EDITORIALS:

From Whence We Come (Happy Birthday to Us)

Robert R. Rich
J Immunol 2006 176: 2031-2032. [Full Text] [PDF]  

90th Anniversary Article: Studies in Anaphylaxis. XIV. On the Relation between Precipitin and Sensitizin. J. Immunol. 1916. 1: 1–18.

Richard Weil
J Immunol 2006 176: 2033-2050. [PDF]  

IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2006 176: 2051-2052. [Full Text] [PDF]  

BRIEF REVIEWS:

Experimental Models to Study Development and Function of the Human Immune System In Vivo

Nicolas Legrand, Kees Weijer, and Hergen Spits
J Immunol 2006 176: 2053-2058. [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: An Alternative Pathway of CD4⁺ T Cell Differentiation Is Induced Following Activation in the Absence of -Chain-Dependent Cytokine Signals

Shane R. Mayack and Leslie J. Berg
J Immunol 2006 176: 2059-2063. [Abstract] [Full Text] [PDF]  

Cutting Edge: Influence of the TCR V Domain on the Selection of Semi-Invariant NKT Cells by Endogenous Ligands

Jens Schümann, Marcin P. Mycko, Paolo Dellabona, Giulia Casorati, and H. Robson MacDonald
J Immunol 2006 176: 2064-2068. [Abstract] [Full Text] [PDF]  

Cutting Edge: Novel Human Dendritic Cell- and Monocyte-Attracting Chemokine-Like Protein Identified by Fold Recognition Methods

M. Teresa Pisabarro, Beatrice Leung, Mandy Kwong, Racquel Corpuz, Gretchen D. Frantz, Nancy Chiang, Richard Vandlen, Lauri J. Diehl, Nicholas Skelton, Hok Seon Kim, Dan Eaton, and Kerstin N. Schmidt
J Immunol 2006 176: 2069-2073. [Abstract] [Full Text] [PDF]  

Cutting Edge: Enhancement of Antibody Responses Through Direct Stimulation of B and T Cells by Type I IFN

Agnes Le Bon, Clare Thompson, Elisabeth Kamphuis, Vanessa Durand, Cornelia Rossmann, Ulrich Kalinke, and David F. Tough
J Immunol 2006 176: 2074-2078. [Abstract] [Full Text] [PDF]  

Cutting Edge: Gut Microenvironment Promotes Differentiation of a Unique Memory CD8 T Cell Population

David Masopust, Vaiva Vezys, E. John Wherry, Daniel L. Barber, and Rafi Ahmed
J Immunol 2006 176: 2079-2083. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

CD11b⁺/Gr-1⁺ Myeloid Suppressor Cells Cause T Cell Dysfunction after Traumatic Stress

Valeriya P. Makarenkova, Vishal Bansal, Benjamin M. Matta, Lori Ann Perez, and Juan B. Ochoa
J Immunol 2006 176: 2085-2094. [Abstract] [Full Text] [PDF]  

Accelerated Macrophage Apoptosis Induces Autoantibody Formation and Organ Damage in Systemic Lupus Erythematosus

Michael F. Denny, Parthapratim Chandaroy, Paul D. Killen, Roberto Caricchio, Emily E. Lewis, Bruce C. Richardson, Kyung-Dall Lee, Jerrie Gavalchin, and Mariana J. Kaplan
J Immunol 2006 176: 2095-2104. [Abstract] [Full Text] [PDF]  

LFA-1-Dependent HuR Nuclear Export and Cytokine mRNA Stabilization in T Cell Activation

Jin Gene Wang, Mark Collinge, Vinod Ramgolam, Oran Ayalon, Xinhao Cynthia Fan, Ruggero Pardi, and Jeffrey R. Bender
J Immunol 2006 176: 2105-2113. [Abstract] [Full Text] [PDF]  

IL-3-Mediated TNF Production Is Necessary for Mast Cell Development

Harry V. Wright, Daniel Bailey, Mohit Kashyap, Christopher L. Kepley, Marina S. Drutskaya, Sergei A. Nedospasov, and John J. Ryan
J Immunol 2006 176: 2114-2121. [Abstract] [Full Text] [PDF]  

Role of MHC Class II on Memory B Cells in Post-Germinal Center B Cell Homeostasis and Memory Response

Michiko Shimoda, Tao Li, Jeanene P. S. Pihkala, and Pandelakis A. Koni
J Immunol 2006 176: 2122-2133. [Abstract] [Full Text] [PDF]  

Hyperthermia Enhances CTL Cross-Priming

Hongzhen Shi, Tinghua Cao, John E. Connolly, Laurence Monnet, Lynda Bennett, Sylvie Chapel, Claude Bagnis, Patrice Mannoni, Jean Davoust, A. Karolina Palucka, and Jacques Banchereau
J Immunol 2006 176: 2134-2141. [Abstract] [Full Text] [PDF]  

B Cell Tolerance Checkpoints That Restrict Pathways of Antigen-Driven Differentiation

Jacqueline William, Chad Euler, Nicole Primarolo, and Mark J. Shlomchik
J Immunol 2006 176: 2142-2151. [Abstract] [Full Text] [PDF]  

P2X₇ Receptors Regulate NKT Cells in Autoimmune Hepatitis

Hiroki Kawamura, Fred Aswad, Masahiro Minagawa, Sugantha Govindarajan, and Gunther Dennert
J Immunol 2006 176: 2152-2160. [Abstract] [Full Text] [PDF]  

A Major Lung CD103 (_E)-₇ Integrin-Positive Epithelial Dendritic Cell Population Expressing Langerin and Tight Junction Proteins

Sun-Sang J. Sung, Shu Man Fu, C. Edward Rose, Jr., Felicia Gaskin, Shyr-Te Ju, and Steven R. Beaty
J Immunol 2006 176: 2161-2172. [Abstract] [Full Text] [PDF]  

Distinct Mechanisms Control Human Naive and Antigen-Experienced CD8⁺ T Lymphocyte Proliferation

Marco Migliaccio, Pedro Miguel Sousa Alves, Pedro Romero, and Nathalie Rufer
J Immunol 2006 176: 2173-2182. [Abstract] [Full Text] [PDF]  

NF-B-Dependent Regulation of the Timing of Activation-Induced Cell Death of T Lymphocytes

Akanksha Mittal, Salvatore Papa, Guido Franzoso, and Ranjan Sen
J Immunol 2006 176: 2183-2189. [Abstract] [Full Text] [PDF]  

CD8 T Cells Specific for a Donor-Derived, Self-Restricted Transplant Antigen Are Nonpathogenic Bystanders after Vascularized Heart Transplantation in Mice

Anna Valujskikh, Qiwei Zhang, and Peter S. Heeger
J Immunol 2006 176: 2190-2196. [Abstract] [Full Text] [PDF]  

Expression and Regulation of the Orphan Receptor RDC1 and Its Putative Ligand in Human Dendritic and B Cells

Simona Infantino, Barbara Moepps, and Marcus Thelen
J Immunol 2006 176: 2197-2207. [Abstract] [Full Text] [PDF]  

Differential Role for Cyclic AMP Response Element Binding Protein-1 in Multiple Stages of B Cell Development, Differentiation, and Survival

Hui-Chen Chen, John C. Byrd, and Natarajan Muthusamy
J Immunol 2006 176: 2208-2218. [Abstract] [Full Text] [PDF]  

The JNK Are Important for Development and Survival of Macrophages

S. Roy Himes, David P. Sester, Timothy Ravasi, Stephen L. Cronau, Tedjo Sasmono, and David A. Hume
J Immunol 2006 176: 2219-2228. [Abstract] [Full Text] [PDF]  

Developmental Alterations in Thymocyte Sensitivity Are Actively Regulated by MHC Class II Expression in the Thymic Medulla

Steven C. Eck, Peimin Zhu, Marion Pepper, Steven J. Bensinger, Bruce D. Freedman, and Terri M. Laufer
J Immunol 2006 176: 2229-2237. [Abstract] [Full Text] [PDF]  

Mast Cells Enhance T Cell Activation: Importance of Mast Cell Costimulatory Molecules and Secreted TNF

Susumu Nakae, Hajime Suto, Motoyasu Iikura, Maki Kakurai, Jonathon D. Sedgwick, Mindy Tsai, and Stephen J. Galli
J Immunol 2006 176: 2238-2248. [Abstract] [Full Text] [PDF]  

Re-evaluating the Generation of a "Proteasome-Independent" MHC Class I-Restricted CD8 T Cell Epitope

E. John Wherry, Tatiana N. Golovina, Susan E. Morrison, Gomathinayagam Sinnathamby, Michael J. McElhaugh, David C. Shockey, and Laurence C. Eisenlohr
J Immunol 2006 176: 2249-2261. [Abstract] [Full Text] [PDF]  

Temporal and Dose-Dependent Relationships between In Vivo B Cell Receptor-Targeted Proliferation and Deletion-Induced by a Microbial B Cell Toxin

Carl S. Goodyear, Fujimi Sugiyama, and Gregg J. Silverman
J Immunol 2006 176: 2262-2271. [Abstract] [Full Text] [PDF]  

Human Mast Cells Undergo TRAIL-Induced Apoptosis

Beata Berent-Maoz, Adrian M. Piliponsky, Isabelle Daigle, Hans-Uwe Simon, and Francesca Levi-Schaffer
J Immunol 2006 176: 2272-2278. [Abstract] [Full Text] [PDF]  

Adaptive Tolerance and Clonal Anergy Are Distinct Biochemical States

Lynda Chiodetti, Seeyoung Choi, Daniel L. Barber, and Ronald H. Schwartz
J Immunol 2006 176: 2279-2291. [Abstract] [Full Text] [PDF]  

Antigen Exposure during Enhanced CTLA-4 Expression Promotes Allograft Tolerance In Vivo

Paolo R. O. Salvalaggio, Geoffrey Camirand, Charlotte E. Ariyan, Songyan Deng, Linda Rogozinski, Giacomo P. Basadonna, and David M. Rothstein
J Immunol 2006 176: 2292-2298. [Abstract] [Full Text] [PDF]  

Thymocyte Negative Selection Is Mediated by Protein Kinase C- and Ca²⁺-Dependent Transcriptional Induction of Bim

Kirsten Canté-Barrett, Elena M. Gallo, Monte M. Winslow, and Gerald R. Crabtree
J Immunol 2006 176: 2299-2306. [Abstract] [Full Text] [PDF]  

CD4-Dependent Potentiation of a High Molecular Weight-Melanoma-Associated Antigen-Specific CTL Response Elicited in HLA-A2/K^b Transgenic Mice

Liaomin Peng, Eric Ko, Wei Luo, Xinhui Wang, Protul A. Shrikant, and Soldano Ferrone
J Immunol 2006 176: 2307-2315. [Abstract] [Full Text] [PDF]  

Effector and Memory CD8⁺ T Cells Can Be Generated in Response to Alloantigen Independently of CD4⁺ T Cell Help

Nick D. Jones, Manuela Carvalho-Gaspar, Shiqiao Luo, Matthew O. Brook, Laurent Martin, and Kathryn J. Wood
J Immunol 2006 176: 2316-2323. [Abstract] [Full Text] [PDF]  

Frequency of Natural Regulatory CD4⁺CD25⁺ T Lymphocytes Determines the Outcome of Tolerance across Fully Mismatched MHC Barrier through Linked Recognition of Self and Allogeneic Stimuli

Rita Fucs, Joszilene T. Jesus, Paulo H. N. Souza Junior, Larissa Franco, Mauricio Verícimo, Maria Bellio, and Alberto Nobrega
J Immunol 2006 176: 2324-2329. [Abstract] [Full Text] [PDF]  

Ex Vivo Characterization of Allo-MHC-Restricted T Cells Specific for a Single MHC-Peptide Complex

Mikaël J. Pittet, Asma Gati, Frederic-Anne Le Gal, Gilles Bioley, Philippe Guillaume, Magda de Smedt, Jean Plum, Daniel E. Speiser, Jean-Charles Cerottini, Pierre-Yves Dietrich, Pedro Romero, and Alfred Zippelius
J Immunol 2006 176: 2330-2336. [Abstract] [Full Text] [PDF]  

Chemokine Receptor CXCR3 Desensitization by IL-16/CD4 Signaling Is Dependent on CCR5 and Intact Membrane Cholesterol

Shilpa Rahangdale, Roger Morgan, Claudia Heijens, Thomas C. Ryan, Hisato Yamasaki, Elizabeth Bentley, Elizabeth Sullivan, David M. Center, and William W. Cruikshank
J Immunol 2006 176: 2337-2345. [Abstract] [Full Text] [PDF]  

CCL5 Modulates Pneumococcal Immunity and Carriage

Ravichandran Palaniappan, Shailesh Singh, Udai P. Singh, Rajesh Singh, Edwin W. Ades, David E. Briles, Susan K. Hollingshead, Walter Royal, III, Jacquelyn S. Sampson, Jonathan K. Stiles, Dennis D. Taub, and James W. Lillard, Jr.
J Immunol 2006 176: 2346-2356. [Abstract] [Full Text] [PDF]  

Langerhans-Type Dendritic Cells Genetically Modified to Express Full-Length Antigen Optimally Stimulate CTLs in a CD4-Dependent Manner

Jianda Yuan, Jean-Baptiste Latouche, Joanna Hodges, Alan N. Houghton, Glenn Heller, Michel Sadelain, Isabelle Riviere, and James W. Young
J Immunol 2006 176: 2357-2365. [Abstract] [Full Text] [PDF]  

A Polymeric Bacterial Protein Activates Dendritic Cells via TLR4

Paula M. Berguer, Juliana Mundiñano, Isabel Piazzon, and Fernando A. Goldbaum
J Immunol 2006 176: 2366-2372. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Meningococcal Porin PorB Binds to TLR2 and Requires TLR1 for Signaling

Paola Massari, Alberto Visintin, Jay Gunawardana, Kristen A. Halmen, Carol A. King, Douglas T. Golenbock, and Lee M. Wetzler
J Immunol 2006 176: 2373-2380. [Abstract] [Full Text] [PDF]  

Position-Dependent Repression and Promotion of DQB1 Intron 3 Splicing by GGGG Motifs

Jana Královicová and Igor Vorechovsky
J Immunol 2006 176: 2381-2388. [Abstract] [Full Text] [PDF] Data Supplement  

B Cell-Specific Deficiency for Smad2 In Vivo Leads to Defects in TGF--Directed IgA Switching and Changes in B Cell Fate

Jörg Klein, Wenjun Ju, Jörg Heyer, Britta Wittek, Torsten Haneke, Petra Knaus, Raju Kucherlapati, Erwin P. Böttinger, Lars Nitschke, and Burkhard Kneitz
J Immunol 2006 176: 2389-2396. [Abstract] [Full Text] [PDF]  

CD161 (Human NKR-P1A) Signaling in NK Cells Involves the Activation of Acid Sphingomyelinase

David Pozo, Mar Valés-Gómez, Nasim Mavaddat, Sharon C. Williamson, Susan E. Chisholm, and Hugh Reyburn
J Immunol 2006 176: 2397-2406. [Abstract] [Full Text] [PDF]  

Involvement of Protein Kinase C in the Negative Regulation of Akt Activation Stimulated by Granulocyte Colony-Stimulating Factor

Hong Liu, Yaling Qiu, Lei Xiao, and Fan Dong
J Immunol 2006 176: 2407-2413. [Abstract] [Full Text] [PDF]  

Endotoxin-Induced Down-Regulation of Elk-3 Facilitates Heme Oxygenase-1 Induction in Macrophages

Su Wol Chung, Yen-Hsu Chen, Shaw-Fang Yet, Matthew D. Layne, and Mark A. Perrella
J Immunol 2006 176: 2414-2420. [Abstract] [Full Text] [PDF]  

Scaffolding Adapter Grb2-Associated Binder 2 Requires Syk to Transmit Signals from FcRI

Min Yu, Cliff A. Lowell, Benjamin G. Neel, and Haihua Gu
J Immunol 2006 176: 2421-2429. [Abstract] [Full Text] [PDF]  

Functional Hierarchy of the N-Terminal Tyrosines of SLP-76

Martha S. Jordan, Jeffrey Sadler, Jessica E. Austin, Lisa D. Finkelstein, Andrew L. Singer, Pamela L. Schwartzberg, and Gary A. Koretzky
J Immunol 2006 176: 2430-2438. [Abstract] [Full Text] [PDF]  

Regulation of IgH Gene Assembly: Role of the Intronic Enhancer and 5'D_Q52 Region in Targeting D_HJ_H Recombination

Roshi Afshar, Steven Pierce, Daniel J. Bolland, Anne Corcoran, and Eugene M. Oltz
J Immunol 2006 176: 2439-2447. [Abstract] [Full Text] [PDF]  

IMMUNOGENETICS:

The Molecular Basis for Gal(1,3)Gal Expression in Animals with a Deletion of the 1,3Galactosyltransferase Gene

Julie Milland, Dale Christiansen, Brooke D. Lazarus, Simon G. Taylor, Pei Xiang Xing, and Mauro S. Sandrin
J Immunol 2006 176: 2448-2454. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Modulation of the TLR-Mediated Inflammatory Response by the Endogenous Human Host Defense Peptide LL-37

Neeloffer Mookherjee, Kelly L. Brown, Dawn M. E. Bowdish, Silvana Doria, Reza Falsafi, Karsten Hokamp, Fiona M. Roche, Ruixia Mu, Gregory H. Doho, Jelena Pistolic, Jon-Paul Powers, Jenny Bryan, Fiona S. L. Brinkman, and Robert E. W. Hancock
J Immunol 2006 176: 2455-2464. [Abstract] [Full Text] [PDF]  

Transepithelial Pathogen Uptake into the Small Intestinal Lamina Propria

Alexandra Vallon-Eberhard, Limor Landsman, Nir Yogev, Bernard Verrier, and Steffen Jung
J Immunol 2006 176: 2465-2469. [Abstract] [Full Text] [PDF]  

Cytolytic CD8⁺ T Cells Directed against a Cryptic Epitope Derived from a Retroviral Alternative Reading Frame Confer Disease Protection

On Ho and William R. Green
J Immunol 2006 176: 2470-2475. [Abstract] [Full Text] [PDF]  

Activation of Invariant NKT Cells by the Helminth Parasite Schistosoma mansoni

Thierry Mallevaey, Jean Pierre Zanetta, Christelle Faveeuw, Josette Fontaine, Emmanuel Maes, Frances Platt, Monique Capron, Maria Leite- de-Moraes, and François Trottein
J Immunol 2006 176: 2476-2485. [Abstract] [Full Text] [PDF]  

OX40 Ligation of CD4⁺ T Cells Enhances Virus-Specific CD8⁺ T Cell Memory Responses Independently of IL-2 and CD4⁺ T Regulatory Cell Inhibition

Qigui Yu, Feng Yun Yue, Xiao X. Gu, Herbert Schwartz, Colin M. Kovacs, and Mario A. Ostrowski
J Immunol 2006 176: 2486-2495. [Abstract] [Full Text] [PDF]  

Impaired Protection against Mycobacterium bovis Bacillus Calmette-Guérin Infection in IL-15-Deficient Mice

Kimika Saito, Toshiki Yajima, Shino Kumabe, Takehiko Doi, Hisakata Yamada, Subash Sad, Hao Shen, and Yasunobu Yoshikai
J Immunol 2006 176: 2496-2504. [Abstract] [Full Text] [PDF]  

Induction of Enhanced Immunity to Intestinal Nematodes Using IL-9-Producing Dendritic Cells

Melanie D. Leech and Richard K. Grencis
J Immunol 2006 176: 2505-2511. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Gliadin Stimulation of Murine Macrophage Inflammatory Gene Expression and Intestinal Permeability Are MyD88-Dependent: Role of the Innate Immune Response in Celiac Disease

Karen E. Thomas, Anna Sapone, Alessio Fasano, and Stefanie N. Vogel
J Immunol 2006 176: 2512-2521. [Abstract] [Full Text] [PDF]  

Proinflammatory Cytokine Production in Liver Regeneration Is Myd88-Dependent, but Independent of Cd14, Tlr2, and Tlr4

Jean S. Campbell, Kimberly J. Riehle, John T. Brooling, Renay L. Bauer, Claudia Mitchell, and Nelson Fausto
J Immunol 2006 176: 2522-2528. [Abstract] [Full Text] [PDF]  

Priming of Glomerular Mesangial Cells by Activated Macrophages Causes Blunted Responses to Proinflammatory Stimuli

Kunihiro Hayakawa, Yiman Meng, Nobuhiko Hiramatsu, Ayumi Kasai, Kozue Yamauchi, Jian Yao, and Masanori Kitamura
J Immunol 2006 176: 2529-2537. [Abstract] [Full Text] [PDF]  

Neutrophils Regulate Airway Responses in a Model of Fungal Allergic Airways Disease

Stacy J. Park, Maria T. Wiekowski, Sergio A. Lira, and Borna Mehrad
J Immunol 2006 176: 2538-2545. [Abstract] [Full Text] [PDF]  

Impaired GATA3-Dependent Chromatin Remodeling and Th2 Cell Differentiation Leading to Attenuated Allergic Airway Inflammation in Aging Mice

Akihiro Hasegawa, Takako Miki, Hiroyuki Hosokawa, Mohammad B. Hossain, Chiori Shimizu, Kahoko Hashimoto, Motoko Y. Kimura, Masakatsu Yamashita, and Toshinori Nakayama
J Immunol 2006 176: 2546-2554. [Abstract] [Full Text] [PDF]  

Involvement of Group VIA Calcium-Independent Phospholipase A₂ in Macrophage Engulfment of Hydrogen Peroxide-Treated U937 Cells

Rebeca Pérez, María A. Balboa, and Jesús Balsinde
J Immunol 2006 176: 2555-2561. [Abstract] [Full Text] [PDF]  

Deletion of CCR1 Attenuates Pathophysiologic Responses during Respiratory Syncytial Virus Infection

Allison L. Miller, Craig Gerard, Matthew Schaller, Achim D. Gruber, Allison A. Humbles, and Nicholas W. Lukacs
J Immunol 2006 176: 2562-2567. [Abstract] [Full Text] [PDF]  

Inhalation Tolerance Is Induced Selectively in Thoracic Lymph Nodes but Executed Pervasively at Distant Mucosal and Nonmucosal Tissues

David Alvarez, Filip K. Swirski, Teng-Chih Yang, Ramzi Fattouh, Ken Croitoru, Jonathan L. Bramson, Martin R. Stämpfli, and Manel Jordana
J Immunol 2006 176: 2568-2580. [Abstract] [Full Text] [PDF]  

Epithelial CXCR3-B Regulates Chemokines Bioavailability in Normal, but Not in Sjögren’s Syndrome, Salivary Glands

Paolo Sfriso, Francesca Oliviero, Fiorella Calabrese, Marta Miorin, Monica Facco, Antonella Contri, Anna Cabrelle, Ilenia Baesso, Franco Cozzi, Marilisa Andretta, Marco Antonio Cassatella, Ugo Fiocco, Silvano Todesco, Yrjö T. Konttinen, Leonardo Punzi, and Carlo Agostini
J Immunol 2006 176: 2581-2589. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Ceramide-Dependent Regulation of Human Epidermal Keratinocyte CD1d Expression during Terminal Differentiation

Rita Fishelevich, Alla Malanina, Irina Luzina, Sergei Atamas, Miriam J. Smyth, Steven A. Porcelli, and Anthony A. Gaspari
J Immunol 2006 176: 2590-2599. [Abstract] [Full Text] [PDF]  

The Shaving Reaction: Rituximab/CD20 Complexes Are Removed from Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia Cells by THP-1 Monocytes

Paul V. Beum, Adam D. Kennedy, Michael E. Williams, Margaret A. Lindorfer, and Ronald P. Taylor
J Immunol 2006 176: 2600-2609. [Abstract] [Full Text] [PDF]  

Human NK Cells Positively Regulate T Cells in Response to Mycobacterium tuberculosis

Ruijun Zhang, Xiaodong Zheng, Baiqing Li, Haiming Wei, and Zhigang Tian
J Immunol 2006 176: 2610-2616. [Abstract] [Full Text] [PDF]  

TNF- Blockade Down-Regulates the CD40/CD40L Pathway in the Mucosal Microcirculation: A Novel Anti-Inflammatory Mechanism of Infliximab in Crohn’s Disease

Silvio Danese, Miquel Sans, Franco Scaldaferri, Alessandro Sgambato, Sergio Rutella, Achille Cittadini, Josep M. Piqué, Julian Panes, Jeffry A. Katz, Antonio Gasbarrini, and Claudio Fiocchi
J Immunol 2006 176: 2617-2624. [Abstract] [Full Text] [PDF]  

Persistent Cytomegalovirus-Specific Memory Responses in the Lung Allograft and Blood following Primary Infection in Lung Transplant Recipients

Oksana A. Shlobin, Erin E. West, Noah Lechtzin, Susan M. Miller, Marvin Borja, Jonathan B. Orens, Lesia K. Dropulic, and John F. McDyer
J Immunol 2006 176: 2625-2634. [Abstract] [Full Text] [PDF]  

Tolerance Induction by Transcutaneous Immunization through Ultraviolet-Irradiated Skin Is Transferable through CD4⁺CD25⁺ T Regulatory Cells and Is Dependent on Host-Derived IL-10

Mehran Ghoreishi and Jan P. Dutz
J Immunol 2006 176: 2635-2644. [Abstract] [Full Text] [PDF]  

Longitudinal Studies of Clonally Expanded CD8 T Cells Reveal a Repertoire Shrinkage Predicting Mortality and an Increased Number of Dysfunctional Cytomegalovirus-Specific T Cells in the Very Elderly

Sine Reker Hadrup, Jan Strindhall, Tania Køllgaard, Tina Seremet, Boo Johansson, Graham Pawelec, Per thor Straten, and Anders Wikby
J Immunol 2006 176: 2645-2653. [Abstract] [Full Text] [PDF]  

B Cells Are Crucial for Determinant Spreading of T Cell Autoimmunity among Cell Antigens in Diabetes-Prone Nonobese Diabetic Mice

Jide Tian, Dan Zekzer, Yuxin Lu, Hoa Dang, and Daniel L. Kaufman
J Immunol 2006 176: 2654-2661. [Abstract] [Full Text] [PDF]  

HIV-Specific Cytotoxic Cell Frequencies Measured Directly Ex Vivo by the Lysispot Assay Can Be Higher or Lower Than the Frequencies of IFN--Secreting Cells: Anti-HIV Cytotoxicity Is Not Generally Impaired Relative to Other Chronic Virus Responses

Jennifer E. Snyder-Cappione, Anagha A. Divekar, Genny M. Maupin, Xia Jin, Lisa M. Demeter, and Tim R. Mosmann
J Immunol 2006 176: 2662-2668. [Abstract] [Full Text] [PDF]  

CORRECTIONS:

Constitutively active protein kinase B enhances Lck and Erk activities and influences thymocyte selection and activation.

S.-Y. Na, A. Patra, Y. Scheuring, A. Marx, M. Tolaini, D. Kioussis, B. Hemmings, T. Hünig, and U. Bommhardt
J Immunol 2006 176: 2669. [Full Text] [PDF]  

Identification of high and low responders to lipopolysaccharide in normal subjects: an unbiased approach to identify modulators of innate immunity

M. M. Wurfel, W. Y. Park, F. Radella, J. Ruzinski, A. Sandstrom, J. Strout, R. E. Bumgarner, and T. R. Martin
J Immunol 2006 176: 2669. [Full Text] [PDF]  

HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent

Y.-J. Jin, C. Y. Cai, X. Zhang, H.-T. Zhang, J. A. Hirst, and S. J. Burakoff
J Immunol 2006 176: 2669. [Full Text] [PDF]  

The Nef protein of HIV-1 induces loss of cell surface costimulatory molecules CD80 and CD86 in APCs

A. Chaudhry, S. R. Das, A. Hussain, S. Mayor, A. George, V. Bal, S. Jameel, and S. Rath
J Immunol 2006 176: 2670. [Full Text] [PDF]  

Defined blocks in terminal plasma cell differentiation of common variable immunodeficiency patients

N. Taubenheim, M. von Hornung, A. Durandy, K. Warnatz, L. Corcoran, H.-H. Peter, and H. Eibel
J Immunol 2006 176: 2670. [Full Text] [PDF]  

Granzyme B, a new player in activation-induced cell death, is down-regulated by vasoactive intestinal peptide in Th2 but not Th1 effectors

V. Sharma, M. Delgado, and D. Ganea
J Immunol 2006 176: 2670. [Full Text] [PDF]  

B7⁺ iris pigment epithelium induce CD8⁺ T regulatory cells; both suppress CTLA-4⁺ T cells

S. Sugita, T. F. Ng, P. J. Lucas, R. E. Gress, and J. W. Streilein
J Immunol 2006 176: 2670. [Full Text] [PDF]  

Gap junction-mediated intercellular communication between dendritic cells (DCs) is required for effective activation of DCs

H. Matsue, J. Yao, K. Matsue, A. Nagasaka, H. Sugiyama, R. Aoki, M. Kitamura, and S. Shimada
J Immunol 2006 176: 2670. [Full Text]  

Chemotactic responses of IL-4-, IL-10-, and IFN--producing CD4⁺ T cells depend on tissue origin and microbial stimulus

G. F. Debes, M. E. Dahl, A. J. Mahiny, K. Bonhagen, D. J. Campbell, K. Siegmund, K. J. Erb, D. B. Lewis, T. Kamradt, and A. Hamann
J Immunol 2006 176: 2671. [Full Text] [PDF]  

Lipoteichoic acid-induced nitric oxide production depends on the activation of platelet-activating factor receptor and Jak2

S. H. Han, J. H. Kim, H. S. Seo, M. H. Martin, G.-H. Chung, S. M. Michalek, and M. H. Nahm
J Immunol 2006 176: 2671. [Full Text] [PDF]  

Innate stimuli accentuate end-organ damage by nephrotoxic antibodies via Fc receptor and TLR stimulation and IL-1/TNF- production

Y. Fu, C. Xie, J. Chen, J. Zhu, H. Zhou, J. Thomas, X. J. Zhou, and C. Mohan
J Immunol 2006 176: 2671. [Full Text] [PDF]  

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