IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2008 180: 5759-5760. [Full Text] [PDF]  

LETTERS TO THE EDITOR:

Comment on "Cigarette Smoke-Induced Pulmonary Inflammation Is TLR4/MyD88 and IL-1R1/MyD88 Signaling Dependent"

Tania Maes, Ken R. Bracke, Guy F. Joos, and Guy G. Brusselle
J Immunol 2008 180: 5761. [Full Text] [PDF]  

Response to Comment on "Cigarette Smoke-Induced Pulmonary Inflammation Is TLR4/MyD88 and IL-1R1/MyD88 Signaling Dependent"

Emilie Doz, Bernhard Ryffel, Valérie F. J. Quesniaux, and Isabelle Couillin
J Immunol 2008 180: 5761. [Full Text] [PDF]  

PILLARS OF IMMUNOLOGY:

Tracking and Trapping Somatic Mutations in Ig Genes

Marko Radic
J Immunol 2008 180: 5763-5764. [Full Text] [PDF]  

Pillars Article: Generation of Antibody Diversity in the Immune Response of BALB/c Mice to Influenza Virus Hemagglutinin. Proc. Natl. Acad. Sci. USA 1984. 81: 3180–3184.

David McKean, Konrad Huppi, Michael Bell, Louis Staudt, Walter Gerhard, and Martin Weigert
J Immunol 2008 180: 5765-5769. [PDF]  

BRIEF REVIEWS:

IL-10: The Master Regulator of Immunity to Infection

Kevin N. Couper, Daniel G. Blount, and Eleanor M. Riley
J Immunol 2008 180: 5771-5777. [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: Membrane Nanotubes In Vivo: A Feature of MHC Class II⁺ Cells in the Mouse Cornea

Holly R. Chinnery, Eric Pearlman, and Paul G. McMenamin
J Immunol 2008 180: 5779-5783. [Abstract] [Full Text] [PDF]  

Cutting Edge: Dendritic Cells Prime a High Avidity CTL Response Independent of the Level of Presented Antigen

Charles J. Kroger, Samuel Amoah, and Martha A. Alexander-Miller
J Immunol 2008 180: 5784-5788. [Abstract] [Full Text] [PDF]  

Cutting Edge: Enhanced IL-2 Signaling Can Convert Self-Specific T Cell Response from Tolerance to Autoimmunity

Jason Waithman, Thomas Gebhardt, Gayle M. Davey, William R. Heath, and Francis R. Carbone
J Immunol 2008 180: 5789-5793. [Abstract] [Full Text] [PDF]  

Cutting Edge: Foxp3-Mediated Induction of Pim 2 Allows Human T Regulatory Cells to Preferentially Expand in Rapamycin

Samik Basu, Tatiana Golovina, Tatiana Mikheeva, Carl H. June, and James L. Riley
J Immunol 2008 180: 5794-5798. [Abstract] [Full Text] [PDF]  

Cutting Edge: Overlapping Functions of TLR7 and TLR9 for Innate Defense against a Herpesvirus Infection

Nicolas Zucchini, Gilles Bessou, Stephanie Traub, Scott H. Robbins, Satoshi Uematsu, Shizuo Akira, Lena Alexopoulou, and Marc Dalod
J Immunol 2008 180: 5799-5803. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Lck-Dependent Tyrosine Phosphorylation of Diacylglycerol Kinase Regulates Its Membrane Association in T Cells

Ernesto Merino, Antonia Ávila-Flores, Yasuhito Shirai, Ignacio Moraga, Naoaki Saito, and Isabel Mérida
J Immunol 2008 180: 5805-5815. [Abstract] [Full Text] [PDF]  

Virus-Like Display of a Neo-Self Antigen Reverses B Cell Anergy in a B Cell Receptor Transgenic Mouse Model

Bryce Chackerian, Marisa R. Durfee, and John T. Schiller
J Immunol 2008 180: 5816-5825. [Abstract] [Full Text] [PDF]  

Danger Signaling through the Inflammasome Acts as a Master Switch between Tolerance and Sensitization

Hideki Watanabe, Samuel Gehrke, Emmanuel Contassot, Stéphanie Roques, Jürg Tschopp, Peter S. Friedmann, Lars E. French, and Olivier Gaide
J Immunol 2008 180: 5826-5832. [Abstract] [Full Text] [PDF]  

Conserved Mycobacterial Lipoglycoproteins Activate TLR2 but Also Require Glycosylation for MHC Class II-Restricted T Cell Activation

Peter A. Sieling, Preston J. Hill, Karen M. Dobos, Kerry Brookman, Andrew M. Kuhlman, Mario Fabri, Stephan R. Krutzik, Thomas H. Rea, Darragh G. Heaslip, John T. Belisle, and Robert L. Modlin
J Immunol 2008 180: 5833-5842. [Abstract] [Full Text] [PDF]  

Systemic Control of Plasmacytoid Dendritic Cells by CD8⁺ T Cells and Commensal Microbiota

Daisuke Fujiwara, Bo Wei, Laura L. Presley, Sarah Brewer, Michael McPherson, Michael A. Lewinski, James Borneman, and Jonathan Braun
J Immunol 2008 180: 5843-5852. [Abstract] [Full Text] [PDF]  

Pathogen Proliferation Governs the Magnitude but Compromises the Function of CD8 T Cells

Subash Sad, Renu Dudani, Komal Gurnani, Marsha Russell, Henk van Faassen, Brett Finlay, and Lakshmi Krishnan
J Immunol 2008 180: 5853-5861. [Abstract] [Full Text] [PDF]  

Differential Control of T Regulatory Cell Proliferation and Suppressive Activity by Mature Plasmacytoid versus Conventional Spleen Dendritic Cells

Asmahan Ouabed, Francois-Xavier Hubert, Dominique Chabannes, Laetitia Gautreau, Michèle Heslan, and Régis Josien
J Immunol 2008 180: 5862-5870. [Abstract] [Full Text] [PDF]  

Tumor-Induced Impairment of TCR Signaling Results in Compromised Functionality of Tumor-Infiltrating Regulatory T Cells

M. E. Christine Lutsiak, Yutaka Tagaya, Anthony J. Adams, Jeffrey Schlom, and Helen Sabzevari
J Immunol 2008 180: 5871-5881. [Abstract] [Full Text] [PDF]  

IFN- and IL-17 Production in Experimental Autoimmune Encephalomyelitis Depends on Local APC–T Cell Complement Production

Jinbo Liu, Feng Lin, Michael G. Strainic, Fengqi An, Robert H. Miller, Cengiz Z. Altuntas, Peter S. Heeger, Vincent K. Tuohy, and M. Edward Medof
J Immunol 2008 180: 5882-5889. [Abstract] [Full Text] [PDF]  

CD83 Expression in CD4⁺ T Cells Modulates Inflammation and Autoimmunity

Simone Reinwald, Carsten Wiethe, Astrid M. Westendorf, Minka Breloer, Michael Probst-Kepper, Bernhard Fleischer, Alexander Steinkasserer, Jan Buer, and Wiebke Hansen
J Immunol 2008 180: 5890-5897. [Abstract] [Full Text] [PDF]  

Deacetylase Activity Is Required for STAT5-Dependent GM-CSF Functional Activity in Macrophages and Differentiation to Dendritic Cells

Carlos Sebastián, Maria Serra, Andrée Yeramian, Neus Serrat, Jorge Lloberas, and Antonio Celada
J Immunol 2008 180: 5898-5906. [Abstract] [Full Text] [PDF]  

HIV-1-Specific T Cell Precursors with High Proliferative Capacity Correlate with Low Viremia and High CD4 Counts in Untreated Individuals

Sandra A. Calarota, Andrea Foli, Renato Maserati, Fausto Baldanti, Stefania Paolucci, Mary A. Young, Christos M. Tsoukas, Julianna Lisziewicz, and Franco Lori
J Immunol 2008 180: 5907-5915. [Abstract] [Full Text] [PDF]  

Regulatory T Cells Inhibit Dendritic Cells by Lymphocyte Activation Gene-3 Engagement of MHC Class II

Bitao Liang, Craig Workman, Janine Lee, Claude Chew, Benjamin M. Dale, Lucrezia Colonna, Marcella Flores, Nianyu Li, Edina Schweighoffer, Steven Greenberg, Victor Tybulewicz, Dario Vignali, and Raphael Clynes
J Immunol 2008 180: 5916-5926. [Abstract] [Full Text] [PDF]  

Disruption of Mutually Negative Regulatory Feedback Loop between Interferon-Inducible p202 Protein and the E2F Family of Transcription Factors in Lupus-Prone Mice

Ravichandran Panchanathan, Hong Xin, and Divaker Choubey
J Immunol 2008 180: 5927-5934. [Abstract] [Full Text] [PDF]  

IL-12 Signaling Drives CD8⁺ T Cell IFN- Production and Differentiation of KLRG1⁺ Effector Subpopulations during Toxoplasma gondii Infection

Douglas C. Wilson, Suzanne Matthews, and George S. Yap
J Immunol 2008 180: 5935-5945. [Abstract] [Full Text] [PDF]  

An Interaction between CD200 and Monoclonal Antibody Agonists to CD200R2 in Development of Dendritic Cells That Preferentially Induce Populations of CD4⁺CD25⁺ T Regulatory Cells

Reg Gorczynski, Ismat Khatri, Lydia Lee, and Ivo Boudakov
J Immunol 2008 180: 5946-5955. [Abstract] [Full Text] [PDF]  

Conversion of Tyrosine to the Inflammation-Associated Analog 3'-Nitrotyrosine at Either TCR- or MHC-Contact Positions Can Profoundly Affect Recognition of the MHC Class I-Restricted Epitope of Lymphocytic Choriomeningitis Virus Glycoprotein 33 by CD8 T Cells

Lani L. Hardy, Darin A. Wick, and John R. Webb
J Immunol 2008 180: 5956-5962. [Abstract] [Full Text] [PDF]  

Plasmacytoid Dendritic Cells Migrate in Afferent Skin Lymph

Florentia Pascale, Vanessa Contreras, Michel Bonneau, Alexandre Courbet, Stefan Chilmonczyk, Claudia Bevilacqua, Mathieu Eparaud, Violeta Niborski, Sabine Riffault, Anne-Marie Balazuc, Eliane Foulon, Laurence Guzylack-Piriou, Beatrice Riteau, Jayne Hope, Nicolas Bertho, Bernard Charley, and Isabelle Schwartz-Cornil
J Immunol 2008 180: 5963-5972. [Abstract] [Full Text] [PDF]  

Preferential Development of CD4 and CD8 T Regulatory Cells in RasGRP1-Deficient Mice

Xiaoxi Chen, John J. Priatel, Michael T. Chow, and Hung-Sia Teh
J Immunol 2008 180: 5973-5982. [Abstract] [Full Text] [PDF]  

SUMOylation Regulates the Transcriptional Activity of JunB in T Lymphocytes

Johan Garaude, Rosa Farrás, Guillaume Bossis, Seyma Charni, Marc Piechaczyk, Robert A. Hipskind, and Martin Villalba
J Immunol 2008 180: 5983-5990. [Abstract] [Full Text] [PDF]  

Prevention of Allograft Tolerance by Bacterial Infection with Listeria monocytogenes

Tongmin Wang, Luqiu Chen, Emily Ahmed, Lianli Ma, Dengping Yin, Ping Zhou, Jikun Shen, Honglin Xu, Chyung-Ru Wang, Maria-Luisa Alegre, and Anita S. Chong
J Immunol 2008 180: 5991-5999. [Abstract] [Full Text] [PDF]  

Fungal Proteases Induce Th2 Polarization through Limited Dendritic Cell Maturation and Reduced Production of IL-12

Salah-Eddine Lamhamedi-Cherradi, Rachel Elizabeth Martin, Tomoki Ito, Farrah Kheradmand, David Brian Corry, Yong-Jun Liu, and Matthew Moyle
J Immunol 2008 180: 6000-6009. [Abstract] [Full Text] [PDF]  

Inorganic Arsenic Activates Reduced NADPH Oxidase in Human Primary Macrophages through a Rho Kinase/p38 Kinase Pathway

Anthony Lemarie, Emilie Bourdonnay, Claudie Morzadec, Olivier Fardel, and Laurent Vernhet
J Immunol 2008 180: 6010-6017. [Abstract] [Full Text] [PDF]  

Reovirus Activates Human Dendritic Cells to Promote Innate Antitumor Immunity

Fiona Errington, Lynette Steele, Robin Prestwich, Kevin J. Harrington, Hardev S. Pandha, Laura Vidal, Johann de Bono, Peter Selby, Matt Coffey, Richard Vile, and Alan Melcher
J Immunol 2008 180: 6018-6026. [Abstract] [Full Text] [PDF]  

Phospholipase D1 Plays a Key Role in TNF- Signaling

Swaminathan Sethu, Grecia Mendez-Corao, and Alirio J. Melendez
J Immunol 2008 180: 6027-6034. [Abstract] [Full Text] [PDF]  

TLR6 Modulates First Trimester Trophoblast Responses to Peptidoglycan

Vikki M. Abrahams, Paulomi B. Aldo, Shaun P. Murphy, Irene Visintin, Kaori Koga, Gabriella Wilson, Roberto Romero, Surendra Sharma, and Gil Mor
J Immunol 2008 180: 6035-6043. [Abstract] [Full Text] [PDF]  

Protective Immunosurveillance and Therapeutic Antitumor Activity of T Cells Demonstrated in a Mouse Model of Prostate Cancer

Zhiyong Liu, Isam-Eldin A. Eltoum, Ben Guo, Benjamin H. Beck, Gretchen A. Cloud, and Richard D. Lopez
J Immunol 2008 180: 6044-6053. [Abstract] [Full Text] [PDF]  

Characterization of IL-10-Secreting T Cells Derived from Regulatory CD4⁺CD25⁺ Cells by the TIRC7 Surface Marker

Abdelilah Wakkach, Séverine Augier, Jean-Philippe Breittmayer, Claudine Blin-Wakkach, and Georges F. Carle
J Immunol 2008 180: 6054-6063. [Abstract] [Full Text] [PDF]  

Suppression of Normal and Malignant Kit Signaling by a Bispecific Antibody Linking Kit with CD300a

Ido Bachelet, Ariel Munitz, Beata Berent-Maoz, David Mankuta, and Francesca Levi-Schaffer
J Immunol 2008 180: 6064-6069. [Abstract] [Full Text] [PDF]  

Loss of STAT3 in CD4⁺ T Cells Prevents Development of Experimental Autoimmune Diseases

Xuebin Liu, Yun Sang Lee, Cheng-Rong Yu, and Charles E. Egwuagu
J Immunol 2008 180: 6070-6076. [Abstract] [Full Text] [PDF]  

Long-Term Control of Alloreactive B Cell Responses by the Suppression of T Cell Help

Yijin Li, Lianli Ma, Dengping Yin, JiKun Shen, and Anita S. Chong
J Immunol 2008 180: 6077-6084. [Abstract] [Full Text] [PDF]  

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Inhibits Proximal TCR Signaling by Targeting ZAP-70

Zhangguo Chen, Lanfen Chen, Shuo-Wang Qiao, Takashi Nagaishi, and Richard S. Blumberg
J Immunol 2008 180: 6085-6093. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Antigen Receptor Editing in Anti-DNA Transitional B Cells Deficient for Surface IgM

Kerstin Kiefer, Pamela B. Nakajima, Jennifer Oshinsky, Steven H. Seeholzer, Marko Radic, Gayle C. Bosma, and Melvin J. Bosma
J Immunol 2008 180: 6094-6106. [Abstract] [Full Text] [PDF]  

Functional Activity of MD-2 Polymorphic Variant Is Significantly Different in Soluble and TLR4-Bound Forms: Decreased Endotoxin Binding by G56R MD-2 and Its Rescue by TLR4 Ectodomain

Jozica Vasl, Polonca Prohinar, Theresa L. Gioannini, Jerrold P. Weiss, and Roman Jerala
J Immunol 2008 180: 6107-6115. [Abstract] [Full Text] [PDF]  

Single and Dual Amino Acid Substitutions in TCR CDRs Can Enhance Antigen-Specific T Cell Functions

Paul F. Robbins, Yong F. Li, Mona El-Gamil, Yangbing Zhao, Jennifer A. Wargo, Zhili Zheng, Hui Xu, Richard A. Morgan, Steven A. Feldman, Laura A. Johnson, Alan D. Bennett, Steven M. Dunn, Tara M. Mahon, Bent K. Jakobsen, and Steven A. Rosenberg
J Immunol 2008 180: 6116-6131. [Abstract] [Full Text] [PDF]  

Mannose-Binding Lectin (MBL)-Associated Serine Protease (MASP)-1 Contributes to Activation of the Lectin Complement Pathway

Minoru Takahashi, Daisuke Iwaki, Kazuko Kanno, Yumi Ishida, Jie Xiong, Misao Matsushita, Yuichi Endo, Shigeto Miura, Naoto Ishii, Kazuo Sugamura, and Teizo Fujita
J Immunol 2008 180: 6132-6138. [Abstract] [Full Text] [PDF]  

IMMUNOGENETICS:

Immunological and Genetic Evidence for a Crucial Role of IL-10 in Cutaneous Lesions in Humans Infected with Leishmania braziliensis

Adnene Salhi, Virmondes Rodrigues, Jr., Ferrucio Santoro, Helia Dessein, Audrey Romano, Lucio Roberto Castellano, Mathieu Sertorio, Sima Rafati, Christophe Chevillard, Aluisio Prata, Alexandre Alcaïs, Laurent Argiro, and Alain Dessein
J Immunol 2008 180: 6139-6148. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Lipoproteins Are Critical TLR2 Activating Toxins in Group B Streptococcal Sepsis

Philipp Henneke, Shaynoor Dramsi, Giuseppe Mancuso, Kamila Chraibi, Elisabeth Pellegrini, Christian Theilacker, Johannes Hübner, Sandra Santos-Sierra, Giuseppe Teti, Douglas T. Golenbock, Claire Poyart, and Patrick Trieu-Cuot
J Immunol 2008 180: 6149-6158. [Abstract] [Full Text] [PDF]  

A DNA Vaccine Prime Followed by a Liposome-Encapsulated Protein Boost Confers Enhanced Mucosal Immune Responses and Protection

Kejian Yang, Barbara J. Whalen, Rebecca S. Tirabassi, Liisa K. Selin, Tatyana S. Levchenko, Vladimir P. Torchilin, Edward H. Kislauskis, and Dennis L. Guberski
J Immunol 2008 180: 6159-6167. [Abstract] [Full Text] [PDF]  

Alternatively Activated Myeloid Cells Limit Pathogenicity Associated with African Trypanosomiasis through the IL-10 Inducible Gene Selenoprotein P

Tom Bosschaerts, Martin Guilliams, Wim Noel, Michel Hérin, Raymond F. Burk, Kristina E. Hill, Lea Brys, Geert Raes, Gholamreza Hassanzadeh Ghassabeh, Patrick De Baetselier, and Alain Beschin
J Immunol 2008 180: 6168-6175. [Abstract] [Full Text] [PDF]  

Neisseria gonorrhoeae-Induced Human Defensins 5 and 6 Increase HIV Infectivity: Role in Enhanced Transmission

Mary E. Klotman, Aprille Rapista, Natalia Teleshova, Amanda Micsenyi, Gary A. Jarvis, Wuyuan Lu, Edith Porter, and Theresa L. Chang
J Immunol 2008 180: 6176-6185. [Abstract] [Full Text] [PDF]  

Tick Saliva Inhibits Dendritic Cell Migration, Maturation, and Function while Promoting Development of Th2 Responses

Anna Skallová, Giandomenica Iezzi, Franziska Ampenberger, Manfred Kopf, and Jan Kopecky
J Immunol 2008 180: 6186-6192. [Abstract] [Full Text] [PDF]  

T Cell Response Mediated by Myeloid Cell-Derived IL-12 Is Responsible for Porphyromonas gingivalis-Induced Periodontitis in IL-10-Deficient Mice

Hajime Sasaki, Noriyuki Suzuki, Ralph Kent, Jr., Nobuyuki Kawashima, Junji Takeda, and Philip Stashenko
J Immunol 2008 180: 6193-6198. [Abstract] [Full Text] [PDF]  

Inhibition of Yin Yang 1-Dependent Repressor Activity of DR5 Transcription and Expression by the Novel Proteasome Inhibitor NPI-0052 Contributes to its TRAIL-Enhanced Apoptosis in Cancer Cells

Stavroula Baritaki, Eriko Suzuki, Kazuo Umezawa, Demetrios A. Spandidos, James Berenson, Tracy R. Daniels, Manuel L. Penichet, Ali R. Jazirehi, Michael Palladino, and Benjamin Bonavida
J Immunol 2008 180: 6199-6210. [Abstract] [Full Text] [PDF]  

Leukotriene B₄ Induces Release of Antimicrobial Peptides in Lungs of Virally Infected Mice

Éric Gaudreault and Jean Gosselin
J Immunol 2008 180: 6211-6221. [Abstract] [Full Text] [PDF]  

Bactericidal Action of a Complement-Independent Antibody against Relapsing Fever Borrelia Resides in Its Variable Region

Timothy J. LaRocca, Laura I. Katona, David G. Thanassi, and Jorge L. Benach
J Immunol 2008 180: 6222-6228. [Abstract] [Full Text] [PDF]  

Plasmacytoid Dendritic Cells Are Activated by Toxoplasma gondii to Present Antigen and Produce Cytokines

Marion Pepper, Florence Dzierszinski, Emma Wilson, Elia Tait, Qun Fang, Felix Yarovinsky, Terri M. Laufer, David Roos, and Christopher A. Hunter
J Immunol 2008 180: 6229-6236. [Abstract] [Full Text] [PDF]  

Chlamydia muridarum Evades Growth Restriction by the IFN--Inducible Host Resistance Factor Irgb10

Jörn Coers, Isaac Bernstein-Hanley, David Grotsky, Iana Parvanova, Jonathan C. Howard, Gregory A. Taylor, William F. Dietrich, and Michael N. Starnbach
J Immunol 2008 180: 6237-6245. [Abstract] [Full Text] [PDF]  

Neutrophil-Toxin Interactions Promote Antigen Delivery and Mucosal Clearance of Streptococcus pneumoniae

Kathryn A. Matthias, Aoife M. Roche, Alistair J. Standish, Mikhail Shchepetov, and Jeffrey N. Weiser
J Immunol 2008 180: 6246-6254. [Abstract] [Full Text] [PDF]  

Pattern Recognition Molecule Mindin Promotes Intranasal Clearance of Influenza Viruses

Wei Jia, Hong Li, and You-Wen He
J Immunol 2008 180: 6255-6261. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Identification of Pendrin as a Common Mediator for Mucus Production in Bronchial Asthma and Chronic Obstructive Pulmonary Disease

Isao Nakao, Sachiko Kanaji, Shoichiro Ohta, Hidetomo Matsushita, Kazuhiko Arima, Noriko Yuyama, Mutsuo Yamaya, Katsutoshi Nakayama, Hiroshi Kubo, Mika Watanabe, Hironori Sagara, Kumiya Sugiyama, Hiroyuki Tanaka, Shuji Toda, Hiroaki Hayashi, Hiromasa Inoue, Tomoaki Hoshino, Aya Shiraki, Makoto Inoue, Koichi Suzuki, Hisamichi Aizawa, Satoshi Okinami, Hiroichi Nagai, Mamoru Hasegawa, Takeshi Fukuda, Eric D. Green, and Kenji Izuhara
J Immunol 2008 180: 6262-6269. [Abstract] [Full Text] [PDF]  

Unique Expression of Suppressor of Cytokine Signaling 3 Is Essential for Classical Macrophage Activation in Rodents In Vitro and In Vivo

Yu Liu, Keith N. Stewart, Eileen Bishop, Carylyn J. Marek, David C. Kluth, Andrew J. Rees, and Heather M. Wilson
J Immunol 2008 180: 6270-6278. [Abstract] [Full Text] [PDF]  

Requirement for Vav Proteins in Post-Recruitment Neutrophil Cytotoxicity in IgG but Not Complement C3-Dependent Injury

Ahmad Utomo, Junichi Hirahashi, Divya Mekala, Kenichi Asano, Michael Glogauer, Xavier Cullere, and Tanya N. Mayadas
J Immunol 2008 180: 6279-6287. [Abstract] [Full Text] [PDF]  

CD73-Generated Adenosine Restricts Lymphocyte Migration into Draining Lymph Nodes

Masahide Takedachi, Dongfeng Qu, Yukihiko Ebisuno, Hiroyuki Oohara, Michelle L. Joachims, Stephanie T. McGee, Emiko Maeda, Rodger P. McEver, Toshiyuki Tanaka, Masayuki Miyasaka, Shinya Murakami, Thomas Krahn, Michael R. Blackburn, and Linda F. Thompson
J Immunol 2008 180: 6288-6296. [Abstract] [Full Text] [PDF]  

IL-10 and Natural Regulatory T Cells: Two Independent Anti-Inflammatory Mechanisms in Herpes Simplex Virus-Induced Ocular Immunopathology

Pranita P. Sarangi, Sharvan Sehrawat, Susmit Suvas, and Barry T. Rouse
J Immunol 2008 180: 6297-6306. [Abstract] [Full Text] [PDF]  

Generation of Anaphylatoxins by Human β-Tryptase from C3, C4, and C5

Yoshihiro Fukuoka, Han-Zhang Xia, Laura B. Sanchez-Muñoz, Anthony L. Dellinger, Luis Escribano, and Lawrence B. Schwartz
J Immunol 2008 180: 6307-6316. [Abstract] [Full Text] [PDF]  

TLR2-Mediated Activation of Neutrophils in Response to German Cockroach Frass

Kristen Page, Kristin M. Lierl, Valerie S. Hughes, Ping Zhou, John R. Ledford, and Marsha Wills-Karp
J Immunol 2008 180: 6317-6324. [Abstract] [Full Text] [PDF]  

IL-27 Activates Human Monocytes via STAT1 and Suppresses IL-10 Production but the Inflammatory Functions of IL-27 Are Abrogated by TLRs and p38

George D. Kalliolias and Lionel B. Ivashkiv
J Immunol 2008 180: 6325-6333. [Abstract] [Full Text] [PDF]  

NK but Not CD1-Restricted NKT Cells Facilitate Systemic Inflammation during Polymicrobial Intra-Abdominal Sepsis

Anthony O. Etogo, Jesus Nunez, Cheng Y. Lin, Tracy E. Toliver-Kinsky, and Edward R. Sherwood
J Immunol 2008 180: 6334-6345. [Abstract] [Full Text] [PDF]  

Cytokine Secretion Depends on Gal(1,3)Gal Expression in a Pig-to-Human Whole Blood Model

Marit Sæthre, Mårten K. J. Schneider, John D. Lambris, Paola Magotti, Guttorm Haraldsen, Jörg D. Seebach, and Tom E. Mollnes
J Immunol 2008 180: 6346-6353. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Use of Allograft Biopsies to Assess Thymopoiesis after Thymus Transplantation

M. Louise Markert, Jie Li, Blythe H. Devlin, Jeffrey C. Hoehner, Henry E. Rice, Michael A. Skinner, Yi-Ju Li, and Laura P. Hale
J Immunol 2008 180: 6354-6364. [Abstract] [Full Text] [PDF]  

An Inducible Caspase 9 Safety Switch Can Halt Cell Therapy-Induced Autoimmune Disease

Moniek A. de Witte, Annelies Jorritsma, Erwin Swart, Karin C. Straathof, Karin de Punder, John B. A. G. Haanen, Cliona M. Rooney, and Ton N. M. Schumacher
J Immunol 2008 180: 6365-6373. [Abstract] [Full Text] [PDF]  

Humoral Immune Responses against the Immature Laminin Receptor Protein Show Prognostic Significance in Patients with Chronic Lymphocytic Leukemia

Birte Friedrichs, Sandra Siegel, Marita Kloess, Adel Barsoum, Joseph Coggin, Jr., James Rohrer, Ilja Jakob, Markus Tiemann, Klaus Heidorn, Christoph Schulte, Dieter Kabelitz, Jörg Steinmann, Norbert Schmitz, and Matthias Zeis
J Immunol 2008 180: 6374-6384. [Abstract] [Full Text] [PDF]  

A Novel Non-Synonymous Polymorphism (p.Arg240His) in C4b-Binding Protein Is Associated with Atypical Hemolytic Uremic Syndrome and Leads to Impaired Alternative Pathway Cofactor Activity

Anna M. Blom, Frida Bergström, Matthew Edey, Martha Diaz-Torres, David Kavanagh, Anne Lampe, Judith A. Goodship, Lisa Strain, Nadeem Moghal, Mary McHugh, Carol Inward, Charles Tomson, Véronique Frémeaux-Bacchi, Bruno O. Villoutreix, and Timothy H. J. Goodship
J Immunol 2008 180: 6385-6391. [Abstract] [Full Text] [PDF]  

Blocking NK Cell Inhibitory Self-Recognition Promotes Antibody-Dependent Cellular Cytotoxicity in a Model of Anti-Lymphoma Therapy

Liat Binyamin, R. Katherine Alpaugh, Tracey L. Hughes, Charles T. Lutz, Kerry S. Campbell, and Louis M. Weiner
J Immunol 2008 180: 6392-6401. [Abstract] [Full Text] [PDF]  

Correlation of Blood T Cell and Antibody Reactivity to Myelin Proteins with HLA Type and Lesion Localization in Multiple Sclerosis

Judith M. Greer, Peter A. Csurhes, Diane M. Muller, and Michael P. Pender
J Immunol 2008 180: 6402-6410. [Abstract] [Full Text] [PDF]  

Natural Naive CD4⁺CD25⁺CD127^low Regulatory T Cell (Treg) Development and Function Are Disturbed in Multiple Sclerosis Patients: Recovery of Memory Treg Homeostasis during Disease Progression

Koen Venken, Niels Hellings, Tom Broekmans, Karen Hensen, Jean-Luc Rummens, and Piet Stinissen
J Immunol 2008 180: 6411-6420. [Abstract] [Full Text] [PDF]  

Decreased Expression of the Fractalkine Receptor CX3CR1 on Circulating Monocytes as New Feature of Sepsis-Induced Immunosuppression

Alexandre Pachot, Marie-Angélique Cazalis, Fabienne Venet, Fanny Turrel, Caroline Faudot, Nicolas Voirin, Jennifer Diasparra, Naïck Bourgoin, Françoise Poitevin, Bruno Mougin, Alain Lepape, and Guillaume Monneret
J Immunol 2008 180: 6421-6429. [Abstract] [Full Text] [PDF]  

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