IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2009 182: 2555-2556; doi:10.4049/jimmunol.0990008 [Full Text] [PDF] ImmunoCast  

PILLARS OF IMMUNOLOGY:

Turning the Tide of Lymphocyte Costimulation

Yuwen Zhu and Lieping Chen
J Immunol 2009 182: 2557-2558; doi:10.4049/jimmunol.0990006 [Full Text] [PDF] [Original Pillars Article]  

Pillars Article: T-Cell Antigen CD28 Mediates Adhesion with B Cells by Interacting with Activation Antigen B7/BB-1. 1990. Proc. Natl. Acad. Sci. USA 87: 5031–5035

Peter S. Linsley, Edward A. Clark, and Jeffrey A. Ledbetter
J Immunol 2009 182: 2559-2563 [PDF]  

CUTTING EDGE:

Cutting Edge: In Vitro Generated Th17 Cells Maintain Their Cytokine Expression Program in Normal but Not Lymphopenic Hosts

Roza Nurieva, Xuexian O. Yang, Yeonseok Chung, and Chen Dong
J Immunol 2009 182: 2565-2568; doi:10.4049/jimmunol.0803931 [Abstract] [Full Text] [PDF]  

Cutting Edge: Killer Ig-Like Receptors Mediate "Missing Self" Recognition In Vivo

Jeroen van Bergen, Allan Thompson, Christelle Retière, John Trowsdale, and Frits Koning
J Immunol 2009 182: 2569-2572; doi:10.4049/jimmunol.0804042 [Abstract] [Full Text] [PDF]  

Cutting Edge: Mucosal Application of a Lyophilized Viral Vector Vaccine Confers Systemic and Protective Immunity toward Intracellular Pathogens

Wolfgang Kastenmuller, Georg Gasteiger, Leon Stross, Dirk H. Busch, and Ingo Drexler
J Immunol 2009 182: 2573-2577; doi:10.4049/jimmunol.0803871 [Abstract] [Full Text] [PDF] Data Supplement  

Cutting Edge: The Foxp3 Target miR-155 Contributes to the Development of Regulatory T Cells

Susan Kohlhaas, Oliver A. Garden, Cheryl Scudamore, Martin Turner, Klaus Okkenhaug, and Elena Vigorito
J Immunol 2009 182: 2578-2582; doi:10.4049/jimmunol.0803162 [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

FcRn in the Yolk Sac Endoderm of Mouse Is Required for IgG Transport to Fetus

Jonghan Kim, Sudhasri Mohanty, Latha P. Ganesan, Keding Hua, David Jarjoura, William L. Hayton, John M. Robinson, and Clark L. Anderson
J Immunol 2009 182: 2583-2589; doi:10.4049/jimmunol.0803247 [Abstract] [Full Text] [PDF]  

Amplification of Autoimmune Response through Induction of Dendritic Cell Maturation in Inflamed Tissues

Kristin Melli, Rachel S. Friedman, Ashley E. Martin, Erik B. Finger, Gang Miao, Gregory L. Szot, Matthew F. Krummel, and Qizhi Tang
J Immunol 2009 182: 2590-2600; doi:10.4049/jimmunol.0803543 [Abstract] [Full Text] [PDF] Data Supplement  

The Essential Role of Single Ig IL-1 Receptor-Related Molecule/Toll IL-1R8 in Regulation of Th2 Immune Response

Katarzyna Bulek, Shadi Swaidani, Jinzhong Qin, Yi Lu, Muhammet F. Gulen, Tomasz Herjan, Booki Min, Robert A. Kastelein, Mark Aronica, Magdalena Kosz-Vnenchak, and Xiaoxia Li
J Immunol 2009 182: 2601-2609; doi:10.4049/jimmunol.0802729 [Abstract] [Full Text] [PDF]  

Chemokine Receptor CXCR5 Supports Solitary Intestinal Lymphoid Tissue Formation, B Cell Homing, and Induction of Intestinal IgA Responses

Sarvari Velaga, Heike Herbrand, Michaela Friedrichsen, Tian Jiong, Martina Dorsch, Matthias W. Hoffmann, Reinhold Förster, and Oliver Pabst
J Immunol 2009 182: 2610-2619; doi:10.4049/jimmunol.0801141 [Abstract] [Full Text] [PDF]  

Selective Inhibition of CCR2 Expressing Lymphomyeloid Cells in Experimental Autoimmune Encephalomyelitis by a GM-CSF-MCP1 Fusokine

Moutih Rafei, Philippe M. Campeau, Jian Hui Wu, Elena Birman, Kathy Forner, Marie-Noelle Boivin, and Jacques Galipeau
J Immunol 2009 182: 2620-2627; doi:10.4049/jimmunol.0803495 [Abstract] [Full Text] [PDF] Data Supplement  

Transgenic Inhibition of Astroglial NF-B Improves Functional Outcome in Experimental Autoimmune Encephalomyelitis by Suppressing Chronic Central Nervous System Inflammation

Roberta Brambilla, Trikaldarshi Persaud, Xianchen Hu, Shaffiat Karmally, Valery I. Shestopalov, Galina Dvoriantchikova, Dmitry Ivanov, Lubov Nathanson, Scott R. Barnum, and John R. Bethea
J Immunol 2009 182: 2628-2640; doi:10.4049/jimmunol.0802954 [Abstract] [Full Text] [PDF] Data Supplement  

Suppression of Autoimmune Diabetes by Soluble Galectin-1

Marcelo J. Perone, Suzanne Bertera, William J. Shufesky, Sherrie J. Divito, Angela Montecalvo, Alicia R. Mathers, Adriana T. Larregina, Mabel Pang, Nilufer Seth, Kai W. Wucherpfennig, Massimo Trucco, Linda G. Baum, and Adrian E. Morelli
J Immunol 2009 182: 2641-2653; doi:10.4049/jimmunol.0800839 [Abstract] [Full Text] [PDF]  

Gap Junction Communication between Autologous Endothelial and Tumor Cells Induce Cross-Recognition and Elimination by Specific CTL

Houssem Benlalam, Abdelali Jalil, Meriem Hasmim, Baoxu Pang, Ryad Tamouza, Michèle Mitterrand, Yann Godet, Nathalie Lamerant, Caroline Robert, Marie-Françoise Avril, Jacques Neefjes, Thomas Tursz, Fathia Mami-Chouaib, Claudine Kieda, and Salem Chouaib
J Immunol 2009 182: 2654-2664; doi:10.4049/jimmunol.0800815 [Abstract] [Full Text] [PDF] Data Supplement  

IL-17 Signaling-Independent Central Nervous System Autoimmunity Is Negatively Regulated by TGF-β

Ines Gonzalez-García, Yani Zhao, Songguang Ju, Qin Gu, Lin Liu, Jay K. Kolls, and Binfeng Lu
J Immunol 2009 182: 2665-2671; doi:10.4049/jimmunol.0802221 [Abstract] [Full Text] [PDF] Data Supplement  

Bone Marrow Monocyte PECAM-1 Deficiency Elicits Increased Osteoclastogenesis Resulting in Trabecular Bone Loss

Yue Wu, Kathryn Tworkoski, Michael Michaud, and Joseph A. Madri
J Immunol 2009 182: 2672-2679; doi:10.4049/jimmunol.0802398 [Abstract] [Full Text] [PDF]  

STAT6 Deletion Converts the Th2 Inflammatory Pathology Afflicting Lat^Y136F Mice into a Lymphoproliferative Disorder Involving Th1 and CD8 Effector T Cells

Cristel Archambaud, Amandine Sansoni, Michael Mingueneau, Elisabeth Devilard, Georges Delsol, Bernard Malissen, and Marie Malissen
J Immunol 2009 182: 2680-2689; doi:10.4049/jimmunol.0803257 [Abstract] [Full Text] [PDF]  

Reduced Thymic Aire Expression and Abnormal NF-B2 Signaling in a Model of Systemic Autoimmunity

Anne L. Fletcher, Natalie Seach, Jessica J. Reiseger, Tamara E. Lowen, Maree V. Hammett, Hamish S. Scott, and Richard L. Boyd
J Immunol 2009 182: 2690-2699; doi:10.4049/jimmunol.0801752 [Abstract] [Full Text] [PDF]  

Temporal Changes in Myeloid Cells in the Cervix during Pregnancy and Parturition

Brenda C. Timmons, Anna-Marie Fairhurst, and Mala S. Mahendroo
J Immunol 2009 182: 2700-2707; doi:10.4049/jimmunol.0803138 [Abstract] [Full Text] [PDF]  

The Glucocorticoid-Induced TNF Receptor-Related Protein (GITR)-GITR Ligand Pathway Acts As a Mediator of Cutaneous Dendritic Cell Migration and Promotes T Cell-Mediated Acquired Immunity

Yosuke Kamimura, Hideyuki Iwai, Jinhua Piao, Masaaki Hashiguchi, and Miyuki Azuma
J Immunol 2009 182: 2708-2716; doi:10.4049/jimmunol.0803704 [Abstract] [Full Text] [PDF]  

The Levels of Retinoic Acid-Inducible Gene I Are Regulated by Heat Shock Protein 90-

Tomoh Matsumiya, Tadaatsu Imaizumi, Hidemi Yoshida, Kei Satoh, Matthew K. Topham, and Diana M. Stafforini
J Immunol 2009 182: 2717-2725; doi:10.4049/jimmunol.0802933 [Abstract] [Full Text] [PDF]  

Antigen Processing and MHC-II Presentation by Dermal and Tumor-Infiltrating Dendritic Cells

Michael Y. Gerner and Matthew F. Mescher
J Immunol 2009 182: 2726-2737; doi:10.4049/jimmunol.0803479 [Abstract] [Full Text] [PDF]  

Bone Marrow Chimeras and c-fms Conditional Ablation (Mafia) Mice Reveal an Essential Role for Resident Myeloid Cells in Lipopolysaccharide/TLR4-Induced Corneal Inflammation

Holly R. Chinnery, Eric C. Carlson, Yan Sun, Michelle Lin, Sandra H. Burnett, Victor L. Perez, Paul G. McMenamin, and Eric Pearlman
J Immunol 2009 182: 2738-2744; doi:10.4049/jimmunol.0803505 [Abstract] [Full Text] [PDF]  

Chemotaxis and Phagocytosis in Neutrophils Is Independent of Coronin 1

Benoit Combaluzier and Jean Pieters
J Immunol 2009 182: 2745-2752; doi:10.4049/jimmunol.0801812 [Abstract] [Full Text] [PDF]  

NK-Dependent Increases in CCL22 Secretion Selectively Recruits Regulatory T Cells to the Tumor Microenvironment

Adam W. Mailloux and M. Rita I. Young
J Immunol 2009 182: 2753-2765; doi:10.4049/jimmunol.0801124 [Abstract] [Full Text] [PDF]  

Influenza Virus and Poly(I:C) Inhibit MHC Class I-Restricted Presentation of Cell-Associated Antigens Derived from Infected Dead Cells Captured by Human Dendritic Cells

Davor Frleta, Chun I. Yu, Eynav Klechevsky, Anne-Laure Flamar, Gerard Zurawski, Jacques Banchereau, and A. Karolina Palucka
J Immunol 2009 182: 2766-2776; doi:10.4049/jimmunol.0801720 [Abstract] [Full Text] [PDF] Data Supplement  

Ly6C^low Monocytes Differentiate into Dendritic Cells and Cross-Tolerize T Cells through PDL-1

YuFeng Peng, Yvette Latchman, and Keith B. Elkon
J Immunol 2009 182: 2777-2785; doi:10.4049/jimmunol.0803172 [Abstract] [Full Text] [PDF]  

Programming for CD8 T Cell Memory Development Requires IL-12 or Type I IFN

Zhengguo Xiao, Kerry A. Casey, Stephen C. Jameson, Julie M. Curtsinger, and Matthew F. Mescher
J Immunol 2009 182: 2786-2794; doi:10.4049/jimmunol.0803484 [Abstract] [Full Text] [PDF]  

Human Dendritic Cells Produce TGF-β1 under the Influence of Lung Carcinoma Cells and Prime the Differentiation of CD4⁺CD25⁺Foxp3⁺ Regulatory T Cells

Ingrid E. Dumitriu, Donald R. Dunbar, Sarah E. Howie, Tariq Sethi, and Christopher D. Gregory
J Immunol 2009 182: 2795-2807; doi:10.4049/jimmunol.0712671 [Abstract] [Full Text] [PDF]  

A Pivotal Role for CD40-Mediated IL-6 Production by Dendritic Cells during IL-17 Induction In Vivo

Georgia Perona-Wright, Stephen J. Jenkins, Richard A. O'Connor, Dimitrios Zienkiewicz, Henry J. McSorley, Rick M. Maizels, Stephen M. Anderton, and Andrew S. MacDonald
J Immunol 2009 182: 2808-2815; doi:10.4049/jimmunol.0803553 [Abstract] [Full Text] [PDF]  

PD-1/PD-L Blockade Prevents Anergy Induction and Enhances the Anti-Tumor Activities of Glycolipid-Activated Invariant NKT Cells

Vrajesh V. Parekh, Saif Lalani, Sungjune Kim, Ramesh Halder, Miyuki Azuma, Hideo Yagita, Vipin Kumar, Lan Wu, and Luc Van Kaer
J Immunol 2009 182: 2816-2826; doi:10.4049/jimmunol.0803648 [Abstract] [Full Text] [PDF] Data Supplement  

Engagement of CD83 on B Cells Modulates B Cell Function In Vivo

Birte Kretschmer, Katja Lüthje, Stefanie Schneider, Bernhard Fleischer, and Minka Breloer
J Immunol 2009 182: 2827-2834; doi:10.4049/jimmunol.0803153 [Abstract] [Full Text] [PDF] Data Supplement  

IL-3 Induces Basophil Expansion In Vivo by Directing Granulocyte-Monocyte Progenitors to Differentiate into Basophil Lineage-Restricted Progenitors in the Bone Marrow and by Increasing the Number of Basophil/Mast Cell Progenitors in the Spleen

Keitaro Ohmori, Yuchun Luo, Yi Jia, Jun Nishida, Zhengqi Wang, Kevin D. Bunting, Demin Wang, and Hua Huang
J Immunol 2009 182: 2835-2841; doi:10.4049/jimmunol.0802870 [Abstract] [Full Text] [PDF]  

Ultraviolet B Radiation Generated Platelet-Activating Factor Receptor Agonist Formation Involves EGF-R-Mediated Reactive Oxygen Species

Yongxue Yao, Jay E. Wolverton, Qiwei Zhang, Gopal K. Marathe, Mohammed Al-Hassani, Raymond L. Konger, and Jeffrey B. Travers
J Immunol 2009 182: 2842-2848; doi:10.4049/jimmunol.0802689 [Abstract] [Full Text] [PDF]  

Hantaan Virus Triggers TLR3-Dependent Innate Immune Responses

Wiebke Handke, Robin Oelschlegel, Renate Franke, Detlev H. Krüger, and Andreas Rang
J Immunol 2009 182: 2849-2858; doi:10.4049/jimmunol.0802893 [Abstract] [Full Text] [PDF]  

IL-21 Mediates Suppressive Effects via Its Induction of IL-10

Rosanne Spolski, Hyoung-Pyo Kim, Wei Zhu, David E. Levy, and Warren J. Leonard
J Immunol 2009 182: 2859-2867; doi:10.4049/jimmunol.0802978 [Abstract] [Full Text] [PDF] Data Supplement  

Transitional B Cells Exhibit a B Cell Receptor-Specific Nuclear Defect in Gene Transcription

Sarah F. Andrews and David J. Rawlings
J Immunol 2009 182: 2868-2878; doi:10.4049/jimmunol.0802368 [Abstract] [Full Text] [PDF]  

NK Cell Enhancement of Antigen Presentation by B Lymphocytes

Paula Jennings and Dorothy Yuan
J Immunol 2009 182: 2879-2887; doi:10.4049/jimmunol.0803220 [Abstract] [Full Text] [PDF]  

HIV-1 Tat Addresses Dendritic Cells to Induce a Predominant Th1-Type Adaptive Immune Response That Appears Prevalent in the Asymptomatic Stage of Infection

Emanuele Fanales-Belasio, Sonia Moretti, Valeria Fiorelli, Antonella Tripiciano, Maria R. Pavone Cossut, Arianna Scoglio, Barbara Collacchi, Filomena Nappi, Iole Macchia, Stefania Bellino, Vittorio Francavilla, Antonella Caputo, Giovanni Barillari, Mauro Magnani, Maria Elena Laguardia, Aurelio Cafaro, Fausto Titti, Paolo Monini, Fabrizio Ensoli, and Barbara Ensoli
J Immunol 2009 182: 2888-2897; doi:10.4049/jimmunol.0711406 [Abstract] [Full Text] [PDF]  

NAD⁺ and ATP Released from Injured Cells Induce P2X₇-Dependent Shedding of CD62L and Externalization of Phosphatidylserine by Murine T Cells

Felix Scheuplein, Nicole Schwarz, Sahil Adriouch, Christian Krebs, Peter Bannas, Björn Rissiek, Michel Seman, Friedrich Haag, and Friedrich Koch-Nolte
J Immunol 2009 182: 2898-2908; doi:10.4049/jimmunol.0801711 [Abstract] [Full Text] [PDF]  

Preferential Use of B7.2 and Not B7.1 in Priming of Vaccinia Virus-Specific CD8 T Cells

Shahram Salek-Ardakani, Ramon Arens, Rachel Flynn, Alessandro Sette, Stephen P. Schoenberger, and Michael Croft
J Immunol 2009 182: 2909-2918; doi:10.4049/jimmunol.0803545 [Abstract] [Full Text] [PDF]  

Reversal of Human Papillomavirus-Specific T Cell Immune Suppression through TLR Agonist Treatment of Langerhans Cells Exposed to Human Papillomavirus Type 16

Laura M. Fahey, Adam B. Raff, Diane M. Da Silva, and W. Martin Kast
J Immunol 2009 182: 2919-2928; doi:10.4049/jimmunol.0803645 [Abstract] [Full Text] [PDF]  

Analysis of Adhesion Molecules, Target Cells, and Role of IL-2 in Human FOXP3⁺ Regulatory T Cell Suppressor Function

Dat Q. Tran, Deborah D. Glass, Gulbu Uzel, Dirk A. Darnell, Christine Spalding, Steven M. Holland, and Ethan M. Shevach
J Immunol 2009 182: 2929-2938; doi:10.4049/jimmunol.0803827 [Abstract] [Full Text] [PDF] Data Supplement  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Polymorphisms in Mannan-Binding Lectin (MBL)-Associated Serine Protease 2 Affect Stability, Binding to MBL, and Enzymatic Activity

Steffen Thiel, Martin Kolev, Søren Degn, Rudi Steffensen, Annette G. Hansen, Marieta Ruseva, and Jens C. Jensenius
J Immunol 2009 182: 2939-2947; doi:10.4049/jimmunol.0802053 [Abstract] [Full Text] [PDF]  

Blimp-1/PRDM1 Mediates Transcriptional Suppression of the NLR Gene NLRP12/Monarch-1

Christopher A. Lord, David Savitsky, Raquel Sitcheran, Kathryn Calame, Jo Rae Wright, Jenny Pan-Yun Ting, and Kristi L. Williams
J Immunol 2009 182: 2948-2958; doi:10.4049/jimmunol.0801692 [Abstract] [Full Text] [PDF]  

Promoter Knock-In Mutations Reveal a Role of Mcl-1 in Thymocyte-Positive Selection and Tissue or Cell Lineage-Specific Regulation of Mcl-1 Expression

Chia-Yu Yang, Nai-Hui Lin, Jan-Mou Lee, Ching-Yu Huang, Hsiang-Ju Min, Jeffrey Jong-Young Yen, Nan-Shih Liao, and Hsin-Fang Yang-Yen
J Immunol 2009 182: 2959-2968; doi:10.4049/jimmunol.0803550 [Abstract] [Full Text] [PDF] Data Supplement  

An Unusual Insertion in Jak2 Is Crucial for Kinase Activity and Differentially Affects Cytokine Responses

Claude Haan, Daniela C. Kroy, Stefan Wüller, Ulrike Sommer, Tanja Nöcker, Catherine Rolvering, Iris Behrmann, Peter C. Heinrich, and Serge Haan
J Immunol 2009 182: 2969-2977; doi:10.4049/jimmunol.0800572 [Abstract] [Full Text] [PDF] Data Supplement  

Mapping of a Microbial Protein Domain Involved in Binding and Activation of the TLR2/TLR1 Heterodimer

Shuang Liang, Kavita B. Hosur, Shanyun Lu, Hesham F. Nawar, Benjamin R. Weber, Richard I. Tapping, Terry D. Connell, and George Hajishengallis
J Immunol 2009 182: 2978-2985; doi:10.4049/jimmunol.0803737 [Abstract] [Full Text] [PDF] Data Supplement  

Human SCAMP5, a Novel Secretory Carrier Membrane Protein, Facilitates Calcium-Triggered Cytokine Secretion by Interaction with SNARE Machinery

Chaofeng Han, Taoyong Chen, Mingjin Yang, Nan Li, Haibo Liu, and Xuetao Cao
J Immunol 2009 182: 2986-2996; doi:10.4049/jimmunol.0802002 [Abstract] [Full Text] [PDF] Data Supplement  

Stabilized β-Catenin in Thymic Epithelial Cells Blocks Thymus Development and Function

Saulius Zuklys, Jason Gill, Marcel P. Keller, Mathias Hauri-Hohl, Saule Zhanybekova, Gina Balciunaite, Kyung-Jae Na, Lukas T. Jeker, Katrin Hafen, Noriyuki Tsukamoto, Takashi Amagai, Makoto M. Taketo, Werner Krenger, and Georg A. Holländer
J Immunol 2009 182: 2997-3007; doi:10.4049/jimmunol.0713723 [Abstract] [Full Text] [PDF]  

IMMUNOGENETICS:

Disseminated and Rapidly Fatal Tuberculosis in Mice Bearing a Defective Allele at IFN Regulatory Factor 8

Jean-François Marquis, Ronald LaCourse, Lynn Ryan, Robert J. North, and Philippe Gros
J Immunol 2009 182: 3008-3015; doi:10.4049/jimmunol.0800680 [Abstract] [Full Text] [PDF]  

High Resolution Mapping of Cia3: A Common Arthritis Quantitative Trait Loci in Different Species

Xinhua Yu, Haidong Teng, Andreia Marques, Farahnaz Ashgari, and Saleh M. Ibrahim
J Immunol 2009 182: 3016-3023; doi:10.4049/jimmunol.0803005 [Abstract] [Full Text] [PDF] Data Supplement  

HOST DEFENSE:

Fas Ligand Is Required for the Development of Respiratory Syncytial Virus Vaccine-Enhanced Disease

Matthew R. Olson and Steven M. Varga
J Immunol 2009 182: 3024-3031; doi:10.4049/jimmunol.0803585 [Abstract] [Full Text] [PDF]  

Selective Priming and Expansion of Antigen-Specific Foxp3^–CD4⁺ T Cells during Listeria monocytogenes Infection

James M. Ertelt, Jared H. Rowe, Tanner M. Johanns, Joseph C. Lai, James B. McLachlan, and Sing Sing Way
J Immunol 2009 182: 3032-3038; doi:10.4049/jimmunol.0803402 [Abstract] [Full Text] [PDF]  

IL-17 Promotes Progression of Cutaneous Leishmaniasis in Susceptible Mice

Susanna Lopez Kostka, Stephanie Dinges, Klaus Griewank, Yoichiro Iwakura, Mark C. Udey, and Esther von Stebut
J Immunol 2009 182: 3039-3046; doi:10.4049/jimmunol.0713598 [Abstract] [Full Text] [PDF]  

Reciprocal Interactions between Commensal Bacteria and Intraepithelial Lymphocytes during Mucosal Injury

Anisa S. Ismail, Cassie L. Behrendt, and Lora V. Hooper
J Immunol 2009 182: 3047-3054; doi:10.4049/jimmunol.0802705 [Abstract] [Full Text] [PDF] Data Supplement  

Rapid Dendritic Cell Mobilization to the Large Intestinal Epithelium Is Associated with Resistance to Trichuris muris Infection

Sheena M. Cruickshank, Matthew L. Deschoolmeester, Marcus Svensson, Gareth Howell, Aikaterini Bazakou, Larisa Logunova, Matthew C. Little, Nicholas English, Matthias Mack, Richard K. Grencis, Kathryn J. Else, and Simon R. Carding
J Immunol 2009 182: 3055-3062; doi:10.4049/jimmunol.0802749 [Abstract] [Full Text] [PDF]  

Vaccinia Virus-Based Multivalent H5N1 Avian Influenza Vaccines Adjuvanted with IL-15 Confer Sterile Cross-Clade Protection in Mice

Leo L. M. Poon, Y. H. Connie Leung, John M. Nicholls, Pin-Yu Perera, Jack H. Lichy, Masafumi Yamamoto, Thomas A. Waldmann, J. S. Malik Peiris, and Liyanage P. Perera
J Immunol 2009 182: 3063-3071; doi:10.4049/jimmunol.0803467 [Abstract] [Full Text] [PDF]  

Subversion of Pulmonary Dendritic Cell Function by Paramyxovirus Infections

Antonieta Guerrero-Plata, Deepthi Kolli, Chao Hong, Antonella Casola, and Roberto P. Garofalo
J Immunol 2009 182: 3072-3083; doi:10.4049/jimmunol.0802262 [Abstract] [Full Text] [PDF]  

Alternatively Activated Macrophages Elicited by Helminth Infection Can Be Reprogrammed to Enable Microbial Killing

Katie J. Mylonas, Meera G. Nair, Lidia Prieto-Lafuente, Daniel Paape, and Judith E. Allen
J Immunol 2009 182: 3084-3094; doi:10.4049/jimmunol.0803463 [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Acute, but Not Resolved, Influenza A Infection Enhances Susceptibility to House Dust Mite-Induced Allergic Disease

Amal A. Al-Garawi, Ramzi Fattouh, Tina D. Walker, Erin B. Jamula, Fernando Botelho, Susanna Goncharova, Jennifer Reed, Martin R. Stampfli, Paul M. O'Byrne, Anthony J. Coyle, and Manel Jordana
J Immunol 2009 182: 3095-3104; doi:10.4049/jimmunol.0802837 [Abstract] [Full Text] [PDF] Data Supplement  

Tumor-Specific Bacteriophages Induce Tumor Destruction through Activation of Tumor-Associated Macrophages

Fredrik Eriksson, Panagiotis Tsagozis, Kajsa Lundberg, Roham Parsa, Sara M. Mangsbo, Mats A. A. Persson, Robert A. Harris, and Pavel Pisa
J Immunol 2009 182: 3105-3111; doi:10.4049/jimmunol.0800224 [Abstract] [Full Text] [PDF] Data Supplement  

Genome-Wide Comparison between IL-17A- and IL-17F-Induced Effects in Human Rheumatoid Arthritis Synoviocytes

Saloua Zrioual, René Ecochard, Anne Tournadre, Vanina Lenief, Marie-Angélique Cazalis, and Pierre Miossec
J Immunol 2009 182: 3112-3120; doi:10.4049/jimmunol.0801967 [Abstract] [Full Text] [PDF] Data Supplement  

Inhibition of CCR6 Function Reduces the Severity of Experimental Autoimmune Encephalomyelitis via Effects on the Priming Phase of the Immune Response

Adrian Liston, Rachel E. Kohler, Scott Townley, Sarah Haylock-Jacobs, Iain Comerford, Adriana C. Caon, Julie Webster, Jodie M. Harrison, Jeremy Swann, Ian Clark-Lewis, Heinrich Korner, and Shaun R. McColl
J Immunol 2009 182: 3121-3130; doi:10.4049/jimmunol.0713169 [Abstract] [Full Text] [PDF]  

NF-B1 p105 Regulates T Cell Homeostasis and Prevents Chronic Inflammation

Mikyoung Chang, Andrew J. Lee, Leo Fitzpatrick, Minying Zhang, and Shao-Cong Sun
J Immunol 2009 182: 3131-3138; doi:10.4049/jimmunol.0803637 [Abstract] [Full Text] [PDF]  

Herpesvirus Entry Mediator-Ig Treatment during Immunization Aggravates Rheumatoid Arthritis in the Collagen-Induced Arthritis Model

Matthias Pierer, Anett Schulz, Manuela Rossol, Eva Kendzia, Diego Kyburz, Holm Haentzschel, Christoph Baerwald, and Ulf Wagner
J Immunol 2009 182: 3139-3145; doi:10.4049/jimmunol.0713715 [Abstract] [Full Text] [PDF] Data Supplement  

Blockade of Indoleamine 2,3-Dioxygenase Protects Mice against Lipopolysaccharide-Induced Endotoxin Shock

In Duk Jung, Min-Goo Lee, Jeong Hyun Chang, Jun Sik Lee, Young-Il Jeong, Chang-Min Lee, Won Sun Park, Jin Han, Su-Kil Seo, Sang Yong Lee, and Yeong-Min Park
J Immunol 2009 182: 3146-3154; doi:10.4049/jimmunol.0803104 [Abstract] [Full Text] [PDF] Data Supplement  

Macrophage Oxygen Sensing Modulates Antigen Presentation and Phagocytic Functions Involving IFN- Production through the HIF-1 Transcription Factor

Bárbara Acosta-Iborra, Ainara Elorza, Isabel M. Olazabal, Noa B. Martín-Cofreces, Silvia Martin-Puig, Marta Miró, María J. Calzada, Julián Aragonés, Francisco Sánchez-Madrid, and Manuel O. Landázuri
J Immunol 2009 182: 3155-3164; doi:10.4049/jimmunol.0801710 [Abstract] [Full Text] [PDF] Data Supplement  

Differential Migration of Epidermal and Dermal Dendritic Cells during Skin Infection

Liv Eidsmo, Rhys Allan, Irina Caminschi, Nico van Rooijen, William R. Heath, and Francis R. Carbone
J Immunol 2009 182: 3165-3172; doi:10.4049/jimmunol.0802950 [Abstract] [Full Text] [PDF]  

Activation of Inflammasomes Requires Intracellular Redistribution of the Apoptotic Speck-Like Protein Containing a Caspase Recruitment Domain

Nicole B. Bryan, Andrea Dorfleutner, Yon Rojanasakul, and Christian Stehlik
J Immunol 2009 182: 3173-3182; doi:10.4049/jimmunol.0802367 [Abstract] [Full Text] [PDF]  

Anti-Inflammatory Role of IL-17 in Experimental Autoimmune Uveitis

Yan Ke, Ke Liu, Guo-Qiang Huang, Yan Cui, Henry J. Kaplan, Hui Shao, and Deming Sun
J Immunol 2009 182: 3183-3190; doi:10.4049/jimmunol.0802487 [Abstract] [Full Text] [PDF]  

Role of Tim-3/Galectin-9 Inhibitory Interaction in Viral-Induced Immunopathology: Shifting the Balance toward Regulators

Sharvan Sehrawat, Amol Suryawanshi, Mitsuomi Hirashima, and Barry T. Rouse
J Immunol 2009 182: 3191-3201; doi:10.4049/jimmunol.0803673 [Abstract] [Full Text] [PDF]  

Induction of IDO by Bacille Calmette-Guérin Is Responsible for Development of Murine Depressive-Like Behavior

Jason C. O'Connor, Marcus A. Lawson, Caroline André, Eileen M. Briley, Sandra S. Szegedi, Jacques Lestage, Nathalie Castanon, Miles Herkenham, Robert Dantzer, and Keith W. Kelley
J Immunol 2009 182: 3202-3212; doi:10.4049/jimmunol.0802722 [Abstract] [Full Text] [PDF]  

ELR-CXC Chemokine Receptor Antagonism Targets Inflammatory Responses at Multiple Levels

Xixing Zhao, Jennifer R. Town, Fang Li, Xiaobei Zhang, Donald W. Cockcroft, and John R. Gordon
J Immunol 2009 182: 3213-3222; doi:10.4049/jimmunol.0800551 [Abstract] [Full Text] [PDF]  

Acute Changes in Dietary -3 and -6 Polyunsaturated Fatty Acids Have a Pronounced Impact on Survival following Ischemic Renal Injury and Formation of Renoprotective Docosahexaenoic Acid-Derived Protectin D1

Iram R. Hassan and Karsten Gronert
J Immunol 2009 182: 3223-3232; doi:10.4049/jimmunol.0802064 [Abstract] [Full Text] [PDF]  

c-Abl Kinase Is Required for β₂ Integrin-Mediated Neutrophil Adhesion

Lingling Cui, Cuixia Chen, Ting Xu, Juechao Zhang, Xin Shang, Jixian Luo, Liang Chen, Xueqing Ba, and Xianlu Zeng
J Immunol 2009 182: 3233-3242; doi:10.4049/jimmunol.0802621 [Abstract] [Full Text] [PDF] Data Supplement  

Involvement of Proton-Sensing TDAG8 in Extracellular Acidification-Induced Inhibition of Proinflammatory Cytokine Production in Peritoneal Macrophages

Chihiro Mogi, Masayuki Tobo, Hideaki Tomura, Naoya Murata, Xiao-dong He, Koichi Sato, Takao Kimura, Tamotsu Ishizuka, Takehiko Sasaki, Takashi Sato, Yasuyuki Kihara, Satoshi Ishii, Akihiro Harada, and Fumikazu Okajima
J Immunol 2009 182: 3243-3251; doi:10.4049/jimmunol.0803466 [Abstract] [Full Text] [PDF]  

The Development of Airway Hyperreactivity in T-bet-Deficient Mice Requires CD1d-Restricted NKT Cells

Hye Young Kim, Muriel Pichavant, Ponpan Matangkasombut, Youngil I. Koh, Paul B. Savage, Rosemarie H. DeKruyff, and Dale T. Umetsu
J Immunol 2009 182: 3252-3261; doi:10.4049/jimmunol.0803339 [Abstract] [Full Text] [PDF]  

Nonresolving Inflammation in gp91^phox–/– Mice, a Model of Human Chronic Granulomatous Disease, Has Lower Adenosine and Cyclic Adenosine 5'-Monophosphate

Ravindra Rajakariar, Justine Newson, Edwin K. Jackson, Precilla Sawmynaden, Andrew Smith, Farooq Rahman, Muhammad M. Yaqoob, and Derek W. Gilroy
J Immunol 2009 182: 3262-3269; doi:10.4049/jimmunol.0801739 [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Peripheral T Cell Functions Correlate with the Severity of Chronic Obstructive Pulmonary Disease

Xuehai Zhu, Aneal S. Gadgil, Rachel Givelber, M. Patricia George, Michael W. Stoner, Frank C. Sciurba, and Steven R. Duncan
J Immunol 2009 182: 3270-3277; doi:10.4049/jimmunol.0802622 [Abstract] [Full Text] [PDF]  

End-Organ Damage in a Mouse Model of Fulminant Liver Inflammation Requires CD4⁺ T Cell Production of IFN- but Is Independent of Fas

Richard T. Robinson, Jing Wang, James G. Cripps, Michael W. Milks, Kathryn A. English, Todd A. Pearson, and James D. Gorham
J Immunol 2009 182: 3278-3284; doi:10.4049/jimmunol.0803417 [Abstract] [Full Text] [PDF]  

Th1/Th2 Patterns and Balance in Cytokine Production in the Parents and Infants of a Large Birth Cohort

Marilyn Halonen, I. Carla Lohman, Debra A. Stern, Amber Spangenberg, Dayna Anderson, Sara Mobley, Kathy Ciano, Michael Peck, and Anne L. Wright
J Immunol 2009 182: 3285-3293; doi:10.4049/jimmunol.0711996 [Abstract] [Full Text] [PDF] Data Supplement  

Membrane Estrogen Receptor Regulates Experimental Autoimmune Encephalomyelitis through Up-regulation of Programmed Death 1

Chunhe Wang, Babak Dehghani, Yuexin Li, Laurie J. Kaler, Thomas Proctor, Arthur A. Vandenbark, and Halina Offner
J Immunol 2009 182: 3294-3303; doi:10.4049/jimmunol.0803205 [Abstract] [Full Text] [PDF]  

The Cellular Amount of the Common -Chain Influences Spontaneous or Induced Cell Proliferation

Stefania Amorosi, Ilaria Russo, Giada Amodio, Corrado Garbi, Laura Vitiello, Loredana Palamaro, Marsilio Adriani, Ilaria Vigliano, and Claudio Pignata
J Immunol 2009 182: 3304-3309; doi:10.4049/jimmunol.0802400 [Abstract] [Full Text] [PDF] Data Supplement  

The Microenvironment of Germ Cell Tumors Harbors a Prominent Antigen-Driven Humoral Response

Simon N. Willis, Scott S. Mallozzi, Scott J. Rodig, Katherine M. Cronk, Shannon L. McArdel, Tyler Caron, Geraldine S. Pinkus, Laura Lovato, Kimberly L. Shampain, David E. Anderson, Richard C. E. Anderson, Jeffrey N. Bruce, and Kevin C. O’Connor
J Immunol 2009 182: 3310-3317; doi:10.4049/jimmunol.0803424 [Abstract] [Full Text] [PDF]  

The TLR9 Ligand CpG Promotes the Acquisition of Plasmodium falciparum-Specific Memory B Cells in Malaria-Naive Individuals

Peter D. Crompton, Marko Mircetic, Greta Weiss, Amy Baughman, Chiung-Yu Huang, David J. Topham, John J. Treanor, Iñaki Sanz, F. Eun-Hyung Lee, Anna P. Durbin, Kazutoyo Miura, David L. Narum, Ruth D. Ellis, Elissa Malkin, Gregory E. D. Mullen, Louis H. Miller, Laura B. Martin, and Susan K. Pierce
J Immunol 2009 182: 3318-3326; doi:10.4049/jimmunol.0803596 [Abstract] [Full Text] [PDF]  

CORRECTIONS:

Induction of HIV transcription by Nef involves Lck activation and protein kinase C raft recruitment leading to activation of ERK1/2 but not NFB

V. Witte, B. Laffert, P. Gintschel, E. Krautkrämer, K. Blume, O. T. Fackler, and A. S. Baur
J Immunol 2009 182: 3327; doi:10.4049/jimmunol.0990009 [Full Text] [PDF]  

Graft-versus-host disease prevents the maturation of plasmacytoid dendritic cells

T. Banovic, K. A. Markey, R. D. Kuns, S. D. Olver, N. C. Raffelt, A. L. Don, M. A. Degli-Esposti, C. R. Engwerda, K. P. A. MacDonald, and G. R. Hill
J Immunol 2009 182: 3327; doi:10.4049/jimmunol.0990010 [Full Text] [PDF]  

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