzan, Benoit Vokaer, Sarah Dremier, Florence Gaudray, Michel Goldman, Isabelle Salmon, and Michel Y. Braun
J Immunol 2009 183: 4284-4291. Published online September 4, 2009; doi:10.4049/jimmunol.0901408 [Abstract] [Full Text] [PDF] Data Supplement  

Discontinued Postnatal Thymocyte Development in Sphingosine 1-Phosphate-Lyase-Deficient Mice

Claudia Weber, Andreas Krueger, Anika Münk, Constantin Bode, Paul P. Van Veldhoven, and Markus H. Gräler
J Immunol 2009 183: 4292-4301. Published online September 11, 2009; doi:10.4049/jimmunol.0901724 [Abstract] [Full Text] [PDF] Data Supplement  

Extracellular ATP Acting at the P2X₇ Receptor Inhibits Secretion of Soluble HLA-G from Human Monocytes

Roberta Rizzo, Davide Ferrari, Loredana Melchiorri, Marina Stignani, Sara Gulinelli, Olavio R. Baricordi, and Francesco Di Virgilio
J Immunol 2009 183: 4302-4311. Published online September 11, 2009; doi:10.4049/jimmunol.0804265 [Abstract] [Full Text] [PDF]  

Reciprocal Human Dendritic Cell–Natural Killer Cell Interactions Induce Antitumor Activity Following Tumor Cell Infection by Oncolytic Reovirus

Robin J. Prestwich, Fiona Errington, Lynette P. Steele, Elizabeth J. Ilett, Ruth S. M. Morgan, Kevin J. Harrington, Hardev S. Pandha, Peter J. Selby, Richard G. Vile, and Alan A. Melcher
J Immunol 2009 183: 4312-4321. Published online September 4, 2009; doi:10.4049/jimmunol.0901074 [Abstract] [Full Text] [PDF]  

Formula Feeding Skews Immune Cell Composition toward Adaptive Immunity Compared to Breastfeeding

Yvonne Andersson, Marie-Louise Hammarström, Bo Lönnerdal, Gitte Graverholt, Helen Fält, and Olle Hernell
J Immunol 2009 183: 4322-4328. Published online September 4, 2009; doi:10.4049/jimmunol.0900829 [Abstract] [Full Text] [PDF]  

Quantifying Thymic Export: Combining Models of Naive T Cell Proliferation and TCR Excision Circle Dynamics Gives an Explicit Measure of Thymic Output

Iren Bains, Rodolphe Thiébaut, Andrew J. Yates, and Robin Callard
J Immunol 2009 183: 4329-4336. Published online September 4, 2009; doi:10.4049/jimmunol.0900743 [Abstract] [Full Text] [PDF]  

Quantitating T Cell Cross-Reactivity for Unrelated Peptide Antigens

Jeffrey Ishizuka, Kristie Grebe, Eugene Shenderov, Bjoern Peters, Qiongyu Chen, YanChun Peng, Lili Wang, Tao Dong, Valerie Pasquetto, Carla Oseroff, John Sidney, Heather Hickman, Vincenzo Cerundolo, Alessandro Sette, Jack R. Bennink, Andrew McMichael, and Jonathan W. Yewdell
J Immunol 2009 183: 4337-4345. Published online September 4, 2009; doi:10.4049/jimmunol.0901607 [Abstract] [Full Text] [PDF] Data Supplement  

Induction of Alloantigen-Specific Human T Regulatory Cells by Vasoactive Intestinal Peptide

David Pozo, Per Anderson, and Elena Gonzalez-Rey
J Immunol 2009 183: 4346-4359. Published online September 4, 2009; doi:10.4049/jimmunol.0900400 [Abstract] [Full Text] [PDF]  

Dynamic Development of Homing Receptor Expression and Memory Cell Differentiation of Infant CD4⁺CD25^high Regulatory T Cells

Hanna Grindebacke, Hanna Stenstad, Marianne Quiding-Järbrink, Jesper Waldenström, Ingegerd Adlerberth, Agnes E. Wold, and Anna Rudin
J Immunol 2009 183: 4360-4370. Published online September 4, 2009; doi:10.4049/jimmunol.0901091 [Abstract] [Full Text] [PDF]  

Phosphorothioate-Modified TLR9 Ligands Protect Cancer Cells against TRAIL-Induced Apoptosis

David Chiron, Catherine Pellat-Deceunynck, Mike Maillasson, Régis Bataille, and Gaëtan Jego
J Immunol 2009 183: 4371-4377. Published online September 4, 2009; doi:10.4049/jimmunol.0901436 [Abstract] [Full Text] [PDF] Data Supplement  

CXCR3 Directs Antigen-Specific Effector CD4⁺ T Cell Migration to the Lung During Parainfluenza Virus Infection

Jacob E. Kohlmeier, Tres Cookenham, Shannon C. Miller, Alan D. Roberts, Jan P. Christensen, Allan R. Thomsen, and David L. Woodland
J Immunol 2009 183: 4378-4384. Published online September 4, 2009; doi:10.4049/jimmunol.0902022 [Abstract] [Full Text] [PDF]  

Heat Shock Protein-90 Inhibitors Increase MHC Class I-Related Chain A and B Ligand Expression on Multiple Myeloma Cells and Their Ability to Trigger NK Cell Degranulation

Cinzia Fionda, Alessandra Soriani, Giulia Malgarini, Maria Luisa Iannitto, Angela Santoni, and Marco Cippitelli
J Immunol 2009 183: 4385-4394. Published online September 11, 2009; doi:10.4049/jimmunol.0901797 [Abstract] [Full Text] [PDF] Data Supplement  

Impaired Mast Cell Activation in Gene-Targeted Mice Lacking the Serum- and Glucocorticoid-Inducible Kinase SGK1

Malgorzata Sobiesiak, Ekaterina Shumilina, Rebecca S. Lam, Florian Wölbing, Nicole Matzner, Susanne Kaesler, Irina M. Zemtsova, Adrian Lupescu, Naima Zahir, Dietmar Kuhl, Martin Schaller, Tilo Biedermann, and Florian Lang
J Immunol 2009 183: 4395-4402. Published online September 11, 2009; doi:10.4049/jimmunol.0803017 [Abstract] [Full Text] [PDF]  

Alum Induces Innate Immune Responses through Macrophage and Mast Cell Sensors, But These Sensors Are Not Required for Alum to Act As an Adjuvant for Specific Immunity

Amy S. McKee, Michael W. Munks, Megan K. L. MacLeod, Courtney J. Fleenor, Nico Van Rooijen, John W. Kappler, and Philippa Marrack
J Immunol 2009 183: 4403-4414. Published online September 4, 2009; doi:10.4049/jimmunol.0900164 [Abstract] [Full Text] [PDF] Data Supplement  

Invariant TCR Rather Than CD1d Shapes the Preferential Activities of C-Glycoside Analogues Against Human Versus Murine Invariant NKT Cells

Xiangming Li, Takayuki Shiratsuchi, Guangwu Chen, Paolo Dellabona, Giulia Casorati, Richard W. Franck, and Moriya Tsuji
J Immunol 2009 183: 4415-4421. Published online September 4, 2009; doi:10.4049/jimmunol.0901021 [Abstract] [Full Text] [PDF]  

TLR3 Ligand Polyinosinic:Polycytidylic Acid Induces IL-17A and IL-21 Synthesis in Human Th Cells

Christian K. Holm, Charlotte C. Petersen, Malene Hvid, Line Petersen, Søren R. Paludan, Bent Deleuran, and Marianne Hokland
J Immunol 2009 183: 4422-4431. Published online September 11, 2009; doi:10.4049/jimmunol.0804318 [Abstract] [Full Text] [PDF]  

Monocytes from Patients with Type 1 Diabetes Spontaneously Secrete Proinflammatory Cytokines Inducing Th17 Cells

Elizabeth M. Bradshaw, Khadir Raddassi, Wassim Elyaman, Tihamer Orban, Peter A. Gottlieb, Sally C. Kent, and David A. Hafler
J Immunol 2009 183: 4432-4439. Published online September 11, 2009; doi:10.4049/jimmunol.0900576 [Abstract] [Full Text] [PDF] Data Supplement  

The ssRNA Genome of Human Rhinovirus Induces a Type I IFN Response but Fails to Induce Maturation in Human Monocyte-Derived Dendritic Cells

Catharina Schrauf, Stefanie Kirchberger, Otto Majdic, Maria Seyerl, Gerhard-Johann Zlabinger, Karl Manfred Stuhlmeier, Monika Sachet, Joachim Seipelt, and Johannes Stöckl
J Immunol 2009 183: 4440-4448. Published online September 4, 2009; doi:10.4049/jimmunol.0804147 [Abstract] [Full Text] [PDF]  

Differentiation-Associated Loss of Ryanodine Receptors: A Strategy Adopted by Monocytes/Macrophages to Prevent the DNA Single-Strand Breakage Induced by Peroxynitrite

Andrea Guidarelli, Liana Cerioni, Mara Fiorani, and Orazio Cantoni
J Immunol 2009 183: 4449-4457. Published online September 4, 2009; doi:10.4049/jimmunol.0901260 [Abstract] [Full Text] [PDF]  

Engagement of TLR2 Does not Reverse the Suppressor Function of Mouse Regulatory T Cells, but Promotes Their Survival

Qian Chen, Todd S. Davidson, Eva N. Huter, and Ethan M. Shevach
J Immunol 2009 183: 4458-4466. Published online September 11, 2009; doi:10.4049/jimmunol.0901465 [Abstract] [Full Text] [PDF]  

ThPOK Derepression Is Required for Robust CD8 T cell Responses to Viral Infection

Ruka Setoguchi, Ichiro Taniuchi, and Michael J. Bevan
J Immunol 2009 183: 4467-4474. Published online September 4, 2009; doi:10.4049/jimmunol.0901428 [Abstract] [Full Text] [PDF] Data Supplement  

c-Jun Controls the Ability of IL-12 to Induce IL-10 Production from Human Memory CD4⁺ T Cells

Carlos A. Garcia, Huizhi Wang, Manjunatha R. Benakanakere, Elyse Barrett, Denis F. Kinane, and Michael Martin
J Immunol 2009 183: 4475-4482. Published online September 4, 2009; doi:10.4049/jimmunol.0901283 [Abstract] [Full Text] [PDF]  

Developmental Switch of the Expression of Ion Channels in Human Dendritic Cells

Emese Zsiros, Katalin Kis-Toth, Peter Hajdu, Rezso Gaspar, Joanna Bielanska, Antonio Felipe, Eva Rajnavolgyi, and Gyorgy Panyi
J Immunol 2009 183: 4483-4492. Published online September 11, 2009; doi:10.4049/jimmunol.0803003 [Abstract] [Full Text] [PDF]  

Cell Cycle Progression following Naive T Cell Activation Is Independent of Jak3/Common -Chain Cytokine Signals

Min Shi, Tsung H. Lin, Kenneth C. Appell, and Leslie J. Berg
J Immunol 2009 183: 4493-4501. Published online September 4, 2009; doi:10.4049/jimmunol.0804339 [Abstract] [Full Text] [PDF] Data Supplement  

Killer Ig-Like Receptor Ligand Mismatch Directs NK Cell Expansion In Vitro

Mingus J. J. Rose, Andrew G. Brooks, Lisbeth A. Stewart, Thi H. Nguyen, and Anthony P. Schwarer
J Immunol 2009 183: 4502-4508. Published online September 11, 2009; doi:10.4049/jimmunol.0803323 [Abstract] [Full Text] [PDF]  

The Inhibitory FcIIb Receptor Dampens TLR4-Mediated Immune Responses and Is Selectively Up-regulated on Dendritic Cells from Rheumatoid Arthritis Patients with Quiescent Disease

Mark H. Wenink, Kim C. M. Santegoets, Mieke F. Roelofs, Richard Huijbens, Hans J. P. M. Koenen, Ronald van Beek, Irma Joosten, Friederike Meyer-Wentrup, Linda Mathsson, Johan Ronnelid, Gosse J. Adema, Ezio Bonvini, Scott Koenig, Wim B. van den Berg, Piet L. C. M. van Riel, and Timothy R. D. J. Radstake
J Immunol 2009 183: 4509-4520. Published online September 4, 2009; doi:10.4049/jimmunol.0900153 [Abstract] [Full Text] [PDF]  

P2Y₂ Receptor Transcription Is Increased by NF-B and Stimulates Cyclooxygenase-2 Expression and PGE₂ Released by Intestinal Epithelial Cells

Emilie Degagné, Djordje M. Grbic, Andrée-Anne Dupuis, Elise G. Lavoie, Christine Langlois, Nishant Jain, Gary A. Weisman, Jean Sévigny, and Fernand-Pierre Gendron
J Immunol 2009 183: 4521-4529. Published online September 4, 2009; doi:10.4049/jimmunol.0803977 [Abstract] [Full Text] [PDF] Data Supplement  

Antitumor IgE Adjuvanticity: Key Role of FcRI

Elisa A. Nigro, Anna T. Brini, Elisa Soprana, Alessandro Ambrosi, David Dombrowicz, Antonio G. Siccardi, and Luca Vangelista
J Immunol 2009 183: 4530-4536. Published online September 11, 2009; doi:10.4049/jimmunol.0900842 [Abstract] [Full Text] [PDF]  

SOCS-1 Binding to Tyrosine 441 of IFN- Receptor Subunit 1 Contributes to the Attenuation of IFN- Signaling In Vivo

Robyn Starr, Martina Fuchsberger, Lei Shong Lau, Adam P. Uldrich, Ankita Goradia, Tracy A. Willson, Anne M. Verhagen, Warren S. Alexander, and Mark J. Smyth
J Immunol 2009 183: 4537-4544. Published online September 4, 2009; doi:10.4049/jimmunol.0901010 [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Temporal Regulation of Ig Gene Diversification Revealed by Single-Cell Imaging

Ellen C. Ordinario, Munehisa Yabuki, Ryan P. Larson, and Nancy Maizels
J Immunol 2009 183: 4545-4553. Published online September 11, 2009; doi:10.4049/jimmunol.0900673 [Abstract] [Full Text] [PDF]  

Chicken IgY Binds Its Receptor at the C_H3/C_H4 Interface Similarly as the Human IgA:FcRI Interaction

Jana Pürzel, Ramona Schmitt, Birgit C. Viertlboeck, and Thomas W. Göbel
J Immunol 2009 183: 4554-4559. Published online September 11, 2009; doi:10.4049/jimmunol.0901699 [Abstract] [Full Text] [PDF]  

IMMUNOGENETICS:

Genomic and Functional Uniqueness of the TNF Receptor-Associated Factor Gene Family in Amphioxus, the Basal Chordate

Shaochun Yuan, Tong Liu, Shengfeng Huang, Tao Wu, Ling Huang, Huiling Liu, Xin Tao, Manyi Yang, Kui Wu, Yanhong Yu, Meiling Dong, and Anlong Xu
J Immunol 2009 183: 4560-4568. Published online September 14, 2009; doi:10.4049/jimmunol.0901537 [Abstract] [Full Text] [PDF] Data Supplement  

Dimorphic Motifs in D0 and D1+D2 Domains of Killer Cell Ig-Like Receptor 3DL1 Combine to Form Receptors with High, Moderate, and No Avidity for the Complex of a Peptide Derived from HIV and HLA-A*2402

Deepti Sharma, Karine Bastard, Lisbeth A. Guethlein, Paul J. Norman, Nobuyo Yawata, Makoto Yawata, Marcelo Pando, Hathairat Thananchai, Tao Dong, Sarah Rowland-Jones, Frances M. Brodsky, and Peter Parham
J Immunol 2009 183: 4569-4582. Published online September 14, 2009; doi:10.4049/jimmunol.0901734 [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Bacterial Surface Protein L Binds and Inactivates Neutrophil Proteins S100A8/A9

Bo Åkerström and Lars Björck
J Immunol 2009 183: 4583-4592. Published online September 14, 2009; doi:10.4049/jimmunol.0901487 [Abstract] [Full Text] [PDF]  

A Novel Role for Plasmin-Mediated Degradation of Opsonizing Antibody in the Evasion of Host Immunity by Virulent, but Not Attenuated, Francisella tularensis

Deborah D. Crane, Shayna L. Warner, and Catharine M. Bosio
J Immunol 2009 183: 4593-4600. Published online September 14, 2009; doi:10.4049/jimmunol.0901655 [Abstract] [Full Text] [PDF]  

Innate Immunity against Bacterial Infection following Hyperoxia Exposure Is Impaired in NRF2-Deficient Mice

Narsa M. Reddy, Vegiraju Suryanarayana, Dhananjaya V. Kalvakolanu, Masayuki Yamamoto, Thomas W. Kensler, Paul M. Hassoun, Steven R. Kleeberger, and Sekhar P. Reddy
J Immunol 2009 183: 4601-4608. Published online September 4, 2009; doi:10.4049/jimmunol.0901754 [Abstract] [Full Text] [PDF] Data Supplement  

Exogenous Pentraxin 3 Restores Antifungal Resistance and Restrains Inflammation in Murine Chronic Granulomatous Disease

Carmen D'Angelo, Antonella De Luca, Teresa Zelante, Pierluigi Bonifazi, Silvia Moretti, Gloria Giovannini, Rossana Giulietta Iannitti, Silvia Zagarella, Silvia Bozza, Silvia Campo, Giovanni Salvatori, and Luigina Romani
J Immunol 2009 183: 4609-4618. Published online September 4, 2009; doi:10.4049/jimmunol.0900345 [Abstract] [Full Text] [PDF]  

IL-27 Regulates IL-10 and IL-17 from CD4⁺ Cells in Nonhealing Leishmania major Infection

Charles F. Anderson, Jason S. Stumhofer, Christopher A. Hunter, and David Sacks
J Immunol 2009 183: 4619-4627. Published online September 11, 2009; doi:10.4049/jimmunol.0804024 [Abstract] [Full Text] [PDF]  

Beneficial Immunomodulation by Streptococcus mutans Anti-P1 Monoclonal Antibodies Is Fc Independent and Correlates with Increased Exposure of a Relevant Target Epitope

Rebekah A. Robinette, Monika W. Oli, William P. McArthur, and L. Jeannine Brady
J Immunol 2009 183: 4628-4638. Published online September 14, 2009; doi:10.4049/jimmunol.0803300 [Abstract] [Full Text] [PDF]  

Furin-Processed Antigens Targeted to the Secretory Route Elicit Functional TAP1^–/–CD8⁺ T Lymphocytes In Vivo

Francisco Medina, Manuel Ramos, Salvador Iborra, Patricia de León, Marta Rodríguez-Castro, and Margarita Del Val
J Immunol 2009 183: 4639-4647. Published online September 14, 2009; doi:10.4049/jimmunol.0901356 [Abstract] [Full Text] [PDF]  

INFLAMMATION:

The Proinflammatory Action of Microglial P2 Receptors Is Enhanced in SOD1 Models for Amyotrophic Lateral Sclerosis

Nadia D'Ambrosi, Pamela Finocchi, Savina Apolloni, Mauro Cozzolino, Alberto Ferri, Valeria Padovano, Grazia Pietrini, Maria Teresa Carrì, and Cinzia Volonté
J Immunol 2009 183: 4648-4656. Published online September 4, 2009; doi:10.4049/jimmunol.0901212 [Abstract] [Full Text] [PDF]  

Human Mast Cells Adhere to and Migrate on Epithelial and Vascular Basement Membrane Laminins LM-332 and LM-511 via ₃β₁ Integrin

Wondossen Sime, Carolina Lunderius-Andersson, Mattias Enoksson, Patricia Rousselle, Karl Tryggvason, Gunnar Nilsson, Ilkka Harvima, and Manuel Patarroyo
J Immunol 2009 183: 4657-4665. Published online September 14, 2009; doi:10.4049/jimmunol.0901738 [Abstract] [Full Text] [PDF]  

IL-13-Induced Oxidative Stress via Microglial NADPH Oxidase Contributes to Death of Hippocampal Neurons In Vivo

Keun W. Park, Hyung H. Baik, and Byung K. Jin
J Immunol 2009 183: 4666-4674. Published online September 14, 2009; doi:10.4049/jimmunol.0803392 [Abstract] [Full Text] [PDF] Data Supplement  

Human TCR-β⁺ CD4^– CD8^– T Cells Can Derive from CD8⁺ T Cells and Display an Inflammatory Effector Phenotype

José C. Crispín and George C. Tsokos
J Immunol 2009 183: 4675-4681. Published online September 4, 2009; doi:10.4049/jimmunol.0901533 [Abstract] [Full Text] [PDF] Data Supplement  

Human Airway Smooth Muscle Cells from Asthmatic Individuals Have CXCL8 Hypersecretion Due to Increased NF-B p65, C/EBPβ, and RNA Polymerase II Binding to the CXCL8 Promoter

Alison E. John, Yong M. Zhu, Christopher E. Brightling, Linhua Pang, and Alan J. Knox
J Immunol 2009 183: 4682-4692. Published online September 4, 2009; doi:10.4049/jimmunol.0803832 [Abstract] [Full Text] [PDF]  

CXCR3 Mediates Renal Th1 and Th17 Immune Response in Murine Lupus Nephritis

Oliver M. Steinmetz, Jan-Eric Turner, Hans-Joachim Paust, Matthias Lindner, Anett Peters, Kirstin Heiss, Joachim Velden, Helmut Hopfer, Susanne Fehr, Thorsten Krieger, Catherine Meyer-Schwesinger, Tobias N. Meyer, Udo Helmchen, Hans-Willi Mittrücker, Rolf A. K. Stahl, and Ulf Panzer
J Immunol 2009 183: 4693-4704. Published online September 4, 2009; doi:10.4049/jimmunol.0802626 [Abstract] [Full Text] [PDF] Data Supplement  

The Role of Macrophage-Derived IL-1 in Induction and Maintenance of Angiogenesis

Yaron Carmi, Elena Voronov, Shahar Dotan, Nitza Lahat, Michal A. Rahat, Mina Fogel, Monika Huszar, Malka R. White, Charles A. Dinarello, and Ron N. Apte
J Immunol 2009 183: 4705-4714. Published online September 14, 2009; doi:10.4049/jimmunol.0901511 [Abstract] [Full Text] [PDF] Data Supplement  

Improved Survival and Reduced Vascular Permeability by Eliminating or Blocking 12/15-Lipoxygenase in Mouse Models of Acute Lung Injury (ALI)

Alexander Zarbock, Matthew R. DiStasi, Emily Smith, John M. Sanders, Gerhard Kronke, Brian L. Harry, Sibylle von Vietinghoff, Konrad Buscher, Jerry L. Nadler, and Klaus Ley
J Immunol 2009 183: 4715-4722. Published online September 14, 2009; doi:10.4049/jimmunol.0802592 [Abstract] [Full Text] [PDF]  

Aldose Reductase Inhibition Suppresses the Expression of Th2 Cytokines and Airway Inflammation in Ovalbumin-Induced Asthma in Mice

Umesh C. S. Yadav, Amarjit S. Naura, Leopoldo Aguilera-Aguirre, Kota V. Ramana, Istvan Boldogh, Sanjiv Sur, Hamid A. Boulares, and Satish K. Srivastava
J Immunol 2009 183: 4723-4732. Published online September 14, 2009; doi:10.4049/jimmunol.0901177 [Abstract] [Full Text] [PDF]  

Critical Role of TLR4 Response in the Activation of Microglia Induced by Ethanol

Sara Fernandez-Lizarbe, Maria Pascual, and Consuelo Guerri
J Immunol 2009 183: 4733-4744. Published online September 14, 2009; doi:10.4049/jimmunol.0803590 [Abstract] [Full Text] [PDF]  

Regulatory T Cells Negatively Regulate Neovasculature of Airway Remodeling via DLL4-Notch Signaling

Miao-Tzu Huang, Yang-Shia Dai, Yu-Bin Chou, Yi-Hsiu Juan, Chih-Chiang Wang, and Bor-Luen Chiang
J Immunol 2009 183: 4745-4754. Published online September 14, 2009; doi:10.4049/jimmunol.0804371 [Abstract] [Full Text] [PDF] Data Supplement  

Targeting NF-B with a Natural Triterpenoid Alleviates Skin Inflammation in a Mouse Model of Psoriasis

Honglin Wang, Tatiana Syrovets, Daniel Kess, Berthold Büchele, Heidi Hainzl, Oleg Lunov, Johannes M. Weiss, Karin Scharffetter-Kochanek, and Thomas Simmet
J Immunol 2009 183: 4755-4763. Published online September 14, 2009; doi:10.4049/jimmunol.0900521 [Abstract] [Full Text] [PDF] Data Supplement  

A Role for Complement in the Enhanced Susceptibility of Steatotic Livers to Ischemia and Reperfusion Injury

Songqing He, Carl Atkinson, Zachary Evans, Justin D. Ellett, Mark Southwood, Andrew Elvington, Kenneth D. Chavin, and Stephen Tomlinson
J Immunol 2009 183: 4764-4772. Published online September 14, 2009; doi:10.4049/jimmunol.0900550 [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Matrix Metalloproteinase (MMP)-9, but Not MMP-2, Is Involved in the Development and Progression of C Protein-Induced Myocarditis and Subsequent Dilated Cardiomyopathy

Yoh Matsumoto, Il-Kwon Park, and Kuniko Kohyama
J Immunol 2009 183: 4773-4781. Published online September 4, 2009; doi:10.4049/jimmunol.0900871 [Abstract] [Full Text] [PDF]  

Defucosylated Anti-CCR4 Monoclonal Antibody Exerts Potent ADCC against Primary ATLL Cells Mediated by Autologous Human Immune Cells in NOD/Shi-scid, IL-2R^null Mice In Vivo

Asahi Ito, Takashi Ishida, Atae Utsunomiya, Fumihiko Sato, Fumiko Mori, Hiroki Yano, Atsushi Inagaki, Susumu Suzuki, Hisashi Takino, Masaki Ri, Shigeru Kusumoto, Hirokazu Komatsu, Shinsuke Iida, Hiroshi Inagaki, and Ryuzo Ueda
J Immunol 2009 183: 4782-4791. Published online September 11, 2009; doi:10.4049/jimmunol.0900699 [Abstract] [Full Text] [PDF]  

T Cell Infiltrates in the Muscles of Patients with Dermatomyositis and Polymyositis Are Dominated by CD28^null T Cells

Andreas E. R. Fasth, Maryam Dastmalchi, Afsar Rahbar, Stina Salomonsson, Jayesh M. Pandya, Eva Lindroos, Inger Nennesmo, Karl-Johan Malmberg, Cecilia Söderberg-Nauclér, Christina Trollmo, Ingrid E. Lundberg, and Vivianne Malmström
J Immunol 2009 183: 4792-4799. Published online September 14, 2009; doi:10.4049/jimmunol.0803688 [Abstract] [Full Text] [PDF]  

Characterization of Preexisting MAGE-A3-Specific CD4⁺ T Cells in Cancer Patients and Healthy Individuals and Their Activation by Protein Vaccination

Takemasa Tsuji, Nasser K. Altorki, Gerd Ritter, Lloyd J. Old, and Sacha Gnjatic
J Immunol 2009 183: 4800-4808. Published online September 4, 2009; doi:10.4049/jimmunol.0900903 [Abstract] [Full Text] [PDF] Data Supplement  

Suppression of Ongoing T Cell-Mediated Autoimmunity by Peptide-MHC Class II Dimer Vaccination

Li Li, Zuoan Yi, Bo Wang, and Roland Tisch
J Immunol 2009 183: 4809-4816. Published online September 14, 2009; doi:10.4049/jimmunol.0901616 [Abstract] [Full Text] [PDF] Data Supplement  

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