IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2009 182: 7329-7330; doi:10.4049/jimmunol.0990041 [Full Text] [PDF] ImmunoCast  

BRIEF REVIEWS:

New Insights into the Molecular Basis of T Cell Anergy: Anergy Factors, Avoidance Sensors, and Epigenetic Imprinting

Andrew D. Wells
J Immunol 2009 182: 7331-7341; doi:10.4049/jimmunol.0803917 [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: Primary and Secondary Effects of CD19 Deficiency on Cells of the Marginal Zone

Yuying You, Hong Zhao, Yue Wang, and Robert H. Carter
J Immunol 2009 182: 7343-7347; doi:10.4049/jimmunol.0804295 [Abstract] [Full Text] [PDF] Data Supplement  

Cutting Edge: Intraepithelial Lymphocytes of the Small Intestine Are Not Biased toward Thymic Antigens

Kirk D. C. Jensen, Sunny Shin, and Yueh-hsiu Chien
J Immunol 2009 182: 7348-7351; doi:10.4049/jimmunol.0900465 [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

IL-10 Deficiency Unleashes an Influenza-Specific Th17 Response and Enhances Survival against High-Dose Challenge

K. Kai McKinstry, Tara M. Strutt, Amanda Buck, Jonathan D. Curtis, John P. Dibble, Gail Huston, Michael Tighe, Hiromasa Hamada, Stewart Sell, Richard W. Dutton, and Susan L. Swain
J Immunol 2009 182: 7353-7363; doi:10.4049/jimmunol.0900657 [Abstract] [Full Text] [PDF] Data Supplement  

Keratinocyte Growth Factor Improves Allogeneic Bone Marrow Engraftment through a CD4⁺Foxp3⁺ Regulatory T Cell-Dependent Mechanism

Marieke Bruinsma, Peter L. van Soest, Pieter J. M. Leenen, Bob Löwenberg, Jan J. Cornelissen, and Eric Braakman
J Immunol 2009 182: 7364-7369; doi:10.4049/jimmunol.0803253 [Abstract] [Full Text] [PDF]  

Wiskott-Aldrich Syndrome Protein Is Required for Homeostasis and Function of Invariant NKT Cells

Alexander Astrakhan, Hans D. Ochs, and David J. Rawlings
J Immunol 2009 182: 7370-7380; doi:10.4049/jimmunol.0804256 [Abstract] [Full Text] [PDF]  

Regulation of T Cell Activation by Notch Ligand, DLL4, Promotes IL-17 Production and Rorc Activation

Sumanta Mukherjee, Matthew A. Schaller, Rupak Neupane, Steven L. Kunkel, and Nicholas W. Lukacs
J Immunol 2009 182: 7381-7388; doi:10.4049/jimmunol.0804322 [Abstract] [Full Text] [PDF]  

Identification and Biochemical Characterization of Human Plasma Soluble IL-7R: Lower Concentrations in HIV-1-Infected Patients

Thierry Rose, Olivier Lambotte, Coralie Pallier, Jean-François Delfraissy, and Jean-Hervé Colle
J Immunol 2009 182: 7389-7397; doi:10.4049/jimmunol.0900190 [Abstract] [Full Text] [PDF] Data Supplement  

IFN- Enhances Peptide Vaccine-Induced CD8⁺ T Cell Numbers, Effector Function, and Antitumor Activity

Andrew G. Sikora, Nina Jaffarzad, Yared Hailemichael, Alexander Gelbard, Spencer W. Stonier, Kimberly S. Schluns, Loredana Frasca, Yanyan Lou, Chengwen Liu, Helen A. Andersson, Patrick Hwu, and Willem W. Overwijk
J Immunol 2009 182: 7398-7407; doi:10.4049/jimmunol.0802982 [Abstract] [Full Text] [PDF]  

Ectodomain Shedding of FLT3 Ligand Is Mediated by TNF- Converting Enzyme

Keisuke Horiuchi, Hideo Morioka, Hironari Takaishi, Haruhiko Akiyama, Carl P. Blobel, and Yoshiaki Toyama
J Immunol 2009 182: 7408-7414; doi:10.4049/jimmunol.0801931 [Abstract] [Full Text] [PDF]  

Modulation of p38 MAPK Activity in Regulatory T Cells after Tolerance with Anti-DNA Ig Peptide in (NZB x NZW)F₁ Lupus Mice

Elaine V. Lourenço, Claudio Procaccini, Francesca Ferrera, Noriko Iikuni, Ram P. Singh, Gilberto Filaci, Giuseppe Matarese, Fu-Dong Shi, Ernest Brahn, Bevra H. Hahn, and Antonio La Cava
J Immunol 2009 182: 7415-7421; doi:10.4049/jimmunol.0804214 [Abstract] [Full Text] [PDF]  

The Immunomodulatory Action of Sialostatin L on Dendritic Cells Reveals Its Potential to Interfere with Autoimmunity

Anderson Sá-Nunes, André Bafica, Lis R. Antonelli, Eun Young Choi, Ivo M. B. Francischetti, John F. Andersen, Guo-Ping Shi, Triantafyllos Chavakis, José M. Ribeiro, and Michalis Kotsyfakis
J Immunol 2009 182: 7422-7429; doi:10.4049/jimmunol.0900075 [Abstract] [Full Text] [PDF]  

Cooperation between Mast Cells and Neurons Is Essential for Antigen-Mediated Bronchoconstriction

Jaime M. Cyphert, Martina Kovarova, Irving C. Allen, John M. Hartney, Dennis L. Murphy, Jürgen Wess, and Beverly H. Koller
J Immunol 2009 182: 7430-7439; doi:10.4049/jimmunol.0900039 [Abstract] [Full Text] [PDF] Data Supplement  

Resistance to Celiac Disease in Humanized HLA-DR3-DQ2-Transgenic Mice Expressing Specific Anti-Gliadin CD4⁺ T Cells

Andrea L. de Kauwe, Zhenjun Chen, Robert P. Anderson, Catherine L. Keech, Jason D. Price, Odilia Wijburg, David C. Jackson, Jodi Ladhams, Janette Allison, and James McCluskey
J Immunol 2009 182: 7440-7450; doi:10.4049/jimmunol.0900233 [Abstract] [Full Text] [PDF]  

HSP90 and HSP90β Isoforms Selectively Modulate MHC Class II Antigen Presentation in B Cells

Josetta L. Houlihan, Jennifer J. Metzler, and Janice S. Blum
J Immunol 2009 182: 7451-7458; doi:10.4049/jimmunol.0804296 [Abstract] [Full Text] [PDF]  

The Development and Function of Regulatory B Cells Expressing IL-10 (B10 Cells) Requires Antigen Receptor Diversity and TLR Signals

Koichi Yanaba, Jean-David Bouaziz, Takashi Matsushita, Takeshi Tsubata, and Thomas F. Tedder
J Immunol 2009 182: 7459-7472; doi:10.4049/jimmunol.0900270 [Abstract] [Full Text] [PDF]  

B Cell Receptor-Mediated Internalization of Salmonella: A Novel Pathway for Autonomous B Cell Activation and Antibody Production

Yuri Souwer, Alexander Griekspoor, Tineke Jorritsma, Jelle de Wit, Hans Janssen, Jacques Neefjes, and S. Marieke van Ham
J Immunol 2009 182: 7473-7481; doi:10.4049/jimmunol.0802831 [Abstract] [Full Text] [PDF] Data Supplement  

The Bcl-2 Family Antagonist ABT-737 Significantly Inhibits Multiple Animal Models of Autoimmunity

Philip D. Bardwell, Jijie Gu, Donna McCarthy, Craig Wallace, Shaughn Bryant, Christian Goess, Suzanne Mathieu, Chris Grinnell, Jamie Erickson, Saul H. Rosenberg, Annette J. Schwartz, Margaret Hugunin, Edit Tarcsa, Steven W. Elmore, Bradford McRae, Anwar Murtaza, Li Chun Wang, and Tariq Ghayur
J Immunol 2009 182: 7482-7489; doi:10.4049/jimmunol.0802813 [Abstract] [Full Text] [PDF] Data Supplement  

GITR Triggering Induces Expansion of Both Effector and Regulatory CD4⁺ T Cells In Vivo

Ronald W. van Olffen, Nathalie Koning, Klaas P. J. M. van Gisbergen, Felix M. Wensveen, Robert M. Hoek, Louis Boon, Jörg Hamann, Rene A. W. van Lier, and Martijn A. Nolte
J Immunol 2009 182: 7490-7500; doi:10.4049/jimmunol.0802751 [Abstract] [Full Text] [PDF]  

Small Interfering RNA against Transcription Factor STAT6 Inhibits Allergic Airway Inflammation and Hyperreactivity in Mice

Yasemin Darcan-Nicolaisen, Holger Meinicke, Gabriele Fels, Olga Hegend, Annekathrin Haberland, Anja Kühl, Christoph Loddenkemper, Martin Witzenrath, Stefanie Kube, Wolfgang Henke, and Eckard Hamelmann
J Immunol 2009 182: 7501-7508; doi:10.4049/jimmunol.0713433 [Abstract] [Full Text] [PDF]  

The Immunoregulatory Enzyme IDO Paradoxically Drives B Cell-Mediated Autoimmunity

Grant N. Scott, James DuHadaway, Elizabeth Pigott, Natalie Ridge, George C. Prendergast, Alexander J. Muller, and Laura Mandik-Nayak
J Immunol 2009 182: 7509-7517; doi:10.4049/jimmunol.0804328 [Abstract] [Full Text] [PDF]  

Fc Receptor-Like 3 Protein Expressed on IL-2 Nonresponsive Subset of Human Regulatory T Cells

Satoshi Nagata, Tomoko Ise, and Ira Pastan
J Immunol 2009 182: 7518-7526; doi:10.4049/jimmunol.0802230 [Abstract] [Full Text] [PDF] Data Supplement  

Gene Disruption Study Reveals a Nonredundant Role for TRIM21/Ro52 in NF-B-Dependent Cytokine Expression in Fibroblasts

Ryusuke Yoshimi, Tsung-Hsien Chang, Hongsheng Wang, Toru Atsumi, Herbert C. Morse, III, and Keiko Ozato
J Immunol 2009 182: 7527-7538; doi:10.4049/jimmunol.0804121 [Abstract] [Full Text] [PDF] Data Supplement  

Direct Stimulation of tlr5^+/+ CD11c⁺ Cells Is Necessary for the Adjuvant Activity of Flagellin

John T. Bates, Satoshi Uematsu, Shizuo Akira, and Steven B. Mizel
J Immunol 2009 182: 7539-7547; doi:10.4049/jimmunol.0804225 [Abstract] [Full Text] [PDF]  

Altered Expression of 15-Hydroxyprostaglandin Dehydrogenase in Tumor-Infiltrated CD11b Myeloid Cells: A Mechanism for Immune Evasion in Cancer

Evgeniy Eruslanov, Sergei Kaliberov, Irina Daurkin, Lyudmila Kaliberova, Donald Buchsbaum, Johannes Vieweg, and Sergei Kusmartsev
J Immunol 2009 182: 7548-7557; doi:10.4049/jimmunol.0802358 [Abstract] [Full Text] [PDF]  

The T Cell STAT Signaling Network Is Reprogrammed within Hours of Bacteremia via Secondary Signals

Andrew N. Hotson, Jonathan W. Hardy, Matthew B. Hale, Christopher H. Contag, and Garry P. Nolan
J Immunol 2009 182: 7558-7568; doi:10.4049/jimmunol.0803666 [Abstract] [Full Text] [PDF]  

Involvement of CD252 (CD134L) and IL-2 in the Expression of Cytotoxic Proteins in Bacterial- or Viral-Activated Human T Cells

Michael Walch, Silvana K. Rampini, Isabelle Stoeckli, Sonja Latinovic-Golic, Claudia Dumrese, Hanna Sundstrom, Alexander Vogetseder, Joseph Marino, Daniel L. Glauser, Maries van den Broek, Peter Sander, Peter Groscurth, and Urs Ziegler
J Immunol 2009 182: 7569-7579; doi:10.4049/jimmunol.0800296 [Abstract] [Full Text] [PDF]  

Novel Function of CRTH2 in Preventing Apoptosis of Human Th2 Cells through Activation of the Phosphatidylinositol 3-Kinase Pathway

Luzheng Xue, Anna Barrow, and Roy Pettipher
J Immunol 2009 182: 7580-7586; doi:10.4049/jimmunol.0804090 [Abstract] [Full Text] [PDF]  

The C-Type Lectin Clec12A Present on Mouse and Human Dendritic Cells Can Serve as a Target for Antigen Delivery and Enhancement of Antibody Responses

Mireille H. Lahoud, Anna I. Proietto, Fatma Ahmet, Susie Kitsoulis, Liv Eidsmo, Li Wu, Priyanka Sathe, Suzanne Pietersz, Hsuen-Wen Chang, Ian D. Walker, Eugene Maraskovsky, Hal Braley, Andrew M. Lew, Mark D. Wright, William R. Heath, Ken Shortman, and Irina Caminschi
J Immunol 2009 182: 7587-7594; doi:10.4049/jimmunol.0900464 [Abstract] [Full Text] [PDF] Data Supplement  

CXCR4 Expression Functionally Discriminates Centroblasts versus Centrocytes within Human Germinal Center B Cells

Gersende Caron, Simon Le Gallou, Thierry Lamy, Karin Tarte, and Thierry Fest
J Immunol 2009 182: 7595-7602; doi:10.4049/jimmunol.0804272 [Abstract] [Full Text] [PDF] Data Supplement  

Differential Expression of Adenosine A₃ Receptors Controls Adenosine A_2A Receptor-Mediated Inhibition of TLR Responses in Microglia

Céline van der Putten, Ella A. Zuiderwijk-Sick, Linda van Straalen, Eveline D. de Geus, Leonie A. Boven, Ivanela Kondova, Ad P. IJzerman, and Jeffrey J. Bajramovic
J Immunol 2009 182: 7603-7612; doi:10.4049/jimmunol.0803383 [Abstract] [Full Text] [PDF] Data Supplement  

Vaccination with Aβ-Displaying Virus-Like Particles Reduces Soluble and Insoluble Cerebral Aβ and Lowers Plaque Burden in APP Transgenic Mice

Patricia Bach, Jakob-A. Tschäpe, Ferdinand Kopietz, Gundula Braun, Janina K. Baade, Karl-Heinz Wiederhold, Matthias Staufenbiel, Marco Prinz, Thomas Deller, Ulrich Kalinke, Christian J. Buchholz, and Ulrike C. Müller
J Immunol 2009 182: 7613-7624; doi:10.4049/jimmunol.0803366 [Abstract] [Full Text] [PDF]  

Regulation of Th17 Differentiation by Epidermal Fatty Acid-Binding Protein

Bing Li, Joseph M. Reynolds, Robert D. Stout, David A. Bernlohr, and Jill Suttles
J Immunol 2009 182: 7625-7633; doi:10.4049/jimmunol.0804192 [Abstract] [Full Text] [PDF]  

Exclusion of Natural Autoantibody-Producing B Cells from IgG Memory B Cell Compartment during T Cell-Dependent Immune Responses

Agata Matejuk, Michael Beardall, Yang Xu, Qi Tian, Daniel Phillips, Boris Alabyev, Kaiissar Mannoor, and Ching Chen
J Immunol 2009 182: 7634-7643; doi:10.4049/jimmunol.0801562 [Abstract] [Full Text] [PDF]  

Glycolipids Injected into the Skin Are Presented to NKT Cells in the Draining Lymph Node Independently of Migratory Skin Dendritic Cells

Christoph H. Tripp, Florian Sparber, Ian F. Hermans, Nikolaus Romani, and Patrizia Stoitzner
J Immunol 2009 182: 7644-7654; doi:10.4049/jimmunol.0900134 [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Mechanism and Repertoire of ASC-Mediated Gene Expression

Mizuho Hasegawa, Ryu Imamura, Kou Motani, Takumi Nishiuchi, Norihiko Matsumoto, Takeshi Kinoshita, and Takashi Suda
J Immunol 2009 182: 7655-7662; doi:10.4049/jimmunol.0800448 [Abstract] [Full Text] [PDF] Data Supplement  

Engineering Human IgG1 Affinity to Human Neonatal Fc Receptor: Impact of Affinity Improvement on Pharmacokinetics in Primates

Yik Andy Yeung, Maya K. Leabman, Jonathan S. Marvin, Julia Qiu, Camellia W. Adams, Samantha Lien, Melissa A. Starovasnik, and Henry B. Lowman
J Immunol 2009 182: 7663-7671; doi:10.4049/jimmunol.0804182 [Abstract] [Full Text] [PDF]  

Sequential Cooperation of CD2 and CD48 in the Buildup of the Early TCR Signalosome

Arshad Muhammad, Herbert B. Schiller, Florian Forster, Paul Eckerstorfer, Rene Geyeregger, Vladimir Leksa, Gerhard J. Zlabinger, Maria Sibilia, Alois Sonnleitner, Wolfgang Paster, and Hannes Stockinger
J Immunol 2009 182: 7672-7680; doi:10.4049/jimmunol.0800691 [Abstract] [Full Text] [PDF]  

Dok-4 Is a Novel Negative Regulator of T Cell Activation

Audrey Gérard, Marguerite Ghiotto, Camille Fos, Geoffrey Guittard, Daniel Compagno, Anne Galy, Serge Lemay, Daniel Olive, and Jacques A. Nunès
J Immunol 2009 182: 7681-7689; doi:10.4049/jimmunol.0802203 [Abstract] [Full Text] [PDF] Data Supplement  

Identification of an N-Terminal Recognition Site in TLR9 That Contributes to CpG-DNA-Mediated Receptor Activation

Mirjam E. Peter, Andriy V. Kubarenko, Alexander N. R. Weber, and Alexander H. Dalpke
J Immunol 2009 182: 7690-7697; doi:10.4049/jimmunol.0900819 [Abstract] [Full Text] [PDF]  

Regulation of DNA Demethylation during Maturation of CD4⁺ Naive T Cells by the Conserved Noncoding Sequence 1

Kazuhisa Aoki, Noriko Sato, Atsumi Yamaguchi, Osamu Kaminuma, Takumi Hosozawa, and Shoichiro Miyatake
J Immunol 2009 182: 7698-7707; doi:10.4049/jimmunol.0801643 [Abstract] [Full Text] [PDF]  

Analogous Interactions in Initiating Complexes of the Classical and Lectin Pathways of Complement

Anna E. Phillips, Julia Toth, Alister W. Dodds, Umakhanth Venkatraman Girija, Christopher M. Furze, Eleni Pala, Robert B. Sim, Kenneth B. M. Reid, Wilhelm J. Schwaeble, Ralf Schmid, Anthony H. Keeble, and Russell Wallis
J Immunol 2009 182: 7708-7717; doi:10.4049/jimmunol.0900666 [Abstract] [Full Text] [PDF] Data Supplement  

A20 Negatively Regulates T Cell Receptor Signaling to NF-B by Cleaving Malt1 Ubiquitin Chains

Michael Düwel, Verena Welteke, Andrea Oeckinghaus, Mathijs Baens, Bernhard Kloo, Uta Ferch, Bryant G. Darnay, Jürgen Ruland, Peter Marynen, and Daniel Krappmann
J Immunol 2009 182: 7718-7728; doi:10.4049/jimmunol.0803313 [Abstract] [Full Text] [PDF]  

B Cell Receptor-Mediated Sustained c-Rel Activation Facilitates Late Transitional B Cell Survival through Control of B Cell Activating Factor Receptor and NF-B2

Iris Castro, Jacqueline A. Wright, Bazarragchaa Damdinsuren, Kristen L. Hoek, Gianluca Carlesso, Nicholas P. Shinners, Rachel M. Gerstein, Robert T. Woodland, Ranjan Sen, and Wasif N. Khan
J Immunol 2009 182: 7729-7737; doi:10.4049/jimmunol.0803281 [Abstract] [Full Text] [PDF]  

IMMUNOGENETICS:

Genome-Wide Identification of Long Noncoding RNAs in CD8⁺ T Cells

Ken C. Pang, Marcel E. Dinger, Tim R. Mercer, Lorenzo Malquori, Sean M. Grimmond, Weisan Chen, and John S. Mattick
J Immunol 2009 182: 7738-7748; doi:10.4049/jimmunol.0900603 [Abstract] [Full Text] [PDF] Data Supplement  

CD154-CD40 Interactions Are Essential for Thymus-Dependent Antibody Production in Zebrafish: Insights into the Origin of Costimulatory Pathway in Helper T Cell-Regulated Adaptive Immunity in Early Vertebrates

Yong-Feng Gong, Li-Xin Xiang, and Jian-Zhong Shao
J Immunol 2009 182: 7749-7762; doi:10.4049/jimmunol.0804370 [Abstract] [Full Text] [PDF]  

Two MHC Class I Molecules Associated with Elite Control of Immunodeficiency Virus Replication, Mamu-B*08 and HLA-B*2705, Bind Peptides with Sequence Similarity

John T. Loffredo, John Sidney, Alex T. Bean, Dominic R. Beal, Wilfried Bardet, Angela Wahl, Oriana E. Hawkins, Shari Piaskowski, Nancy A. Wilson, William H. Hildebrand, David I. Watkins, and Alessandro Sette
J Immunol 2009 182: 7763-7775; doi:10.4049/jimmunol.0900111 [Abstract] [Full Text] [PDF] Data Supplement  

A Single Nucleotide Polymorphism in Tyk2 Controls Susceptibility to Experimental Allergic Encephalomyelitis

Karen M. Spach, Rajkumar Noubade, Ben McElvany, William F. Hickey, Elizabeth P. Blankenhorn, and Cory Teuscher
J Immunol 2009 182: 7776-7783; doi:10.4049/jimmunol.0900142 [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Bcl-3-Regulated Transcription from Major Immediate-Early Promoter of Human Cytomegalovirus in Monocyte-Derived Macrophages

Kashif Aziz Khan, Alain Coaquette, Christian Davrinche, and Georges Herbein
J Immunol 2009 182: 7784-7794; doi:10.4049/jimmunol.0803800 [Abstract] [Full Text] [PDF]  

Protective Role for Protease-Activated Receptor-2 against Influenza Virus Pathogenesis via an IFN--Dependent Pathway

Khaled Khoufache, Fanny LeBouder, Eric Morello, Fabrice Laurent, Sabine Riffault, Patricia Andrade-Gordon, Severine Boullier, Perrine Rousset, Nathalie Vergnolle, and Béatrice Riteau
J Immunol 2009 182: 7795-7802; doi:10.4049/jimmunol.0803743 [Abstract] [Full Text] [PDF]  

Fetal Exposure to Ethanol Has Long-Term Effects on the Severity of Influenza Virus Infections

Jodi McGill, David K. Meyerholz, Michelle Edsen-Moore, Betty Young, Ruth A. Coleman, Annette J. Schlueter, Thomas J. Waldschmidt, Robert T. Cook, and Kevin L. Legge
J Immunol 2009 182: 7803-7808; doi:10.4049/jimmunol.0803881 [Abstract] [Full Text] [PDF] Data Supplement  

Scabies Mite Inactivated Serine Protease Paralogs Inhibit the Human Complement System

Frida C. Bergström, Simone Reynolds, Masego Johnstone, Robert N. Pike, Ashley M. Buckle, David J. Kemp, Katja Fischer, and Anna M. Blom
J Immunol 2009 182: 7809-7817; doi:10.4049/jimmunol.0804205 [Abstract] [Full Text] [PDF]  

SP-A Preserves Airway Homeostasis During Mycoplasma pneumoniae Infection in Mice

Julie G. Ledford, Hisatsugu Goto, Erin N. Potts, Simone Degan, Hong Wei Chu, Dennis R. Voelker, Mary E. Sunday, George J. Cianciolo, William M. Foster, Monica Kraft, and Jo Rae Wright
J Immunol 2009 182: 7818-7827; doi:10.4049/jimmunol.0900452 [Abstract] [Full Text] [PDF]  

Heterogeneity in HIV Suppression by CD8 T Cells from HIV Controllers: Association with Gag-Specific CD8 T Cell Responses

Asier Sáez-Cirión, Martine Sinet, So Youn Shin, Alejandra Urrutia, Pierre Versmisse, Christine Lacabaratz, Faroudy Boufassa, Véronique Avettand-Fènoël, Christine Rouzioux, Jean-François Delfraissy, Françoise Barré-Sinoussi, Olivier Lambotte, Alain Venet, Gianfranco Pancino for the ANRS EP36 HIV Controllers Study Group
J Immunol 2009 182: 7828-7837; doi:10.4049/jimmunol.0803928 [Abstract] [Full Text] [PDF]  

Culling of Activated CD4 T Cells during Typhoid Is Driven by Salmonella Virulence Genes

Aparna Srinivasan, Minelva Nanton, Amanda Griffin, and Stephen J. McSorley
J Immunol 2009 182: 7838-7845; doi:10.4049/jimmunol.0900382 [Abstract] [Full Text] [PDF]  

IL-17 Receptor Signaling Is Required to Control Polymicrobial Sepsis

Andressa Freitas, José C. Alves-Filho, Tatiana Victoni, Thomas Secher, Henrique P. Lemos, Fabiane Sônego, Fernando Q. Cunha, and Bernhard Ryffel
J Immunol 2009 182: 7846-7854; doi:10.4049/jimmunol.0803039 [Abstract] [Full Text] [PDF]  

Crucial Role of TNF Receptors 1 and 2 in the Control of Polymicrobial Sepsis

Thomas Secher, Virginie Vasseur, Didier Marc Poisson, Jane A. Mitchell, Fernando Q. Cunha, José Carlos Alves-Filho, and Bernhard Ryffel
J Immunol 2009 182: 7855-7864; doi:10.4049/jimmunol.0804008 [Abstract] [Full Text] [PDF]  

Clinical Isolates of Streptococcus pneumoniae Bind the Complement Inhibitor C4b-Binding Protein in a PspC Allele-Dependent Fashion

Antoine Dieudonné-Vatran, Stefanie Krentz, Anna M. Blom, Seppo Meri, Birgitta Henriques-Normark, Kristian Riesbeck, and Barbara Albiger
J Immunol 2009 182: 7865-7877; doi:10.4049/jimmunol.0802376 [Abstract] [Full Text] [PDF]  

Interactions of -, β-, and -Defensins with Influenza A Virus and Surfactant Protein D

Mona Doss, Mitchell R. White, Tesfaldet Tecle, Donald Gantz, Erika C. Crouch, Grace Jung, Piotr Ruchala, Alan J. Waring, Robert I. Lehrer, and Kevan L. Hartshorn
J Immunol 2009 182: 7878-7887; doi:10.4049/jimmunol.0804049 [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Social Stress Enhances Allergen-Induced Airway Inflammation in Mice and Inhibits Corticosteroid Responsiveness of Cytokine Production

Michael T. Bailey, Sonja Kierstein, Satish Sharma, Matthew Spaits, Steven G. Kinsey, Omar Tliba, John F. Sheridan, Reynold A. Panettieri, and Angela Haczku
J Immunol 2009 182: 7888-7896; doi:10.4049/jimmunol.0800891 [Abstract] [Full Text] [PDF]  

Steel Factor Enhances Supraoptimal Antigen-Induced IL-6 Production from Mast Cells via Activation of Protein Kinase C-β

Kerstin Fehrenbach, Eva Lessmann, Carolin N. Zorn, Marcel Kuhny, Gordon Grochowy, Gerald Krystal, Michael Leitges, and Michael Huber
J Immunol 2009 182: 7897-7905; doi:10.4049/jimmunol.0801773 [Abstract] [Full Text] [PDF]  

Neutrophil-Derived Proteinase 3 Induces Kallikrein-Independent Release of a Novel Vasoactive Kinin

Robin Kahn, Thomas Hellmark, L. M. Fredrik Leeb-Lundberg, Nasrin Akbari, Mihail Todiras, Tor Olofsson, Jörgen Wieslander, Anders Christensson, Kerstin Westman, Michael Bader, Werner Müller-Esterl, and Diana Karpman
J Immunol 2009 182: 7906-7915; doi:10.4049/jimmunol.0803624 [Abstract] [Full Text] [PDF]  

Thrombin-Induced Connective Tissue Growth Factor Expression in Human Lung Fibroblasts Requires the ASK1/JNK/AP-1 Pathway

Chung-Chi Yu, Ming-Jen Hsu, Min-Liang Kuo, Robert Fu-Chean Chen, Mei-Chieh Chen, Kua-Jen Bai, Ming-Chih Yu, Bing-Chang Chen, and Chien-Huang Lin
J Immunol 2009 182: 7916-7927; doi:10.4049/jimmunol.0801582 [Abstract] [Full Text] [PDF]  

Atherogenic Lipids Induce High-Density Lipoprotein Uptake and Cholesterol Efflux in Human Macrophages by Up-Regulating Transmembrane Chemokine CXCL16 without Engaging CXCL16-Dependent Cell Adhesion

Jana Barlic, Wenjia Zhu, and Philip M. Murphy
J Immunol 2009 182: 7928-7936; doi:10.4049/jimmunol.0804112 [Abstract] [Full Text] [PDF] Data Supplement  

Increase in ALK1/ALK5 Ratio as a Cause for Elevated MMP-13 Expression in Osteoarthritis in Humans and Mice

Esmeralda N. Blaney Davidson, Dennis F. G. Remst, Elly L. Vitters, Henk M. van Beuningen, Arjen B. Blom, Marie-Jose Goumans, Wim B. van den Berg, and Peter M. van der Kraan
J Immunol 2009 182: 7937-7945; doi:10.4049/jimmunol.0803991 [Abstract] [Full Text] [PDF]  

Endotoxin Augmented Antigen-Induced Th1 Cell Trafficking Amplifies Airway Neutrophilic Inflammation

Zamaneh Mikhak, Alireza Farsidjani, and Andrew D. Luster
J Immunol 2009 182: 7946-7956; doi:10.4049/jimmunol.0803522 [Abstract] [Full Text] [PDF] Data Supplement  

Glutamine Protects Mice from Lethal Endotoxic Shock via a Rapid Induction of MAPK Phosphatase-1

Hyun-Mi Ko, Sin-Hye Oh, Hwa-Suk Bang, Nam-In Kang, Baik-Hwan Cho, Suhn-Young Im, and Hern-Ku Lee
J Immunol 2009 182: 7957-7962; doi:10.4049/jimmunol.0900043 [Abstract] [Full Text] [PDF]  

Cytokine Modulation of TLR Expression and Activation in Mesenchymal Stromal Cells Leads to a Proinflammatory Phenotype

Raphaëlle Romieu-Mourez, Moïra François, Marie-Noëlle Boivin, Manaf Bouchentouf, David E. Spaner, and Jacques Galipeau
J Immunol 2009 182: 7963-7973; doi:10.4049/jimmunol.0803864 [Abstract] [Full Text] [PDF] Data Supplement  

Hypoxia Prolongs Monocyte/Macrophage Survival and Enhanced Glycolysis Is Associated with Their Maturation under Aerobic Conditions

John Roiniotis, Hang Dinh, Paul Masendycz, Amanda Turner, Caryn L. Elsegood, Glen M. Scholz, and John A. Hamilton
J Immunol 2009 182: 7974-7981; doi:10.4049/jimmunol.0804216 [Abstract] [Full Text] [PDF]  

Pyrin Critical to Macrophage IL-1β Response to Francisella Challenge

Mikhail A. Gavrilin, Srabani Mitra, Sudarshan Seshadri, Jyotsna Nateri, Freweine Berhe, Mark W. Hall, and Mark D. Wewers
J Immunol 2009 182: 7982-7989; doi:10.4049/jimmunol.0803073 [Abstract] [Full Text] [PDF] Data Supplement  

Myeloperoxidase Deficiency Attenuates Lipopolysaccharide-Induced Acute Lung Inflammation and Subsequent Cytokine and Chemokine Production

Astrid Haegens, Peter Heeringa, Robert Jan van Suylen, Chad Steele, Yasuaki Aratani, Robert J. J. O'Donoghue, Steven E. Mutsaers, Brooke T. Mossman, Emiel F. M. Wouters, and Juanita H. J. Vernooy
J Immunol 2009 182: 7990-7996; doi:10.4049/jimmunol.0800377 [Abstract] [Full Text] [PDF]  

Lipopolysaccharide Stimulates Platelet Secretion and Potentiates Platelet Aggregation via TLR4/MyD88 and the cGMP-Dependent Protein Kinase Pathway

Guoying Zhang, Jingyan Han, Emily J. Welch, Richard D. Ye, Tatyana A. Voyno-Yasenetskaya, Asrar B. Malik, Xiaoping Du, and Zhenyu Li
J Immunol 2009 182: 7997-8004; doi:10.4049/jimmunol.0802884 [Abstract] [Full Text] [PDF] Data Supplement  

Metformin Attenuated the Autoimmune Disease of the Central Nervous System in Animal Models of Multiple Sclerosis

Narender Nath, Musfiquidin Khan, Manjeet K. Paintlia, Md Nasrul Hoda, and Shailendra Giri
J Immunol 2009 182: 8005-8014; doi:10.4049/jimmunol.0803563 [Abstract] [Full Text] [PDF]  

₉ Integrin and Its Ligands Constitute Critical Joint Microenvironments for Development of Autoimmune Arthritis

Masashi Kanayama, Daisuke Kurotaki, Junko Morimoto, Tsuyoshi Asano, Yutaka Matsui, Yosuke Nakayama, Yoshinari Saito, Koyu Ito, Chiemi Kimura, Norimasa Iwasaki, Koji Suzuki, Tanenobu Harada, Hong Mei Li, Jun Uehara, Tadaaki Miyazaki, Akio Minami, Shigeyuki Kon, and Toshimitsu Uede
J Immunol 2009 182: 8015-8025; doi:10.4049/jimmunol.0900725 [Abstract] [Full Text] [PDF] Data Supplement  

Association of FcRIIa (CD32a) with Lipid Rafts Regulates Ligand Binding Activity

Stylianos Bournazos, Simon P. Hart, Luke H. Chamberlain, Martin J. Glennie, and Ian Dransfield
J Immunol 2009 182: 8026-8036; doi:10.4049/jimmunol.0900107 [Abstract] [Full Text] [PDF]  

Enhanced Airway Inflammation and Remodeling in Adenosine Deaminase-Deficient Mice Lacking the A_2B Adenosine Receptor

Yang Zhou, Amir Mohsenin, Eva Morschl, Hays W. J. Young, Jose G. Molina, Wenbin Ma, Chun-Xiao Sun, Hector Martinez-Valdez, and Michael R. Blackburn
J Immunol 2009 182: 8037-8046; doi:10.4049/jimmunol.0900515 [Abstract] [Full Text] [PDF]  

Tuberculosis Subunit Vaccination Provides Long-Term Protective Immunity Characterized by Multifunctional CD4 Memory T Cells

Thomas Lindenstrøm, Else Marie Agger, Karen S. Korsholm, Patricia A. Darrah, Claus Aagaard, Robert A. Seder, Ida Rosenkrands, and Peter Andersen
J Immunol 2009 182: 8047-8055; doi:10.4049/jimmunol.0801592 [Abstract] [Full Text] [PDF] Data Supplement  

Neutrophil-Derived IL-6 Limits Alveolar Barrier Disruption in Experimental Ventilator-Induced Lung Injury

Paul J. Wolters, Charlie Wray, Rachel E. Sutherland, Sophia S. Kim, Jon Koff, Ying Mao, and James A. Frank
J Immunol 2009 182: 8056-8062; doi:10.4049/jimmunol.0801323 [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Chlamydia trachomatis Native Major Outer Membrane Protein Induces Partial Protection in Nonhuman Primates: Implication for a Trachoma Transmission-Blocking Vaccine

Laszlo Kari, William M. Whitmire, Deborah D. Crane, Nathalie Reveneau, John H. Carlson, Morgan M. Goheen, Ellena M. Peterson, Sukumar Pal, Luis M. de la Maza, and Harlan D. Caldwell
J Immunol 2009 182: 8063-8070; doi:10.4049/jimmunol.0804375 [Abstract] [Full Text] [PDF]  

Defective Regulatory T Cells In Patients with Severe Drug Eruptions: Timing of the Dysfunction Is Associated with the Pathological Phenotype and Outcome

Ryo Takahashi, Yoko Kano, Yoshimi Yamazaki, Momoko Kimishima, Yoshiko Mizukawa, and Tetsuo Shiohara
J Immunol 2009 182: 8071-8079; doi:10.4049/jimmunol.0804002 [Abstract] [Full Text] [PDF]  

Cross-Presentation of Male Seminal Fluid Antigens Elicits T Cell Activation to Initiate the Female Immune Response to Pregnancy

Lachlan M. Moldenhauer, Kerrilyn R. Diener, Dougal M. Thring, Michael P. Brown, John D. Hayball, and Sarah A. Robertson
J Immunol 2009 182: 8080-8093; doi:10.4049/jimmunol.0804018 [Abstract] [Full Text] [PDF]  

Selective Up-Regulation of Intact, but Not Defective env RNAs of Endogenous Modified Polytropic Retrovirus by the Sgp3 Locus of Lupus-Prone Mice

Kumiko Yoshinobu, Lucie Baudino, Marie-Laure Santiago-Raber, Naoki Morito, Isabelle Dunand-Sauthier, Bernard J. Morley, Leonard H. Evans, and Shozo Izui
J Immunol 2009 182: 8094-8103; doi:10.4049/jimmunol.0900263 [Abstract] [Full Text] [PDF]  

Selective Autoantibody Production against CCL3 Is Associated with Human Type 1 Diabetes Mellitus and Serves As a Novel Biomarker for Its Diagnosis

Naim Shehadeh, Shirly Pollack, Gizi Wildbaum, Yaniv Zohar, Itay Shafat, Reem Makhoul, Essam Daod, Fahed Hakim, Rina Perlman, and Nathan Karin
J Immunol 2009 182: 8104-8109; doi:10.4049/jimmunol.0803348 [Abstract] [Full Text] [PDF]  

Suppression of IgE B Cells and IgE Binding to FcRI by Gene Therapy with Single-Chain Anti-IgE

Takayuki Ota, Miyo Aoki-Ota, Bao Hoa Duong, and David Nemazee
J Immunol 2009 182: 8110-8117; doi:10.4049/jimmunol.0900300 [Abstract] [Full Text] [PDF] Data Supplement  

Reduced Expression of the Mevalonate Pathway Enzyme Farnesyl Pyrophosphate Synthase Unveils Recognition of Tumor Cells by V9V2 T Cells

Jianqiang Li, Marco J. Herold, Brigitte Kimmel, Ingrid Müller, Bladimiro Rincon-Orozco, Volker Kunzmann, and Thomas Herrmann
J Immunol 2009 182: 8118-8124; doi:10.4049/jimmunol.0900101 [Abstract] [Full Text] [PDF]  

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