IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2009 182: 5887-5888; doi:10.4049/jimmunol.0990035 [Full Text] [PDF] ImmunoCast  

LETTERS TO THE EDITOR:

Comment on "Hepatitis C Virus-Specific Th17 Cells Are Suppressed by Virus-Induced TGF-β"

Krzysztof Gutkowski and Marek Hartleb
J Immunol 2009 182: 5889; doi:10.4049/jimmunol.0990036 [Full Text] [PDF]  

Response to Comment on "Hepatitis C Virus-Specific Th17 Cells Are Suppressed by Virus-Induced TGF-β"

Kingston H. G. Mills, Aileen G. Rowan, and Jean M. Fletcher
J Immunol 2009 182: 5889-5890; doi:10.4049/jimmunol.0990037 [Full Text] [PDF]  

BRIEF REVIEWS:

PD-1 and CTLA-4 Inhibitory Cosignaling Pathways in HIV Infection and the Potential for Therapeutic Intervention

Daniel E. Kaufmann and Bruce D. Walker
J Immunol 2009 182: 5891-5897; doi:10.4049/jimmunol.0803771 [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: Negative Regulation of Dendritic Cells through Acetylation of the Nonhistone Protein STAT-3

Yaping Sun, Y. Eugene Chin, Elizabeth Weisiger, Chelsea Malter, Isao Tawara, Tomomi Toubai, Erin Gatza, Paolo Mascagni, Charles A. Dinarello, and Pavan Reddy
J Immunol 2009 182: 5899-5903; doi:10.4049/jimmunol.0804388 [Abstract] [Full Text] [PDF] Data Supplement  

Cutting Edge: IL-23 Receptor GFP Reporter Mice Reveal Distinct Populations of IL-17-Producing Cells

Amit Awasthi, Lorena Riol-Blanco, Anneli Jäger, Thomas Korn, Caroline Pot, George Galileos, Estelle Bettelli, Vijay K. Kuchroo, and Mohamed Oukka
J Immunol 2009 182: 5904-5908; doi:10.4049/jimmunol.0900732 [Abstract] [Full Text] [PDF]  

Cutting Edge: Natalizumab Blocks Adhesion but Not Initial Contact of Human T Cells to the Blood-Brain Barrier In Vivo in an Animal Model of Multiple Sclerosis

Caroline Coisne, Wenxian Mao, and Britta Engelhardt
J Immunol 2009 182: 5909-5913; doi:10.4049/jimmunol.0803418 [Abstract] [Full Text] [PDF] Data Supplement  

Cutting Edge: Unusual NK Cell Responses to HIV-1 Peptides Are Associated with Protection against Maternal-Infant Transmission of HIV-1

Caroline T. Tiemessen, Sharon Shalekoff, Stephen Meddows-Taylor, Diana B. Schramm, Maria A. Papathanasopoulos, Glenda E. Gray, Gayle G. Sherman, Ashraf H. Coovadia, and Louise Kuhn
J Immunol 2009 182: 5914-5918; doi:10.4049/jimmunol.0900419 [Abstract] [Full Text] [PDF] Data Supplement  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Naive CD4 T Cell Proliferation Is Controlled by Mammalian Target of Rapamycin Regulation of GRAIL Expression

Jack T. Lin, Neil B. Lineberry, Michael G. Kattah, Leon L. Su, Paul J. Utz, C. Garrison Fathman, and Linda Wu
J Immunol 2009 182: 5919-5928; doi:10.4049/jimmunol.0803986 [Abstract] [Full Text] [PDF] Data Supplement  

A Major Lipid Raft Protein Raftlin Modulates T Cell Receptor Signaling and Enhances Th17-Mediated Autoimmune Responses

Kazuko Saeki, Satoru Fukuyama, Toranoshin Ayada, Mako Nakaya, Daisuke Aki, Giichi Takaesu, Toshikatsu Hanada, Yumiko Matsumura, Takashi Kobayashi, Ryusuke Nakagawa, and Akihiko Yoshimura
J Immunol 2009 182: 5929-5937; doi:10.4049/jimmunol.0802672 [Abstract] [Full Text] [PDF] Data Supplement  

Central Memory CD8⁺ T Cells Induce Graft-versus-Host Disease and Mediate Graft-versus-Leukemia

Hong Zheng, Catherine Matte-Martone, Dhanpat Jain, Jennifer McNiff, and Warren D. Shlomchik
J Immunol 2009 182: 5938-5948; doi:10.4049/jimmunol.0802212 [Abstract] [Full Text] [PDF] Data Supplement  

CD8 T Cells Producing IL-17 and IFN- Initiate the Innate Immune Response Required for Responses to Antigen Skin Challenge

Danielle D. Kish, Xiaoxia Li, and Robert L. Fairchild
J Immunol 2009 182: 5949-5959; doi:10.4049/jimmunol.0802830 [Abstract] [Full Text] [PDF]  

Lentivector Immunization Stimulates Potent CD8 T Cell Responses against Melanoma Self-Antigen Tyrosinase-Related Protein 1 and Generates Antitumor Immunity in Mice

Yanjun Liu, Yibing Peng, Michael Mi, Jose Guevara-Patino, David H. Munn, Ning Fu, and Yukai He
J Immunol 2009 182: 5960-5969; doi:10.4049/jimmunol.0900008 [Abstract] [Full Text] [PDF]  

Free Bone Graft Attenuates Acute Rejection and in Combination with Cyclosporin A Leads to Indefinite Cardiac Allograft Survival

Hao Wang, Wei Ge, Jacqueline Arp, Roman Zassoko, Weihua Liu, Thomas E. Ichim, Jifu Jiang, Anthony M. Jevnikar, and Bertha Garcia
J Immunol 2009 182: 5970-5981; doi:10.4049/jimmunol.0801037 [Abstract] [Full Text] [PDF]  

Novel Human Transitional B Cell Populations Revealed by B Cell Depletion Therapy

Arumugam Palanichamy, Jennifer Barnard, Bo Zheng, Teresa Owen, Tam Quach, Chungwen Wei, R. John Looney, Iñaki Sanz, and Jennifer H. Anolik
J Immunol 2009 182: 5982-5993; doi:10.4049/jimmunol.0801859 [Abstract] [Full Text] [PDF]  

Mesenchymal Stromal Cells Ameliorate Experimental Autoimmune Encephalomyelitis by Inhibiting CD4 Th17 T Cells in a CC Chemokine Ligand 2-Dependent Manner

Moutih Rafei, Philippe M. Campeau, Adriana Aguilar-Mahecha, Marguerite Buchanan, Patrick Williams, Elena Birman, Shala Yuan, Yoon Kow Young, Marie-Noëlle Boivin, Kathy Forner, Mark Basik, and Jacques Galipeau
J Immunol 2009 182: 5994-6002; doi:10.4049/jimmunol.0803962 [Abstract] [Full Text] [PDF] Data Supplement  

Involvement of Glycoreceptors in Galactoxylomannan-Induced T Cell Death

Eva Pericolini, Elena Gabrielli, Elio Cenci, Magdia De Jesus, Francesco Bistoni, Arturo Casadevall, and Anna Vecchiarelli
J Immunol 2009 182: 6003-6010; doi:10.4049/jimmunol.0803833 [Abstract] [Full Text] [PDF]  

A Network Modeling Approach to Analysis of the Th2 Memory Responses Underlying Human Atopic Disease

Anthony Bosco, Kathy L. McKenna, Martin J. Firth, Peter D. Sly, and Patrick G. Holt
J Immunol 2009 182: 6011-6021; doi:10.4049/jimmunol.0804125 [Abstract] [Full Text] [PDF] Data Supplement  

Protein Kinase C Focusing at the cSMAC Is a Consequence rather than Cause of TCR Signaling and Is Dependent on the MEK/ERK Pathway

Kesavannair Praveen, Yan Zheng, Fabiola Rivas, and Thomas F. Gajewski
J Immunol 2009 182: 6022-6030; doi:10.4049/jimmunol.0800897 [Abstract] [Full Text] [PDF]  

IgM Antibodies to Apoptosis-Associated Determinants Recruit C1q and Enhance Dendritic Cell Phagocytosis of Apoptotic Cells

Yifang Chen, Yong-Beom Park, Ekta Patel, and Gregg J. Silverman
J Immunol 2009 182: 6031-6043; doi:10.4049/jimmunol.0804191 [Abstract] [Full Text] [PDF]  

Activation of Melanoma Differentiation-Associated Gene 5 Causes Rapid Involution of the Thymus

David Anz, Raffael Thaler, Nicolas Stephan, Zoe Waibler, Michael J. Trauscheid, Christoph Scholz, Ulrich Kalinke, Winfried Barchet, Stefan Endres, and Carole Bourquin
J Immunol 2009 182: 6044-6050; doi:10.4049/jimmunol.0803809 [Abstract] [Full Text] [PDF]  

Adeno-Associated Virus Capsid Structure Drives CD4-Dependent CD8⁺ T Cell Response to Vector Encoded Proteins

Lauren E. Mays, Luk H. Vandenberghe, Ru Xiao, Peter Bell, Hyun-Joo Nam, Mavis Agbandje-McKenna, and James M. Wilson
J Immunol 2009 182: 6051-6060; doi:10.4049/jimmunol.0803965 [Abstract] [Full Text] [PDF]  

Targeted Delivery of Immunogen to Primate M Cells with Tetragalloyl Lysine Dendrimer

Shogo Misumi, Mitsuaki Masuyama, Nobutoki Takamune, Daisuke Nakayama, Ryotarou Mitsumata, Hirokazu Matsumoto, Norimitsu Urata, Yoshihiro Takahashi, Atsunobu Muneoka, Takayuki Sukamoto, Koichiro Fukuzaki, and Shozo Shoji
J Immunol 2009 182: 6061-6070; doi:10.4049/jimmunol.0802928 [Abstract] [Full Text] [PDF]  

Expansion of Antigen-Specific Regulatory T Cells with the Topical Vitamin D Analog Calcipotriol

Mehran Ghoreishi, Paxton Bach, Jennifer Obst, Mitsuhiro Komba, James C. Fleet, and Jan P. Dutz
J Immunol 2009 182: 6071-6078; doi:10.4049/jimmunol.0804064 [Abstract] [Full Text] [PDF]  

RANK-RANKL Signaling Pathway Is Critically Involved in the Function of CD4⁺CD25⁺ Regulatory T Cells in Chronic Colitis

Teruji Totsuka, Takanori Kanai, Yasuhiro Nemoto, Takayuki Tomita, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Naoya Sakamoto, Hisaya Akiba, Ko Okumura, Hideo Yagita, and Mamoru Watanabe
J Immunol 2009 182: 6079-6087; doi:10.4049/jimmunol.0711823 [Abstract] [Full Text] [PDF]  

IL-31-IL-31R Interactions Limit the Magnitude of Th2 Cytokine-Dependent Immunity and Inflammation following Intestinal Helminth Infection

Jacqueline G. Perrigoue, Colby Zaph, Katherine Guild, Yurong Du, and David Artis
J Immunol 2009 182: 6088-6094; doi:10.4049/jimmunol.0802459 [Abstract] [Full Text] [PDF]  

Effector/Memory but Not Naive Regulatory T Cells Are Responsible for the Loss of Concomitant Tumor Immunity

Yung-Chang Lin, Li-Yuan Chang, Ching-Tai Huang, Hui-Min Peng, Avijit Dutta, Tse-Ching Chen, Chau-Ting Yeh, and Chun-Yen Lin
J Immunol 2009 182: 6095-6104; doi:10.4049/jimmunol.0803829 [Abstract] [Full Text] [PDF]  

Role of Marginal Zone B Lymphocytes in Invariant NKT Cell Activation

Emilie Bialecki, Christophe Paget, Josette Fontaine, Monique Capron, François Trottein, and Christelle Faveeuw
J Immunol 2009 182: 6105-6113; doi:10.4049/jimmunol.0802273 [Abstract] [Full Text] [PDF]  

Presence of Membrane-Bound TGF-β1 and Its Regulation by IL-2-Activated Immune Cell-Derived IFN- in Head and Neck Squamous Cell Carcinoma Cell Lines

Yong-Oon Ahn, June-Chul Lee, Myung-Whun Sung, and Dae Seog Heo
J Immunol 2009 182: 6114-6120; doi:10.4049/jimmunol.0803725 [Abstract] [Full Text] [PDF]  

Regulatory T Cell Suppression Is Potentiated by Target T Cells in a Cell Contact, IL-35- and IL-10-Dependent Manner

Lauren W. Collison, Meenu R. Pillai, Vandana Chaturvedi, and Dario A. A. Vignali
J Immunol 2009 182: 6121-6128; doi:10.4049/jimmunol.0803646 [Abstract] [Full Text] [PDF] Data Supplement  

Proinflammatory Adjuvants Enhance the Cognate Helper Activity of Aged CD4 T Cells

Alexander C. Maue, Sheri M. Eaton, Paula A. Lanthier, Kathryn B. Sweet, Seth L. Blumerman, and Laura Haynes
J Immunol 2009 182: 6129-6135; doi:10.4049/jimmunol.0804226 [Abstract] [Full Text] [PDF]  

Impaired Mast Cell-Driven Immune Responses in Mice Lacking the Transcription Factor NFATc2

Marc Becker, Valeska Heib, Matthias Klein, Fatma Doener, Tobias Bopp, Christian Taube, Markus Radsak, Hansjörg Schild, Edgar Schmitt, and Michael Stassen
J Immunol 2009 182: 6136-6142; doi:10.4049/jimmunol.0802878 [Abstract] [Full Text] [PDF]  

Autoreactive Anti-DNA Transgenic B Cells in Lupus-Prone New Zealand Black/New Zealand White Mice Show Near Perfect L Chain Allelic Exclusion

Efi Makdasi, Ruth Fischel, Inbal Kat, and Dan Eilat
J Immunol 2009 182: 6143-6148; doi:10.4049/jimmunol.0803610 [Abstract] [Full Text] [PDF] Data Supplement  

Hepatocytes and IL-15: A Favorable Microenvironment for T Cell Survival and CD8⁺ T Cell Differentiation

Margareta P. Correia, Elsa M. Cardoso, Carlos F. Pereira, Rui Neves, Markus Uhrberg, and Fernando A. Arosa
J Immunol 2009 182: 6149-6159; doi:10.4049/jimmunol.0802470 [Abstract] [Full Text] [PDF]  

Tumor Regulatory T Cells Potently Abrogate Antitumor Immunity

Zuqiang Liu, Jin H. Kim, Louis D. Falo, Jr., and Zhaoyang You
J Immunol 2009 182: 6160-6167; doi:10.4049/jimmunol.0802664 [Abstract] [Full Text] [PDF]  

Notch Activation Induces the Generation of Functional NK Cells from Human Cord Blood CD34-Positive Cells Devoid of IL-15

Kyoko Haraguchi, Takahiro Suzuki, Noriko Koyama, Keiki Kumano, Fumio Nakahara, Akihiko Matsumoto, Yasuhisa Yokoyama, Mamiko Sakata-Yanagimoto, Shigeo Masuda, Tsuyoshi Takahashi, Aki Kamijo, Koki Takahashi, Minoko Takanashi, Yoshiki Okuyama, Koji Yasutomo, Seiji Sakano, Hideo Yagita, Mineo Kurokawa, Seishi Ogawa, and Shigeru Chiba
J Immunol 2009 182: 6168-6178; doi:10.4049/jimmunol.0803036 [Abstract] [Full Text] [PDF] Data Supplement  

T-bet Inhibits the In Vivo Differentiation of Parasite-Specific CD4⁺ Th17 Cells in a T Cell-Intrinsic Manner

Siqi Guo, Dustin Cobb, and Ronald B. Smeltz
J Immunol 2009 182: 6179-6186; doi:10.4049/jimmunol.0803821 [Abstract] [Full Text] [PDF]  

Hematopoietic Progenitor Kinase 1 Is a Negative Regulator of Dendritic Cell Activation

Saba Alzabin, Nina Bhardwaj, Friedemann Kiefer, Sansana Sawasdikosol, and Steven Burakoff
J Immunol 2009 182: 6187-6194; doi:10.4049/jimmunol.0802631 [Abstract] [Full Text] [PDF] Data Supplement  

Differentiation of Central Memory CD8 T Cells Is Independent of CD62L-Mediated Trafficking to Lymph Nodes

Thomas C. Wirth, Vladimir P. Badovinac, Lichao Zhao, Morris O. Dailey, and John T. Harty
J Immunol 2009 182: 6195-6206; doi:10.4049/jimmunol.0803315 [Abstract] [Full Text] [PDF]  

Tumor-Educated CD11b^highIa^low Regulatory Dendritic Cells Suppress T Cell Response through Arginase I

Qiuyan Liu, Chaoxiong Zhang, Anna Sun, Yuanyuan Zheng, Li Wang, and Xuetao Cao
J Immunol 2009 182: 6207-6216; doi:10.4049/jimmunol.0803926 [Abstract] [Full Text] [PDF] Data Supplement  

TLR Signals Promote IL-6/IL-17-Dependent Transplant Rejection

Luqiu Chen, Emily Ahmed, Tongmin Wang, Ying Wang, Jordi Ochando, Anita S. Chong, and Maria-Luisa Alegre
J Immunol 2009 182: 6217-6225; doi:10.4049/jimmunol.0803842 [Abstract] [Full Text] [PDF]  

c-Maf Regulates IL-10 Expression during Th17 Polarization

Jiangnan Xu, Yu Yang, Guixing Qiu, Girdhari Lal, Zhihong Wu, David E. Levy, Jordi C. Ochando, Jonathan S. Bromberg, and Yaozhong Ding
J Immunol 2009 182: 6226-6236; doi:10.4049/jimmunol.0900123 [Abstract] [Full Text] [PDF]  

M1 and M2a Polarization of Human Monocyte-Derived Macrophages Inhibits HIV-1 Replication by Distinct Mechanisms

Edana Cassol, Luca Cassetta, Chiara Rizzi, Massimo Alfano, and Guido Poli
J Immunol 2009 182: 6237-6246; doi:10.4049/jimmunol.0803447 [Abstract] [Full Text] [PDF]  

Withdrawal of Sex Steroids Reverses Age- and Chemotherapy-Related Defects in Bone Marrow Lymphopoiesis

Jarrod A. Dudakov, Gabrielle L. Goldberg, Jessica J. Reiseger, Ann P. Chidgey, and Richard L. Boyd
J Immunol 2009 182: 6247-6260; doi:10.4049/jimmunol.0802446 [Abstract] [Full Text] [PDF]  

Follicular and Marginal Zone B Cells Fail to Cross-Present MHC Class I-Restricted Epitopes Derived from Viral Particles

Susanne A. Keller, Caroline E. von Allmen, Heather J. Hinton, Monika Bauer, Simone Muntwiler, Klaus Dietmeier, Philippe Saudan, and Martin F. Bachmann
J Immunol 2009 182: 6261-6266; doi:10.4049/jimmunol.0804035 [Abstract] [Full Text] [PDF]  

A Programmed Switch from IL-15- to IL-2-Dependent Activation in Human NK Cells

Anne-Hélène Pillet, Florence Bugault, Jacques Thèze, Lisa A. Chakrabarti, and Thierry Rose
J Immunol 2009 182: 6267-6277; doi:10.4049/jimmunol.0801933 [Abstract] [Full Text] [PDF]  

The Adaptor Molecule MyD88 Directly Promotes CD8 T Cell Responses to Vaccinia Virus

Yuan Zhao, Carl De Trez, Rachel Flynn, Carl F. Ware, Michael Croft, and Shahram Salek-Ardakani
J Immunol 2009 182: 6278-6286; doi:10.4049/jimmunol.0803682 [Abstract] [Full Text] [PDF]  

Differential Expression of Granzyme B and C in Murine Cytotoxic Lymphocytes

Sheng F. Cai, Todd A. Fehniger, Xuefang Cao, Joshua C. Mayer, Joel D. Brune, Anthony R. French, and Timothy J. Ley
J Immunol 2009 182: 6287-6297; doi:10.4049/jimmunol.0804333 [Abstract] [Full Text] [PDF] Data Supplement  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

A Combination Vaccine for Allergy and Rhinovirus Infections Based on Rhinovirus-Derived Surface Protein VP1 and a Nonallergenic Peptide of the Major Timothy Grass Pollen Allergen Phl p 1

Johanna Edlmayr, Katarzyna Niespodziana, Birgit Linhart, Margarete Focke-Tejkl, Kerstin Westritschnig, Sandra Scheiblhofer, Angelika Stoecklinger, Michael Kneidinger, Peter Valent, Raffaela Campana, Josef Thalhamer, Theresia Popow-Kraupp, and Rudolf Valenta
J Immunol 2009 182: 6298-6306; doi:10.4049/jimmunol.0713622 [Abstract] [Full Text] [PDF] Data Supplement  

Histone Deacetylases Inhibit IFN--Inducible Gene Expression in Mouse Trophoblast Cells

Jason C. Choi, Renae Holtz, and Shawn P. Murphy
J Immunol 2009 182: 6307-6315; doi:10.4049/jimmunol.0802454 [Abstract] [Full Text] [PDF]  

Protein Kinase D1 Is Essential for MyD88-Dependent TLR Signaling Pathway

Jeoung-Eun Park, Young-In Kim, and Ae-Kyung Yi
J Immunol 2009 182: 6316-6327; doi:10.4049/jimmunol.0804239 [Abstract] [Full Text] [PDF]  

Expression Hierarchy of T Cell Epitopes from Melanoma Differentiation Antigens: Unexpected High Level Presentation of Tyrosinase-HLA-A2 Complexes Revealed by Peptide-Specific, MHC-Restricted, TCR-Like Antibodies

Yael Michaeli, Galit Denkberg, Keren Sinik, Liz Lantzy, Chiang Chih-Sheng, Celine Beauverd, Tamar Ziv, Pedro Romero, and Yoram Reiter
J Immunol 2009 182: 6328-6341; doi:10.4049/jimmunol.0801898 [Abstract] [Full Text] [PDF] Data Supplement  

In Vivo Enhancement of Peptide Display by MHC Class II Molecules with Small Molecule Catalysts of Peptide Exchange

Melissa J. Call, Xuechao Xing, Gregory D. Cuny, Nilufer P. Seth, Daniel M. Altmann, Lars Fugger, Michelle Krogsgaard, Ross L. Stein, and Kai W. Wucherpfennig
J Immunol 2009 182: 6342-6352; doi:10.4049/jimmunol.0803464 [Abstract] [Full Text] [PDF] Data Supplement  

A Backup Role of DNA Polymerase in Ig Gene Hypermutation Only Takes Place in the Complete Absence of DNA Polymerase

Ahmad Faili, Anne Stary, Frédéric Delbos, Sandra Weller, Said Aoufouchi, Alain Sarasin, Jean-Claude Weill, and Claude-Agnès Reynaud
J Immunol 2009 182: 6353-6359; doi:10.4049/jimmunol.0900177 [Abstract] [Full Text] [PDF] Data Supplement  

HOST DEFENSE:

Critical Roles of NK and CD8⁺ T Cells in Central Nervous System Listeriosis

Toshiyuki Hayashi, Shigenori Nagai, Hideki Fujii, Yukiko Baba, Eiji Ikeda, Takeshi Kawase, and Shigeo Koyasu
J Immunol 2009 182: 6360-6368; doi:10.4049/jimmunol.0803798 [Abstract] [Full Text] [PDF]  

Proximal Glycans Outside of the Epitopes Regulate the Presentation of HIV-1 Envelope gp120 Helper Epitopes

Hualin Li, Chong-Feng Xu, Steven Blais, Qi Wan, Hui-Tang Zhang, Samuel J. Landry, and Catarina E. Hioe
J Immunol 2009 182: 6369-6378; doi:10.4049/jimmunol.0804287 [Abstract] [Full Text] [PDF] Data Supplement  

Dynamic Imaging of T Cell-Parasite Interactions in the Brains of Mice Chronically Infected with Toxoplasma gondii

Marie Schaeffer, Seong-Ji Han, Tatyana Chtanova, Giel G. van Dooren, Paul Herzmark, Ying Chen, Badrinath Roysam, Boris Striepen, and Ellen A. Robey
J Immunol 2009 182: 6379-6393; doi:10.4049/jimmunol.0804307 [Abstract] [Full Text] [PDF] Data Supplement  

Shiga Toxin Activates Complement and Binds Factor H: Evidence for an Active Role of Complement in Hemolytic Uremic Syndrome

Dorothea Orth, Abdul Basit Khan, Asma Naim, Katharina Grif, Jens Brockmeyer, Helge Karch, Michael Joannidis, Simon J. Clark, Anthony J. Day, Sonja Fidanzi, Heribert Stoiber, Manfred P. Dierich, Lothar B. Zimmerhackl, and Reinhard Würzner
J Immunol 2009 182: 6394-6400; doi:10.4049/jimmunol.0900151 [Abstract] [Full Text] [PDF]  

IgE-FcRI Interactions Determine HIV Coreceptor Usage and Susceptibility to Infection during Ontogeny of Mast Cells

J. Bruce Sundstrom, Gregory A. Hair, Aftab A. Ansari, W. Evan Secor, Alasdair M. Gilfillan, Dean D. Metcalfe, and Arnold S. Kirshenbaum
J Immunol 2009 182: 6401-6409; doi:10.4049/jimmunol.0801481 [Abstract] [Full Text] [PDF]  

Impaired Priming and Activation of the Neutrophil NADPH Oxidase in Patients with IRAK4 or NEMO Deficiency

Anjali Singh, Kol A. Zarember, Douglas B. Kuhns, and John I. Gallin
J Immunol 2009 182: 6410-6417; doi:10.4049/jimmunol.0802512 [Abstract] [Full Text] [PDF]  

Trichothecene Mycotoxins Activate Inflammatory Response in Human Macrophages

Päivi Kankkunen, Johanna Rintahaka, Annika Aalto, Marina Leino, Marja-Leena Majuri, Harri Alenius, Henrik Wolff, and Sampsa Matikainen
J Immunol 2009 182: 6418-6425; doi:10.4049/jimmunol.0803309 [Abstract] [Full Text] [PDF]  

Killer Ig-Like Receptor (KIR) Genotype Predicts the Capacity of Human KIR-Positive CD56^dim NK Cells to Respond to Pathogen-Associated Signals

Daniel S. Korbel, Paul J. Norman, Kirsty C. Newman, Amir Horowitz, Ketevan Gendzekhadze, Peter Parham, and Eleanor M. Riley
J Immunol 2009 182: 6426-6434; doi:10.4049/jimmunol.0804224 [Abstract] [Full Text] [PDF] Data Supplement  

The Mucosal Adjuvant Effect of -Galactosylceramide for Induction of Protective Immunity to Sexually Transmitted Viral Infection

Madelene Lindqvist, Josefine Persson, Karolina Thörn, and Ali M. Harandi
J Immunol 2009 182: 6435-6443; doi:10.4049/jimmunol.0900136 [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Adiponectin Promotes Endotoxin Tolerance in Macrophages by Inducing IRAK-M Expression

Vassiliki Zacharioudaki, Ariadne Androulidaki, Alicia Arranz, George Vrentzos, Andrew N. Margioris, and Christos Tsatsanis
J Immunol 2009 182: 6444-6451; doi:10.4049/jimmunol.0803694 [Abstract] [Full Text] [PDF]  

Regulation of Helminth-Induced Th2 Responses by Thymic Stromal Lymphopoietin

Thirumalai R. Ramalingam, John T. Pesce, Margaret M. Mentink-Kane, Satish Madala, Allen W. Cheever, Michael R. Comeau, Steven F. Ziegler, and Thomas A. Wynn
J Immunol 2009 182: 6452-6459; doi:10.4049/jimmunol.0900181 [Abstract] [Full Text] [PDF]  

Neisseria gonorrhoeae Activates the Proteinase Cathepsin B to Mediate the Signaling Activities of the NLRP3 and ASC-Containing Inflammasome

Joseph A. Duncan, Xi Gao, Max Tze-Han Huang, Brian P. O'Connor, Christopher E. Thomas, Stephen B. Willingham, Daniel T. Bergstralh, Gary A. Jarvis, P. Frederick Sparling, and Jenny P.-Y. Ting
J Immunol 2009 182: 6460-6469; doi:10.4049/jimmunol.0802696 [Abstract] [Full Text] [PDF] Data Supplement  

Hypoxia-Inducible Factor (HIF) 1 Accumulation and HIF Target Gene Expression Are Impaired after Induction of Endotoxin Tolerance

Stilla Frede, Christian Stockmann, Sandra Winning, Patricia Freitag, and Joachim Fandrey
J Immunol 2009 182: 6470-6476; doi:10.4049/jimmunol.0802378 [Abstract] [Full Text] [PDF]  

IL-1R Type I-Dependent Hemopoietic Stem Cell Proliferation Is Necessary for Inflammatory Granulopoiesis and Reactive Neutrophilia

Yoshihiro Ueda, Derek W. Cain, Masayuki Kuraoka, Motonari Kondo, and Garnett Kelsoe
J Immunol 2009 182: 6477-6484; doi:10.4049/jimmunol.0803961 [Abstract] [Full Text] [PDF] Data Supplement  

Tetraspanin CD9 Negatively Regulates Lipopolysaccharide-Induced Macrophage Activation and Lung Inflammation

Mayumi Suzuki, Isao Tachibana, Yoshito Takeda, Ping He, Seigo Minami, Takeo Iwasaki, Hiroshi Kida, Sho Goya, Takashi Kijima, Mitsuhiro Yoshida, Toru Kumagai, Tadashi Osaki, and Ichiro Kawase
J Immunol 2009 182: 6485-6493; doi:10.4049/jimmunol.0802797 [Abstract] [Full Text] [PDF]  

Potent Phagocytic Activity with Impaired Antigen Presentation Identifying Lipopolysaccharide-Tolerant Human Monocytes: Demonstration in Isolated Monocytes from Cystic Fibrosis Patients

Carlos del Fresno, Francisco García-Rio, Vanesa Gómez-Piña, Alessandra Soares-Schanoski, Irene Fernández-Ruíz, Teresa Jurado, Tasneem Kajiji, Chen Shu, Elvira Marín, Ana Gutierrez del Arroyo, Concepción Prados, Francisco Arnalich, Pablo Fuentes-Prior, Subrha K. Biswas, and Eduardo López-Collazo
J Immunol 2009 182: 6494-6507; doi:10.4049/jimmunol.0803350 [Abstract] [Full Text] [PDF] Data Supplement  

Sialoadhesin-Positive Macrophages Bind Regulatory T Cells, Negatively Controlling Their Expansion and Autoimmune Disease Progression

Chuan Wu, Uwe Rauch, Eva Korpos, Jian Song, Karin Loser, Paul R. Crocker, and Lydia M. Sorokin
J Immunol 2009 182: 6508-6516; doi:10.4049/jimmunol.0804247 [Abstract] [Full Text] [PDF] Data Supplement  

FcRI and FcRIII/CD16 Differentially Regulate Atopic Dermatitis in Mice

Georges Abboud, Delphine Staumont-Sallé, Akira Kanda, Thomas Roumier, Nathalie Deruytter, Céline Lavogiez, Sébastien Fleury, Patrick Rémy, Jean-Paul Papin, Monique Capron, and David Dombrowicz
J Immunol 2009 182: 6517-6526; doi:10.4049/jimmunol.0801055 [Abstract] [Full Text] [PDF]  

RhoH/TTF Negatively Regulates Leukotriene Production in Neutrophils

Arezoo Daryadel, Shida Yousefi, David Troi, Inès Schmid, Jan Schmidt-Mende, Carlo Mordasini, Clemens A. Dahinden, Andrew Ziemiecki, and Hans-Uwe Simon
J Immunol 2009 182: 6527-6532; doi:10.4049/jimmunol.0803846 [Abstract] [Full Text] [PDF]  

Targeted Disruption of the Gene Encoding the Murine Small Subunit of Carboxypeptidase N (CPN1) Causes Susceptibility to C5a Anaphylatoxin-Mediated Shock

Stacey L. Mueller-Ortiz, Dachun Wang, John E. Morales, Li Li, Jui-Yoa Chang, and Rick A. Wetsel
J Immunol 2009 182: 6533-6539; doi:10.4049/jimmunol.0804207 [Abstract] [Full Text] [PDF]  

IL-17A-Expressing T Cells Are Essential for Bacterial Clearance in a Murine Model of Hypersensitivity Pneumonitis

Philip L. Simonian, Christina L. Roark, Fabian Wehrmann, Allison M. Lanham, Willi K. Born, Rebecca L. O'Brien, and Andrew P. Fontenot
J Immunol 2009 182: 6540-6549; doi:10.4049/jimmunol.0900013 [Abstract] [Full Text] [PDF]  

Lack of Functional P-Selectin Ligand Exacerbates Salmonella Serovar Typhimurium Infection

Winnie W. S. Kum, Sansan Lee, Guntram A. Grassl, Roza Bidshahri, Kimberly Hsu, Hermann J. Ziltener, and B. Brett Finlay
J Immunol 2009 182: 6550-6561; doi:10.4049/jimmunol.0802536 [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

IL4R⁺ Myeloid-Derived Suppressor Cell Expansion in Cancer Patients

Susanna Mandruzzato, Samantha Solito, Erika Falisi, Samuela Francescato, Vanna Chiarion-Sileni, Simone Mocellin, Antonio Zanon, Carlo R. Rossi, Donato Nitti, Vincenzo Bronte, and Paola Zanovello
J Immunol 2009 182: 6562-6568; doi:10.4049/jimmunol.0803831 [Abstract] [Full Text] [PDF]  

Antigen-Specific Blockade of Lethal CD8 T-Cell Mediated Autoimmunity in a Mouse Model of Multiple Sclerosis

Shin-Young Na, Heike Eujen, Kerstin Göbel, Sven G. Meuth, Kati Martens, Heinz Wiendl, and Thomas Hünig
J Immunol 2009 182: 6569-6575; doi:10.4049/jimmunol.0804200 [Abstract] [Full Text] [PDF] Data Supplement  

Neonatal Exposure to Low-Dose 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Causes Autoimmunity Due to the Disruption of T Cell Tolerance

Naozumi Ishimaru, Atsuya Takagi, Masayuki Kohashi, Akiko Yamada, Rieko Arakaki, Jun Kanno, and Yoshio Hayashi
J Immunol 2009 182: 6576-6586; doi:10.4049/jimmunol.0802289 [Abstract] [Full Text] [PDF]  

Adenovirus Vector-Induced Immune Responses in Nonhuman Primates: Responses to Prime Boost Regimens

Nia Tatsis, Marcio O. Lasaro, Shih-Wen Lin, Zhi Q. Xiang, Dongming Zhou, Lauren DiMenna, Hua Li, Ang Bian, Sarah Abdulla, Yan Li, Wynetta Giles-Davis, Jessica Engram, Sarah J. Ratcliffe, Guido Silvestri, Hildegund C. Ertl, and Michael R. Betts
J Immunol 2009 182: 6587-6599; doi:10.4049/jimmunol.0900317 [Abstract] [Full Text] [PDF]  

Proteasome Regulation of ULBP1 Transcription

James E. Butler, Mikel B. Moore, Steven R. Presnell, Huei-Wei Chan, N. Jan Chalupny, and Charles T. Lutz
J Immunol 2009 182: 6600-6609; doi:10.4049/jimmunol.0801214 [Abstract] [Full Text] [PDF]  

Vaccines Containing de-N-Acetyl Sialic Acid Elicit Antibodies Protective against Neisseria meningitidis Groups B and C

Gregory R. Moe, Tamara S. Bhandari, and Becca A. Flitter
J Immunol 2009 182: 6610-6617; doi:10.4049/jimmunol.0803677 [Abstract] [Full Text] [PDF]  

Human Pregnancy Up-Regulates Tim-3 in Innate Immune Cells for Systemic Immunity

Jie Zhao, Zhang Lei, Yanyan Liu, Bo Li, Liang Zhang, Haoshu Fang, Chuanwang Song, Xiaomei Wang, Gui-Mei Zhang, Zuo-Hua Feng, and Bo Huang
J Immunol 2009 182: 6618-6624; doi:10.4049/jimmunol.0803876 [Abstract] [Full Text] [PDF]  

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