IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2009 182: 1777-1778; doi:10.4049/jimmunol.0990004 [Full Text] [PDF] ImmunoCast  

LETTERS TO THE EDITOR:

Comment on "Trafficking of Antigen-Specific CD8⁺ T Lymphocytes to Mucosal Surfaces following Intramuscular Vaccination"

Igor M. Belyakov and Jeffrey D. Ahlers
J Immunol 2009 182: 1779; doi:10.4049/jimmunol.0990002 [Full Text] [PDF]  

Response to Comment on "Trafficking of Antigen-Specific CD8⁺ T Lymphocytes to Mucosal Surfaces following Intramuscular Vaccination"

David R. Kaufman and Dan H. Barouch
J Immunol 2009 182: 1779-1780; doi:10.4049/jimmunol.09-90003 [Full Text] [PDF]  

BRIEF REVIEWS:

IL-21: An Executor of B Cell Fate

Danijela Konforte, Nathalie Simard, and Christopher J. Paige
J Immunol 2009 182: 1781-1787; doi:10.4049/jimmunol.0803009 [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: The Y Chromosome Controls the Age-Dependent Experimental Allergic Encephalomyelitis Sexual Dimorphism in SJL/J Mice

Karen M. Spach, Melissa Blake, Janice Y. Bunn, Ben McElvany, Rajkumar Noubade, Elizabeth P. Blankenhorn, and Cory Teuscher
J Immunol 2009 182: 1789-1793; doi:10.4049/jimmunol.0803200 [Abstract] [Full Text] [PDF] Data Supplement  

Cutting Edge: Phenotypic Characterization and Differentiation of Human CD8⁺ T Cells Producing IL-17

Takaaki Kondo, Hiroshi Takata, Fumichika Matsuki, and Masafumi Takiguchi
J Immunol 2009 182: 1794-1798; doi:10.4049/jimmunol.0801347 [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Down-Regulation of MHC Class II Expression through Inhibition of CIITA Transcription by Lytic Transactivator Zta during Epstein-Barr Virus Reactivation

Dan Li, Lu Qian, Changguo Chen, Ming Shi, Ming Yu, Meiru Hu, Lun Song, Beifen Shen, and Ning Guo
J Immunol 2009 182: 1799-1809; doi:10.4049/jimmunol.0802686 [Abstract] [Full Text] [PDF]  

CDK2 Phosphorylation of Smad2 Disrupts TGF-β Transcriptional Regulation in Resistant Primary Bone Marrow Myeloma Cells

Linda B. Baughn, Maurizio Di Liberto, Ruben Niesvizky, Hearn J. Cho, David Jayabalan, Joseph Lane, Fang Liu, and Selina Chen-Kiang
J Immunol 2009 182: 1810-1817; doi:10.4049/jimmunol.0713726 [Abstract] [Full Text] [PDF]  

Immunosuppressive Myeloid-Derived Suppressor Cells Can Be Converted into Immunogenic APCs with the Help of Activated NKT Cells: An Alternative Cell-Based Antitumor Vaccine

Hyun-Jeong Ko, Jung-Mi Lee, Yeon-Jeong Kim, Yun-Sun Kim, Kyoo-A Lee, and Chang-Yuil Kang
J Immunol 2009 182: 1818-1828; doi:10.4049/jimmunol.0802430 [Abstract] [Full Text] [PDF]  

CD8⁺ T Cell Responses to a Viral Escape Mutant Epitope: Active Suppression via Altered SHP-1 Activity

Frederick J. Schnell, Noah Alberts-Grill, and Brian D. Evavold
J Immunol 2009 182: 1829-1835; doi:10.4049/jimmunol.0801798 [Abstract] [Full Text] [PDF]  

Evolution of Lipopolysaccharide (LPS) Recognition and Signaling: Fish TLR4 Does Not Recognize LPS and Negatively Regulates NF-B Activation

María P. Sepulcre, Francisca Alcaraz-Pérez, Azucena López-Muñoz, Francisco J. Roca, José Meseguer, María L. Cayuela, and Victoriano Mulero
J Immunol 2009 182: 1836-1845; doi:10.4049/jimmunol.0801755 [Abstract] [Full Text] [PDF]  

Role of Invariant NK T Lymphocytes in Immune Responses to CpG Oligodeoxynucleotides

Christophe Paget, Emilie Bialecki, Josette Fontaine, Catherine Vendeville, Thierry Mallevaey, Christelle Faveeuw, and François Trottein
J Immunol 2009 182: 1846-1853; doi:10.4049/jimmunol.0802492 [Abstract] [Full Text] [PDF]  

Human IgA-Inducing Protein from Dendritic Cells Induces IgA Production by Naive IgD⁺ B Cells

Mark A. Endsley, Leo M. Njongmeta, Elisabeth Shell, Matthew W. Ryan, Alexander J. Indrikovs, Seckin Ulualp, Randall M. Goldblum, Waithaka Mwangi, and D. Mark Estes
J Immunol 2009 182: 1854-1859; doi:10.4049/jimmunol.0801973 [Abstract] [Full Text] [PDF]  

TLR2 Engagement on CD8 T Cells Enables Generation of Functional Memory Cells in Response to a Suboptimal TCR Signal

Blandine C. Mercier, Anne Cottalorda, Charles-Antoine Coupet, Jacqueline Marvel, and Nathalie Bonnefoy-Bérard
J Immunol 2009 182: 1860-1867; doi:10.4049/jimmunol.0801167 [Abstract] [Full Text] [PDF] Data Supplement  

Requirement of B Cells for Generating CD4⁺ T Cell Memory

Jason K. Whitmire, Mary S. Asano, Susan M. Kaech, Surojit Sarkar, Lynn G. Hannum, Mark J. Shlomchik, and Rafi Ahmed
J Immunol 2009 182: 1868-1876; doi:10.4049/jimmunol.0802501 [Abstract] [Full Text] [PDF]  

Carbon Monoxide Inhibits TLR-Induced Dendritic Cell Immunogenicity

Séverine Rémy, Philippe Blancou, Laurent Tesson, Virginie Tardif, Régis Brion, Pierre Joseph Royer, Roberto Motterlini, Roberta Foresti, Marion Painchaut, Sylvie Pogu, Marc Gregoire, Jean Marie Bach, Ignacio Anegon, and Christine Chauveau
J Immunol 2009 182: 1877-1884; doi:10.4049/jimmunol.0802436 [Abstract] [Full Text] [PDF] Data Supplement  

LAG-3 Regulates Plasmacytoid Dendritic Cell Homeostasis

Creg J. Workman, Yao Wang, Karim C. El Kasmi, Drew M. Pardoll, Peter J. Murray, Charles G. Drake, and Dario A. A. Vignali
J Immunol 2009 182: 1885-1891; doi:10.4049/jimmunol.0800185 [Abstract] [Full Text] [PDF]  

T Lymphocyte Homeostasis Is Negatively Regulated by β₂-Microglobulin

Jena D. French, Christina L. Roark, Willi K. Born, and Rebecca L. O'Brien
J Immunol 2009 182: 1892-1900; doi:10.4049/jimmunol.0803165 [Abstract] [Full Text] [PDF]  

Human Liver Dendritic Cells Promote T Cell Hyporesponsiveness

Zubin M. Bamboat, Jennifer A. Stableford, George Plitas, Bryan M. Burt, Hoang M. Nguyen, Alexander P. Welles, Mithat Gonen, James W. Young, and Ronald P. DeMatteo
J Immunol 2009 182: 1901-1911; doi:10.4049/jimmunol.0803404 [Abstract] [Full Text] [PDF]  

A Role of IgM Antibodies in Monosodium Urate Crystal Formation and Associated Adjuvanticity

Uliana Kanevets, Karan Sharma, Karen Dresser, and Yan Shi
J Immunol 2009 182: 1912-1918; doi:10.4049/jimmunol.0803777 [Abstract] [Full Text] [PDF]  

Cyclical Expression of EBV Latent Membrane Protein 1 in EBV-Transformed B Cells Underpins Heterogeneity of Epitope Presentation and CD8⁺ T Cell Recognition

Jill M. Brooks, Steven P. Lee, Alison M. Leese, Wendy A. Thomas, Martin Rowe, and Alan B. Rickinson
J Immunol 2009 182: 1919-1928; doi:10.4049/jimmunol.0713607 [Abstract] [Full Text] [PDF]  

The Expression of Heparin-Binding Epidermal Growth Factor-Like Growth Factor by Regulatory Macrophages

Justin P. Edwards, Xia Zhang, and David M. Mosser
J Immunol 2009 182: 1929-1939; doi:10.4049/jimmunol.0802703 [Abstract] [Full Text] [PDF] Data Supplement  

Naive Mouse Macrophages Become Activated following Recognition of L5178Y Lymphoma Cells via Concurrent Ligation of CD40, NKG2D, and CD18 Molecules

Ilia N. Buhtoiarov, Alexander L. Rakhmilevich, Lewis L. Lanier, Erik A. Ranheim, and Paul M. Sondel
J Immunol 2009 182: 1940-1953; doi:10.4049/jimmunol.0800443 [Abstract] [Full Text] [PDF]  

Coronin 1 Is Essential for IgM-Mediated Ca²⁺ Mobilization in B Cells but Dispensable for the Generation of Immune Responses In Vivo

Benoit Combaluzier, Philipp Mueller, Jan Massner, Daniela Finke, and Jean Pieters
J Immunol 2009 182: 1954-1961; doi:10.4049/jimmunol.0801811 [Abstract] [Full Text] [PDF]  

Human CD4⁺ Memory T Cells Are Preferential Targets for Bystander Activation and Apoptosis

Sarah C. Bangs, Dilair Baban, Helen J. Cattan, Chris Ka-Fi Li, Andrew J. McMichael, and Xiao-Ning Xu
J Immunol 2009 182: 1962-1971; doi:10.4049/jimmunol.0802596 [Abstract] [Full Text] [PDF] Data Supplement  

Protein Kinase C- Is Required for NK Cell Activation and In Vivo Control of Tumor Progression

Juan I. Aguiló, Johan Garaude, Julián Pardo, Martín Villalba, and Alberto Anel
J Immunol 2009 182: 1972-1981; doi:10.4049/jimmunol.0801820 [Abstract] [Full Text] [PDF]  

A Defect in Marco Expression Contributes to Systemic Lupus Erythematosus Development via Failure to Clear Apoptotic Cells

Nicola Jane Rogers, Mark Jeffrey Lees, Luisa Gabriel, Eleni Maniati, Sarah Jane Rose, Paul Keith Potter, and Bernard John Morley
J Immunol 2009 182: 1982-1990; doi:10.4049/jimmunol.0801320 [Abstract] [Full Text] [PDF]  

Human B Cell Responses to TLR Ligands Are Differentially Modulated by Myeloid and Plasmacytoid Dendritic Cells

Iyadh Douagi, Cornelia Gujer, Christopher Sundling, William C. Adams, Anna Smed-Sörensen, Robert A. Seder, Gunilla B. Karlsson Hedestam, and Karin Loré
J Immunol 2009 182: 1991-2001; doi:10.4049/jimmunol.0802257 [Abstract] [Full Text] [PDF] Data Supplement  

Allergic Airway Hyperresponsiveness-Enhancing T Cells Develop in Normal Untreated Mice and Fail to Produce IL-4/13, Unlike Th2 and NKT Cells

Niyun Jin, Christina L. Roark, Nobuaki Miyahara, Christian Taube, M. Kemal Aydintug, J. M. Wands, Yafei Huang, Youn-Soo Hahn, Erwin W. Gelfand, Rebecca L. O'Brien, and Willi K. Born
J Immunol 2009 182: 2002-2010; doi:10.4049/jimmunol.0803280 [Abstract] [Full Text] [PDF]  

Intact Bacteria Inhibit the Induction of Humoral Immune Responses to Bacterial-Derived and Heterologous Soluble T Cell-Dependent Antigens

Gouri Chattopadhyay, Quanyi Chen, Jesus Colino, Andrew Lees, and Clifford M. Snapper
J Immunol 2009 182: 2011-2019; doi:10.4049/jimmunol.0802615 [Abstract] [Full Text] [PDF]  

A Kinase-Dead Allele of Lyn Attenuates Autoimmune Disease Normally Associated with Lyn Deficiency

Anne M. Verhagen, Morgan E. Wallace, Ankita Goradia, Sarah A. Jones, Hayley A. Croom, Donald Metcalf, Janelle E. Collinge, Mhairi J. Maxwell, Margaret L. Hibbs, Warren S. Alexander, Douglas J. Hilton, Benjamin T. Kile, and Robyn Starr
J Immunol 2009 182: 2020-2029; doi:10.4049/jimmunol.0803127 [Abstract] [Full Text] [PDF]  

Recovery from Cyclophosphamide-Induced Lymphopenia Results in Expansion of Immature Dendritic Cells Which Can Mediate Enhanced Prime-Boost Vaccination Antitumor Responses In Vivo When Stimulated with the TLR3 Agonist Poly(I:C)

Mohamed L. Salem, C. Marcela Díaz-Montero, Amir A. Al-Khami, Sabry A. El-Naggar, Osama Naga, Alberto J. Montero, Ahmed Khafagy, and David J. Cole
J Immunol 2009 182: 2030-2040; doi:10.4049/jimmunol.0801829 [Abstract] [Full Text] [PDF] Data Supplement  

Myosin-IIA and ICAM-1 Regulate the Interchange between Two Distinct Modes of T Cell Migration

Jordan Jacobelli, F. Chris Bennett, Priya Pandurangi, Aaron J. Tooley, and Matthew F. Krummel
J Immunol 2009 182: 2041-2050; doi:10.4049/jimmunol.0803267 [Abstract] [Full Text] [PDF] Data Supplement  

The Activation of P2X7 Receptor Impairs Lysosomal Functions and Stimulates the Release of Autophagolysosomes in Microglial Cells

Takato Takenouchi, Masaaki Nakai, Yoshifumi Iwamaru, Shuei Sugama, Mitsutoshi Tsukimoto, Masayo Fujita, Jianshe Wei, Akio Sekigawa, Mitsuru Sato, Shuji Kojima, Hiroshi Kitani, and Makoto Hashimoto
J Immunol 2009 182: 2051-2062; doi:10.4049/jimmunol.0802577 [Abstract] [Full Text] [PDF]  

Activation of Mammalian Target of Rapamycin Controls the Loss of TCR in Lupus T Cells through HRES-1/Rab4-Regulated Lysosomal Degradation

David R. Fernandez, Tiffany Telarico, Eduardo Bonilla, Qing Li, Sanjay Banerjee, Frank A. Middleton, Paul E. Phillips, Mary K. Crow, Stefanie Oess, Werner Muller-Esterl, and Andras Perl
J Immunol 2009 182: 2063-2073; doi:10.4049/jimmunol.0803600 [Abstract] [Full Text] [PDF] Data Supplement  

1,25-Dihydroxyvitamin D₃ Is an Autonomous Regulator of the Transcriptional Changes Leading to a Tolerogenic Dendritic Cell Phenotype

Lajos Széles, Gábor Keresztes, Dániel Töröcsik, Zoltán Balajthy, László Krenács, Szilárd Póliska, Andreas Steinmeyer, Ulrich Zuegel, Monika Pruenster, Antal Rot, and László Nagy
J Immunol 2009 182: 2074-2083; doi:10.4049/jimmunol.0803345 [Abstract] [Full Text] [PDF] Data Supplement  

Transglutaminase 2 Is Needed for the Formation of an Efficient Phagocyte Portal in Macrophages Engulfing Apoptotic Cells

Beáta Tóth, Éva Garabuczi, Zsolt Sarang, György Vereb, György Vámosi, Daniel Aeschlimann, Bernadett Blaskó, Bálint Bécsi, Ferenc Erdõdi, Adam Lacy-Hulbert, Ailiang Zhang, Laura Falasca, Raymond B. Birge, Zoltán Balajthy, Gerry Melino, László Fésüs, and Zsuzsa Szondy
J Immunol 2009 182: 2084-2092; doi:10.4049/jimmunol.0803444 [Abstract] [Full Text] [PDF] Data Supplement  

Conditional Inactivation of TACE by a Sox9 Promoter Leads to Osteoporosis and Increased Granulopoiesis via Dysregulation of IL-17 and G-CSF

Keisuke Horiuchi, Tokuhiro Kimura, Takeshi Miyamoto, Kana Miyamoto, Haruhiko Akiyama, Hironari Takaishi, Hideo Morioka, Takashi Nakamura, Yasunori Okada, Carl P. Blobel, and Yoshiaki Toyama
J Immunol 2009 182: 2093-2101; doi:10.4049/jimmunol.0802491 [Abstract] [Full Text] [PDF]  

Intestinal Tolerance Is Converted to Autoimmune Enteritis upon PD-1 Ligand Blockade

Erika D. Reynoso, Kutlu G. Elpek, Loise Francisco, Roderick Bronson, Angélique Bellemare-Pelletier, Arlene H. Sharpe, Gordon J. Freeman, and Shannon J. Turley
J Immunol 2009 182: 2102-2112; doi:10.4049/jimmunol.0802769 [Abstract] [Full Text] [PDF] Data Supplement  

Dendritic Cells and Monocyte/Macrophages That Create the IL-6/APRIL-Rich Lymph Node Microenvironments Where Plasmablasts Mature

Elodie Mohr, Karine Serre, Rudolf A. Manz, Adam F. Cunningham, Mahmood Khan, Deborah L. Hardie, Roger Bird, and Ian C. M. MacLennan
J Immunol 2009 182: 2113-2123; doi:10.4049/jimmunol.0802771 [Abstract] [Full Text] [PDF] Data Supplement  

Unique Phenotype of Human Tonsillar and In Vitro-Induced FOXP3⁺CD8⁺ T Cells

Kerstin Siegmund, Beate Rückert, Nadia Ouaked, Simone Bürgler, Andreas Speiser, Cezmi A. Akdis, and Carsten B. Schmidt-Weber
J Immunol 2009 182: 2124-2130; doi:10.4049/jimmunol.0802271 [Abstract] [Full Text] [PDF] Data Supplement  

The Sequestosome 1/p62 Attenuates Cytokine Gene Expression in Activated Macrophages by Inhibiting IFN Regulatory Factor 8 and TNF Receptor-Associated Factor 6/NF-B Activity

Ji Young Kim and Keiko Ozato
J Immunol 2009 182: 2131-2140; doi:10.4049/jimmunol.0802755 [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

High-Affinity IgE Recognition of a Conformational Epitope of the Major Respiratory Allergen Phl p 2 As Revealed by X-Ray Crystallography

Sivaraman Padavattan, Sabine Flicker, Tilman Schirmer, Christoph Madritsch, Stefanie Randow, Gerald Reese, Stefan Vieths, Christian Lupinek, Christof Ebner, Rudolf Valenta, and Zora Markovic-Housley
J Immunol 2009 182: 2141-2151; doi:10.4049/jimmunol.0803018 [Abstract] [Full Text] [PDF]  

Ignition of p53 Bomb Sensitizes Tumor Cells to Granzyme K-Mediated Cytolysis

Guoqiang Hua, Shuo Wang, Chao Zhong, Peng Xue, and Zusen Fan
J Immunol 2009 182: 2152-2159; doi:10.4049/jimmunol.0802307 [Abstract] [Full Text] [PDF]  

Genetically Encoded Förster Resonance Energy Transfer Sensors for the Conformation of the Src Family Kinase Lck

Wolfgang Paster, Christian Paar, Paul Eckerstorfer, Andrea Jakober, Karel Drbal, Gerhard J. Schütz, Alois Sonnleitner, and Hannes Stockinger
J Immunol 2009 182: 2160-2167; doi:10.4049/jimmunol.0802639 [Abstract] [Full Text] [PDF] Data Supplement  

A Specific Epitope of Protein Inhibitor of Activated STAT3 Is Responsible for the Induction of Apoptosis in Rat Transformed Mast Cells

Zohar Yagil, Gillian Kay, Hovav Nechushtan, and Ehud Razin
J Immunol 2009 182: 2168-2175; doi:10.4049/jimmunol.0803030 [Abstract] [Full Text] [PDF]  

Kinetic of RelA Activation Controls Magnitude of TLR-Mediated IL-12p40 Induction

Konrad A. Bode, Frank Schmitz, Leonardo Vargas, Klaus Heeg, and Alexander H. Dalpke
J Immunol 2009 182: 2176-2184; doi:10.4049/jimmunol.0802560 [Abstract] [Full Text] [PDF]  

Single Nucleotide Changes in the Human I1 and I4 Promoters Underlie Different Transcriptional Responses to CD40

Frank L. Sinquett, Rebecca L. Dryer, Valentina Marcelli, Ameesha Batheja, and Lori R. Covey
J Immunol 2009 182: 2185-2193; doi:10.4049/jimmunol.0802700 [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Mycolactone Inhibits Monocyte Cytokine Production by a Posttranscriptional Mechanism

Rachel E. Simmonds, Ferdinand V. Lali, Tim Smallie, Pamela L. C. Small, and Brian M. Foxwell
J Immunol 2009 182: 2194-2202; doi:10.4049/jimmunol.0802294 [Abstract] [Full Text] [PDF]  

Highly Variable Immune-Response Proteins (185/333) from the Sea Urchin, Strongylocentrotus purpuratus: Proteomic Analysis Identifies Diversity within and between Individuals

Nolwenn M. Dheilly, Sham V. Nair, L. Courtney Smith, and David A. Raftos
J Immunol 2009 182: 2203-2212; doi:10.4049/jimmunol.07012766 [Abstract] [Full Text] [PDF]  

No Significant CTL Cross-Priming by Dendritic Cell-Derived Exosomes during Murine Lymphocytic Choriomeningitis Virus Infection

Ken Coppieters, Ana María Barral, Amy Juedes, Tom Wolfe, Evelyn Rodrigo, Clotilde Théry, Sebastian Amigorena, and Matthias G. von Herrath
J Immunol 2009 182: 2213-2220; doi:10.4049/jimmunol.0802578 [Abstract] [Full Text] [PDF]  

Enhanced In Vivo Growth of Lymphoma Tumors in the Absence of the NK-Activating Receptor NKp46/NCR1

Gili G. Halfteck, Moran Elboim, Chamutal Gur, Hagit Achdout, Hormas Ghadially, and Ofer Mandelboim
J Immunol 2009 182: 2221-2230; doi:10.4049/jimmunol.0801878 [Abstract] [Full Text] [PDF]  

Absence of Mucosal Immunity in the Human Upper Respiratory Tract to the Commensal Bacteria Neisseria lactamica but Not Pathogenic Neisseria meningitidis during the Peak Age of Nasopharyngeal Carriage

Andrew T. Vaughan, Andrew Gorringe, Victoria Davenport, Neil A. Williams, and Robert S. Heyderman
J Immunol 2009 182: 2231-2240; doi:10.4049/jimmunol.0802531 [Abstract] [Full Text] [PDF]  

A Synthetic Carbohydrate-Protein Conjugate Vaccine Candidate against Shigella flexneri 2a Infection

Armelle Phalipon, Myriam Tanguy, Cyrille Grandjean, Catherine Guerreiro, Frédéric Bélot, Dani Cohen, Philippe J. Sansonetti, and Laurence A. Mulard
J Immunol 2009 182: 2241-2247; doi:10.4049/jimmunol.0803141 [Abstract] [Full Text] [PDF] Data Supplement  

TANK-Binding Kinase-1 Plays an Important Role during In Vitro and In Vivo Type I IFN Responses to DNA Virus Infections

Andrea K. Miyahira, Arash Shahangian, Seungmin Hwang, Ren Sun, and Genhong Cheng
J Immunol 2009 182: 2248-2257; doi:10.4049/jimmunol.0802466 [Abstract] [Full Text] [PDF] Data Supplement  

IL-10-Dependent S100A8 Gene Induction in Monocytes/Macrophages by Double-Stranded RNA

Yasumi Endoh, Yuen Ming Chung, Ian A. Clark, Carolyn L. Geczy, and Kenneth Hsu
J Immunol 2009 182: 2258-2268; doi:10.4049/jimmunol.0802683 [Abstract] [Full Text] [PDF]  

Lipopolysaccharide Initiates a Positive Feedback of Epidermal Growth Factor Receptor Signaling by Prostaglandin E₂ in Human Biliary Carcinoma Cells

Laetitia Finzi, Matt X. G. Shao, François Paye, Chantal Housset, and Jay A. Nadel
J Immunol 2009 182: 2269-2276; doi:10.4049/jimmunol.0801768 [Abstract] [Full Text] [PDF]  

Immune Reconstitution during Pneumocystis Lung Infection: Disruption of Surfactant Component Expression and Function by S-Nitrosylation

Elena N. Atochina-Vasserman, Andrew J. Gow, Helen Abramova, Chang-Jiang Guo, Yaniv Tomer, Angela M. Preston, James M. Beck, and Michael F. Beers
J Immunol 2009 182: 2277-2287; doi:10.4049/jimmunol.0802775 [Abstract] [Full Text] [PDF]  

Trypanosoma cruzi Triggers an Early Type I IFN Response In Vivo at the Site of Intradermal Infection

Anne-Danielle C. Chessler, Meera Unnikrishnan, Amy K. Bei, Johanna P. Daily, and Barbara A. Burleigh
J Immunol 2009 182: 2288-2296; doi:10.4049/jimmunol.0800621 [Abstract] [Full Text] [PDF] Data Supplement  

Local Type I IFN Receptor Signaling Protects against Virus Spread within the Central Nervous System

Claudia N. Detje, Thomas Meyer, Hauke Schmidt, Dorothea Kreuz, John K. Rose, Ingo Bechmann, Marco Prinz, and Ulrich Kalinke
J Immunol 2009 182: 2297-2304; doi:10.4049/jimmunol.0800596 [Abstract] [Full Text] [PDF]  

Innate Immunity Mediated by MyD88 Signal Is Not Essential for Induction of Lipopolysaccharide-Specific B Cell Responses but Is Indispensable for Protection against Salmonella enterica serovar Typhimurium infection

Hyun-Jeong Ko, Jin-Young Yang, Doo-Hee Shim, Hyungjun Yang, Sung-Moo Park, Roy Curtiss, III, and Mi-Na Kweon
J Immunol 2009 182: 2305-2312; doi:10.4049/jimmunol.0801980 [Abstract] [Full Text] [PDF]  

Specific Targeting of the EBV Lytic Phase Protein BNLF2a to the Transporter Associated with Antigen Processing Results in Impairment of HLA Class I-Restricted Antigen Presentation

Daniëlle Horst, Daphne van Leeuwen, Nathan P. Croft, Malgorzata A. Garstka, Andrew D. Hislop, Elisabeth Kremmer, Alan B. Rickinson, Emmanuel J. H. J. Wiertz, and Maaike E. Ressing
J Immunol 2009 182: 2313-2324; doi:10.4049/jimmunol.0803218 [Abstract] [Full Text] [PDF]  

Macrophage NADPH Oxidase Flavocytochrome b Localizes to the Plasma Membrane and Rab11-Positive Recycling Endosomes

Amy-Jo Casbon, Lee-Ann H. Allen, Kenneth W. Dunn, and Mary C. Dinauer
J Immunol 2009 182: 2325-2339; doi:10.4049/jimmunol.0803476 [Abstract] [Full Text] [PDF] Data Supplement  

Regulatory T Cells: A Role in the Control of Helminth-Driven Intestinal Pathology and Worm Survival

Riccardo D'Elia, Jerzy M. Behnke, Janette E. Bradley, and Kathryn J. Else
J Immunol 2009 182: 2340-2348; doi:10.4049/jimmunol.0802767 [Abstract] [Full Text] [PDF]  

INFLAMMATION:

CREB Mediates Prostaglandin F₂-Induced MUC5AC Overexpression

Wen-Cheng Chung, Seung-Hee Ryu, Hongxia Sun, Darryl C. Zeldin, and Ja Seok Koo
J Immunol 2009 182: 2349-2356; doi:10.4049/jimmunol.0713637 [Abstract] [Full Text] [PDF]  

Resistin-Like Molecule Decreases Glucose Tolerance during Intestinal Inflammation

Ariel Munitz, Luqman Seidu, Eric T. Cole, Richard Ahrens, Simon P. Hogan, and Marc E. Rothenberg
J Immunol 2009 182: 2357-2363; doi:10.4049/jimmunol.0803130 [Abstract] [Full Text] [PDF]  

Cytolysins Augment Superantigen Penetration of Stratified Mucosa

Amanda J. Brosnahan, Mary J. Mantz, Christopher A. Squier, Marnie L. Peterson, and Patrick M. Schlievert
J Immunol 2009 182: 2364-2373; doi:10.4049/jimmunol.0803283 [Abstract] [Full Text] [PDF]  

The Ubiquitin Ligase c-Cbl Down-Regulates FcRIIa Activation in Human Neutrophils

Louis Marois, Myriam Vaillancourt, Sébastien Marois, Sophie Proulx, Guillaume Paré, Emmanuelle Rollet-Labelle, and Paul H. Naccache
J Immunol 2009 182: 2374-2384; doi:10.4049/jimmunol.0801420 [Abstract] [Full Text] [PDF]  

Activation of Rho Kinase Isoforms in Lung Endothelial Cells during Inflammation

Phyllus Y. Mong and Qin Wang
J Immunol 2009 182: 2385-2394; doi:10.4049/jimmunol.0802811 [Abstract] [Full Text] [PDF]  

Critical Role of Apoptotic Speck Protein Containing a Caspase Recruitment Domain (ASC) and NLRP3 in Causing Necrosis and ASC Speck Formation Induced by Porphyromonas gingivalis in Human Cells

Max Tze-Han Huang, Debra J. Taxman, Elizabeth A. Holley-Guthrie, Chris B. Moore, Stephen B. Willingham, Victoria Madden, Rebecca Keyser Parsons, Gerald L. Featherstone, Roland R. Arnold, Brian P. O'Connor, and Jenny Pan-Yun Ting
J Immunol 2009 182: 2395-2404; doi:10.4049/jimmunol.0800909 [Abstract] [Full Text] [PDF]  

Hyporesponsiveness of Intestinal Dendritic Cells to TLR Stimulation Is Limited to TLR4

Vuk Cerovic, Christopher D. Jenkins, Andrew G. C. Barnes, Simon W. F. Milling, G. Gordon MacPherson, and Linda S. Klavinskis
J Immunol 2009 182: 2405-2415; doi:10.4049/jimmunol.0802318 [Abstract] [Full Text] [PDF] Data Supplement  

IgE Influences the Number and Function of Mature Mast Cells, but Not Progenitor Recruitment in Allergic Pulmonary Inflammation

Clinton B. Mathias, Eva-Jasmin Freyschmidt, Benjamin Caplan, Tatiana Jones, Dimitri Poddighe, Wei Xing, Krista L. Harrison, Michael F. Gurish, and Hans C. Oettgen
J Immunol 2009 182: 2416-2424; doi:10.4049/jimmunol.0801569 [Abstract] [Full Text] [PDF]  

Blocking Development of a CD8⁺ T Cell Response by Targeting Lymphatic Recruitment of APC

Denise Teoh, Louise A. Johnson, Tomas Hanke, Andrew J. McMichael, and David G. Jackson
J Immunol 2009 182: 2425-2431; doi:10.4049/jimmunol.0803661 [Abstract] [Full Text] [PDF] Data Supplement  

Human Basophils Secrete IL-3: Evidence of Autocrine Priming for Phenotypic and Functional Responses in Allergic Disease

John T. Schroeder, Kristin L. Chichester, and Anja P. Bieneman
J Immunol 2009 182: 2432-2438; doi:10.4049/jimmunol.0801782 [Abstract] [Full Text] [PDF]  

TNF-Like Weak Inducer of Apoptosis (TWEAK) Activates Proinflammatory Signaling Pathways and Gene Expression through the Activation of TGF-β-Activated Kinase 1

Mukesh Kumar, Denys Y. Makonchuk, Hong Li, Ashwani Mittal, and Ashok Kumar
J Immunol 2009 182: 2439-2448; doi:10.4049/jimmunol.0803357 [Abstract] [Full Text] [PDF]  

Regulation of Mature ADAM17 by Redox Agents for L-Selectin Shedding

Yue Wang, Amy H. Herrera, Ying Li, Kiran K. Belani, and Bruce Walcheck
J Immunol 2009 182: 2449-2457; doi:10.4049/jimmunol.0802770 [Abstract] [Full Text] [PDF]  

Bacterial Endotoxin Induces the Release of High Mobility Group Box 1 via the IFN-β Signaling Pathway

Ju-Hyun Kim, Seon-Ju Kim, Im-Soon Lee, Myung-Shik Lee, Satoshi Uematsu, Shizuo Akira, and Kwon Ik Oh
J Immunol 2009 182: 2458-2466; doi:10.4049/jimmunol.0801364 [Abstract] [Full Text] [PDF]  

The Role of Hepatic Invariant NKT Cells in Systemic/Local Inflammation and Mortality during Polymicrobial Septic Shock

Caroline K. Hu, Fabienne Venet, David S. Heffernan, Yvonne L. Wang, Brian Horner, Xin Huang, Chun-Shiang Chung, Stephen H. Gregory, and Alfred Ayala
J Immunol 2009 182: 2467-2475; doi:10.4049/jimmunol.0801463 [Abstract] [Full Text] [PDF]  

Lactate Boosts TLR4 Signaling and NF-B Pathway-Mediated Gene Transcription in Macrophages via Monocarboxylate Transporters and MD-2 Up-Regulation

Devadoss J. Samuvel, Kamala P. Sundararaj, Alena Nareika, Maria F. Lopes-Virella, and Yan Huang
J Immunol 2009 182: 2476-2484; doi:10.4049/jimmunol.0802059 [Abstract] [Full Text] [PDF]  

Plasma Osteopontin Modulates Chronic Restraint Stress-Induced Thymus Atrophy by Regulating Stress Hormones: Inhibition by an Anti-Osteopontin Monoclonal Antibody

Kathryn X. Wang, Yufang F. Shi, Yacov Ron, Christian C. Kazanecki, and David T. Denhardt
J Immunol 2009 182: 2485-2491; doi:10.4049/jimmunol.0803023 [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

A Phase I-II Study of -Galactosylceramide-Pulsed IL-2/GM-CSF-Cultured Peripheral Blood Mononuclear Cells in Patients with Advanced and Recurrent Non-Small Cell Lung Cancer

Shinichiro Motohashi, Kaoru Nagato, Naoki Kunii, Heizaburo Yamamoto, Kazuki Yamasaki, Kohsuke Okita, Hideki Hanaoka, Naomi Shimizu, Makoto Suzuki, Ichiro Yoshino, Masaru Taniguchi, Takehiko Fujisawa, and Toshinori Nakayama
J Immunol 2009 182: 2492-2501; doi:10.4049/jimmunol.0800126 [Abstract] [Full Text] [PDF]  

Asthma-Related Environmental Fungus, Alternaria, Activates Dendritic Cells and Produces Potent Th2 Adjuvant Activity

Takao Kobayashi, Koji Iijima, Suresh Radhakrishnan, Vinay Mehta, Robert Vassallo, Christopher B. Lawrence, Jong-Chol Cyong, Larry R. Pease, Katsuji Oguchi, and Hirohito Kita
J Immunol 2009 182: 2502-2510; doi:10.4049/jimmunol.0802773 [Abstract] [Full Text] [PDF]  

Herpesvirus Seropositivity in Childhood Associates with Decreased Monocyte-Induced NK Cell IFN- Production

Shanie Saghafian-Hedengren, Yvonne Sundström, Ebba Sohlberg, Caroline Nilsson, Annika Linde, Marita Troye-Blomberg, Louise Berg, and Eva Sverremark-Ekström
J Immunol 2009 182: 2511-2517; doi:10.4049/jimmunol.0801699 [Abstract] [Full Text] [PDF]  

Synergistic Induction of Inflammation by Bacterial Products Lipopolysaccharide and fMLP: An Important Microbial Pathogenic Mechanism

Ling-Yu Chen, Warren W. Pan, Miao Chen, Jain-Dong Li, Wei Liu, Guoqiang Chen, Shuang Huang, Thomas J. Papadimos, and Zhixing K. Pan
J Immunol 2009 182: 2518-2524; doi:10.4049/jimmunol.0713933 [Abstract] [Full Text] [PDF]  

IFN-β Impairs Superoxide-Dependent Parasite Killing in Human Macrophages: Evidence for a Deleterious Role of SOD1 in Cutaneous Leishmaniasis

Ricardo Khouri, André Bafica, Maria da Purificação Pereira Silva, Almerio Noronha, Jean-Pierre Kolb, Juana Wietzerbin, Aldina Barral, Manoel Barral-Netto, and Johan Van Weyenbergh
J Immunol 2009 182: 2525-2531; doi:10.4049/jimmunol.0802860 [Abstract] [Full Text] [PDF]  

Accelerated Pathological and Clinical Nephritis in Systemic Lupus Erythematosus-Prone New Zealand Mixed 2328 Mice Doubly Deficient in TNF Receptor 1 and TNF Receptor 2 via a Th17-Associated Pathway

Noam Jacob, Haitao Yang, Luminita Pricop, Yi Liu, Xiaoni Gao, Song Guo Zheng, Juhua Wang, Hua-Xin Gao, Chaim Putterman, Michael N. Koss, William Stohl, and Chaim O. Jacob
J Immunol 2009 182: 2532-2541; doi:10.4049/jimmunol.0802948 [Abstract] [Full Text] [PDF] Data Supplement  

Human Basophils Express the Glycosylphosphatidylinositol-Anchored Low-Affinity IgG Receptor FcRIIIB (CD16B)

Nihad Meknache, Friederike Jönsson, Jérôme Laurent, Marie-Thérèse Guinnepain, and Marc Daëron
J Immunol 2009 182: 2542-2550; doi:10.4049/jimmunol.0801665 [Abstract] [Full Text] [PDF]  

CORRECTIONS:

Uncoupling the roles of HLA-DRB1 and HLA-DRB5 genes in multiple sclerosis

S. J. Caillier, F. Briggs, B. A. C. Cree, S. E. Baranzini, M. Fernandez-Viña, P. P. Ramsay, O. Khan, W. Royal, III, S. L. Hauser, L. F. Barcellos, and J. R. Oksenberg
J Immunol 2009 182: 2551; doi:10.4049/jimmunol.0990001 [Full Text] [PDF]  

Lipoproteins are critical TLR2 activating toxins in group B streptococcal sepsis

P. Henneke, S. Dramsi, G. Mancuso, K. Chraibi, E. Pellegrini, C. Theilacker, J. Hübner, S. Santos-Sierra, G. Teti, D. T. Golenbock, C. Poyart, and P. Trieu-Cuot
J Immunol 2009 182: 2551; doi:10.4049/jimmunol.0990005 [Full Text] [PDF]  

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