IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2009 183: 2201-2202; doi:10.4049/jimmunol.0990058 [Full Text] [PDF] ImmunoCast  

LETTERS TO THE EDITOR:

Comment on "Decoy Receptor 3 Expression in AsPC-1 Human Pancreatic Adenocarcinoma Cells via the Phosphatidylinositol 3-Kinase-, Akt-, and NF-B-Dependent Pathway"

Wei Wang, Weimin Sun, and Lurong Zhang
J Immunol 2009 183: 2203; doi:10.4049/jimmunol.0990053 [Full Text] [PDF]  

Response to Comment on "Decoy Receptor 3 Expression in AsPC-1 Human Pancreatic Adenocarcinoma Cells via the Phosphatidylinositol 3-Kinase-, Akt-, and NF-B-Dependent Pathway"

Chia-Ron Yang
J Immunol 2009 183: 2203-2204; doi:10.4049/jimmunol.0990054 [Full Text] [PDF]  

BRIEF REVIEWS:

Secondary Lymphoid Organs: Responding to Genetic and Environmental Cues in Ontogeny and the Immune Response

Nancy H. Ruddle and Eitan M. Akirav
J Immunol 2009 183: 2205-2212; doi:10.4049/jimmunol.0804324 [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: The Chemokine Receptor CXCR3 Retains Invariant NK T Cells in the Thymus

Michael B. Drennan, Ann-Sophie Franki, Pieter Dewint, Katrien Van Beneden, Sylvie Seeuws, Serge A. van de Pavert, Emma C. Reilly, Gust Verbruggen, Thomas E. Lane, Reina E. Mebius, Dieter Deforce, and Dirk Elewaut
J Immunol 2009 183: 2213-2216. Published online July 20, 2009; doi:10.4049/jimmunol.0901213 [Abstract] [Full Text] [PDF]  

Cutting Edge: IL-7 Regulates the Peripheral Pool of Adult ROR⁺ Lymphoid Tissue Inducer Cells

Sandrine Schmutz, Nabil Bosco, Stephane Chappaz, Onur Boyman, Hans Acha-Orbea, Rhodri Ceredig, Antonius G. Rolink, and Daniela Finke
J Immunol 2009 183: 2217-2221. Published online July 27, 2009; doi:10.4049/jimmunol.0802911 [Abstract] [Full Text] [PDF] Data Supplement  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

The Cathelicidin LL-37 Activates Human Mast Cells and Is Degraded by Mast Cell Tryptase: Counter-Regulation by CXCL4

Florian Schiemann, Ernst Brandt, Roland Gross, Buko Lindner, Jessica Mittelstädt, Christian P. Sommerhoff, Jan Schulmistrat, and Frank Petersen
J Immunol 2009 183: 2223-2231. Published online July 22, 2009; doi:10.4049/jimmunol.0803587 [Abstract] [Full Text] [PDF]  

CD44 Costimulation Promotes FoxP3⁺ Regulatory T Cell Persistence and Function via Production of IL-2, IL-10, and TGF-β

Paul L. Bollyky, Ben A. Falk, S. Alice Long, Anton Preisinger, Kathy R. Braun, Rebecca P. Wu, Stephen P. Evanko, Jane H. Buckner, Thomas N. Wight, and Gerald T. Nepom
J Immunol 2009 183: 2232-2241. Published online July 27, 2009; doi:10.4049/jimmunol.0900191 [Abstract] [Full Text] [PDF] Data Supplement  

TLR-Stimulated CD34 Stem Cell-Derived Human Skin-Like and Monocyte-Derived Dendritic Cells Fail to Induce Th17 Polarization of Naive T Cells but Do Stimulate Th1 and Th17 Memory Responses

Sai Suda Duraisingham, Julia Hornig, Frances Gotch, and Steven Patterson
J Immunol 2009 183: 2242-2251. Published online July 22, 2009; doi:10.4049/jimmunol.0900474 [Abstract] [Full Text] [PDF] Data Supplement  

Vaccine-Induced Antibody Isotypes Are Skewed by Impaired CD4 T Cell and Invariant NKT Cell Effector Responses in MyD88-Deficient Mice

Onyinye I. Iweala, Donald W. Smith, Kabir S. Matharu, Isabel Sada-Ovalle, Deanna D. Nguyen, Rosemarie H. DeKruyff, Dale T. Umetsu, Samuel M. Behar, and Cathryn R. Nagler
J Immunol 2009 183: 2252-2260. Published online July 20, 2009; doi:10.4049/jimmunol.0804011 [Abstract] [Full Text] [PDF]  

Rare Development of Foxp3⁺ Thymocytes in the CD4⁺CD8⁺ Subset

Hyang Mi Lee and Chyi-Song Hsieh
J Immunol 2009 183: 2261-2266. Published online July 20, 2009; doi:10.4049/jimmunol.0901304 [Abstract] [Full Text] [PDF] Data Supplement  

Identification of DNA Methyltransferase 3a as a T Cell Receptor-Induced Regulator of Th1 and Th2 Differentiation

Christopher J. Gamper, Agoston T. Agoston, William G. Nelson, and Jonathan D. Powell
J Immunol 2009 183: 2267-2276. Published online July 22, 2009; doi:10.4049/jimmunol.0802960 [Abstract] [Full Text] [PDF]  

Transgenic Expression of Single-Chain Anti-CTLA-4 Fv on β Cells Protects Nonobese Diabetic Mice from Autoimmune Diabetes

Shing-Jia Shieh, Feng-Cheng Chou, Pei-Ning Yu, Wen-Chi Lin, Deh-Ming Chang, Steve R. Roffler, and Huey-Kang Sytwu
J Immunol 2009 183: 2277-2285. Published online July 27, 2009; doi:10.4049/jimmunol.0900679 [Abstract] [Full Text] [PDF]  

Dendritic Cells Require STAT-1 Phosphorylated at Its Transactivating Domain for the Induction of Peptide-Specific CTL

Andreas Pilz, Wolfgang Kratky, Silvia Stockinger, Olivia Simma, Ulrich Kalinke, Karen Lingnau, Alexander von Gabain, Dagmar Stoiber, Veronika Sexl, Thomas Kolbe, Thomas Rülicke, Mathias Müller, and Thomas Decker
J Immunol 2009 183: 2286-2293. Published online July 20, 2009; doi:10.4049/jimmunol.0901383 [Abstract] [Full Text] [PDF]  

Novel Generation Mycobacterial Adjuvant Based on Liposome-Encapsulated Monomycoloyl Glycerol from Mycobacterium bovis Bacillus Calmette-Guérin

Claire A. Swetman Andersen, Ida Rosenkrands, Anja W. Olsen, Pernille Nordly, Dennis Christensen, Roland Lang, Carsten Kirschning, Jessica M. Gomes, Veemal Bhowruth, David E. Minnikin, Gurdyal S. Besra, Frank Follmann, Peter Andersen, and Else Marie Agger
J Immunol 2009 183: 2294-2302. Published online July 20, 2009; doi:10.4049/jimmunol.0804091 [Abstract] [Full Text] [PDF]  

Helios Deficiency Has Minimal Impact on T Cell Development and Function

Qi Cai, Andrée Dierich, Mustapha Oulad-Abdelghani, Susan Chan, and Philippe Kastner
J Immunol 2009 183: 2303-2311. Published online July 20, 2009; doi:10.4049/jimmunol.0901407 [Abstract] [Full Text] [PDF]  

Nonredundant Roles for B Cell-Derived IL-10 in Immune Counter-Regulation

Rajat Madan, Filiz Demircik, Sangeetha Surianarayanan, Jessica L. Allen, Senad Divanovic, Aurelien Trompette, Nir Yogev, Yuanyuan Gu, Marat Khodoun, David Hildeman, Nicholas Boespflug, Mariela B. Fogolin, Lothar Gröbe, Marina Greweling, Fred D. Finkelman, Rhonda Cardin, Markus Mohrs, Werner Müller, Ari Waisman, Axel Roers, and Christopher L. Karp
J Immunol 2009 183: 2312-2320. Published online July 20, 2009; doi:10.4049/jimmunol.0900185 [Abstract] [Full Text] [PDF]  

TNFR1-Dependent Regulation of Myeloid Cell Function in Experimental Autoimmune Uveoretinitis

Ben J. E. Raveney, David A. Copland, Andrew D. Dick, and Lindsay B. Nicholson
J Immunol 2009 183: 2321-2329. Published online July 27, 2009; doi:10.4049/jimmunol.0901340 [Abstract] [Full Text] [PDF] Data Supplement  

Sphingosine 1-Phosphate Enhances Fc Receptor-Mediated Neutrophil Activation and Recruitment under Flow Conditions

Oliver Florey and Dorian O. Haskard
J Immunol 2009 183: 2330-2336. Published online July 20, 2009; doi:10.4049/jimmunol.0901019 [Abstract] [Full Text] [PDF]  

A Default Pathway of Memory CD8 T Cell Differentiation after Dendritic Cell Immunization Is Deflected by Encounter with Inflammatory Cytokines during Antigen-Driven Proliferation

Nhat-Long L. Pham, Vladimir P. Badovinac, and John T. Harty
J Immunol 2009 183: 2337-2348. Published online July 27, 2009; doi:10.4049/jimmunol.0901203 [Abstract] [Full Text] [PDF]  

Activation of FcRI on Monocytes Triggers Differentiation into Immature Dendritic Cells That Induce Autoreactive T Cell Responses

Motoyuki Tanaka, Stephan R. Krutzik, Peter A. Sieling, Delphine J. Lee, Thomas H. Rea, and Robert L. Modlin
J Immunol 2009 183: 2349-2355. Published online July 27, 2009; doi:10.4049/jimmunol.0801683 [Abstract] [Full Text] [PDF]  

Telomere Shortening and Oxidative Stress in Aged Macrophages Results in Impaired STAT5a Phosphorylation

Carlos Sebastián, Carmen Herrero, Maria Serra, Jorge Lloberas, María A. Blasco, and Antonio Celada
J Immunol 2009 183: 2356-2364. Published online July 15, 2009; doi:10.4049/jimmunol.0901131 [Abstract] [Full Text] [PDF]  

Chimeric NKG2D T Cells Require Both T Cell- and Host-Derived Cytokine Secretion and Perforin Expression to Increase Tumor Antigen Presentation and Systemic Immunity

Amorette Barber and Charles L. Sentman
J Immunol 2009 183: 2365-2372. Published online July 22, 2009; doi:10.4049/jimmunol.0900721 [Abstract] [Full Text] [PDF] Data Supplement  

Critical Roles of Translationally Controlled Tumor Protein in the Homeostasis and TCR-Mediated Proliferation of Peripheral T Cells

Peih-Shan Wu, Chia-Yu Yang, Jeffrey Jong-Young Yen, Chiang-Hung Chou, Sung Ho Chen, Chi-Kuang Leo Wang, Yein-Gei Lai, Nan-Shih Liao, and Hsin-Fang Yang-Yen
J Immunol 2009 183: 2373-2381. Published online July 15, 2009; doi:10.4049/jimmunol.0900668 [Abstract] [Full Text] [PDF] Data Supplement  

The Magnitude of CD4⁺ T Cell Recall Responses Is Controlled by the Duration of the Secondary Stimulus

Eugene V. Ravkov and Matthew A. Williams
J Immunol 2009 183: 2382-2389. Published online July 15, 2009; doi:10.4049/jimmunol.0900319 [Abstract] [Full Text] [PDF]  

Induction of Antigen-Specific Tolerance by Oral Administration of Lactococcus lactis Delivered Immunodominant DQ8-Restricted Gliadin Peptide in Sensitized Nonobese Diabetic Ab° Dq8 Transgenic Mice

Inge L. Huibregtse, Eric V. Marietta, Shadi Rashtak, Frits Koning, Pieter Rottiers, Chella S. David, Sander J. H. van Deventer, and Joseph A. Murray
J Immunol 2009 183: 2390-2396. Published online July 27, 2009; doi:10.4049/jimmunol.0802891 [Abstract] [Full Text] [PDF]  

IL-27 Abrogates Receptor Activator of NF-B Ligand-Mediated Osteoclastogenesis of Human Granulocyte-Macrophage Colony-Forming Unit Cells through STAT1-Dependent Inhibition of c-Fos

Mitsuru Furukawa, Hironari Takaishi, Jiro Takito, Masaki Yoda, Sadaoki Sakai, Tomohiro Hikata, Akihiro Hakozaki, Shinichi Uchikawa, Morio Matsumoto, Kazuhiro Chiba, Tokuhiro Kimura, Yasunori Okada, Koichi Matsuo, Hiroki Yoshida, and Yoshiaki Toyama
J Immunol 2009 183: 2397-2406. Published online July 20, 2009; doi:10.4049/jimmunol.0802091 [Abstract] [Full Text] [PDF]  

Immune Sensing of Aspergillus fumigatus Proteins, Glycolipids, and Polysaccharides and the Impact on Th Immunity and Vaccination

Silvia Bozza, Cecile Clavaud, Gloria Giovannini, Thierry Fontaine, Anne Beauvais, Jacqueline Sarfati, Carmen D'Angelo, Katia Perruccio, Pierluigi Bonifazi, Silvia Zagarella, Silvia Moretti, Francesco Bistoni, Jean-Paul Latgé, and Luigina Romani
J Immunol 2009 183: 2407-2414. Published online July 22, 2009; doi:10.4049/jimmunol.0900961 [Abstract] [Full Text] [PDF]  

HIV-1 Nef Promotes Endocytosis of Cell Surface MHC Class II Molecules via a Constitutive Pathway

Ashutosh Chaudhry, Divya Anna Verghese, Suman Ranjan Das, Shahid Jameel, Anna George, Vineeta Bal, Satyajit Mayor, and Satyajit Rath
J Immunol 2009 183: 2415-2424. Published online July 20, 2009; doi:10.4049/jimmunol.0804014 [Abstract] [Full Text] [PDF]  

Different Vaccine Vectors Delivering the Same Antigen Elicit CD8⁺ T Cell Responses with Distinct Clonotype and Epitope Specificity

Mitsuo Honda, Rui Wang, Wing-Pui Kong, Masaru Kanekiyo, Wataru Akahata, Ling Xu, Kazuhiro Matsuo, Kannan Natarajan, Howard Robinson, Tedi E. Asher, David A. Price, Daniel C. Douek, David H. Margulies, and Gary J. Nabel
J Immunol 2009 183: 2425-2434. Published online July 20, 2009; doi:10.4049/jimmunol.0900581 [Abstract] [Full Text] [PDF] Data Supplement  

IL-27 Is a Key Regulator of IL-10 and IL-17 Production by Human CD4⁺ T Cells

Gopal Murugaiyan, Akanksha Mittal, Rocio Lopez-Diego, Lisa M. Maier, David E. Anderson, and Howard L. Weiner
J Immunol 2009 183: 2435-2443. Published online July 22, 2009; doi:10.4049/jimmunol.0900568 [Abstract] [Full Text] [PDF] Data Supplement  

IL-10 Suppresses Calcium-Mediated Costimulation of Receptor Activator NF-B Signaling during Human Osteoclast Differentiation by Inhibiting TREM-2 Expression

Kyung-Hyun Park-Min, Jong-Dae Ji, Taras Antoniv, Alicia C. Reid, Randi B. Silver, Mary Beth Humphrey, Mary Nakamura, and Lionel B. Ivashkiv
J Immunol 2009 183: 2444-2455. Published online July 22, 2009; doi:10.4049/jimmunol.0804165 [Abstract] [Full Text] [PDF] Data Supplement  

Neuron-Interacting Satellite Glial Cells in Human Trigeminal Ganglia Have an APC Phenotype

Monique van Velzen, Jon D. Laman, Alex KleinJan, Angelique Poot, Albert D. M. E. Osterhaus, and Georges M. G. M. Verjans
J Immunol 2009 183: 2456-2461. Published online July 27, 2009; doi:10.4049/jimmunol.0900890 [Abstract] [Full Text] [PDF]  

Functional Modulation of Dendritic Cells and Macrophages by Japanese Encephalitis Virus through MyD88 Adaptor Molecule-Dependent and -Independent Pathways

Abi G. Aleyas, Junu A. George, Young Woo Han, M. M. Rahman, Seon Ju Kim, Sang Bae Han, Byung Sam Kim, Koanhoi Kim, and Seong Kug Eo
J Immunol 2009 183: 2462-2474. Published online July 27, 2009; doi:10.4049/jimmunol.0801952 [Abstract] [Full Text] [PDF] Data Supplement  

IDO Activates Regulatory T Cells and Blocks Their Conversion into Th17-Like T Cells

Babak Baban, Phillip R. Chandler, Madhav D. Sharma, Jeanene Pihkala, Pandelakis A. Koni, David H. Munn, and Andrew L. Mellor
J Immunol 2009 183: 2475-2483. Published online July 27, 2009; doi:10.4049/jimmunol.0900986 [Abstract] [Full Text] [PDF] Data Supplement  

Perturbation of the CD4 T Cell Compartment and Expansion of Regulatory T Cells in Autoimmune-Prone Lyn-Deficient Mice

Evelyn Tsantikos, Cathy Quilici, Kenneth W. Harder, Bo Wang, Hong-Jian Zhu, Gary P. Anderson, David M. Tarlinton, and Margaret L. Hibbs
J Immunol 2009 183: 2484-2494. Published online July 20, 2009; doi:10.4049/jimmunol.0804346 [Abstract] [Full Text] [PDF]  

Thioredoxin-Interacting Protein Regulates Hematopoietic Stem Cell Quiescence and Mobilization under Stress Conditions

Mira Jeong, Zheng-Hao Piao, Mi Sun Kim, Suk Hyung Lee, Sohyun Yun, Hu-nan Sun, Suk Ran Yoon, Jin Woong Chung, Tae-Don Kim, Jun Ho Jeon, Jiwon Lee, Hyun-Nam Kim, Je-Yong Choi, and Inpyo Choi
J Immunol 2009 183: 2495-2505. Published online July 22, 2009; doi:10.4049/jimmunol.0804221 [Abstract] [Full Text] [PDF] Data Supplement  

Dicer-Dependent MicroRNA Pathway Controls Invariant NKT Cell Development

Maya Fedeli, Anna Napolitano, Molly Pui Man Wong, Antoine Marcais, Claudia de Lalla, Francesco Colucci, Matthias Merkenschlager, Paolo Dellabona, and Giulia Casorati
J Immunol 2009 183: 2506-2512. Published online July 22, 2009; doi:10.4049/jimmunol.0901361 [Abstract] [Full Text] [PDF] Data Supplement  

CCR 7 Ligands Are Required for Development of Experimental Autoimmune Encephalomyelitis through Generating IL-23-Dependent Th17 Cells

Taku Kuwabara, Fumio Ishikawa, Takuwa Yasuda, Kentaro Aritomi, Hideki Nakano, Yuriko Tanaka, Yayoi Okada, Martin Lipp, and Terutaka Kakiuchi
J Immunol 2009 183: 2513-2521. Published online July 22, 2009; doi:10.4049/jimmunol.0800729 [Abstract] [Full Text] [PDF]  

Poly I:C-Induced Activation of NK Cells by CD8⁺ Dendritic Cells via the IPS-1 and TRIF-Dependent Pathways

Tohru Miyake, Yutaro Kumagai, Hiroki Kato, Zijin Guo, Kazufumi Matsushita, Takashi Satoh, Tatsukata Kawagoe, Himanshu Kumar, Myoung Ho Jang, Taro Kawai, Tohru Tani, Osamu Takeuchi, and Shizuo Akira
J Immunol 2009 183: 2522-2528. Published online July 27, 2009; doi:10.4049/jimmunol.0901500 [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

SCID Dogs: Similar Transplant Potential but Distinct Intra-Uterine Growth Defects and Premature Replicative Senescence Compared with SCID Mice

Katheryn Meek, Ari Jutkowitz, Lisa Allen, Jillian Glover, Erin Convery, Alisha Massa, Tom Mullaney, Bryden Stanley, Diana Rosenstein, Susan M. Bailey, Cheri Johnson, and George Georges
J Immunol 2009 183: 2529-2536. Published online July 27, 2009; doi:10.4049/jimmunol.0801406 [Abstract] [Full Text] [PDF] Data Supplement  

Antigen-Driven Evolution of B Lymphocytes in Coronary Atherosclerotic Plaques

Roberto Burioni, Filippo Canducci, Diego Saita, Mario Perotti, Nicasio Mancini, Donata De Marco, Nicola Clementi, Alaide Chieffo, Maurizio Denaro, Domenico Cianflone, Angelo A. Manfredi, Antonio Colombo, Attilio Maseri, and Massimo Clementi
J Immunol 2009 183: 2537-2544. Published online July 27, 2009; doi:10.4049/jimmunol.0901076 [Abstract] [Full Text] [PDF] Data Supplement  

The Transcription Factor RFX Protects MHC Class II Genes against Epigenetic Silencing by DNA Methylation

Queralt Seguín-Estévez, Raffaele De Palma, Michal Krawczyk, Elisa Leimgruber, Jean Villard, Capucine Picard, Augusto Tagliamacco, Gianfranco Abbate, Jack Gorski, Arcangelo Nocera, and Walter Reith
J Immunol 2009 183: 2545-2553. Published online July 20, 2009; doi:10.4049/jimmunol.0900376 [Abstract] [Full Text] [PDF]  

Structural Basis of the CD8β/MHC Class I Interaction: Focused Recognition Orients CD8β to a T Cell Proximal Position

Rui Wang, Kannan Natarajan, and David H. Margulies
J Immunol 2009 183: 2554-2564. Published online July 22, 2009; doi:10.4049/jimmunol.0901276 [Abstract] [Full Text] [PDF] Data Supplement  

A Molecular Insight into Complement Evasion by the Staphylococcal Complement Inhibitor Protein Family

Daniel Ricklin, Apostolia Tzekou, Brandon L. Garcia, Michal Hammel, William J. McWhorter, Georgia Sfyroera, You-Qiang Wu, V. Michael Holers, Andrew P. Herbert, Paul N. Barlow, Brian V. Geisbrecht, and John D. Lambris
J Immunol 2009 183: 2565-2574. Published online July 22, 2009; doi:10.4049/jimmunol.0901443 [Abstract] [Full Text] [PDF]  

Aberrant Selection and Function of Invariant NKT Cells in the Absence of AP-1 Transcription Factor Fra-2

Victoria J. Lawson, Diane Maurice, Jonathan D. Silk, Vincenzo Cerundolo, and Kathleen Weston
J Immunol 2009 183: 2575-2584. Published online July 20, 2009; doi:10.4049/jimmunol.0803577 [Abstract] [Full Text] [PDF] Data Supplement  

TLR4-Mediated Signaling Induces MMP9-Dependent Cleavage of B Cell Surface CD23

Leila Jackson, Carol T. Cady, and John C. Cambier
J Immunol 2009 183: 2585-2592. Published online July 27, 2009; doi:10.4049/jimmunol.0803660 [Abstract] [Full Text] [PDF] Data Supplement  

HOST DEFENSE:

Nontypeable Haemophilus influenzae Protein E Binds Vitronectin and Is Important for Serum Resistance

Teresia Hallström, Anna M. Blom, Peter F. Zipfel, and Kristian Riesbeck
J Immunol 2009 183: 2593-2601. Published online July 27, 2009; doi:10.4049/jimmunol.0803226 [Abstract] [Full Text] [PDF]  

Human Neutrophils Kill Streptococcus pneumoniae via Serine Proteases

Alistair J. Standish and Jeffrey N. Weiser
J Immunol 2009 183: 2602-2609. Published online July 20, 2009; doi:10.4049/jimmunol.0900688 [Abstract] [Full Text] [PDF]  

NKp44 Receptor Mediates Interaction of the Envelope Glycoproteins from the West Nile and Dengue Viruses with NK Cells

Oren Hershkovitz, Benyamin Rosental, Lior Ann Rosenberg, Martha Erika Navarro-Sanchez, Sergey Jivov, Alon Zilka, Orly Gershoni-Yahalom, Elodie Brient-Litzler, Hugues Bedouelle, Joanna W. Ho, Kerry S. Campbell, Bracha Rager-Zisman, Philippe Despres, and Angel Porgador
J Immunol 2009 183: 2610-2621. Published online July 27, 2009; doi:10.4049/jimmunol.0802806 [Abstract] [Full Text] [PDF]  

NK Cells Interfere with the Generation of Resistance against Mycoplasma Respiratory Infection following Nasal-Pulmonary Immunization

Sheetal Bodhankar, Mathew D. Woolard, Xiangle Sun, and Jerry W. Simecka
J Immunol 2009 183: 2622-2631. Published online July 22, 2009; doi:10.4049/jimmunol.0802180 [Abstract] [Full Text] [PDF]  

Neutrophil Bleaching of GFP-Expressing Staphylococci: Probing the Intraphagosomal Fate of Individual Bacteria

Jamie Schwartz, Kevin G. Leidal, Jon K. Femling, Jerrold P. Weiss, and William M. Nauseef
J Immunol 2009 183: 2632-2641. Published online July 20, 2009; doi:10.4049/jimmunol.0804110 [Abstract] [Full Text] [PDF]  

E-Prostanoid 3 Receptor Deletion Improves Pulmonary Host Defense and Protects Mice from Death in Severe Streptococcus pneumoniae Infection

David M. Aronoff, Casey Lewis, Carlos H. Serezani, Kathryn A. Eaton, Deepti Goel, John C. Phipps, Marc Peters-Golden, and Peter Mancuso
J Immunol 2009 183: 2642-2649. Published online July 27, 2009; doi:10.4049/jimmunol.0900129 [Abstract] [Full Text] [PDF]  

Leukotriene B₄ Potentiates CpG Signaling for Enhanced Cytokine Secretion by Human Leukocytes

Éric Gaudreault and Jean Gosselin
J Immunol 2009 183: 2650-2658. Published online July 20, 2009; doi:10.4049/jimmunol.0804135 [Abstract] [Full Text] [PDF]  

Quality and Vaccine Efficacy of CD4⁺ T Cell Responses Directed to Dominant and Subdominant Epitopes in ESAT-6 from Mycobacterium tuberculosis

Claus Sindbjerg Aagaard, Truc Thi Kim Thanh Hoang, Carina Vingsbo-Lundberg, Jes Dietrich, and Peter Andersen
J Immunol 2009 183: 2659-2668. Published online July 20, 2009; doi:10.4049/jimmunol.0900947 [Abstract] [Full Text] [PDF]  

TLR4- and TLR2-Mediated B Cell Responses Control the Clearance of the Bacterial Pathogen, Leptospira interrogans

Cécilia Chassin, Mathieu Picardeau, Jean-Michel Goujon, Pascale Bourhy, Nathalie Quellard, Sylvie Darche, Edgar Badell, Martine Fanton d'Andon, Nathalie Winter, Sonia Lacroix-Lamandé, Dominique Buzoni-Gatel, Alain Vandewalle, and Catherine Werts
J Immunol 2009 183: 2669-2677. Published online July 27, 2009; doi:10.4049/jimmunol.0900506 [Abstract] [Full Text] [PDF] Data Supplement  

Distinct Responses of Human Monocyte Subsets to Aspergillus fumigatus Conidia

Natalya V. Serbina, Mathew Cherny, Chao Shi, Sharon A. Bleau, Nancy H. Collins, James W. Young, and Eric G. Pamer
J Immunol 2009 183: 2678-2687. Published online July 27, 2009; doi:10.4049/jimmunol.0803398 [Abstract] [Full Text] [PDF] Data Supplement  

Intracellular Receptor for Human Host Defense Peptide LL-37 in Monocytes

Neeloffer Mookherjee, Dustin N. D. Lippert, Pamela Hamill, Reza Falsafi, Anastasia Nijnik, Jason Kindrachuk, Jelena Pistolic, Jennifer Gardy, Pegah Miri, Misbah Naseer, Leonard J. Foster, and Robert E. W. Hancock
J Immunol 2009 183: 2688-2696. Published online July 15, 2009; doi:10.4049/jimmunol.0802586 [Abstract] [Full Text] [PDF] Data Supplement  

Role of Salmonella enterica Lipopolysaccharide in Activation of Dendritic Cell Functions and Bacterial Containment

Sebastian F. Zenk, Jonathan Jantsch, and Michael Hensel
J Immunol 2009 183: 2697-2707. Published online July 22, 2009; doi:10.4049/jimmunol.0900937 [Abstract] [Full Text] [PDF] Data Supplement  

HIV-1 Envelope Induces Memory B Cell Responses That Correlate with Plasma Antibody Levels after Envelope gp120 Protein Vaccination or HIV-1 Infection

Mattia Bonsignori, M. Anthony Moody, Robert J. Parks, T. Matt Holl, Garnett Kelsoe, Charles B. Hicks, Nathan Vandergrift, Georgia D. Tomaras, and Barton F. Haynes
J Immunol 2009 183: 2708-2717. Published online July 22, 2009; doi:10.4049/jimmunol.0901068 [Abstract] [Full Text] [PDF] Data Supplement  

INFLAMMATION:

Human Neutrophils Coordinate Chemotaxis by Differential Activation of Rac1 and Rac2

Hui Zhang, Chunxiang Sun, Michael Glogauer, and Gary M. Bokoch
J Immunol 2009 183: 2718-2728. Published online July 22, 2009; doi:10.4049/jimmunol.0900849 [Abstract] [Full Text] [PDF] Data Supplement  

The Peroxisome Proliferator-Activated Receptor Agonist Pioglitazone Improves Cardiometabolic Risk and Renal Inflammation in Murine Lupus

Wenpu Zhao, Seth G. Thacker, Jeffrey B. Hodgin, Hongyu Zhang, Jeffrey H. Wang, James L. Park, Ann Randolph, Emily C. Somers, Subramaniam Pennathur, Matthias Kretzler, Frank C. Brosius, III, and Mariana J. Kaplan
J Immunol 2009 183: 2729-2740. Published online July 20, 2009; doi:10.4049/jimmunol.0804341 [Abstract] [Full Text] [PDF]  

Blocking TNF- Attenuates Aneurysm Formation in a Murine Model

Wanfen Xiong, Jason MacTaggart, Rebecca Knispel, Jennifer Worth, Yuri Persidsky, and B. Timothy Baxter
J Immunol 2009 183: 2741-2746. Published online July 20, 2009; doi:10.4049/jimmunol.0803164 [Abstract] [Full Text] [PDF]  

Caveolae Facilitate but Are Not Essential for Platelet-Activating Factor-Mediated Calcium Mobilization and Extracellular Signal-Regulated Kinase Activation

Caroline Poisson, Simon Rollin, Steeve Véronneau, Simon M. Bousquet, Jean-François Larrivée, Christian Le Gouill, Guylain Boulay, Jana Stankova, and Marek Rola-Pleszczynski
J Immunol 2009 183: 2747-2757. Published online July 20, 2009; doi:10.4049/jimmunol.0802651 [Abstract] [Full Text] [PDF]  

Concomitant Inhalation of Cigarette Smoke and Aerosolized Protein Activates Airway Dendritic Cells and Induces Allergic Airway Inflammation in a TLR-Independent Way

Lander J. Robays, Ellen A. Lanckacker, Katrien B. Moerloose, Tania Maes, Ken R. Bracke, Guy G. Brusselle, Guy F. Joos, and Karim Y. Vermaelen
J Immunol 2009 183: 2758-2766. Published online July 27, 2009; doi:10.4049/jimmunol.0802204 [Abstract] [Full Text] [PDF]  

Requirement of JNK-Mediated Phosphorylation for Translocation of Group IVA Phospholipase A₂ to Phagosomes in Human Macrophages

Javier Casas, Clara Meana, Esperanza Esquinas, Martín Valdearcos, José Pindado, Jesús Balsinde, and María A. Balboa
J Immunol 2009 183: 2767-2774. Published online July 22, 2009; doi:10.4049/jimmunol.0901530 [Abstract] [Full Text] [PDF]  

SUMOylation of Tissue Transglutaminase as Link between Oxidative Stress and Inflammation

Alessandro Luciani, Valeria Rachela Villella, Angela Vasaturo, Ida Giardino, Valeria Raia, Massimo Pettoello-Mantovani, Maria D'Apolito, Stefano Guido, Teresinha Leal, Sonia Quaratino, and Luigi Maiuri
J Immunol 2009 183: 2775-2784. Published online July 22, 2009; doi:10.4049/jimmunol.0900993 [Abstract] [Full Text] [PDF] Data Supplement  

Peptidoglycan Enhances IL-6 Production in Human Synovial Fibroblasts via TLR2 Receptor, Focal Adhesion Kinase, Akt, and AP-1- Dependent Pathway

Yung-Cheng Chiu, Ching-Yuang Lin, Chao-Ping Chen, Kui-Chou Huang, Kwok-Man Tong, Chung-Yuh Tzeng, Tu-Sheng Lee, Horng-Chaung Hsu, and Chih-Hsin Tang
J Immunol 2009 183: 2785-2792. Published online July 27, 2009; doi:10.4049/jimmunol.0802826 [Abstract] [Full Text] [PDF]  

Interactions between Innate Antiviral and Atopic Immunoinflammatory Pathways Precipitate and Sustain Asthma Exacerbations in Children

Lily S. Subrata, Joelene Bizzintino, Emilie Mamessier, Anthony Bosco, Katherine L. McKenna, Matthew E. Wikström, Jack Goldblatt, Peter D. Sly, Belinda J. Hales, Wayne R. Thomas, Ingrid A. Laing, Peter N. LeSouëf, and Patrick G. Holt
J Immunol 2009 183: 2793-2800. Published online July 20, 2009; doi:10.4049/jimmunol.0900695 [Abstract] [Full Text] [PDF] Data Supplement  

P2X₁ Ion Channels Promote Neutrophil Chemotaxis through Rho Kinase Activation

Christelle Lecut, Kim Frederix, Daniel M. Johnson, Christophe Deroanne, Marc Thiry, Céline Faccinetto, Raphaël Marée, Richard J. Evans, Paul G. A. Volders, Vincent Bours, and Cécile Oury
J Immunol 2009 183: 2801-2809. Published online July 27, 2009; doi:10.4049/jimmunol.0804007 [Abstract] [Full Text] [PDF] Data Supplement  

Regulation of Inflammatory Monocyte/Macrophage Recruitment from the Bone Marrow during Murine Cytomegalovirus Infection: Role for Type I Interferons in Localized Induction of CCR2 Ligands

Meredith J. Crane, Kirsten L. Hokeness-Antonelli, and Thais P. Salazar-Mather
J Immunol 2009 183: 2810-2817. Published online July 20, 2009; doi:10.4049/jimmunol.0900205 [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Dendritic Cell Anergy Results from Endotoxemia in Severe Malnutrition

Stephen Miles Hughes, Beatrice Amadi, Mwiya Mwiya, Hope Nkamba, Andrew Tomkins, and David Goldblatt
J Immunol 2009 183: 2818-2826. Published online July 22, 2009; doi:10.4049/jimmunol.0803518 [Abstract] [Full Text] [PDF]  

High Levels of Human Antigen-Specific CD4⁺ T Cells in Peripheral Blood Revealed by Stimulated Coexpression of CD25 and CD134 (OX40)

John J. Zaunders, Mee Ling Munier, Nabila Seddiki, Sarah Pett, Susanna Ip, Michelle Bailey, Yin Xu, Kai Brown, Wayne B. Dyer, Min Kim, Robert de Rose, Stephen J. Kent, Lele Jiang, Samuel N. Breit, Sean Emery, Anthony L. Cunningham, David A. Cooper, and Anthony D. Kelleher
J Immunol 2009 183: 2827-2836. Published online July 27, 2009; doi:10.4049/jimmunol.0803548 [Abstract] [Full Text] [PDF] Data Supplement  

A Panel of Artificial APCs Expressing Prevalent HLA Alleles Permits Generation of Cytotoxic T Cells Specific for Both Dominant and Subdominant Viral Epitopes for Adoptive Therapy

Aisha N. Hasan, Wouter J. Kollen, Deepa Trivedi, Annamalai Selvakumar, Bo Dupont, Michel Sadelain, and Richard J. O'Reilly
J Immunol 2009 183: 2837-2850. Published online July 27, 2009; doi:10.4049/jimmunol.0804178 [Abstract] [Full Text] [PDF] Data Supplement  

Two Compensatory Pathways Maintain Long-Term Stability and Diversity in CD8 T Cell Memory Repertoires

Elena N. Naumova, Jack Gorski, and Yuri N. Naumov
J Immunol 2009 183: 2851-2858. Published online July 27, 2009; doi:10.4049/jimmunol.0900162 [Abstract] [Full Text] [PDF] Data Supplement  

Suppression of Experimental Autoimmune Encephalomyelitis by Ghrelin

Michael-Mark Theil, Sachiko Miyake, Miho Mizuno, Chiharu Tomi, J. Ludovic Croxford, Hiroshi Hosoda, Julia Theil, Stephan von Hörsten, Hiroaki Yokote, Asako Chiba, Youwei Lin, Shinji Oki, Takashi Akamizu, Kenji Kangawa, and Takashi Yamamura
J Immunol 2009 183: 2859-2866. Published online July 20, 2009; doi:10.4049/jimmunol.0803362 [Abstract] [Full Text] [PDF]  

Smoking-Dependent Reprogramming of Alveolar Macrophage Polarization: Implication for Pathogenesis of Chronic Obstructive Pulmonary Disease

Renat Shaykhiev, Anja Krause, Jacqueline Salit, Yael Strulovici-Barel, Ben-Gary Harvey, Timothy P. O'Connor, and Ronald G. Crystal
J Immunol 2009 183: 2867-2883. Published online July 27, 2009; doi:10.4049/jimmunol.0900473 [Abstract] [Full Text] [PDF] Data Supplement  

CORRECTIONS:

Modulating the expression of IFN regulatory factor 8 alters the protumorigenic behavior of CD11b⁺Gr-1⁺ myeloid cells

T. J. Stewart, D. J. Liewehr, S. M. Steinberg, K. M. Greeneltch, and S. I. Abrams
J Immunol 2009 183: 2884; doi:10.4049/jimmunol.0990059 [Full Text] [PDF]  

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