IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2008 181: 5811-5812. [Full Text] [PDF] ImmunoCast  

LETTERS TO THE EDITOR:

Comment on "Chronic Alcohol Consumption Increases the Severity of Murine Influenza Virus Infections"

Jiezhong Chen
J Immunol 2008 181: 5813. [Full Text] [PDF]  

Response to Comment on "Chronic Alcohol Consumption Increases the Severity of Murine Influenza Virus Infections"

David K. Meyerholz, Michelle Edsen-Moore, Jodi McGill, Ruth A. Coleman, Robert T. Cook, and Kevin L. Legge
J Immunol 2008 181: 5813-5814. [Full Text] [PDF]  

PILLARS OF IMMUNOLOGY:

The "Bubble Boy" Paradox: An Answer That Led to a Question

Leslie J. Berg
J Immunol 2008 181: 5815-5816. [Full Text] [PDF] [Original Pillars Article]  

Pillars Article: Interleukin-2 Receptor Chain Mutation Results in X-Linked Severe Combined Immunodeficiency in Humans. Cell 73: 147–157.

Masayuki Noguchi, Huafang Yi, Howard M. Rosenblatt, Alexandra H. Filipovich, Stephen Adelstein, William S. Modi, O. Wesley McBride, and Warren J. Leonard
J Immunol 2008 181: 5817-5827. [PDF]  

BRIEF REVIEWS:

Macrophages as APC and the Dendritic Cell Myth

David A. Hume
J Immunol 2008 181: 5829-5835. [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: Local Recall Responses by Memory T Cells Newly Recruited to Peripheral Nonlymphoid Tissues

Linda M. Wakim, Thomas Gebhardt, William R. Heath, and Francis R. Carbone
J Immunol 2008 181: 5837-5841. [Abstract] [Full Text] [PDF]  

Cutting Edge: IFN- Enables APC to Promote Memory Th17 and Abate Th1 Cell Development

Ilona Kryczek, Shuang Wei, Wenrong Gong, Xiaogong Shu, Wojciech Szeliga, Linhua Vatan, Lieping Chen, Guobin Wang, and Weiping Zou
J Immunol 2008 181: 5842-5846. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Jakmip1 Is Expressed upon T Cell Differentiation and Has an Inhibitory Function in Cytotoxic T Lymphocytes

Valentina Libri, Dörte Schulte, Amber van Stijn, Josiane Ragimbeau, Lars Rogge, and Sandra Pellegrini
J Immunol 2008 181: 5847-5856. [Abstract] [Full Text] [PDF]  

NF-B Modulates Sensitivity to Apoptosis, Proinflammatory and Migratory Potential in Short- versus Long-Term Cultured Human Lymphocytes

Marina Ferrarini, Fanny Delfanti, Monica Gianolini, Chiara Rizzi, Massimo Alfano, Adriano Lazzarin, and Priscilla Biswas
J Immunol 2008 181: 5857-5864. [Abstract] [Full Text] [PDF]  

A Complex Interplay among Virus, Dendritic Cells, T Cells, and Cytokines in Dengue Virus Infections

Wanwisa Dejnirattisai, Thaneeya Duangchinda, Chen-Lung Steve Lin, Sirijitt Vasanawathana, Meleri Jones, Michael Jacobs, Prida Malasit, Xiao-ning Xu, Gavin Screaton, and Juthathip Mongkolsapaya
J Immunol 2008 181: 5865-5874. [Abstract] [Full Text] [PDF]  

Autoreactive B Cells Discriminate CpG-Rich and CpG-Poor DNA and This Response Is Modulated by IFN-

Melissa B. Uccellini, Liliana Busconi, Nathaniel M. Green, Patricia Busto, Sean R. Christensen, Mark J. Shlomchik, Ann Marshak-Rothstein, and Gregory A. Viglianti
J Immunol 2008 181: 5875-5884. [Abstract] [Full Text] [PDF]  

E47 Controls the Developmental Integrity and Cell Cycle Quiescence of Multipotential Hematopoietic Progenitors

Qi Yang, Lela Kardava, Anthony St. Leger, Kathleen Martincic, Barbara Varnum-Finney, Irwin D. Bernstein, Christine Milcarek, and Lisa Borghesi
J Immunol 2008 181: 5885-5894. [Abstract] [Full Text] [PDF]  

Pathogenic Effector T Cell Enrichment Overcomes Regulatory T Cell Control and Generates Autoimmune Gastritis

João P. Monteiro, Julia Farache, Ana Carolina Mercadante, Julio A. Mignaco, Martin Bonamino, and Adriana Bonomo
J Immunol 2008 181: 5895-5903. [Abstract] [Full Text] [PDF]  

A Quantitative Trait Locus on Chromosome 4 Affects Cycling of Hematopoietic Stem and Progenitor Cells through Regulation of TGF-β2 Responsiveness

Serine Avagyan, Ludmila Glouchkova, Juhyun Choi, and Hans-Willem Snoeck
J Immunol 2008 181: 5904-5911. [Abstract] [Full Text] [PDF] Data Supplement  

Fas Expression on Antigen-Specific T Cells Has Costimulatory, Helper, and Down-Regulatory Functions In Vivo for Cytotoxic T Cell Responses but Not for T Cell-Dependent B Cell Responses

Irina Puliaeva, Roman Puliaev, Andrei Shustov, Mark Haas, and Charles S. Via
J Immunol 2008 181: 5912-5929. [Abstract] [Full Text] [PDF]  

SIT and TRIM Determine T Cell Fate in the Thymus

Uwe Koelsch, Burkhart Schraven, and Luca Simeoni
J Immunol 2008 181: 5930-5939. [Abstract] [Full Text] [PDF]  

Identification of CD25⁺ T Cells As Fetal Thymus-Derived Naturally Occurring IL-17 Producers

Kensuke Shibata, Hisakata Yamada, Risa Nakamura, Xun Sun, Momoe Itsumi, and Yasunobu Yoshikai
J Immunol 2008 181: 5940-5947. [Abstract] [Full Text] [PDF]  

IL-23 Promotes Maintenance but Not Commitment to the Th17 Lineage

Gretta L. Stritesky, Norman Yeh, and Mark H. Kaplan
J Immunol 2008 181: 5948-5955. [Abstract] [Full Text] [PDF]  

Experimental Extracorporeal Photopheresis Inhibits the Sensitization and Effector Phases of Contact Hypersensitivity via Two Mechanisms: Generation of IL-10 and Induction of Regulatory T Cells

Akira Maeda, Agatha Schwarz, Ann Bullinger, Akimichi Morita, David Peritt, and Thomas Schwarz
J Immunol 2008 181: 5956-5962. [Abstract] [Full Text] [PDF]  

Rho-ROCK-Dependent Ezrin-Radixin-Moesin Phosphorylation Regulates Fas-Mediated Apoptosis in Jurkat Cells

Marylise Hébert, Sophie Potin, Michaël Sebbagh, Jacques Bertoglio, Jacqueline Bréard, and Jocelyne Hamelin
J Immunol 2008 181: 5963-5973. [Abstract] [Full Text] [PDF]  

Heterospecific CD4 Help to Rescue CD8 T Cell Killers

Marie-Ghislaine de Goër de Herve, Anne Cariou, Federico Simonetta, and Yassine Taoufik
J Immunol 2008 181: 5974-5980. [Abstract] [Full Text] [PDF]  

An IL-1 Cytokine Member, IL-33, Induces Human Basophil Activation via Its ST2 Receptor

Maho Suzukawa, Motoyasu Iikura, Rikiya Koketsu, Hiroyuki Nagase, Chise Tamura, Akiko Komiya, Susumu Nakae, Kouji Matsushima, Ken Ohta, Kazuhiko Yamamoto, and Masao Yamaguchi
J Immunol 2008 181: 5981-5989. [Abstract] [Full Text] [PDF]  

OX40 Costimulatory Signals Potentiate the Memory Commitment of Effector CD8⁺ T Cells

Seyed Fazlollah Mousavi, Pejman Soroosh, Takeshi Takahashi, Yasunobu Yoshikai, Hao Shen, Leo Lefrançois, Jannie Borst, Kazuo Sugamura, and Naoto Ishii
J Immunol 2008 181: 5990-6001. [Abstract] [Full Text] [PDF]  

TCR Complex-Activated CD8 Adhesion Function by Human T Cells

Jay C. Varghese and Kevin P. Kane
J Immunol 2008 181: 6002-6009. [Abstract] [Full Text] [PDF]  

Estimation of the Size of the Alloreactive NK Cell Repertoire: Studies in Individuals Homozygous for the Group A KIR Haplotype

Cyril Fauriat, Sandra Andersson, Andreas T. Björklund, Mattias Carlsten, Marie Schaffer, Niklas K. Björkström, Bettina C. Baumann, Jakob Michaëlsson, Hans-Gustaf Ljunggren, and Karl-Johan Malmberg
J Immunol 2008 181: 6010-6019. [Abstract] [Full Text] [PDF]  

Calcitonin Gene-Related Peptide Biases Langerhans Cells toward Th2-Type Immunity

Wanhong Ding, Lori L. Stohl, John A. Wagner, and Richard D. Granstein
J Immunol 2008 181: 6020-6026. [Abstract] [Full Text] [PDF]  

Intraclonal Competition Inhibits the Formation of High-Affinity Antibody-Secreting Cells

Thuc-vy L. Le, Tea Hyun Kim, and David D. Chaplin
J Immunol 2008 181: 6027-6037. [Abstract] [Full Text] [PDF]  

Nasal Anti-CD3 Antibody Ameliorates Lupus by Inducing an IL-10-Secreting CD4⁺CD25^–LAP⁺ Regulatory T Cell and Is Associated with Down-Regulation of IL-17⁺CD4⁺ICOS⁺CXCR5⁺ Follicular Helper T Cells

Henry Yim Wu, Francisco J. Quintana, and Howard L. Weiner
J Immunol 2008 181: 6038-6050. [Abstract] [Full Text] [PDF]  

IL-24 Induces Apoptosis of Chronic Lymphocytic Leukemia B Cells Engaged into the Cell Cycle through Dephosphorylation of STAT3 and Stabilization of p53 Expression

Alexander Sainz-Perez, Hélène Gary-Gouy, Françoise Gaudin, Ghyath Maarof, Anne Marfaing-Koka, Thierry de Revel, and Ali Dalloul
J Immunol 2008 181: 6051-6060. [Abstract] [Full Text] [PDF]  

Soluble Frizzled-Related Protein 1 Is Estrogen Inducible in Bone Marrow Stromal Cells and Suppresses the Earliest Events in Lymphopoiesis

Takafumi Yokota, Kenji Oritani, Karla P. Garrett, Taku Kouro, Makoto Nishida, Isao Takahashi, Michiko Ichii, Yusuke Satoh, Paul W. Kincade, and Yuzuru Kanakura
J Immunol 2008 181: 6061-6072. [Abstract] [Full Text] [PDF]  

Anterior Pituitary Progenitor Cells Express Costimulatory Molecule 4Ig-B7-H3

Yasuhiro Nagai, Hisashi Aso, Hideki Ogasawara, Sachi Tanaka, Yoshikazu Taketa, Kouichi Watanabe, Shyuichi Ohwada, Michael T. Rose, Haruki Kitazawa, and Takahiro Yamaguchi
J Immunol 2008 181: 6073-6081. [Abstract] [Full Text] [PDF]  

Selective Regulation of TCR Signaling Pathways by the CD45 Protein Tyrosine Phosphatase during Thymocyte Development

Rustom Falahati and David Leitenberg
J Immunol 2008 181: 6082-6091. [Abstract] [Full Text] [PDF]  

Central Tolerance Regulates B Cells Reactive with Goodpasture Antigen 3(IV)NC1 Collagen

Ying Zhang, Susan C. Su, Douglas B. Hecox, Graham F. Brady, Katherine M. Mackin, Amy G. Clark, and Mary H. Foster
J Immunol 2008 181: 6092-6100. [Abstract] [Full Text] [PDF]  

An Epithelial Progenitor Pool Regulates Thymus Growth

William E. Jenkinson, Andrea Bacon, Andrea J. White, Graham Anderson, and Eric J. Jenkinson
J Immunol 2008 181: 6101-6108. [Abstract] [Full Text] [PDF]  

Expression of CD86 on Human Islet Endothelial Cells Facilitates T Cell Adhesion and Migration

Biliana Lozanoska-Ochser, Nigel J. Klein, Guo C. Huang, Raymond A. Alvarez, and Mark Peakman
J Immunol 2008 181: 6109-6116. [Abstract] [Full Text] [PDF]  

IL-17-Producing Alveolar Macrophages Mediate Allergic Lung Inflammation Related to Asthma

Chuanwang Song, Liqiong Luo, Zhang Lei, Bo Li, Zhihui Liang, Guanghui Liu, Dong Li, Guimei Zhang, Bo Huang, and Zuo-Hua Feng
J Immunol 2008 181: 6117-6124. [Abstract] [Full Text] [PDF]  

Selective Expression Rather than Specific Function of Txk and Itk Regulate Th1 and Th2 Responses

Nisebita Sahu, Ana M. Venegas, Dragana Jankovic, Wayne Mitzner, Julio Gomez-Rodriguez, Jennifer L. Cannons, Connie Sommers, Paul Love, Alan Sher, Pamela L. Schwartzberg, and Avery August
J Immunol 2008 181: 6125-6131. [Abstract] [Full Text] [PDF] Data Supplement  

Critical Role of TLR9 in Acute Graft-versus-Host Disease

Claudia Calcaterra, Lucia Sfondrini, Anna Rossini, Michele Sommariva, Cristiano Rumio, Sylvie Ménard, and Andrea Balsari
J Immunol 2008 181: 6132-6139. [Abstract] [Full Text] [PDF] Data Supplement  

Unique Receptor Repertoire in Mouse Uterine NK cells

Hakim Yadi, Shannon Burke, Zofia Madeja, Myriam Hemberger, Ashley Moffett, and Francesco Colucci
J Immunol 2008 181: 6140-6147. [Abstract] [Full Text] [PDF]  

Immunosurveillance of Lung Melanoma Metastasis in EBI-3-Deficient Mice Mediated by CD8⁺ T Cells

Kerstin A. Sauer, Joachim H. Maxeiner, Roman Karwot, Petra Scholtes, Hans A. Lehr, Mark Birkenbach, Richard S. Blumberg, and Susetta Finotto
J Immunol 2008 181: 6148-6157. [Abstract] [Full Text] [PDF]  

Cross-Linking of B7-H1 on EBV-Transformed B Cells Induces Apoptosis through Reactive Oxygen Species Production, JNK Signaling Activation, and fasL Expression

Yeong Seok Kim, Ga Bin Park, Hyun-Kyung Lee, Hyunkeun Song, In-Hak Choi, Wang Jae Lee, and Dae Young Hur
J Immunol 2008 181: 6158-6169. [Abstract] [Full Text] [PDF] Data Supplement  

Human NK Cells Kill Resting but Not Activated Microglia via NKG2D- and NKp46-Mediated Recognition

Anna Lünemann, Jan D. Lünemann, Susanne Roberts, Brady Messmer, Rosa Barreira da Silva, Cedric S. Raine, and Christian Münz
J Immunol 2008 181: 6170-6177. [Abstract] [Full Text] [PDF]  

CX₃CR1⁺c-kit⁺ Bone Marrow Cells Give Rise to CD103⁺ and CD103^– Dendritic Cells with Distinct Functional Properties

Maria-Luisa del Rio, Jose-Ignacio Rodriguez-Barbosa, Jasmin Bölter, Matthias Ballmaier, Oliver Dittrich-Breiholz, Michael Kracht, Steffen Jung, and Reinhold Förster
J Immunol 2008 181: 6178-6188. [Abstract] [Full Text] [PDF]  

Organizer-Like Reticular Stromal Cell Layer Common to Adult Secondary Lymphoid Organs

Tomoya Katakai, Hidenori Suto, Manabu Sugai, Hiroyuki Gonda, Atsushi Togawa, Sachiko Suematsu, Yukihiko Ebisuno, Koko Katagiri, Tatsuo Kinashi, and Akira Shimizu
J Immunol 2008 181: 6189-6200. [Abstract] [Full Text] [PDF] Data Supplement  

Mycobacterium bovis Bacille Calmette-Guérin Infection in the CNS Suppresses Experimental Autoimmune Encephalomyelitis and Th17 Responses in an IFN--Independent Manner

JangEun Lee, Emily K. Reinke, Alla L. Zozulya, Matyas Sandor, and Zsuzsanna Fabry
J Immunol 2008 181: 6201-6212. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Engineering Antibody Heavy Chain CDR3 to Create a Phage Display Fab Library Rich in Antibodies That Bind Charged Carbohydrates

Sonia Schoonbroodt, Mieke Steukers, Malini Viswanathan, Nicolas Frans, Marie Timmermans, Anita Wehnert, Minh Nguyen, Robert Charles Ladner, and René M. Hoet
J Immunol 2008 181: 6213-6221. [Abstract] [Full Text] [PDF]  

Transcription Factor Gfi1 Restricts B Cell-Mediated Autoimmunity

Chozhavendan Rathinam, Hans Lassmann, Michael Mengel, and Christoph Klein
J Immunol 2008 181: 6222-6229. [Abstract] [Full Text] [PDF] Data Supplement  

Automated Identification of Complementarity Determining Regions (CDRs) Reveals Peculiar Characteristics of CDRs and B Cell Epitopes

Yanay Ofran, Avner Schlessinger, and Burkhard Rost
J Immunol 2008 181: 6230-6235. [Abstract] [Full Text] [PDF]  

n-3 Polyunsaturated Fatty Acids Suppress the Localization and Activation of Signaling Proteins at the Immunological Synapse in Murine CD4⁺ T Cells by Affecting Lipid Raft Formation

Wooki Kim, Yang-Yi Fan, Rola Barhoumi, Roger Smith, David N. McMurray, and Robert S. Chapkin
J Immunol 2008 181: 6236-6243. [Abstract] [Full Text] [PDF]  

Loss of Protein Kinase C, Bcl10, or Malt1 Selectively Impairs Proliferation and NF-B Activation in the CD4⁺ T Cell Subset

Lara M. Kingeter and Brian C. Schaefer
J Immunol 2008 181: 6244-6254. [Abstract] [Full Text] [PDF]  

Distinct CDR3 Conformations in TCRs Determine the Level of Cross-Reactivity for Diverse Antigens, but Not the Docking Orientation

Lindsay L. Jones, Leremy A. Colf, Jennifer D. Stone, K. Christopher Garcia, and David M. Kranz
J Immunol 2008 181: 6255-6264. [Abstract] [Full Text] [PDF] Data Supplement  

Ikaros Regulates Notch Target Gene Expression in Developing Thymocytes

Sheila Chari and Susan Winandy
J Immunol 2008 181: 6265-6274. [Abstract] [Full Text] [PDF]  

Endoplasmic Reticulum Aminopeptidase Associated with Antigen Processing Regulates Quality of Processed Peptides Presented by MHC Class I Molecules

Takayuki Kanaseki and Nilabh Shastri
J Immunol 2008 181: 6275-6282. [Abstract] [Full Text] [PDF]  

IMMUNOGENETICS:

Impact of Protective IL-2 Allelic Variants on CD4⁺Foxp3⁺ Regulatory T Cell Function In Situ and Resistance to Autoimmune Diabetes in NOD Mice

Evridiki Sgouroudis, Alexandre Albanese, and Ciriaco A. Piccirillo
J Immunol 2008 181: 6283-6292. [Abstract] [Full Text] [PDF]  

Polymorphic Sites Away from the Bw4 Epitope That Affect Interaction of Bw4⁺ HLA-B with KIR3DL1

Bharati Sanjanwala, Monia Draghi, Paul J. Norman, Lisbeth A. Guethlein, and Peter Parham
J Immunol 2008 181: 6293-6300. [Abstract] [Full Text] [PDF]  

Complete Characterization of Killer Ig-Like Receptor (KIR) Haplotypes in Mauritian Cynomolgus Macaques: Novel Insights into Nonhuman Primate KIR Gene Content and Organization

Benjamin N. Bimber, Anna J. Moreland, Roger W. Wiseman, Austin L. Hughes, and David H. O'Connor
J Immunol 2008 181: 6301-6308. [Abstract] [Full Text] [PDF] Data Supplement  

HOST DEFENSE:

An Indispensable Role for the Chemokine Receptor CCR10 in IgA Antibody-Secreting Cell Accumulation

Olivier Morteau, Craig Gerard, Bao Lu, Sorina Ghiran, Miriam Rits, Yuko Fujiwara, Yuetching Law, Kathryn Distelhorst, Elizabeth M. Nielsen, Erica D. Hill, Raymond Kwan, Nicole H. Lazarus, Eugene C. Butcher, and Eric Wilson
J Immunol 2008 181: 6309-6315. [Abstract] [Full Text] [PDF]  

A Novel Role of CD30L/CD30 Signaling by T-T Cell Interaction in Th1 Response against Mycobacterial Infection

Ce Tang, Hisakata Yamada, Kensuke Shibata, Hiromi Muta, Worawidh Wajjwalku, Eckhard R. Podack, and Yasunobu Yoshikai
J Immunol 2008 181: 6316-6327. [Abstract] [Full Text] [PDF]  

Immune Evasion of Enterococcus faecalis by an Extracellular Gelatinase That Cleaves C3 and iC3b

Shin Yong Park, Yong Pyo Shin, Chong Han Kim, Ho Jin Park, Yeon Sun Seong, Byung Sam Kim, Sook Jae Seo, and In Hee Lee
J Immunol 2008 181: 6328-6336. [Abstract] [Full Text] [PDF]  

Prior Immunization with Severe Acute Respiratory Syndrome (SARS)-Associated Coronavirus (SARS-CoV) Nucleocapsid Protein Causes Severe Pneumonia in Mice Infected with SARS-CoV

Fumihiko Yasui, Chieko Kai, Masahiro Kitabatake, Shingo Inoue, Misako Yoneda, Shoji Yokochi, Ryoichi Kase, Satoshi Sekiguchi, Kouichi Morita, Tsunekazu Hishima, Hidenori Suzuki, Katsuo Karamatsu, Yasuhiro Yasutomi, Hisatoshi Shida, Minoru Kidokoro, Kyosuke Mizuno, Kouji Matsushima, and Michinori Kohara
J Immunol 2008 181: 6337-6348. [Abstract] [Full Text] [PDF]  

Tuberculosis Triggers a Tissue-Dependent Program of Differentiation and Acquisition of Effector Functions by Circulating Monocytes

Markus Sköld and Samuel M. Behar
J Immunol 2008 181: 6349-6360. [Abstract] [Full Text] [PDF]  

Design, Expression, and Processing of Epitomized Hepatitis C Virus-Encoded CTL Epitopes

Daniel Yerly, David Heckerman, Todd Allen, Todd J. Suscovich, Nebojsa Jojic, Carl Kadie, Werner J. Pichler, Andreas Cerny, and Christian Brander
J Immunol 2008 181: 6361-6370. [Abstract] [Full Text] [PDF]  

Long-Term Immunity against Actual Poxviral HLA Ligands as Identified by Differential Stable Isotope Labeling

Verena S. Meyer, Wolfgang Kastenmuller, Georg Gasteiger, Mirita Franz-Wachtel, Tobias Lamkemeyer, Hans-Georg Rammensee, Stefan Stevanovic, Dagmar Sigurdardottir, and Ingo Drexler
J Immunol 2008 181: 6371-6383. [Abstract] [Full Text] [PDF]  

CCL3-CCR5 Axis Regulates Intratumoral Accumulation of Leukocytes and Fibroblasts and Promotes Angiogenesis in Murine Lung Metastasis Process

Yu Wu, Ying-Yi Li, Kouji Matsushima, Tomohisa Baba, and Naofumi Mukaida
J Immunol 2008 181: 6384-6393. [Abstract] [Full Text] [PDF] Data Supplement  

Ly49h-Deficient C57BL/6 Mice: A New Mouse Cytomegalovirus-Susceptible Model Remains Resistant to Unrelated Pathogens Controlled by the NK Gene Complex

Nassima Fodil-Cornu, Seung-Hwan Lee, Simon Belanger, Andrew P. Makrigiannis, Christine A. Biron, R. Mark Buller, and Silvia M. Vidal
J Immunol 2008 181: 6394-6405. [Abstract] [Full Text] [PDF]  

Cannabinoids Inhibit HIV-1 Gp120-Mediated Insults in Brain Microvascular Endothelial Cells

Tzong-Shi Lu, Hava Karsenty Avraham, Seyha Seng, Souvenir D. Tachado, Henry Koziel, Alexandros Makriyannis, and Shalom Avraham
J Immunol 2008 181: 6406-6416. [Abstract] [Full Text] [PDF]  

Prolonged Microglial Cell Activation and Lymphocyte Infiltration following Experimental Herpes Encephalitis

Cristina P. Marques, Maxim C-J. Cheeran, Joseph M. Palmquist, Shuxian Hu, Stina L. Urban, and James R. Lokensgard
J Immunol 2008 181: 6417-6426. [Abstract] [Full Text] [PDF]  

Receptor-Interacting Protein Homotypic Interaction Motif-Dependent Control of NF-B Activation via the DNA-Dependent Activator of IFN Regulatory Factors

William J. Kaiser, Jason W. Upton, and Edward S. Mocarski
J Immunol 2008 181: 6427-6434. [Abstract] [Full Text] [PDF]  

Hepatitis C Virus Immune Escape via Exploitation of a Hole in the T Cell Repertoire

Matthias Wölfl, Alleluiah Rutebemberwa, Timothy Mosbruger, Qing Mao, Hong-mei Li, Dale Netski, Stuart C. Ray, Drew Pardoll, John Sidney, Alessandro Sette, Todd Allen, Thomas Kuntzen, Daniel G. Kavanagh, Jürgen Kuball, Philip D. Greenberg, and Andrea L. Cox
J Immunol 2008 181: 6435-6446. [Abstract] [Full Text] [PDF] Data Supplement  

MyD88 Signaling Is Not Essential for Induction of Antigen-Specific B Cell Responses but Is Indispensable for Protection against Streptococcus pneumoniae Infection following Oral Vaccination with Attenuated Salmonella Expressing PspA Antigen

Sung-Moo Park, Hyun-Jeong Ko, Doo-Hee Shim, Jin-Young Yang, Yong-Ho Park, Roy Curtiss, III, and Mi-Na Kweon
J Immunol 2008 181: 6447-6455. [Abstract] [Full Text] [PDF]  

Expansion of Foxp3⁺ Regulatory T Cells in Mice Infected with the Filarial Parasite Brugia malayi

Henry J. McSorley, Yvonne M. Harcus, Janice Murray, Matthew D. Taylor, and Rick M. Maizels
J Immunol 2008 181: 6456-6466. [Abstract] [Full Text] [PDF]  

The Level of Hepatitis B Virus Replication Is Not Affected by Protein ISG15 Modification but Is Reduced by Inhibition of UBP43 (USP18) Expression

Jung-Hwan Kim, Jiann-Kae Luo, and Dong-Er Zhang
J Immunol 2008 181: 6467-6472. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Functional Dichotomy of Dendritic Cells following Interaction with Leishmania braziliensis: Infected Cells Produce High Levels of TNF-, whereas Bystander Dendritic Cells Are Activated to Promote T Cell Responses

Lucas P. Carvalho, Edward J. Pearce, and Phillip Scott
J Immunol 2008 181: 6473-6480. [Abstract] [Full Text] [PDF]  

Signaling through MyD88 Regulates Leukocyte Recruitment after Brain Injury

Alicia A. Babcock, Henrik Toft-Hansen, and Trevor Owens
J Immunol 2008 181: 6481-6490. [Abstract] [Full Text] [PDF]  

Zinc Signals Are Essential for Lipopolysaccharide-Induced Signal Transduction in Monocytes

Hajo Haase, Julia L. Ober-Blöbaum, Gabriela Engelhardt, Silke Hebel, Antje Heit, Holger Heine, and Lothar Rink
J Immunol 2008 181: 6491-6502. [Abstract] [Full Text] [PDF]  

IL-4-Induced Selective Clearance of Oligomeric β-Amyloid Peptide_1–42 by Rat Primary Type 2 Microglia

Eisuke Shimizu, Kohichi Kawahara, Makoto Kajizono, Makoto Sawada, and Hitoshi Nakayama
J Immunol 2008 181: 6503-6513. [Abstract] [Full Text] [PDF]  

12/15-Lipoxygenase Regulates the Inflammatory Response to Bacterial Products In Vivo

Vincent Dioszeghy, Marcela Rosas, Benjamin H. Maskrey, Chantal Colmont, Nicholas Topley, Pavlos Chaitidis, Hartmut Kühn, Simon A. Jones, Philip R. Taylor, and Valerie B. O'Donnell
J Immunol 2008 181: 6514-6524. [Abstract] [Full Text] [PDF]  

Human Plasmacytoid Dendritic Cells Interact with gp96 via CD91 and Regulate Inflammatory Responses

AnnaMaria De Filippo, Robert J. Binder, Chiara Camisaschi, Valeria Beretta, Flavio Arienti, Antonello Villa, Pamela Della Mina, Giorgio Parmiani, Licia Rivoltini, and Chiara Castelli
J Immunol 2008 181: 6525-6535. [Abstract] [Full Text] [PDF]  

Differential Regulation of Chemokines by IL-17 in Colonic Epithelial Cells

Jimmy W. Lee, Ping Wang, Michael G. Kattah, Sawsan Youssef, Lawrence Steinman, Kathryn DeFea, and Daniel S. Straus
J Immunol 2008 181: 6536-6545. [Abstract] [Full Text] [PDF]  

CCR5 Deficiency Aggravates Crescentic Glomerulonephritis in Mice

Jan-Eric Turner, Hans-Joachim Paust, Oliver M. Steinmetz, Anett Peters, Catherine Meyer-Schwesinger, Felix Heymann, Udo Helmchen, Susanne Fehr, Richard Horuk, Ulrich Wenzel, Christian Kurts, Hans-Willi Mittrücker, Rolf A. K. Stahl, and Ulf Panzer
J Immunol 2008 181: 6546-6556. [Abstract] [Full Text] [PDF]  

Reversal of Thymic Stromal Lymphopoietin-Induced Airway Inflammation through Inhibition of Th2 Responses

Baohua Zhou, Mark B. Headley, Theingi Aye, Joel Tocker, Michael R. Comeau, and Steven F. Ziegler
J Immunol 2008 181: 6557-6562. [Abstract] [Full Text] [PDF]  

Activation of an Immunoregulatory and Antiviral Gene Expression Program in Poly(I:C)-Transfected Human Neutrophils

Nicola Tamassia, Vincent Le Moigne, Marzia Rossato, Marta Donini, Stephen McCartney, Federica Calzetti, Marco Colonna, Flavia Bazzoni, and Marco A. Cassatella
J Immunol 2008 181: 6563-6573. [Abstract] [Full Text] [PDF]  

Analysis of CD97 Expression and Manipulation: Antibody Treatment but Not Gene Targeting Curtails Granulocyte Migration

Henrike Veninga, Susann Becker, Robert M. Hoek, Manja Wobus, Elke Wandel, Jos van der Kaa, Martin van der Valk, Alex F. de Vos, Hannelore Haase, Bronwyn Owens, Tom van der Poll, René A. W. van Lier, J. Sjef Verbeek, Gabriela Aust, and Jörg Hamann
J Immunol 2008 181: 6574-6583. [Abstract] [Full Text] [PDF]  

Up-Regulation of Vascular Endothelial Growth Factor-D Expression in Clear Cell Renal Cell Carcinoma by CD74: A Critical Role in Cancer Cell Tumorigenesis

Yu-Huei Liu, Chang-Yueh Lin, Wei-Chou Lin, Sai-Wen Tang, Ming-Kuen Lai, and Jung-Yaw Lin
J Immunol 2008 181: 6584-6594. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Carcinoembryonic Antigen-Specific but Not Antiviral CD4⁺ T Cell Immunity Is Impaired in Pancreatic Carcinoma Patients

Elena Tassi, Francesca Gavazzi, Luca Albarello, Vladimir Senyukov, Renato Longhi, Paolo Dellabona, Claudio Doglioni, Marco Braga, Valerio Di Carlo, and Maria Pia Protti
J Immunol 2008 181: 6595-6603. [Abstract] [Full Text] [PDF]  

Immunodominant Epitopes in Herpes Simplex Virus Type 2 Glycoprotein D Are Recognized by CD4 Lymphocytes from Both HSV-1 and HSV-2 Seropositive Subjects

Min Kim, Janette Taylor, John Sidney, Zorka Mikloska, Neil Bodsworth, Katerina Lagios, Heather Dunckley, Karen Byth-Wilson, Martine Denis, Robert Finlayson, Rajiv Khanna, Alessandro Sette, and Anthony L. Cunningham
J Immunol 2008 181: 6604-6615. [Abstract] [Full Text] [PDF]  

Strategic Nonmyeloablative Conditioning: CD154:CD40 Costimulatory Blockade at Primary Bone Marrow Transplantation Promotes Engraftment for Secondary Bone Marrow Transplantation after Engraftment Failure

Hong Xu, Yiming Huang, Paula M. Chilton, Lala-Rukh Hussain, Michael K. Tanner, Jun Yan, and Suzanne T. Ildstad
J Immunol 2008 181: 6616-6624. [Abstract] [Full Text] [PDF]  

Characterization of the Antibody Response against NeuGcGM3 Ganglioside Elicited in Non-Small Cell Lung Cancer Patients Immunized with an Anti-Idiotype Antibody

Ana María Hernández, Darién Toledo, Darel Martínez, Tania Griñán, Victor Brito, Amparo Macías, Sailyn Alfonso, Teresa Rondón, Eduardo Suárez, Ana María Vázquez, and Rolando Pérez
J Immunol 2008 181: 6625-6634. [Abstract] [Full Text] [PDF]  

Activation of Antigen-Specific Cytotoxic T Lymphocytes by β₂-Microglobulin or TAP1 Gene Disruption and the Introduction of Recipient-Matched MHC Class I Gene in Allogeneic Embryonic Stem Cell-Derived Dendritic Cells

Yusuke Matsunaga, Daiki Fukuma, Shinya Hirata, Satoshi Fukushima, Miwa Haruta, Tokunori Ikeda, Izumi Negishi, Yasuharu Nishimura, and Satoru Senju
J Immunol 2008 181: 6635-6643. [Abstract] [Full Text] [PDF]  

Immunization with a Mimotope of GD2 Ganglioside Induces CD8⁺ T Cells That Recognize Cell Adhesion Molecules on Tumor Cells

Andrzej Wierzbicki, Margaret Gil, Michael Ciesielski, Robert A. Fenstermaker, Yutaro Kaneko, Hanna Rokita, Joseph T. Lau, and Danuta Kozbor
J Immunol 2008 181: 6644-6653. [Abstract] [Full Text] [PDF]  

Bone Marrow-Derived IFN-Producing Killer Dendritic Cells Account for the Tumoricidal Activity of Unpulsed Dendritic Cells

Nourredine Himoudi, Stephen Nabarro, Jo Buddle, Ayad Eddaoudi, Adrian J. Thrasher, and John Anderson
J Immunol 2008 181: 6654-6663. [Abstract] [Full Text] [PDF]  

Crucial Role of Aspartic Acid at Position 265 in the CH2 Domain for Murine IgG2a and IgG2b Fc-Associated Effector Functions

Lucie Baudino, Yasuro Shinohara, Falk Nimmerjahn, Jun-Ichi Furukawa, Munehiro Nakata, Eduardo Martínez-Soria, Franz Petry, Jeffery V. Ravetch, Shin-Ichiro Nishimura, and Shozo Izui
J Immunol 2008 181: 6664-6669. [Abstract] [Full Text] [PDF]  

LETTERS OF RETRACTION:

Retraction: Dual Effect of AMD3100, a CXCR4 Antagonist, on Bleomycin-Indiced Lung Inflammation

Masaki Watanabe, Yuko Shirahama, Hideo Mitsuyama, Ken-ichi Oonakahara, Satoshi Noma, Ikkou Higashimoto, Mitsuhiro Osame, and Kimiyoshi Arimura
J Immunol 2008 181: 6670. [Full Text] [PDF]  

Retraction: Suppression of Discoidin Domain Receptor 1 by RNA Interference Attenuates Lung Inflammation

Masaki Watanabe, Yuko Shirahama, Ryuki Hirano, Hideo Mitsuyama, Ikkou Higashimoto, Mitsuhiro Osame, and Kimiyoshi Arimura
J Immunol 2008 181: 6671. [Full Text] [PDF]  

Retraction: Activation of Discoidin Domain Receptor 1 on CD14-Positive Bronchoalveolar Lavage Fluid Cells Induces Chemokine Production in Idiopathic Fibrosis

Masaki Watanabe, Yuko Shirahama, Ken-ichi Oonakahara, Ikkou Higashimoto, Mitsuhiro Osame, Kimiyoshi Arimura, and Teizo Yoshimura
J Immunol 2008 181: 6672. [Full Text] [PDF]  

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