IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2009 182: 5157-5158; doi:10.4049/jimmunol.0990030 [Full Text] [PDF] ImmunoCast  

LETTERS TO THE EDITOR:

Comment on "Dendritic Cells and Monocyte/Macrophages That Create the IL-6/APRIL-Rich Lymph Node Microenvironment Where Plasmablasts Mature"

Elodie Belnoue, Thomas Matthes, Claire-Anne Siegrist, and Bertrand Huard
J Immunol 2009 182: 5159; doi:10.4049/jimmunol.0990033 [Full Text] [PDF]  

Response to the Comments on "Dendritic Cells and Monocyte/Macrophages That Create the IL-6/APRIL-Rich Lymph Node Microenvironment Where Plasmablasts Mature"

Elodie Mohr, Karine Serre, and Ian MacLennan
J Immunol 2009 182: 5160; doi:10.4049/jimmunol.0990034 [Full Text] [PDF]  

Comment on "Engineering Antibody Heavy Chain CDR3 to Create a Phage Display Fab Library Rich in Antibodies That Bind Charged Carbohydrates"

Alexander H. Lucas and Donald C. Reason
J Immunol 2009 182: 5160-5161; doi:10.4049/jimmunol.0990032 [Full Text] [PDF]  

PILLARS OF IMMUNOLOGY:

Identification of the Last Cog in a Ligand-Independent Signaling Machine?

David L. Wiest
J Immunol 2009 182: 5163-5164; doi:10.4049/jimmunol.0990028 [Full Text] [PDF] [Original Pillars Article]  

Pillars Article: Analysis and Expression of a Cloned Pre-T Cell Receptor Gene. Science. 1994. 266: 1208–1212

Claude Saint-Ruf, Katharina Ungewiss, Marcus Groettrup, Ludovica Bruno, Hans Joerg Fehling, and Harald von Boehmer
J Immunol 2009 182: 5165-5169 [PDF]  

BRIEF REVIEWS:

World Malaria Day 2009: What Malaria Knows about the Immune System That Immunologists Still Do Not

Susan K. Pierce and Louis H. Miller
J Immunol 2009 182: 5171-5177; doi:10.4049/jimmunol.0804153 [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: Phosphatidylinositol 4,5-Bisphosphate Concentration at the APC Side of the Immunological Synapse Is Required for Effector T Cell Function

David Robert Fooksman, Saame Raza Shaikh, Sarah Boyle, and Michael Edidin
J Immunol 2009 182: 5179-5182; doi:10.4049/jimmunol.0801797 [Abstract] [Full Text] [PDF] Data Supplement  

Cutting Edge: Rescue of Pre-TCR but Not Mature TCR Signaling in Mice Expressing Membrane-Targeted SLP-76

Natalie A. Bezman, Rebecca G. Baker, Laurie E. Lenox, Martha S. Jordan, and Gary A. Koretzky
J Immunol 2009 182: 5183-5187; doi:10.4049/jimmunol.0802176 [Abstract] [Full Text] [PDF]  

Cutting Edge: Regulatory T Cells Do Not Require Stimulation through Their TCR to Suppress

Andrea L. Szymczak-Workman, Creg J. Workman, and Dario A. A. Vignali
J Immunol 2009 182: 5188-5192; doi:10.4049/jimmunol.0803123 [Abstract] [Full Text] [PDF] Data Supplement  

Cutting Edge: Genetic Characterization of IFN-Producing Killer Dendritic Cells

Fanny Guimont-Desrochers, Zachary John Cappello, Miguel Chagnon, Marcia McDuffie, and Sylvie Lesage
J Immunol 2009 182: 5193-5197; doi:10.4049/jimmunol.0803969 [Abstract] [Full Text] [PDF] Data Supplement  

Cutting Edge: Shift in Antigen Dependence by an Antiviral MHC Class Ib-Restricted CD8 T Cell Response during Persistent Viral Infection

Phillip A. Swanson, II, Amelia R. Hofstetter, Jarad J. Wilson, and Aron E. Lukacher
J Immunol 2009 182: 5198-5202; doi:10.4049/jimmunol.0900421 [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

CD59 Blockade Enhances Antigen-Specific CD4⁺ T Cell Responses in Humans: A New Target for Cancer Immunotherapy?

Baalasubramanian Sivasankar, M. Paula Longhi, Kathleen M. E. Gallagher, Gareth J. Betts, B. Paul Morgan, Andrew J. Godkin, and Awen M. Gallimore
J Immunol 2009 182: 5203-5207; doi:10.4049/jimmunol.0804243 [Abstract] [Full Text] [PDF]  

Ig-Like Transcript 3 Regulates Expression of Proinflammatory Cytokines and Migration of Activated T Cells

Chih-Chao Chang, Zhuoru Liu, George Vlad, Haiyan Qin, Xugang Qiao, Donna M. Mancini, Charles C. Marboe, Raffaello Cortesini, and Nicole Suciu-Foca
J Immunol 2009 182: 5208-5216; doi:10.4049/jimmunol.0804048 [Abstract] [Full Text] [PDF]  

Locally Administered TLR7 Agonists Drive Systemic Antitumor Immune Responses That Are Enhanced by Anti-CD40 Immunotherapy

Steve A. Broomfield, Robbert G. van der Most, Amy C. Prosser, Sathish Mahendran, Michael G. Tovey, Mark J. Smyth, Bruce W. S. Robinson, and Andrew J. Currie
J Immunol 2009 182: 5217-5224; doi:10.4049/jimmunol.0803826 [Abstract] [Full Text] [PDF]  

PI3K p110β Positively Regulates Lipopolysaccharide-Induced IL-12 Production in Human Macrophages and Dendritic Cells and JNK1 Plays a Novel Role

Mitsuyoshi Utsugi, Kunio Dobashi, Akihiro Ono, Tamotsu Ishizuka, Shin-ichi Matsuzaki, Takeshi Hisada, Yasuo Shimizu, Tadayoshi Kawata, Haruka Aoki, Yosuke Kamide, and Masatomo Mori
J Immunol 2009 182: 5225-5231; doi:10.4049/jimmunol.0801352 [Abstract] [Full Text] [PDF] Data Supplement  

The Role of TCR Specificity and Clonal Competition During Reconstruction of the Peripheral T Cell Pool

Catarina Leitão, António A. Freitas, and Sylvie Garcia
J Immunol 2009 182: 5232-5239; doi:10.4049/jimmunol.0804071 [Abstract] [Full Text] [PDF] Data Supplement  

PD-1 Is a Regulator of NY-ESO-1-Specific CD8⁺ T Cell Expansion in Melanoma Patients

Julien Fourcade, Pavol Kudela, Zhaojun Sun, Hongmei Shen, Stephanie R. Land, Diana Lenzner, Philippe Guillaume, Immanuel F. Luescher, Cindy Sander, Soldano Ferrone, John M. Kirkwood, and Hassane M. Zarour
J Immunol 2009 182: 5240-5249; doi:10.4049/jimmunol.0803245 [Abstract] [Full Text] [PDF]  

TRBP Homolog Interacts with Eukaryotic Initiation Factor 6 (eIF6) in Fenneropenaeus chinensis

Shuai Wang, Ning Liu, An-Jing Chen, Xiao-Fan Zhao, and Jin-Xing Wang
J Immunol 2009 182: 5250-5258; doi:10.4049/jimmunol.0802970 [Abstract] [Full Text] [PDF] Data Supplement  

Regulation of NK Cell Function by Human Granulocyte Arginase

Johanna Oberlies, Carsten Watzl, Thomas Giese, Claudia Luckner, Pascale Kropf, Ingrid Müller, Anthony D. Ho, and Markus Munder
J Immunol 2009 182: 5259-5267; doi:10.4049/jimmunol.0803523 [Abstract] [Full Text] [PDF]  

Autoantigen Immunization at Different Sites Reveals a Role for Anti-Inflammatory Effects of IFN- in Regulating Susceptibility to Experimental Autoimmune Encephalomyelitis

Silvia Pastor, Alfredo Minguela, Wentao Mi, and E. Sally Ward
J Immunol 2009 182: 5268-5275; doi:10.4049/jimmunol.0800681 [Abstract] [Full Text] [PDF]  

Liver X Receptors Control IgE Expression in B Cells

Guido Heine, Anja Dahten, Kerstin Hilt, Dennis Ernst, Milena Milovanovic, Björn Hartmann, and Margitta Worm
J Immunol 2009 182: 5276-5282; doi:10.4049/jimmunol.0801804 [Abstract] [Full Text] [PDF]  

Galectin-1 Tunes TCR Binding and Signal Transduction to Regulate CD8 Burst Size

Scot D. Liu, Tamar Tomassian, Kevin W. Bruhn, Jeff F. Miller, Françoise Poirier, and M. Carrie Miceli
J Immunol 2009 182: 5283-5295; doi:10.4049/jimmunol.0803811 [Abstract] [Full Text] [PDF]  

IL-23 Drives Pathogenic IL-17-Producing CD8⁺ T Cells

Bogoljub Ciric, Mohamed El-behi, Rosalyn Cabrera, Guang-Xian Zhang, and Abdolmohamad Rostami
J Immunol 2009 182: 5296-5305; doi:10.4049/jimmunol.0900036 [Abstract] [Full Text] [PDF] Data Supplement  

Id3 Restricts the Developmental Potential of Lineage during Thymopoiesis

Ikuko Ueda-Hayakawa, Josh Mahlios, and Yuan Zhuang
J Immunol 2009 182: 5306-5316; doi:10.4049/jimmunol.0804249 [Abstract] [Full Text] [PDF]  

A Functional IL-13 Receptor Is Expressed on Polarized Murine CD4⁺ Th17 Cells and IL-13 Signaling Attenuates Th17 Cytokine Production

Dawn C. Newcomb, Weisong Zhou, Martin L. Moore, Kasia Goleniewska, Gurjit K. K. Hershey, Jay K. Kolls, and R. Stokes Peebles, Jr.
J Immunol 2009 182: 5317-5321; doi:10.4049/jimmunol.0803868 [Abstract] [Full Text] [PDF]  

Lipopolysaccharide Potentiates Effector T Cell Accumulation into Nonlymphoid Tissues through TRIF

Jeremy P. McAleer, Robert J. Rossi, and Anthony T. Vella
J Immunol 2009 182: 5322-5330; doi:10.4049/jimmunol.0803616 [Abstract] [Full Text] [PDF]  

Experimental Autoimmune Encephalomyelitis in Lewis rats: IFN-β Acts As a Tolerogenic Adjuvant for Induction of Neuroantigen-Dependent Tolerance

Mark D. Mannie, Derek J. Abbott, and J. Lori Blanchfield
J Immunol 2009 182: 5331-5341; doi:10.4049/jimmunol.0803756 [Abstract] [Full Text] [PDF]  

Surface CD152 (CTLA-4) Expression and Signaling Dictates Longevity of CD28^null T Cells

Holger Hoff, Karin Knieke, Zulema Cabail, Heike Hirseland, George Vratsanos, Gerd-Rüdiger Burmester, Gerhard Jorch, Steven G. Nadler, Barbara Bröker, Katrin Hebel, and Monika C. Brunner-Weinzierl
J Immunol 2009 182: 5342-5351; doi:10.4049/jimmunol.0801624 [Abstract] [Full Text] [PDF]  

Protective CD8 T Cell Memory Is Impaired during Chronic CD70-Driven Costimulation

Klaas P. J. M. van Gisbergen, Ronald W. van Olffen, Josine van Beek, Koenraad F. van der Sluijs, Ramon Arens, Martijn A. Nolte, and Rene A. van Lier
J Immunol 2009 182: 5352-5362; doi:10.4049/jimmunol.0802809 [Abstract] [Full Text] [PDF]  

Pathogenic Natural Antibodies Recognizing Annexin IV Are Required to Develop Intestinal Ischemia-Reperfusion Injury

Liudmila Kulik, Sherry D. Fleming, Chantal Moratz, Jason W. Reuter, Aleksey Novikov, Kuan Chen, Kathy A. Andrews, Adam Markaryan, Richard J. Quigg, Gregg J. Silverman, George C. Tsokos, and V. Michael Holers
J Immunol 2009 182: 5363-5373; doi:10.4049/jimmunol.0803980 [Abstract] [Full Text] [PDF]  

ATLa, an Aspirin-Triggered Lipoxin A₄ Synthetic Analog, Prevents the Inflammatory and Fibrotic Effects of Bleomycin-Induced Pulmonary Fibrosis

Vanessa Martins, Samuel S. Valença, Francisco A. Farias-Filho, Raphael Molinaro, Rafael L. Simões, Tatiana P. T. Ferreira, Patrícia M. R. e Silva, Cory M. Hogaboam, Steven L. Kunkel, Iolanda M. Fierro, Claudio Canetti, and Claudia F. Benjamim
J Immunol 2009 182: 5374-5381; doi:10.4049/jimmunol.0802259 [Abstract] [Full Text] [PDF]  

Developmental Acquisition of the Lyn-CD22-SHP-1 Inhibitory Pathway Promotes B Cell Tolerance

Andrew J. Gross, Julia R. Lyandres, Anil K. Panigrahi, Eline T. Luning Prak, and Anthony L. DeFranco
J Immunol 2009 182: 5382-5392; doi:10.4049/jimmunol.0803941 [Abstract] [Full Text] [PDF] Data Supplement  

Ym1/2 Promotes Th2 Cytokine Expression by Inhibiting 12/15(S)-Lipoxygenase: Identification of a Novel Pathway for Regulating Allergic Inflammation

Yeping Cai, Rakesh K. Kumar, Jiansheng Zhou, Paul S. Foster, and Dianne C. Webb
J Immunol 2009 182: 5393-5399; doi:10.4049/jimmunol.0803874 [Abstract] [Full Text] [PDF]  

Chronic Lymphocytic Leukemia and B and T Cells Differ in Their Response to Cyclic Nucleotide Phosphodiesterase Inhibitors

John A. Meyers, Derrick W. Su, and Adam Lerner
J Immunol 2009 182: 5400-5411; doi:10.4049/jimmunol.0804255 [Abstract] [Full Text] [PDF] Data Supplement  

The Regulation of Liver Cell Survival by Complement

Maciej M. Markiewski, Robert A. DeAngelis, Christoph W. Strey, Periklis G. Foukas, Craig Gerard, Norma Gerard, Rick A. Wetsel, and John D. Lambris
J Immunol 2009 182: 5412-5418; doi:10.4049/jimmunol.0804179 [Abstract] [Full Text] [PDF]  

Galectin-2 Suppresses Contact Allergy by Inducing Apoptosis in Activated CD8⁺ T Cells

Karin Loser, Andreas Sturm, Maik Voskort, Verena Kupas, Sandra Balkow, Matteo Auriemma, Carlo Sternemann, Axel U. Dignass, Thomas A. Luger, and Stefan Beissert
J Immunol 2009 182: 5419-5429; doi:10.4049/jimmunol.0802308 [Abstract] [Full Text] [PDF]  

Target-Dependent B7-H1 Regulation Contributes to Clearance of Central Nervous Sysyem Infection and Dampens Morbidity

Timothy W. Phares, Chandran Ramakrishna, Gabriel I. Parra, Alan Epstein, Lieping Chen, Roscoe Atkinson, Stephen A. Stohlman, and Cornelia C. Bergmann
J Immunol 2009 182: 5430-5438; doi:10.4049/jimmunol.0803557 [Abstract] [Full Text] [PDF] Data Supplement  

LTβR Signaling Induces Cytokine Expression and Up-Regulates Lymphangiogenic Factors in Lymph Node Anlagen

Mark F. Vondenhoff, Mascha Greuter, Gera Goverse, Dirk Elewaut, Pieter Dewint, Carl F. Ware, Kerim Hoorweg, Georg Kraal, and Reina E. Mebius
J Immunol 2009 182: 5439-5445; doi:10.4049/jimmunol.0801165 [Abstract] [Full Text] [PDF] Data Supplement  

A Single Residue, Arginine 65, Is Critical for the Functional Interaction of Leukocyte-Associated Inhibitory Receptor-1 with Collagens

Xiaobin Tang, Sriram Narayanan, Giovanna Peruzzi, Akintomide Apara, Kannan Natarajan, David H. Margulies, John E. Coligan, and Francisco Borrego
J Immunol 2009 182: 5446-5452; doi:10.4049/jimmunol.0804052 [Abstract] [Full Text] [PDF] Data Supplement  

Expression of CD226 Antagonizes Apoptotic Cell Death in Murine Thymocytes

Liang Fang, Xinhai Zhang, Jun Miao, Fang Zhao, Kun Yang, Ran Zhuang, Hermann Bujard, Yanzhang Wei, Angang Yang, Lihua Chen, and Boquan Jin
J Immunol 2009 182: 5453-5460; doi:10.4049/jimmunol.0803090 [Abstract] [Full Text] [PDF] Data Supplement  

Conditional Gene Targeting in Mouse High Endothelial Venules

Hiroto Kawashima, Jotaro Hirakawa, Yuki Tobisawa, Minoru Fukuda, and Yumiko Saga
J Immunol 2009 182: 5461-5468; doi:10.4049/jimmunol.0802327 [Abstract] [Full Text] [PDF]  

IL-4 Is Proangiogenic in the Lung under Hypoxic Conditions

Kazuyo Yamaji-Kegan, Qingning Su, Daniel J. Angelini, and Roger A. Johns
J Immunol 2009 182: 5469-5476; doi:10.4049/jimmunol.0713347 [Abstract] [Full Text] [PDF]  

Cross-Presentation by Osteoclasts Induces FoxP3 in CD8⁺ T Cells

Jennifer R. Kiesel, Zachary S. Buchwald, and Rajeev Aurora
J Immunol 2009 182: 5477-5487; doi:10.4049/jimmunol.0803897 [Abstract] [Full Text] [PDF]  

Human Chorionic Gonadotropin Attracts Regulatory T Cells into the Fetal-Maternal Interface during Early Human Pregnancy

Anne Schumacher, Nadja Brachwitz, Sindy Sohr, Kurt Engeland, Stefanie Langwisch, Maria Dolaptchieva, Tobias Alexander, Andrei Taran, Sara Fill Malfertheiner, Serban-Dan Costa, Gerolf Zimmermann, Cindy Nitschke, Hans-Dieter Volk, Henry Alexander, Matthias Gunzer, and Ana Claudia Zenclussen
J Immunol 2009 182: 5488-5497; doi:10.4049/jimmunol.0803177 [Abstract] [Full Text] [PDF] Data Supplement  

Oncoprotein Signaling Mediates Tumor-Specific Inflammation and Enhances Tumor Progression

Jeff S. Pufnock and Jay L. Rothstein
J Immunol 2009 182: 5498-5506; doi:10.4049/jimmunol.0801284 [Abstract] [Full Text] [PDF]  

Bone Marrow-Derived Mast Cells Accumulate in the Central Nervous System During Inflammation but Are Dispensable for Experimental Autoimmune Encephalomyelitis Pathogenesis

Jami L. Bennett, Marie-Renée Blanchet, Linlin Zhao, Lori Zbytnuik, Frann Antignano, Matthew Gold, Paul Kubes, and Kelly M. McNagny
J Immunol 2009 182: 5507-5514; doi:10.4049/jimmunol.0801485 [Abstract] [Full Text] [PDF]  

Impaired CD4 and CD8 Effector Function and Decreased Memory T Cell Populations in ICOS-Deficient Patients

Naomi Takahashi, Kenji Matsumoto, Hirohisa Saito, Toshihiro Nanki, Nobuyuki Miyasaka, Tetsuji Kobata, Miyuki Azuma, Sang-Kyou Lee, Shuki Mizutani, and Tomohiro Morio
J Immunol 2009 182: 5515-5527; doi:10.4049/jimmunol.0803256 [Abstract] [Full Text] [PDF] Data Supplement  

Impact of Intrinsic Cooperative Thermodynamics of Peptide-MHC Complexes on Antiviral Activity of HIV-Specific CTL

Chihiro Motozono, Saeko Yanaka, Kouhei Tsumoto, Masafumi Takiguchi, and Takamasa Ueno
J Immunol 2009 182: 5528-5536; doi:10.4049/jimmunol.0803471 [Abstract] [Full Text] [PDF]  

An Anti-Vascular Endothelial Growth Factor Receptor 2/Fetal Liver Kinase-1 Listeria monocytogenes Anti-Angiogenesis Cancer Vaccine for the Treatment of Primary and Metastatic Her-2/neu⁺ Breast Tumors in a Mouse Model

Matthew M. Seavey, Paulo C. Maciag, Nada Al-Rawi, Duane Sewell, and Yvonne Paterson
J Immunol 2009 182: 5537-5546; doi:10.4049/jimmunol.0803742 [Abstract] [Full Text] [PDF] Data Supplement  

TLR Agonists Prevent the Establishment of Allogeneic Hematopoietic Chimerism in Mice Treated with Costimulation Blockade

David M. Miller, Thomas B. Thornley, Todd Pearson, Annie J. Kruger, Masahiro Yamazaki, Leonard D. Shultz, Raymond M. Welsh, Michael A. Brehm, Aldo A. Rossini, and Dale L. Greiner
J Immunol 2009 182: 5547-5559; doi:10.4049/jimmunol.0802077 [Abstract] [Full Text] [PDF]  

Rapid Up-Regulation and Granule-Independent Transport of Perforin to the Immunological Synapse Define a Novel Mechanism of Antigen-Specific CD8⁺ T Cell Cytotoxic Activity

George Makedonas, Pinaki P. Banerjee, Rahul Pandey, Adam R. Hersperger, Keri B. Sanborn, Gareth A. D. Hardy, Jordan S. Orange, and Michael R. Betts
J Immunol 2009 182: 5560-5569; doi:10.4049/jimmunol.0803945 [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Molecular Dissection of Antibody Responses against Pneumococcal Surface Protein A: Evidence for Diverse D_H-Less Heavy Chain Gene Usage and Avidity Maturation

Soma Rohatgi, Debjani Dutta, Suhail Tahir, and Devinder Sehgal
J Immunol 2009 182: 5570-5585; doi:10.4049/jimmunol.0803254 [Abstract] [Full Text] [PDF] Data Supplement  

Assembled DJβ Complexes Influence TCRβ Chain Selection and Peripheral Vβ Repertoire

Andrea C. Carpenter, Katherine S. Yang-Iott, Linda H. Chao, Beth Nuskey, Scott Whitlow, Frederick W. Alt, and Craig H. Bassing
J Immunol 2009 182: 5586-5595; doi:10.4049/jimmunol.0803270 [Abstract] [Full Text] [PDF]  

The Essential Role of LAT in Thymocyte Development during Transition from the Double-Positive to Single-Positive Stage

Shudan Shen, Minghua Zhu, Jasmine Lau, Mariana Chuck, and Weiguo Zhang
J Immunol 2009 182: 5596-5604; doi:10.4049/jimmunol.0803170 [Abstract] [Full Text] [PDF]  

Patterns of Receptor Revision in the Immunoglobulin Heavy Chains of a Teleost Fish

Miles D. Lange, Geoffrey C. Waldbieser, and Craig J. Lobb
J Immunol 2009 182: 5605-5622; doi:10.4049/jimmunol.0801013 [Abstract] [Full Text] [PDF]  

IMMUNOGENETICS:

IL-6 Modulates CD5 Expression in B Cells from Patients with Lupus by Regulating DNA Methylation

Soizic Garaud, Christelle Le Dantec, Sandrine Jousse-Joulin, Catherine Hanrotel-Saliou, Alain Saraux, Rizgar A. Mageed, Pierre Youinou, and Yves Renaudineau
J Immunol 2009 182: 5623-5632; doi:10.4049/jimmunol.0802412 [Abstract] [Full Text] [PDF] Data Supplement  

Direct Hematological Toxicity and Illegitimate Chromosomal Recombination Caused by the Systemic Activation of CreER^T2

Atsuko Yoshioka Higashi, Tomokatsu Ikawa, Masamichi Muramatsu, Aris N. Economides, Akira Niwa, Tomohiko Okuda, Andrew J. Murphy, Jose Rojas, Toshio Heike, Tatsutoshi Nakahata, Hiroshi Kawamoto, Toru Kita, and Motoko Yanagita
J Immunol 2009 182: 5633-5640; doi:10.4049/jimmunol.0802413 [Abstract] [Full Text] [PDF] Data Supplement  

HOST DEFENSE:

Transcriptome Profiling and Functional Analyses of the Zebrafish Embryonic Innate Immune Response to Salmonella Infection

Oliver W. Stockhammer, Anna Zakrzewska, Zoltán Hegedûs, Herman P. Spaink, and Annemarie H. Meijer
J Immunol 2009 182: 5641-5653; doi:10.4049/jimmunol.0900082 [Abstract] [Full Text] [PDF] Data Supplement  

Phagocytosis in Macrophages Lacking Cbl Reveals an Unsuspected Role for Fc Receptor Signaling and Actin Assembly in Target Binding

Benjamin M. Dale, Daniel Traum, Hediye Erdjument-Bromage, Paul Tempst, and Steven Greenberg
J Immunol 2009 182: 5654-5662; doi:10.4049/jimmunol.0803942 [Abstract] [Full Text] [PDF] Data Supplement  

Gastrointestinal Nematode Infection Exacerbates Malaria-Induced Liver Pathology

Helena Helmby
J Immunol 2009 182: 5663-5671; doi:10.4049/jimmunol.0803790 [Abstract] [Full Text] [PDF]  

A Proviral Role for CpG in Cytomegalovirus Infection

Ann-Charlotte Iversen, Bjørg Steinkjer, Nadra Nilsen, Janne Bohnhorst, Siv Helen Moen, Randi Vik, Phil Stephens, David W. Thomas, Chris A. Benedict, and Terje Espevik
J Immunol 2009 182: 5672-5681; doi:10.4049/jimmunol.0801268 [Abstract] [Full Text] [PDF]  

Actin and RIG-I/MAVS Signaling Components Translocate to Mitochondria upon Influenza A Virus Infection of Human Primary Macrophages

Tiina Öhman, Johanna Rintahaka, Nisse Kalkkinen, Sampsa Matikainen, and Tuula A. Nyman
J Immunol 2009 182: 5682-5692; doi:10.4049/jimmunol.0803093 [Abstract] [Full Text] [PDF]  

Mechanism Regulating Reactive Oxygen Species in Tumor-Induced Myeloid-Derived Suppressor Cells

Cesar A. Corzo, Matthew J. Cotter, Pingyan Cheng, Fendong Cheng, Sergei Kusmartsev, Eduardo Sotomayor, Tapan Padhya, Thomas V. McCaffrey, Judith C. McCaffrey, and Dmitry I. Gabrilovich
J Immunol 2009 182: 5693-5701; doi:10.4049/jimmunol.0900092 [Abstract] [Full Text] [PDF]  

IL-7 Receptor Expression Provides the Potential for Long-Term Survival of Both CD62L^high Central Memory T Cells and Th1 Effector Cells during Leishmania major Infection

Sara L. Colpitts, Nicole M. Dalton, and Phillip Scott
J Immunol 2009 182: 5702-5711; doi:10.4049/jimmunol.0803450 [Abstract] [Full Text] [PDF]  

The Innate Immune Response Affects the Development of the Autoimmune Response in Theiler’s Virus-Induced Demyelinating Disease

Julie K. Olson and Stephen D. Miller
J Immunol 2009 182: 5712-5722; doi:10.4049/jimmunol.0801940 [Abstract] [Full Text] [PDF] Data Supplement  

The Avidity and Lytic Efficiency of the CTL Response to HTLV-1

Tarek Kattan, Aidan MacNamara, Aileen G. Rowan, Hirohisa Nose, Angelina J. Mosley, Yuetsu Tanaka, Graham P. Taylor, Becca Asquith, and Charles R. M. Bangham
J Immunol 2009 182: 5723-5729; doi:10.4049/jimmunol.0900069 [Abstract] [Full Text] [PDF]  

Pertussis Toxin Signals through the TCR to Initiate Cross-Desensitization of the Chemokine Receptor CXCR4

Olivia D. Schneider, Alison A. Weiss, and William E. Miller
J Immunol 2009 182: 5730-5739; doi:10.4049/jimmunol.0803114 [Abstract] [Full Text] [PDF]  

INFLAMMATION:

A Role for Bid in Eosinophil Apoptosis and in Allergic Airway Reaction

Marielle Maret, Claude Ruffié, Séverine Létuvé, Aurélie Phelep, Olivier Thibaudeau, Joëlle Marchal, Marina Pretolani, and Anne Druilhe
J Immunol 2009 182: 5740-5747; doi:10.4049/jimmunol.0800864 [Abstract] [Full Text] [PDF]  

IL-27 Blocks RORc Expression to Inhibit Lineage Commitment of Th17 Cells

Caroline Diveu, Mandy J. McGeachy, Katia Boniface, Jason S. Stumhofer, Manjiri Sathe, Barbara Joyce-Shaikh, Yi Chen, Cristina M. Tato, Terrill K. McClanahan, René de Waal Malefyt, Christopher A. Hunter, Daniel J. Cua, and Robert A. Kastelein
J Immunol 2009 182: 5748-5756; doi:10.4049/jimmunol.0801162 [Abstract] [Full Text] [PDF]  

NF-B p50 Regulates C/EBP Expression and Inflammatory Cytokine-Induced Neutrophil Production

Dehua Wang, Ido Paz-Priel, and Alan D. Friedman
J Immunol 2009 182: 5757-5762; doi:10.4049/jimmunol.0803861 [Abstract] [Full Text] [PDF]  

Differential Regulation of Foxp3 and IL-17 Expression in CD4 T Helper Cells by IRAK-1

Urmila Maitra, Sarah Davis, Christopher M. Reilly, and Liwu Li
J Immunol 2009 182: 5763-5769; doi:10.4049/jimmunol.0900124 [Abstract] [Full Text] [PDF]  

₂-Macroglobulin Capture Allows Detection of Mast Cell Chymase in Serum and Creates a Reservoir of Angiotensin II-Generating Activity

Wilfred W. Raymond, Sharon Su, Anastasia Makarova, Todd M. Wilson, Melody C. Carter, Dean D. Metcalfe, and George H. Caughey
J Immunol 2009 182: 5770-5777; doi:10.4049/jimmunol.0900127 [Abstract] [Full Text] [PDF]  

Amyloid β Interaction with Receptor for Advanced Glycation End Products Up-Regulates Brain Endothelial CCR5 Expression and Promotes T Cells Crossing the Blood-Brain Barrier

Man Li, De-Shu Shang, Wei-Dong Zhao, Li Tian, Bo Li, Wen-Gang Fang, Li Zhu, Shu-Mei Man, and Yu-Hua Chen
J Immunol 2009 182: 5778-5788; doi:10.4049/jimmunol.0803013 [Abstract] [Full Text] [PDF] Data Supplement  

Inflammation Recapitulates the Ontogeny of Lymphoid Stromal Cells

Lucie Peduto, Sophie Dulauroy, Matthias Lochner, Gerald F. Späth, Miguel A. Morales, Ana Cumano, and Gérard Eberl
J Immunol 2009 182: 5789-5799; doi:10.4049/jimmunol.0803974 [Abstract] [Full Text] [PDF] Data Supplement  

HMGB1 Is Phosphorylated by Classical Protein Kinase C and Is Secreted by a Calcium-Dependent Mechanism

Young Joo Oh, Ju Ho Youn, Yeounjung Ji, Sang Eun Lee, Kook Jin Lim, Ji Eun Choi, and Jeon-Soo Shin
J Immunol 2009 182: 5800-5809; doi:10.4049/jimmunol.0801873 [Abstract] [Full Text] [PDF]  

An Atypical Protein Kinase C (PKC) Plays a Critical Role in Lipopolysaccharide-Activated NF-B in Human Peripheral Blood Monocytes and Macrophages

XueSong Huang, Ling-Yu Chen, Astrid M. Doerner, Warren W. Pan, Laura Smith, Shuang Huang, Thomas J. Papadimos, and Zhixing K. Pan
J Immunol 2009 182: 5810-5815; doi:10.4049/jimmunol.0804073 [Abstract] [Full Text] [PDF]  

Deletion of PPAR in Alveolar Macrophages Is Associated with a Th-1 Pulmonary Inflammatory Response

Anagha Malur, Almedia J. Mccoy, Sergio Arce, Barbara P. Barna, Mani S. Kavuru, Achut G. Malur, and Mary Jane Thomassen
J Immunol 2009 182: 5816-5822; doi:10.4049/jimmunol.0803504 [Abstract] [Full Text] [PDF]  

The Major Outer Membrane Protein of a Periodontopathogen Induces IFN-β and IFN-Stimulated Genes in Monocytes via Lipid Raft and TANK-Binding Kinase 1/IFN Regulatory Factor-3

Sung-Hoon Lee, Joong Su Kim, Hye-Kyoung Jun, Hae-Ri Lee, Daesil Lee, and Bong-Kyu Choi
J Immunol 2009 182: 5823-5835; doi:10.4049/jimmunol.0802765 [Abstract] [Full Text] [PDF]  

Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis

Leslie van der Fits, Sabine Mourits, Jane S. A. Voerman, Marius Kant, Louis Boon, Jon D. Laman, Ferry Cornelissen, Anne-Marie Mus, Edwin Florencia, Errol P. Prens, and Erik Lubberts
J Immunol 2009 182: 5836-5845; doi:10.4049/jimmunol.0802999 [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Luteinizing Hormone-Releasing Hormone Enhances T Cell Recovery following Allogeneic Bone Marrow Transplantation

Gabrielle L. Goldberg, Christopher G. King, Rebecca A. Nejat, David Y. Suh, Odette M. Smith, Jamison C. Bretz, Robert M. Samstein, Jarrod A. Dudakov, Ann P. Chidgey, Selina Chen-Kiang, Richard L. Boyd, and Marcel R. M. van den Brink
J Immunol 2009 182: 5846-5854; doi:10.4049/jimmunol.0801458 [Abstract] [Full Text] [PDF]  

Selective Oxidation of DNA Topoisomerase 1 Induces Systemic Sclerosis in the Mouse

Amélie Servettaz, Claire Goulvestre, Niloufar Kavian, Carole Nicco, Philippe Guilpain, Christiane Chéreau, Vincent Vuiblet, Loïc Guillevin, Luc Mouthon, Bernard Weill, and Frédéric Batteux
J Immunol 2009 182: 5855-5864; doi:10.4049/jimmunol.0803705 [Abstract] [Full Text] [PDF] Data Supplement  

Matrix Metalloproteinase-1 Is Regulated in Tuberculosis by a p38 MAPK-Dependent, p-Aminosalicylic Acid-Sensitive Signaling Cascade

Lucinda Rand, Justin A. Green, Luísa Saraiva, Jon S. Friedland, and Paul T. G. Elkington
J Immunol 2009 182: 5865-5872; doi:10.4049/jimmunol.0801935 [Abstract] [Full Text] [PDF]  

Tumor Regression following DNA Vaccination and Regulatory T Cell Depletion in neu Transgenic Mice Leads to an Increased Risk for Autoimmunity

Jennifer B. Jacob, Yi-chi M. Kong, Ilke Nalbantoglu, Daniel P. Snower, and Wei-Zen Wei
J Immunol 2009 182: 5873-5881; doi:10.4049/jimmunol.0804074 [Abstract] [Full Text] [PDF] Data Supplement  

CORRECTIONS:

Characterization of early stages of human B cell development by gene expression profiling

M. E. Hystad, J. H. Myklebust, T. H. Bø, E. A. Sivertsen, E. Rian, L. Forfang, E. Munthe, A. Rosenwald, M. Chiorazzi, I. Jonassen, L. Staudt, and E. B. Smeland
J Immunol 2009 182: 5882; doi:10.4049/jimmunol.0990031 [Full Text] [PDF]  

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