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On the cover: Coxsackie virus B3-induced cardiac fibrosis develops in the absence of PKC-θ. Depicted is Sirius-red staining of heart tissue from a wild-type mouse 35 days after infection with CVB3. Marsland, B. J., C. Nembrini, K. Grün, R. Reissmann, M. Kurrer, C. Leipner, and M. Kopf. 2007. TLR ligands act directly upon T cells to restore proliferation in the absence of protein kinase C-θ signaling and promote autoimmune myocarditis. J. Immunol. 178: 3466–3473.
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