IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2009 182: 4493-4494; doi:10.4049/jimmunol.0990021 [Full Text] [PDF] ImmunoCast  

LETTERS TO THE EDITOR:

Comment on "Reassessment of the Role of Mut S Homolog 5 in Ig Class Switch Recombination Shows Lack of Involvement in cis- and trans-Switching"

Hideharu Sekine, Ricardo C. Ferreira, Qiang Pan-Hammarström, Lennart Hammarström, Gary S. Gilkeson, and Timothy W. Behrens
J Immunol 2009 182: 4495-4496; doi:10.4049/jimmunol.0990026 [Full Text] [PDF]  

Response to Comment on "Reassessment of the Role of Mut S Homolog 5 in Ig Class Switch Recombination Shows Lack of Involvement in cis- and trans-Switching"

Jeroen E. J. Guikema, Carol E. Schrader, Stephen P. Baker, Winfried Edelmann, and Janet Stavnezer
J Immunol 2009 182: 4496-4497; doi:10.4049/jimmunol.0990027 [Full Text] [PDF]  

Comment on "Experimental Extracorporeal Photopheresis Inhibits the Sensitization and Effector Phases of Contact Hypersensitivity via Two Mechanisms: Generation of IL-10 and Induction of Regulatory T Cells"

Roberta Rizzo, Marina Stignani, Loredana Melchiorri, and Olavio R. Baricordi
J Immunol 2009 182: 4497; doi:10.4049/jimmunol.0990025 [Full Text] [PDF]  

BRIEF REVIEWS:

Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer

Suzanne Ostrand-Rosenberg and Pratima Sinha
J Immunol 2009 182: 4499-4506; doi:10.4049/jimmunol.0802740 [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: Lung Mucosal Th17-Mediated Responses Induce Polymeric Ig Receptor Expression by the Airway Epithelium and Elevate Secretory IgA Levels

Zeina Jaffar, Maria E. Ferrini, Lou A. Herritt, and Kevan Roberts
J Immunol 2009 182: 4507-4511; doi:10.4049/jimmunol.0900237 [Abstract] [Full Text] [PDF] Data Supplement  

Cutting Edge: IL-2 Immune Complexes As a Therapy for Persistent Virus Infection

Michael J. Molloy, Weijun Zhang, and Edward J. Usherwood
J Immunol 2009 182: 4512-4515; doi:10.4049/jimmunol.0804175 [Abstract] [Full Text] [PDF] Data Supplement  

Cutting Edge: A Critical Role of B and T Lymphocyte Attenuator in Peripheral T Cell Tolerance Induction

Xikui Liu, Maria Alexiou, Natalia Martin-Orozco, Yeonseok Chung, Roza I. Nurieva, Li Ma, Qiang Tian, George Kollias, Sijie Lu, Daniel Graf, and Chen Dong
J Immunol 2009 182: 4516-4520; doi:10.4049/jimmunol.0803161 [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

IL-22-Dependent Attenuation of T Cell-Dependent (ConA) Hepatitis in Herpes Virus Entry Mediator Deficiency

Christian Wahl, Ursula Maria Wegenka, Frank Leithäuser, Reinhold Schirmbeck, and Jörg Reimann
J Immunol 2009 182: 4521-4528; doi:10.4049/jimmunol.0802810 [Abstract] [Full Text] [PDF]  

Early Hematopoietic Zinc Finger Protein Prevents Tumor Cell Recognition by Natural Killer Cells

Rosanna La Rocca, Mariateresa Fulciniti, Tadepally Lakshmikanth, Maria Mesuraca, Talib Hassan Ali, Valerio Mazzei, Nicola Amodio, Lucio Catalano, Bruno Rotoli, Ouathek Ouerfelli, Michele Grieco, Elio Gulletta, Heather M. Bond, Giovanni Morrone, Soldano Ferrone, and Ennio Carbone
J Immunol 2009 182: 4529-4537; doi:10.4049/jimmunol.0802109 [Abstract] [Full Text] [PDF]  

Induction of Tumor Cell Apoptosis or Necrosis by Conditional Expression of Cell Death Proteins: Analysis of Cell Death Pathways and In Vitro Immune Stimulatory Potential

Christine Lohmann, Andreas Muschaweckh, Susanne Kirschnek, Luise Jennen, Hermann Wagner, and Georg Häcker
J Immunol 2009 182: 4538-4546; doi:10.4049/jimmunol.0803989 [Abstract] [Full Text] [PDF] Data Supplement  

FcRIIA and FcRIIIB Mediate Nuclear Factor Activation through Separate Signaling Pathways in Human Neutrophils

Erick García-García, Georgina Nieto-Castañeda, Melissa Ruiz-Saldaña, Nancy Mora, and Carlos Rosales
J Immunol 2009 182: 4547-4556; doi:10.4049/jimmunol.0801468 [Abstract] [Full Text] [PDF]  

Costimulation of Dendritic Epidermal T Cells by a New NKG2D Ligand Expressed Specifically in the Skin

Michael I. Whang, Nadia Guerra, and David H. Raulet
J Immunol 2009 182: 4557-4564; doi:10.4049/jimmunol.0802439 [Abstract] [Full Text] [PDF]  

A Single-Chain H-2D^b Molecule Presenting an Influenza Virus Nucleoprotein Epitope Shows Enhanced Ability at Stimulating CD8⁺ T Cell Responses In Vivo

Michael J. Palmowski, Mathew Parker, Kaushik Choudhuri, Christopher Chiu, Margaret F. C. Callan, P. Anton van der Merwe, Vincenzo Cerundolo, and Keith G. Gould
J Immunol 2009 182: 4565-4571; doi:10.4049/jimmunol.0803893 [Abstract] [Full Text] [PDF]  

NK Cell Responsiveness Is Tuned Commensurate with the Number of Inhibitory Receptors for Self-MHC Class I: The Rheostat Model

Nathalie T. Joncker, Nadine C. Fernandez, Emmanuel Treiner, Eric Vivier, and David H. Raulet
J Immunol 2009 182: 4572-4580; doi:10.4049/jimmunol.0803900 [Abstract] [Full Text] [PDF] Data Supplement  

Thymic OX40 Expression Discriminates Cells Undergoing Strong Responses to Selection Ligands

Mark Klinger, Joong Kyu Kim, Stephen A. Chmura, Andrea Barczak, David J. Erle, and Nigel Killeen
J Immunol 2009 182: 4581-4589; doi:10.4049/jimmunol.0900010 [Abstract] [Full Text] [PDF] Data Supplement  

Early Infection Termination Affects Number of CD8⁺ Memory T Cells and Protective Capacities in Listeria monocytogenes-Infected Mice upon Rechallenge

Kuo-En Tseng, Cheng-Yu Chung, Weng Siong H’ng, and Shih-Lien Wang
J Immunol 2009 182: 4590-4600; doi:10.4049/jimmunol.0801125 [Abstract] [Full Text] [PDF]  

The Amino Acid Sequences Flanking an Antigenic Determinant Can Strongly Affect MHC Class I Cross-Presentation without Altering Direct Presentation

Xueying Ma, Amparo Serna, Ren-Huan Xu, and Luis J. Sigal
J Immunol 2009 182: 4601-4607; doi:10.4049/jimmunol.0803806 [Abstract] [Full Text] [PDF]  

Rabbit Polyclonal Mouse Antithymocyte Globulin Administration Alters Dendritic Cell Profile and Function in NOD Mice to Suppress Diabetogenic Responses

Yanfei Huang, Matthew Parker, Changqing Xia, Ruihua Peng, Clive Wasserfall, Tracy Clarke, Lizhen Wu, Tayseer Chowdhry, Martha Campbell-Thompson, John Williams, Michael Clare-Salzler, Mark A. Atkinson, and Karl L. Womer
J Immunol 2009 182: 4608-4615; doi:10.4049/jimmunol.0713269 [Abstract] [Full Text] [PDF]  

The A_2B Adenosine Receptor Impairs the Maturation and Immunogenicity of Dendritic Cells

Jeffrey M. Wilson, William G. Ross, Oma N. Agbai, Renea Frazier, Robert A. Figler, Jayson Rieger, Joel Linden, and Peter B. Ernst
J Immunol 2009 182: 4616-4623; doi:10.4049/jimmunol.0801279 [Abstract] [Full Text] [PDF] Data Supplement  

Calcitriol Suppresses Antiretinal Autoimmunity through Inhibitory Effects on the Th17 Effector Response

Jun Tang, Ru Zhou, Dror Luger, Wei Zhu, Phyllis B. Silver, Rafael S. Grajewski, Shao-Bo Su, Chi-Chao Chan, Luciano Adorini, and Rachel R. Caspi
J Immunol 2009 182: 4624-4632; doi:10.4049/jimmunol.0801543 [Abstract] [Full Text] [PDF]  

Activin A Promotes the TGF-β-Induced Conversion of CD4⁺CD25^– T Cells into Foxp3⁺ Induced Regulatory T Cells

Samuel Huber, Felix R. Stahl, Jörg Schrader, Stefan Lüth, Katrin Presser, Antonella Carambia, Richard A. Flavell, Sabine Werner, Manfred Blessing, Johannes Herkel, and Christoph Schramm
J Immunol 2009 182: 4633-4640; doi:10.4049/jimmunol.0803143 [Abstract] [Full Text] [PDF] Data Supplement  

Selective Requirement for c-Myc at an Early Stage of V14i NKT Cell Development

Marcin P. Mycko, Isabel Ferrero, Anne Wilson, Wei Jiang, Teresa Bianchi, Andreas Trumpp, and H. Robson MacDonald
J Immunol 2009 182: 4641-4648; doi:10.4049/jimmunol.0803394 [Abstract] [Full Text] [PDF]  

A Positive Feedback Loop of IL-21 Signaling Provoked by Homeostatic CD4⁺CD25^– T Cell Expansion Is Essential for the Development of Arthritis in Autoimmune K/BxN Mice

Eunkyeong Jang, Sin-Hye Cho, Hyunjoo Park, Doo-Jin Paik, Jung Mogg Kim, and Jeehee Youn
J Immunol 2009 182: 4649-4656; doi:10.4049/jimmunol.0804350 [Abstract] [Full Text] [PDF]  

Langerhans Cells Are Not Required for the CD8 T Cell Response to Epidermal Self-Antigens

Laura S. Bursch, Benjamin E. Rich, and Kristin A. Hogquist
J Immunol 2009 182: 4657-4664; doi:10.4049/jimmunol.0803656 [Abstract] [Full Text] [PDF]  

Maintenance of Peripheral Tolerance through Controlled Tissue Homing of Antigen-Specific T Cells in K14-mOVA Mice

Teresa Bianchi, Laura B. Pincus, Marc-André Wurbel, Benjamin E. Rich, Thomas S. Kupper, Robert C. Fuhlbrigge, and Marianne Boes
J Immunol 2009 182: 4665-4674; doi:10.4049/jimmunol.0803628 [Abstract] [Full Text] [PDF] Data Supplement  

Tumor Recognition and Self-Recognition Induce Distinct Transcriptional Profiles in Antigen-Specific CD4 T Cells

Derese Getnet, Charles H. Maris, Edward L. Hipkiss, Joseph F. Grosso, Timothy J. Harris, Hung-Rong Yen, Tullia C. Bruno, Satoshi Wada, Adam Adler, Robert W. Georgantas, Chunfa Jie, Monica V. Goldberg, Drew M. Pardoll, and Charles G. Drake
J Immunol 2009 182: 4675-4685; doi:10.4049/jimmunol.0803400 [Abstract] [Full Text] [PDF] Data Supplement  

Inducible MHC Class II Expression by Mast Cells Supports Effector and Regulatory T Cell Activation

Taku Kambayashi, Eric J. Allenspach, John T. Chang, Tao Zou, Jonathan E. Shoag, Steven L. Reiner, Andrew J. Caton, and Gary A. Koretzky
J Immunol 2009 182: 4686-4695; doi:10.4049/jimmunol.0803180 [Abstract] [Full Text] [PDF]  

Inositol 1,4,5-Trisphosphate 3-Kinase B Is a Negative Regulator of BCR Signaling That Controls B Cell Selection and Tolerance Induction

Andrew T. Miller, Daniel R. Beisner, Daorong Liu, and Michael P. Cooke
J Immunol 2009 182: 4696-4704; doi:10.4049/jimmunol.0802850 [Abstract] [Full Text] [PDF]  

Nerve Growth Factor and Neurotrophin-3 Mediate Survival of Pulmonary Plasma Cells during the Allergic Airway Inflammation

Melanie Abram, Michael Wegmann, Verena Fokuhl, Sanchaita Sonar, Elke Olga Luger, Sebastian Kerzel, Andreas Radbruch, Harald Renz, and Michael Zemlin
J Immunol 2009 182: 4705-4712; doi:10.4049/jimmunol.0802814 [Abstract] [Full Text] [PDF] Data Supplement  

Superantigen- and TLR-Dependent Activation of Tonsillar B Cells after Receptor-Mediated Endocytosis

Johan Jendholm, Matthias Mörgelin, Maria Laura A. Perez Vidakovics, Michael Carlsson, Hakon Leffler, Lars-Olaf Cardell, and Kristian Riesbeck
J Immunol 2009 182: 4713-4720; doi:10.4049/jimmunol.0803032 [Abstract] [Full Text] [PDF]  

The Generation of Influenza-Specific Humoral Responses Is Impaired in ST6Gal I-Deficient Mice

Junwei Zeng, Hye Mee Joo, Bheemreddy Rajini, Jens P. Wrammert, Mark Y. Sangster, and Thandi M. Onami
J Immunol 2009 182: 4721-4727; doi:10.4049/jimmunol.0802833 [Abstract] [Full Text] [PDF]  

Adaptive Immune Response in JAM-C-Deficient Mice: Normal Initiation but Reduced IgG Memory

Claudia Zimmerli, Boris P. L. Lee, Gaby Palmer, Cem Gabay, Ralf Adams, Michel Aurrand-Lions, and Beat A. Imhof
J Immunol 2009 182: 4728-4736; doi:10.4049/jimmunol.0803892 [Abstract] [Full Text] [PDF]  

IL-9 Promotes IL-13-Dependent Paneth Cell Hyperplasia and Up-Regulation of Innate Immunity Mediators in Intestinal Mucosa

Valérie Steenwinckel, Jamila Louahed, Muriel M. Lemaire, Caroline Sommereyns, Guy Warnier, Andrew McKenzie, Frank Brombacher, Jacques Van Snick, and Jean-Christophe Renauld
J Immunol 2009 182: 4737-4743; doi:10.4049/jimmunol.0801941 [Abstract] [Full Text] [PDF]  

Statins Impair CD1d-Mediated Antigen Presentation through the Inhibition of Prenylation

Masood A. Khan, Richard M. Gallo, Gourapura J. Renukaradhya, Wenjun Du, Jacquelyn Gervay-Hague, and Randy R. Brutkiewicz
J Immunol 2009 182: 4744-4750; doi:10.4049/jimmunol.0804311 [Abstract] [Full Text] [PDF] Data Supplement  

Association of HIV-Specific and Total CD8⁺ T Memory Phenotypes in Subtype C HIV-1 Infection with Viral Set Point

Wendy A. Burgers, Catherine Riou, Mandla Mlotshwa, Pholo Maenetje, Debra de Assis Rosa, Jason Brenchley, Koleka Mlisana, Daniel C. Douek, Richard Koup, Mario Roederer, Guy de Bruyn, Salim Abdool Karim, Carolyn Williamson, Clive M. Gray and the CAPRISA 002 Acute Infection Study Team
J Immunol 2009 182: 4751-4761; doi:10.4049/jimmunol.0803801 [Abstract] [Full Text] [PDF] Data Supplement  

Drak2 Is Upstream of p70S6 Kinase: Its Implication in Cytokine-Induced Islet Apoptosis, Diabetes, and Islet Transplantation

Jianning Mao, Hongyu Luo, Bing Han, Richard Bertrand, and Jiangping Wu
J Immunol 2009 182: 4762-4770; doi:10.4049/jimmunol.0802255 [Abstract] [Full Text] [PDF]  

CD30 Is Required for CCL21 Expression and CD4 T Cell Recruitment in the Absence of Lymphotoxin Signals

Vasileios Bekiaris, Fabrina Gaspal, Mi-Yeon Kim, David R. Withers, Fiona M. McConnell, Graham Anderson, and Peter J. L. Lane
J Immunol 2009 182: 4771-4775; doi:10.4049/jimmunol.0803481 [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Interaction of Bap31 and MHC Class I Molecules and Their Traffic Out of the Endoplasmic Reticulum

Fumiyoshi Abe, Nancy Van Prooyen, John J. Ladasky, and Michael Edidin
J Immunol 2009 182: 4776-4783; doi:10.4049/jimmunol.0800242 [Abstract] [Full Text] [PDF] Data Supplement  

Natural Lipid Ligands Associated with Human CD1d Targeted to Different Subcellular Compartments

Weiming Yuan, Suk-Jo Kang, James E. Evans, and Peter Cresswell
J Immunol 2009 182: 4784-4791; doi:10.4049/jimmunol.0803981 [Abstract] [Full Text] [PDF] Data Supplement  

Evolution of the Ikaros Gene Family: Implications for the Origins of Adaptive Immunity

Liza B. John, Simon Yoong, and Alister C. Ward
J Immunol 2009 182: 4792-4799; doi:10.4049/jimmunol.0802372 [Abstract] [Full Text] [PDF] Data Supplement  

Brief Residence at the Plasma Membrane of the MHC Class I-Related Chain B Is Due to Clathrin-Mediated Cholesterol-Dependent Endocytosis and Shedding

Sonia Agüera-González, Philippe Boutet, Hugh T. Reyburn, and Mar Valés-Gómez
J Immunol 2009 182: 4800-4808; doi:10.4049/jimmunol.0800713 [Abstract] [Full Text] [PDF] Data Supplement  

Steric Hindrance and Fast Dissociation Explain the Lack of Immunogenicity of the Minor Histocompatibility HA-1^Arg Null Allele

Eric Spierings, Stéphanie Gras, Jean-Baptiste Reiser, Bregje Mommaas, Mathilde Almekinders, Michel G. D. Kester, Anne Chouquet, Madalen Le Gorrec, Jan W. Drijfhout, Ferry Ossendorp, Dominique Housset, and Els Goulmy
J Immunol 2009 182: 4809-4816; doi:10.4049/jimmunol.0803911 [Abstract] [Full Text] [PDF] Data Supplement  

Trimolecular Complex Formation of IgE, FcRI, and a Recombinant Nonanaphylactic Single-Chain Antibody Fragment with High Affinity for IgE

Christian Lupinek, Kenneth H. Roux, Sylvia Laffer, Ingrid Rauter, Kavita Reginald, Michael Kneidinger, Katharina Blatt, Tanja Ball, Ines Pree, Beatrice Jahn-Schmid, Jean-Pierre Allam, Natalija Novak, Anja Drescher, Franz Kricek, Peter Valent, Hakan Englund, and Rudolf Valenta
J Immunol 2009 182: 4817-4829; doi:10.4049/jimmunol.0800726 [Abstract] [Full Text] [PDF]  

N-Glycosylation Enhances Presentation of a MHC Class I-Restricted Epitope from Tyrosinase

Marina Ostankovitch, Michelle Altrich-VanLith, Valentina Robila, and Victor H. Engelhard
J Immunol 2009 182: 4830-4835; doi:10.4049/jimmunol.0802902 [Abstract] [Full Text] [PDF]  

Thrombin Binding Predicts the Effects of Sequence Changes in a Human Monoclonal Antiphospholipid Antibody on Its In Vivo Biologic Actions

Ian Giles, Charis Pericleous, Xiaowei Liu, Jasmine Ehsanullah, Lindsey Clarke, Paul Brogan, Marvin Newton-West, Robert Swerlick, Anastasia Lambrianides, Pojen Chen, David Latchman, David Isenberg, Silvia Pierangeli, and Anisur Rahman
J Immunol 2009 182: 4836-4843; doi:10.4049/jimmunol.0804241 [Abstract] [Full Text] [PDF]  

Critical and Multiple Roles for the CD3 Intracytoplasmic Tail in Double Negative to Double Positive Thymocyte Differentiation

Jean-Francois Brodeur, Samantha Li, Maria da Silva Martins, Louise Larose, and Vibhuti P. Dave
J Immunol 2009 182: 4844-4853; doi:10.4049/jimmunol.0803679 [Abstract] [Full Text] [PDF] Data Supplement  

HOST DEFENSE:

Selective Transcriptional Down-Regulation of Human Rhinovirus-Induced Production of CXCL10 from Airway Epithelial Cells via the MEK1 Pathway

Raza S. Zaheer, Rommy Koetzler, Neil S. Holden, Shahina Wiehler, and David Proud
J Immunol 2009 182: 4854-4864; doi:10.4049/jimmunol.0802401 [Abstract] [Full Text] [PDF]  

A Protective Role for Dengue Virus-Specific CD8⁺ T Cells

Lauren E. Yauch, Raphaël M. Zellweger, Maya F. Kotturi, Afrina Qutubuddin, John Sidney, Bjoern Peters, Tyler R. Prestwood, Alessandro Sette, and Sujan Shresta
J Immunol 2009 182: 4865-4873; doi:10.4049/jimmunol.0801974 [Abstract] [Full Text] [PDF]  

Host-Derived Interleukin-1 Is Important in Determining the Immunogenicity of 3-Methylcholantrene Tumor Cells

Moshe Elkabets, Yakov Krelin, Shahar Dotan, Adelheid Cerwenka, Angel Porgador, Rachel G. Lichtenstein, Malka R. White, Margot Zoller, Yoichizo Iwakura, Charles A. Dinarello, Elena Voronov, and Ron N. Apte
J Immunol 2009 182: 4874-4881; doi:10.4049/jimmunol.0803916 [Abstract] [Full Text] [PDF]  

Protective Response to Leishmania major in BALB/c Mice Requires Antigen Processing in the Absence of DM

Tirumalai Kamala and Navreet K. Nanda
J Immunol 2009 182: 4882-4890; doi:10.4049/jimmunol.0803956 [Abstract] [Full Text] [PDF] Data Supplement  

Group V Secretory Phospholipase A₂ Modulates Phagosome Maturation and Regulates the Innate Immune Response against Candida albicans

Barbara Balestrieri, Akiko Maekawa, Wei Xing, Michael H. Gelb, Howard R. Katz, and Jonathan P. Arm
J Immunol 2009 182: 4891-4898; doi:10.4049/jimmunol.0803776 [Abstract] [Full Text] [PDF]  

Differential Requirements for Protection against Mucosal Challenge with Francisella tularensis in the Presence versus Absence of Cholera Toxin B and Inactivated F. tularensis

Constantine Bitsaktsis, Deepak B. Rawool, Ying Li, Nitin V. Kurkure, Bibiana Iglesias, and Edmund J. Gosselin
J Immunol 2009 182: 4899-4909; doi:10.4049/jimmunol.0803242 [Abstract] [Full Text] [PDF]  

The NF-B RelA Subunit Confers Resistance to Leishmania major by Inducing Nitric Oxide Synthase 2 and Fas Expression but Not Th1 Differentiation

Setsuko Mise-Omata, Etsushi Kuroda, Tsutomu Sugiura, Uki Yamashita, Yuichi Obata, and Takahiro S. Doi
J Immunol 2009 182: 4910-4916; doi:10.4049/jimmunol.0800967 [Abstract] [Full Text] [PDF]  

A Novel Hybrid Yeast-Human Network Analysis Reveals an Essential Role for FNBP1L in Antibacterial Autophagy

Alan Huett, Aylwin Ng, Zhifang Cao, Petric Kuballa, Masaaki Komatsu, Mark J. Daly, Daniel K. Podolsky, and Ramnik J. Xavier
J Immunol 2009 182: 4917-4930; doi:10.4049/jimmunol.0803050 [Abstract] [Full Text] [PDF] Data Supplement  

Important Role for CC Chemokine Ligand 2-Dependent Lung Mononuclear Phagocyte Recruitment to Inhibit Sepsis in Mice Infected with Streptococcus pneumoniae

Christine Winter, Wiebke Herbold, Regina Maus, Florian Länger, David E. Briles, James C. Paton, Tobias Welte, and Ulrich A. Maus
J Immunol 2009 182: 4931-4937; doi:10.4049/jimmunol.0804096 [Abstract] [Full Text] [PDF]  

Requisite Role for the Dectin-1 β-Glucan Receptor in Pulmonary Defense against Aspergillus fumigatus

Jessica L. Werner, Allison E. Metz, Dawn Horn, Trenton R. Schoeb, Matthew M. Hewitt, Lisa M. Schwiebert, Ines Faro-Trindade, Gordon D. Brown, and Chad Steele
J Immunol 2009 182: 4938-4946; doi:10.4049/jimmunol.0804250 [Abstract] [Full Text] [PDF]  

Lipocalin 2 Is Required for Pulmonary Host Defense against Klebsiella Infection

Yvonne R. Chan, Jessica S. Liu, Derek A. Pociask, Mingquan Zheng, Timothy A. Mietzner, Thorsten Berger, Tak W. Mak, Matthew C. Clifton, Roland K. Strong, Prabir Ray, and Jay K. Kolls
J Immunol 2009 182: 4947-4956; doi:10.4049/jimmunol.0803282 [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Contribution of Adenosine A2B Receptors to Inflammatory Parameters of Experimental Colitis

Julia-Stefanie Frick, Christopher F. MacManus, Melanie Scully, Louise E. Glover, Holger K. Eltzschig, and Sean P. Colgan
J Immunol 2009 182: 4957-4964; doi:10.4049/jimmunol.0801324 [Abstract] [Full Text] [PDF]  

Heat Shock Protein 96 Is Elevated in Rheumatoid Arthritis and Activates Macrophages Primarily via TLR2 Signaling

Qi-Quan Huang, Rudina Sobkoviak, Angela R. Jockheck-Clark, Bo Shi, Arthur M. Mandelin, II, Paul Peter Tak, G. Kennith Haines, III, Christopher V. Nicchitta, and Richard M. Pope
J Immunol 2009 182: 4965-4973; doi:10.4049/jimmunol.0801563 [Abstract] [Full Text] [PDF]  

Formyl Peptide Receptor-Like 2 Is Expressed and Functional in Plasmacytoid Dendritic Cells, Tissue-Specific Macrophage Subpopulations, and Eosinophils

Thalie Devosse, Aude Guillabert, Nicky D'Haene, Alix Berton, Patricia De Nadai, Sophie Noel, Maryse Brait, Jean-Denis Franssen, Silvano Sozzani, Isabelle Salmon, and Marc Parmentier
J Immunol 2009 182: 4974-4984; doi:10.4049/jimmunol.0803128 [Abstract] [Full Text] [PDF]  

Role of the Heparan Sulfate Proteoglycan Syndecan-1 (CD138) in Delayed-Type Hypersensitivity

Behzad Kharabi Masouleh, Gerdy B. Ten Dam, Martin K. Wild, Ruth Seelige, Johan van der Vlag, Angelique L. Rops, Frank G. Echtermeyer, Dietmar Vestweber, Toin H. van Kuppevelt, Ludwig Kiesel, and Martin Götte
J Immunol 2009 182: 4985-4993; doi:10.4049/jimmunol.0800574 [Abstract] [Full Text] [PDF] Data Supplement  

MicroRNA-21 Is Up-Regulated in Allergic Airway Inflammation and Regulates IL-12p35 Expression

Thomas X. Lu, Ariel Munitz, and Marc E. Rothenberg
J Immunol 2009 182: 4994-5002; doi:10.4049/jimmunol.0803560 [Abstract] [Full Text] [PDF] Data Supplement  

IL-20 Is Regulated by Hypoxia-Inducible Factor and Up-Regulated after Experimental Ischemic Stroke

Wei-Yu Chen and Ming-Shi Chang
J Immunol 2009 182: 5003-5012; doi:10.4049/jimmunol.0803653 [Abstract] [Full Text] [PDF] Data Supplement  

Functional Blocking Monoclonal Antibodies against IL-12p40 Homodimer Inhibit Adoptive Transfer of Experimental Allergic Encephalomyelitis

Susanta Mondal, Avik Roy, and Kalipada Pahan
J Immunol 2009 182: 5013-5023; doi:10.4049/jimmunol.0801734 [Abstract] [Full Text] [PDF]  

The Pattern Recognition Receptor CD36 Is a Chondrocyte Hypertrophy Marker Associated with Suppression of Catabolic Responses and Promotion of Repair Responses to Inflammatory Stimuli

Denise L. Cecil, C. Thomas G. Appleton, Monika D. Polewski, John S. Mort, Ann Marie Schmidt, Alison Bendele, Frank Beier, and Robert Terkeltaub
J Immunol 2009 182: 5024-5031; doi:10.4049/jimmunol.0803603 [Abstract] [Full Text] [PDF]  

The Atypical Chemokine Receptor D6 Contributes to the Development of Experimental Colitis

Yvonne Bordon, Chris A. H. Hansell, David P. Sester, Mairi Clarke, Allan McI. Mowat, and Robert J. B. Nibbs
J Immunol 2009 182: 5032-5040; doi:10.4049/jimmunol.0802802 [Abstract] [Full Text] [PDF] Data Supplement  

A Novel and Critical Role for Tyrosine 663 in Platelet Endothelial Cell Adhesion Molecule-1 Trafficking and Transendothelial Migration

Bidisha Dasgupta, Eric Dufour, Zahra Mamdouh, and William A. Muller
J Immunol 2009 182: 5041-5051; doi:10.4049/jimmunol.0803192 [Abstract] [Full Text] [PDF]  

P2X7 Receptor-Stimulated Secretion of MHC Class II-Containing Exosomes Requires the ASC/NLRP3 Inflammasome but Is Independent of Caspase-1

Yan Qu, Lakshmi Ramachandra, Susanne Mohr, Luigi Franchi, Clifford V. Harding, Gabriel Nunez, and George R. Dubyak
J Immunol 2009 182: 5052-5062; doi:10.4049/jimmunol.0802968 [Abstract] [Full Text] [PDF] Data Supplement  

p53 Attenuates Lipopolysaccharide-Induced NF-B Activation and Acute Lung Injury

Gang Liu, Young-Jun Park, Yuko Tsuruta, Emmanuel Lorne, and Edward Abraham
J Immunol 2009 182: 5063-5071; doi:10.4049/jimmunol.0803526 [Abstract] [Full Text] [PDF] Data Supplement  

Mitocryptide-2: Purification, Identification, and Characterization of a Novel Cryptide That Activates Neutrophils

Hidehito Mukai, Tetsuo Seki, Hiroko Nakano, Yoshinori Hokari, Toshifumi Takao, Masanori Kawanami, Hiroyuki Tsukagoshi, Hirokazu Kimura, Yoshiaki Kiso, Yasutsugu Shimonishi, Yoshisuke Nishi, and Eisuke Munekata
J Immunol 2009 182: 5072-5080; doi:10.4049/jimmunol.0802965 [Abstract] [Full Text] [PDF]  

Adaptor Proteins and Ras Synergistically Regulate IL-1-Induced ADAMTS-4 Expression in Human Chondrocytes

Rasheed Ahmad, Judith Sylvester, Mushtaq Ahmad, and Muhammad Zafarullah
J Immunol 2009 182: 5081-5087; doi:10.4049/jimmunol.0803544 [Abstract] [Full Text] [PDF]  

Bruton’s Tyrosine Kinase Is Involved in miR-346-Related Regulation of IL-18 Release by Lipopolysaccharide-Activated Rheumatoid Fibroblast-Like Synoviocytes

Ghada Alsaleh, Guillaume Suffert, Noha Semaan, Tom Juncker, Laurent Frenzel, Jacques-Eric Gottenberg, Jean Sibilia, Sébastien Pfeffer, and Dominique Wachsmann
J Immunol 2009 182: 5088-5097; doi:10.4049/jimmunol.0801613 [Abstract] [Full Text] [PDF]  

Acidic Mammalian Chitinase Regulates Epithelial Cell Apoptosis via a Chitinolytic-Independent Mechanism

Dominik Hartl, Chuan Hua He, Babara Koller, Carla A. Da Silva, Yasushi Kobayashi, Chun Geun Lee, Richard A. Flavell, and Jack A. Elias
J Immunol 2009 182: 5098-5106; doi:10.4049/jimmunol.0803446 [Abstract] [Full Text] [PDF]  

Pathogenesis of Steroid-Resistant Airway Hyperresponsiveness: Interaction between IFN- and TLR4/MyD88 Pathways

Ming Yang, Rakesh K. Kumar, and Paul S. Foster
J Immunol 2009 182: 5107-5115; doi:10.4049/jimmunol.0803468 [Abstract] [Full Text] [PDF]  

Induction of Airway Hyperreactivity by IL-25 Is Dependent on a Subset of Invariant NKT Cells Expressing IL-17RB

Philippe Stock, Vincent Lombardi, Viola Kohlrautz, and Omid Akbari
J Immunol 2009 182: 5116-5122; doi:10.4049/jimmunol.0804213 [Abstract] [Full Text] [PDF]  

A Protective Role for C5a in the Development of Allergic Asthma Associated with Altered Levels of B7-H1 and B7-DC on Plasmacytoid Dendritic Cells

Xun Zhang, Ian P. Lewkowich, Gabriele Köhl, Jennifer R. Clark, Marsha Wills-Karp, and Jörg Köhl
J Immunol 2009 182: 5123-5130; doi:10.4049/jimmunol.0804276 [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

HLA-DQ8 (DQB1*0302)-Restricted Th17 Cells Exacerbate Experimental Autoimmune Encephalomyelitis in HLA-DR3-Transgenic Mice

Ashutosh Mangalam, David Luckey, Eati Basal, Megan Jackson, Michele Smart, Moses Rodriguez, and Chella David
J Immunol 2009 182: 5131-5139; doi:10.4049/jimmunol.0803918 [Abstract] [Full Text] [PDF]  

Enrichment of Human CD4⁺ V24/Vβ11 Invariant NKT Cells in Intrahepatic Malignant Tumors

Gabriel Bricard, Valerie Cesson, Estelle Devevre, Hanifa Bouzourene, Catherine Barbey, Nathalie Rufer, Jin S. Im, Pedro M. Alves, Olivier Martinet, Nermin Halkic, Jean-Charles Cerottini, Pedro Romero, Steven A. Porcelli, H. Robson MacDonald, and Daniel E. Speiser
J Immunol 2009 182: 5140-5151; doi:10.4049/jimmunol.0711086 [Abstract] [Full Text] [PDF]  

CORRECTIONS:

ISCOMATRIX adjuvant induces efficient cross-presentation of tumor Ag by dendritic cells via rapid cytosolic Ag delivery and processing via tripeptidyl peptidase II

M. Schnurr, M. Orban, N. C. Robson, A. Shin, H. Braley, D. Airey, J. Cebon, E. Maraskovsky, and S. Endres
J Immunol 2009 182: 5152; doi:10.4049/jimmunol.0990022 [Full Text] [PDF]  

Linking C5 deficiency to an exonic splicing enhancer mutation

N. Pfarr, D. Prawitt, M. Kirschfink, C. Schroff, M. Knuf, P. Habermehl, W. Mannhardt, F. Zepp, W. Fairbrother, M. Loos, C. B. Burge, and J. Pohlenz
J Immunol 2009 182: 5152; doi:10.4049/jimmunol.0990023 [Full Text] [PDF]  

Extracellular granzymes A and B in humans: Detection of native species during CTL responses in vitro and in vivo

E. H. A. Spaeny-Dekking, W. L. Hanna, A. M. Wolbink, P. C. Wever, A. J. Kummer, A. J. G. Swaak, J. M. Middeldorp, H. G. Huisman, C. J. Froelich, and C. E. Hack
J Immunol 2009 182: 5152; doi:10.4049/jimmunol.0990024 [Full Text] [PDF]  

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