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Contents: Volume 174 / No. 5 / March 1, 2005   [Index by Author] 
       IN THIS ISSUE
       PILLARS OF IMMUNOLOGY
       BRIEF REVIEWS
       CUTTING EDGE
       CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
       MOLECULAR AND STRUCTURAL IMMUNOLOGY
       IMMUNOGENETICS
       HOST DEFENSE
       INFLAMMATION
       CLINICAL IMMUNOLOGY
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IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2005 174: 2447-2449. [Full Text] [PDF]  

PILLARS OF IMMUNOLOGY:

Monoclonal Antibodies: Producing Magic Bullets by Somatic Cell Hybridization
David H. Margulies
J Immunol 2005 174: 2451-2452. [Full Text] [PDF] [Original Pillars Article]  

Pillars Article: Continuous cultures of fused cells secreting antibody of predefined specificity. Nature, 1975, 256 (5517): 495–497.
G. Köhler and C. Milstein
J Immunol 2005 174: 2453-2455. [PDF]  

BRIEF REVIEWS:

Variegation of the Immune Response with Dendritic Cells and Pathogen Recognition Receptors
Bali Pulendran
J Immunol 2005 174: 2457-2465. [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: All-trans Retinoic Acid Down-Regulates TLR2 Expression and Function
Philip T. Liu, Stephan R. Krutzik, Jenny Kim, and Robert L. Modlin
J Immunol 2005 174: 2467-2470. [Abstract] [Full Text] [PDF]  

Cutting Edge: Microbial Products Elicit Formation of Dendritic Cell Aggresome-Like Induced Structures in Macrophages
Veronica Canadien, Tracy Tan, Rachelle Zilber, Jason Szeto, Andrew J. Perrin, and John H. Brumell
J Immunol 2005 174: 2471-2475. [Abstract] [Full Text] [PDF] Data Supplement  

Cutting Edge: Priming of CTL by Transcutaneous Peptide Immunization with Imiquimod
Gerd Rechtsteiner, Tobias Warger, Philipp Osterloh, Hansjörg Schild, and Markus P. Radsak
J Immunol 2005 174: 2476-2480. [Abstract] [Full Text] [PDF]  

Cutting Edge: p27Kip1 Deficiency Reduces the Requirement for CD28-Mediated Costimulation in Naive CD8+ but Not CD4+ T Lymphocytes
Lawrence A. Wolfraim and John J. Letterio
J Immunol 2005 174: 2481-2484. [Abstract] [Full Text] [PDF]  

Cutting Edge: Regulation of T Cell Trafficking and Primary Immune Responses by Sphingosine 1-Phosphate Receptor 1
Hongbo Chi and Richard A. Flavell
J Immunol 2005 174: 2485-2488. [Abstract] [Full Text] [PDF]  

Cutting Edge: Back to "One-Way" Germinal Centers
Michael E. Meyer-Hermann and Philip K. Maini
J Immunol 2005 174: 2489-2493. [Abstract] [Full Text] [PDF]  

Cutting Edge: IL-4 Induces Suppressor of Cytokine Signaling-3 Expression in B Cells by a Mechanism Dependent on Activation of p38 MAPK
Stephen Canfield, Youngnam Lee, Andreas Schröder, and Paul Rothman
J Immunol 2005 174: 2494-2498. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

IFN-{alpha} Induces Early Lethal Lupus in Preautoimmune (New Zealand Black x New Zealand White)F1 but Not in BALB/c Mice
Alexis Mathian, Arthur Weinberg, Mike Gallegos, Jacques Banchereau, and Sophie Koutouzov
J Immunol 2005 174: 2499-2506. [Abstract] [Full Text] [PDF]  

Polycomb Group Gene mel-18 Regulates Early T Progenitor Expansion by Maintaining the Expression of Hes-1, a Target of the Notch Pathway
Masaki Miyazaki, Hiroshi Kawamoto, Yuko Kato, Manami Itoi, Kazuko Miyazaki, Kyoko Masuda, Satoshi Tashiro, Hiroto Ishihara, Kazuhiko Igarashi, Takashi Amagai, Rieko Kanno, and Masamoto Kanno
J Immunol 2005 174: 2507-2516. [Abstract] [Full Text] [PDF]  

Naive, Effector, and Memory T Lymphocytes Efficiently Scan Dendritic Cells In Vivo: Contact Frequency in T Cell Zones of Secondary Lymphoid Organs Does Not Depend on LFA-1 Expression and Facilitates Survival of Effector T Cells
Jürgen Westermann, Ulrike Bode, Andrea Sahle, Uwe Speck, Nathan Karin, Eric B. Bell, Kathrin Kalies, and Andreas Gebert
J Immunol 2005 174: 2517-2524. [Abstract] [Full Text] [PDF]  

Thymic Anlage Is Colonized by Progenitors Restricted to T, NK, and Dendritic Cell Lineages
Kyoko Masuda, Manami Itoi, Takashi Amagai, Nagahiro Minato, Yoshimoto Katsura, and Hiroshi Kawamoto
J Immunol 2005 174: 2525-2532. [Abstract] [Full Text] [PDF]  

Antiangiogenic Drugs Synergize with a Membrane Macrophage Colony-Stimulating Factor-Based Tumor Vaccine to Therapeutically Treat Rats with an Established Malignant Intracranial Glioma
Edward W. B. Jeffes, Jian Gang Zhang, Neil Hoa, Animesh Petkar, Christina Delgado, Samuel Chong, Andre Obenaus, Ramon Sanchez, Sakineh Khalaghizadeh, Tetyana Khomenko, Brandon A. Knight, Reza Alipanah, Tuong-Vi Nguyen, Chirag Shah, Seema Vohra, Jing-Li Zhuang, Jessie Liu, H. Terry Wepsic, and Martin R. Jadus
J Immunol 2005 174: 2533-2543. [Abstract] [Full Text] [PDF]  

Regulated Folding of Tyrosinase in the Endoplasmic Reticulum Demonstrates That Misfolded Full-Length Proteins Are Efficient Substrates for Class I Processing and Presentation
Marina Ostankovitch, Valentina Robila, and Victor H. Engelhard
J Immunol 2005 174: 2544-2551. [Abstract] [Full Text] [PDF]  

Progressive and Controlled Development of Mouse Dendritic Cells from Flt3+CD11b+ Progenitors In Vitro
Thomas Hieronymus, Tatjana C. Gust, Ralf D. Kirsch, Thorsten Jorgas, Gitta Blendinger, Mykola Goncharenko, Kamilla Supplitt, Stefan Rose-John, Albrecht M. Müller, and Martin Zenke
J Immunol 2005 174: 2552-2562. [Abstract] [Full Text] [PDF] Data Supplement  

The Fate of Low Affinity Tumor-Specific CD8+ T Cells in Tumor-Bearing Mice
Michael A. Lyman, C. Thomas Nugent, Kristi L. Marquardt, Judith A. Biggs, Eric G. Pamer, and Linda A. Sherman
J Immunol 2005 174: 2563-2572. [Abstract] [Full Text] [PDF]  

IFN Regulatory Factor-4 and -8 Govern Dendritic Cell Subset Development and Their Functional Diversity
Tomohiko Tamura, Prafullakumar Tailor, Kunihiro Yamaoka, Hee Jeong Kong, Hideki Tsujimura, John J. O’Shea, Harinder Singh, and Keiko Ozato
J Immunol 2005 174: 2573-2581. [Abstract] [Full Text] [PDF]  

CXC Chemokine Ligand 12-Induced Focal Adhesion Kinase Activation and Segregation into Membrane Domains Is Modulated by Regulator of G Protein Signaling 1 in Pro-B Cells
Yi Le, Marek Honczarenko, Aleksandra M. Glodek, Daniel K. Ho, and Leslie E. Silberstein
J Immunol 2005 174: 2582-2590. [Abstract] [Full Text] [PDF]  

CD8+ T Cell Immunity Against a Tumor/Self-Antigen Is Augmented by CD4+ T Helper Cells and Hindered by Naturally Occurring T Regulatory Cells
Paul A. Antony, Ciriaco A. Piccirillo, Akgül Akpinarli, Steven E. Finkelstein, Paul J. Speiss, Deborah R. Surman, Douglas C. Palmer, Chi-Chao Chan, Christopher A. Klebanoff, Willem W. Overwijk, Steven A. Rosenberg, and Nicholas P. Restifo
J Immunol 2005 174: 2591-2601. [Abstract] [Full Text] [PDF]  

The Wiskott-Aldrich Syndrome Protein Regulates Nuclear Translocation of NFAT2 and NF-{kappa}B (RelA) Independently of Its Role in Filamentous Actin Polymerization and Actin Cytoskeletal Rearrangement
Winifred Huang, Hans D. Ochs, Bo Dupont, and Yatin M. Vyas
J Immunol 2005 174: 2602-2611. [Abstract] [Full Text] [PDF]  

Natural Killer Dendritic Cells Have Both Antigen Presenting and Lytic Function and in Response to CpG Produce IFN-{gamma} via Autocrine IL-12
Venu G. Pillarisetty, Steven C. Katz, Joshua I. Bleier, Alaap B. Shah, and Ronald P. DeMatteo
J Immunol 2005 174: 2612-2618. [Abstract] [Full Text] [PDF]  

Activated Human B Lymphocytes Express Cyclooxygenase-2 and Cyclooxygenase Inhibitors Attenuate Antibody Production
Elizabeth P. Ryan, Stephen J. Pollack, Thomas I. Murant, Steven H. Bernstein, Raymond E. Felgar, and Richard P. Phipps
J Immunol 2005 174: 2619-2626. [Abstract] [Full Text] [PDF]  

Overexpression of the Runx3 Transcription Factor Increases the Proportion of Mature Thymocytes of the CD8 Single-Positive Lineage
Kazuyoshi Kohu, Takehito Sato, Shin-ichiro Ohno, Keitaro Hayashi, Ryuji Uchino, Natsumi Abe, Megumi Nakazato, Naomi Yoshida, Toshiaki Kikuchi, Yoichiro Iwakura, Yoshihiro Inoue, Toshio Watanabe, Sonoko Habu, and Masanobu Satake
J Immunol 2005 174: 2627-2636. [Abstract] [Full Text] [PDF]  

The Human CD1-Restricted T Cell Repertoire Is Limited to Cross-Reactive Antigens: Implications for Host Responses against Immunologically Related Pathogens
Peter A. Sieling, Jordi B. Torrelles, Steffen Stenger, Woosin Chung, Anne E. Burdick, Thomas H. Rea, Patrick J. Brennan, John T. Belisle, Steven A. Porcelli, and Robert L. Modlin
J Immunol 2005 174: 2637-2644. [Abstract] [Full Text] [PDF]  

In Vivo Manipulation of Dendritic Cells Overcomes Tolerance to Unmodified Tumor-Associated Self Antigens and Induces Potent Antitumor Immunity
Fumiyoshi Okano, Miriam Merad, Katsuyoshi Furumoto, and Edgar G. Engleman
J Immunol 2005 174: 2645-2652. [Abstract] [Full Text] [PDF]  

Tumor-Induced Apoptosis of Human IL-2-Activated NK Cells: Role of Natural Cytotoxicity Receptors
Alessandro Poggi, Anna-Maria Massaro, Simone Negrini, Paola Contini, and Maria Raffaella Zocchi
J Immunol 2005 174: 2653-2660. [Abstract] [Full Text] [PDF]  

Recognition of a New ARTC1 Peptide Ligand Uniquely Expressed in Tumor Cells by Antigen-Specific CD4+ Regulatory T Cells
Helen Y. Wang, Guangyong Peng, Zhong Guo, Ethan M. Shevach, and Rong-Fu Wang
J Immunol 2005 174: 2661-2670. [Abstract] [Full Text] [PDF]  

Mismatched Antigen Prepares {gamma}{delta} T Cells for Suppression of Airway Hyperresponsiveness
Niyun Jin, Christian Taube, Laura Sharp, Youn-Soo Hahn, Xiang Yin, J. M. Wands, Christina L. Roark, Rebecca L. O’Brien, Erwin W. Gelfand, and Willi K. Born
J Immunol 2005 174: 2671-2679. [Abstract] [Full Text] [PDF]  

Platelet Factor 4 Differentially Modulates CD4+CD25+ (Regulatory) versus CD4+CD25 (Nonregulatory) T Cells
Chao Yan Liu, Manuela Battaglia, Seon Ho Lee, Qi-Hong Sun, Richard H. Aster, and Gian Paolo Visentin
J Immunol 2005 174: 2680-2686. [Abstract] [Full Text] [PDF]  

CD38 Signaling Regulates B Lymphocyte Activation via a Phospholipase C (PLC)-{gamma}2-Independent, Protein Kinase C, Phosphatidylcholine-PLC, and Phospholipase D-Dependent Signaling Cascade
Miguel E. Moreno-García, Lucia N. López-Bojórques, Alejandro Zentella, Lisa A. Humphries, David J. Rawlings, and Leopoldo Santos-Argumedo
J Immunol 2005 174: 2687-2695. [Abstract] [Full Text] [PDF]  

Differential Effects of IL-21 during Initiation and Progression of Autoimmunity against Neuroantigen
Timothy L. Vollmer, Ruolan Liu, Mary Price, Susan Rhodes, Antonio La Cava, and Fu-Dong Shi
J Immunol 2005 174: 2696-2701. [Abstract] [Full Text] [PDF]  

Two Structurally Related Rat Ly49 Receptors with Opposing Functions (Ly49 Stimulatory Receptor 5 and Ly49 Inhibitory Receptor 5) Recognize Nonclassical MHC Class Ib-Encoded Target Ligands
Christian Naper, Ke-Zheng Dai, Lise Kveberg, Bent Rolstad, Eréne C. Niemi, John T. Vaage, and James C. Ryan
J Immunol 2005 174: 2702-2711. [Abstract] [Full Text] [PDF]  

Inhibition of Granulocyte-Macrophage Colony-Stimulating Factor Signaling and Microglial Proliferation by Anti-CD45RO: Role of Hck Tyrosine Kinase and Phosphatidylinositol 3-Kinase/Akt
Hyeon-Sook Suh, Mee-Ohk Kim, and Sunhee C. Lee
J Immunol 2005 174: 2712-2719. [Abstract] [Full Text] [PDF]  

IL-6 Plays a Unique Role in Initiating c-Maf Expression during Early Stage of CD4 T Cell Activation
Yu Yang, Jordi Ochando, Adam Yopp, Jonathan S. Bromberg, and Yaozhong Ding
J Immunol 2005 174: 2720-2729. [Abstract] [Full Text] [PDF]  

In Vivo and in Absence of a Thymus, the Enforced Expression of the Notch Ligands Delta-1 or Delta-4 Promotes T Cell Development with Specific Unique Effects
Alix de La Coste, Emmanuelle Six, Nicolas Fazilleau, Laurent Mascarell, Nicolas Legrand, Marie-Pierre Mailhé, Ana Cumano, Yacine Laâbi, and Antonio A. Freitas
J Immunol 2005 174: 2730-2737. [Abstract] [Full Text] [PDF]  

Pro-IL-16 Regulation in Activated Murine CD4+ Lymphocytes
Fucheng Ren, Xin Zhan, Gregory Martens, Jinhee Lee, David Center, Sue Kim Hanson, and Hardy Kornfeld
J Immunol 2005 174: 2738-2745. [Abstract] [Full Text] [PDF]  

Different Diabetogenic Potential of Autoaggressive CD8+ Clones Associated with IFN-{gamma}-Inducible Protein 10 (CXC Chemokine Ligand 10) Production but Not Cytokine Expression, Cytolytic Activity, or Homing Characteristics
Mette Ejrnaes, Nicoline Videbaek, Urs Christen, Anne Cooke, Birgitte K. Michelsen, and Matthias von Herrath
J Immunol 2005 174: 2746-2755. [Abstract] [Full Text] [PDF]  

Inability of bm14 Mice to Respond to Theiler’s Murine Encephalomyelitis Virus Is Caused by Defective Antigen Presentation, Not Repertoire Selection
Matthew S. Block, Yanice V. Mendez-Fernandez, Virginia P. Van Keulen, Michael J. Hansen, Kathleen S. Allen, Anya L. Taboas, Moses Rodriguez, and Larry R. Pease
J Immunol 2005 174: 2756-2762. [Abstract] [Full Text] [PDF]  

The Impact of Misfolding versus Targeted Degradation on the Efficiency of the MHC Class I-Restricted Antigen Processing
Tatiana N. Golovina, Susan E. Morrison, and Laurence C. Eisenlohr
J Immunol 2005 174: 2763-2769. [Abstract] [Full Text] [PDF]  

Constitutively Active Aryl Hydrocarbon Receptor Expressed Specifically in T-Lineage Cells Causes Thymus Involution and Suppresses the Immunization-Induced Increase in Splenocytes
Keiko Nohara, Xiaoqing Pan, Shin-ichi Tsukumo, Azumi Hida, Tomohiro Ito, Haruko Nagai, Kaoru Inouye, Hozumi Motohashi, Masayuki Yamamoto, Yoshiaki Fujii-Kuriyama, and Chiharu Tohyama
J Immunol 2005 174: 2770-2777. [Abstract] [Full Text] [PDF]  

Overlapping Signaling Pathways of Sphingosine 1-Phosphate and TGF-{beta} in the Murine Langerhans Cell Line XS52
Heinfried H. Radeke, Henrik von Wenckstern, Kirsten Stoidtner, Bettina Sauer, Stefanie Hammer, and Burkhard Kleuser
J Immunol 2005 174: 2778-2786. [Abstract] [Full Text] [PDF]  

Generation of Antigen-Specific, Foxp3-Expressing CD4+ Regulatory T Cells by Inhibition of APC Proteosome Function
Yingzi Cong, Astrid Konrad, Nuzhat Iqbal, Robin D. Hatton, Casey T. Weaver, and Charles O. Elson
J Immunol 2005 174: 2787-2795. [Abstract] [Full Text] [PDF]  

Synergistic Effect of IL-2, IL-12, and IL-18 on Thymocyte Apoptosis and Th1/Th2 Cytokine Expression
Maria Cecilia Rodriguez-Galán, Jay H. Bream, Andrew Farr, and Howard A. Young
J Immunol 2005 174: 2796-2804. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

IgH V-Region Sequence Does Not Predict the Survival Fate of Human Germinal Center B Cells
Stephen M. Jackson and J. Donald Capra
J Immunol 2005 174: 2805-2813. [Abstract] [Full Text] [PDF]  

EBV-Induced Gene 3 Transcription Is Induced by TLR Signaling in Primary Dendritic Cells via NF-{kappa}B Activation
Stefan Wirtz, Christoph Becker, Massimo C. Fantini, Edward E. Nieuwenhuis, Ingrid Tubbe, Peter R. Galle, Hans-Jörg Schild, Mark Birkenbach, Richard S. Blumberg, and Markus F. Neurath
J Immunol 2005 174: 2814-2824. [Abstract] [Full Text] [PDF]  

Involvement of TNF and NF-{kappa}B in the Transcriptional Control of Cyclooxygenase-2 Expression by IFN-{gamma} in Macrophages
Virginia Vila-del Sol and Manuel Fresno
J Immunol 2005 174: 2825-2833. [Abstract] [Full Text] [PDF]  

The Ig{kappa}3' Enhancer Is Activated by Gradients of Chromatin Accessibility and Protein Association
Daniel C. McDevit, Leslie Perkins, Michael L. Atchison, and Barbara S. Nikolajczyk
J Immunol 2005 174: 2834-2842. [Abstract] [Full Text] [PDF]  

Proteolytic Regulation of Activated STAT6 by Calpains
Jose Zamorano, Maria Dolores Rivas, Fernando Setien, and Moises Perez-G
J Immunol 2005 174: 2843-2848. [Abstract] [Full Text] [PDF]  

Localization of Src Homology 2 Domain-Containing Phosphatase 1 (SHP-1) to Lipid Rafts in T Lymphocytes: Functional Implications and a Role for the SHP-1 Carboxyl Terminus
Vicki C. J. Fawcett and Ulrike Lorenz
J Immunol 2005 174: 2849-2859. [Abstract] [Full Text] [PDF]  

In Situ Diversification of the Antibody Repertoire in Chronic Lyme Arthritis Synovium
Srimoyee Ghosh, Allen C. Steere, B. David Stollar, and Brigitte T. Huber
J Immunol 2005 174: 2860-2869. [Abstract] [Full Text] [PDF]  

The Two Major Oligomeric Forms of Human Mannan-Binding Lectin: Chemical Characterization, Carbohydrate-Binding Properties, and Interaction with MBL-Associated Serine Proteases
Florence Teillet, Bernard Dublet, Jean-Pierre Andrieu, Christine Gaboriaud, Gérard J. Arlaud, and Nicole M. Thielens
J Immunol 2005 174: 2870-2877. [Abstract] [Full Text] [PDF]  

Interactions between NKG2x Immunoreceptors and HLA-E Ligands Display Overlapping Affinities and Thermodynamics
Brett K. Kaiser, Fariba Barahmand-pour, Wendy Paulsene, Scott Medley, Daniel E. Geraghty, and Roland K. Strong
J Immunol 2005 174: 2878-2884. [Abstract] [Full Text] [PDF]  

IMMUNOGENETICS:

Hagfish Leukocytes Express a Paired Receptor Family with a Variable Domain Resembling Those of Antigen Receptors
Takashi Suzuki, Tadasu Shin-I, Asao Fujiyama, Yuji Kohara, and Masanori Kasahara
J Immunol 2005 174: 2885-2891. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Intracellular Salmonella Inhibit Antigen Presentation by Dendritic Cells
Cédric Cheminay, Annette Möhlenbrink, and Michael Hensel
J Immunol 2005 174: 2892-2899. [Abstract] [Full Text] [PDF]  

Loss of CD127 Expression Defines an Expansion of Effector CD8+ T Cells in HIV-Infected Individuals
Mirko Paiardini, Barbara Cervasi, Helmut Albrecht, Alagarraju Muthukumar, Richard Dunham, Shari Gordon, Henry Radziewicz, Giuseppe Piedimonte, Mauro Magnani, Maria Montroni, Susan M. Kaech, Amy Weintrob, John D. Altman, Donald L. Sodora, Mark B. Feinberg, and Guido Silvestri
J Immunol 2005 174: 2900-2909. [Abstract] [Full Text] [PDF]  

A Crucial Role for Tryptophan Catabolism at the Host/Candida albicans Interface
Silvia Bozza, Francesca Fallarino, Lucia Pitzurra, Teresa Zelante, Claudia Montagnoli, Silvia Bellocchio, Paolo Mosci, Carmine Vacca, Paolo Puccetti, and Luigina Romani
J Immunol 2005 174: 2910-2918. [Abstract] [Full Text] [PDF]  

Development and Migration of Protective CD8+ T Cells into the Nervous System following Ocular Herpes Simplex Virus-1 Infection
Anna Lang and Janko Nikolich-Zugich
J Immunol 2005 174: 2919-2925. [Abstract] [Full Text] [PDF]  

The Staphylococcal Superantigen-Like Protein 7 Binds IgA and Complement C5 and Inhibits IgA-Fc{alpha}RI Binding and Serum Killing of Bacteria
Ries Langley, Bruce Wines, Natasha Willoughby, Indira Basu, Thomas Proft, and John D. Fraser
J Immunol 2005 174: 2926-2933. [Abstract] [Full Text] [PDF]  

Nonhealing Infection despite Th1 Polarization Produced by a Strain of Leishmania major in C57BL/6 Mice
Charles F. Anderson, Susana Mendez, and David L. Sacks
J Immunol 2005 174: 2934-2941. [Abstract] [Full Text] [PDF]  

Human TLR10 Is a Functional Receptor, Expressed by B Cells and Plasmacytoid Dendritic Cells, Which Activates Gene Transcription through MyD88
Uzma Hasan, Claire Chaffois, Claude Gaillard, Virginie Saulnier, Estelle Merck, Sandra Tancredi, Chantal Guiet, Francine Brière, Jaromir Vlach, Serge Lebecque, Giorgio Trinchieri, and Elizabeth E. M. Bates
J Immunol 2005 174: 2942-2950. [Abstract] [Full Text] [PDF]  

Breast Milk-Derived Antigen-Specific CD8+ T Cells: An Extralymphoid Effector Memory Cell Population in Humans
Steffanie Sabbaj, Mrinal K. Ghosh, Bradley H. Edwards, Ruth Leeth, W. Don Decker, Paul A. Goepfert, and Grace M. Aldrovandi
J Immunol 2005 174: 2951-2956. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

CD4+CD25+ Regulatory T Cells Control Innate Immune Reactivity after Injury
Thomas J. Murphy, Niamh Ni Choileain, Yan Zang, John A. Mannick, and James A. Lederer
J Immunol 2005 174: 2957-2963. [Abstract] [Full Text] [PDF]  

Pseudomonas aeruginosa Lipopolysaccharide Induction of Keratinocyte Proliferation, NF-{kappa}B, and Cyclin D1 Is Inhibited by Indomethacin
Diego Preciado, Emiro Caicedo, Rajat Jhanjee, Rob Silver, George Harris, Steven K. Juhn, Dan I. Choo, and Frank Ondrey
J Immunol 2005 174: 2964-2973. [Abstract] [Full Text] [PDF]  

The Production of IL-1 Receptor Antagonist in IFN-{beta}-Stimulated Human Monocytes Depends on the Activation of Phosphatidylinositol 3-Kinase but Not of STAT1
Nicolas Molnarfi, Nevila Hyka-Nouspikel, Lyssia Gruaz, Jean-Michel Dayer, and Danielle Burger
J Immunol 2005 174: 2974-2980. [Abstract] [Full Text] [PDF]  

Lysophosphatidylcholine Modulates Neutrophil Oxidant Production through Elevation of Cyclic AMP
Phoebe Lin, Emily J. Welch, Xiao-Pei Gao, Asrar B. Malik, and Richard D. Ye
J Immunol 2005 174: 2981-2989. [Abstract] [Full Text] [PDF]  

IL-10 Gene-Deficient Mice Lack TGF-{beta}/Smad Signaling and Fail to Inhibit Proinflammatory Gene Expression in Intestinal Epithelial Cells after the Colonization with Colitogenic Enterococcus faecalis
Pedro A. Ruiz, Anna Shkoda, Sandra C. Kim, R. Balfour Sartor, and Dirk Haller
J Immunol 2005 174: 2990-2999. [Abstract] [Full Text] [PDF]  

B7RP-1 Is Not Required for the Generation of Th2 Responses in a Model of Allergic Airway Inflammation but Is Essential for the Induction of Inhalation Tolerance
Beata U. Gajewska, Anna Tafuri, Filip K. Swirski, Tina Walker, Jill R. Johnson, Theresa Shea, Arda Shahinian, Susanna Goncharova, Tak W. Mak, Martin R. Stämpfli, and Manel Jordana
J Immunol 2005 174: 3000-3005. [Abstract] [Full Text] [PDF]  

Identification of a Peptide Derived from Vaccinia Virus A52R Protein That Inhibits Cytokine Secretion in Response to TLR-Dependent Signaling and Reduces In Vivo Bacterial-Induced Inflammation
Sharon L. McCoy, Stephen E. Kurtz, Carol J. MacArthur, Dennis R. Trune, and Steven H. Hefeneider
J Immunol 2005 174: 3006-3014. [Abstract] [Full Text] [PDF]  

Enhanced Apoptotic Cell Clearance Capacity and B Cell Survival Factor Production by IL-10-Activated Macrophages: Implications for Burkitt’s Lymphoma
Carol Anne Ogden, John D. Pound, Balvinder K. Batth, Sarah Owens, Ingolfur Johannessen, Katrina Wood, and Christopher D. Gregory
J Immunol 2005 174: 3015-3023. [Abstract] [Full Text] [PDF]  

Suppressors of Cytokine Signaling-1 and -3 Regulate Osteoclastogenesis in the Presence of Inflammatory Cytokines
Masanobu Ohishi, Yumiko Matsumura, Daisuke Aki, Ryuichi Mashima, Koji Taniguchi, Takashi Kobayashi, Toshio Kukita, Yukihide Iwamoto, and Akihiko Yoshimura
J Immunol 2005 174: 3024-3031. [Abstract] [Full Text] [PDF]  

Tumor Cells Deactivate Human Monocytes by Up-Regulating IL-1 Receptor Associated Kinase-M Expression via CD44 and TLR4
Carlos del Fresno, Karel Otero, Lourdes Gómez-García, Maria Carmen González-León, Llanos Soler-Ranger, Pablo Fuentes-Prior, Pedro Escoll, Rosa Baos, Luis Caveda, Felipe García, Francisco Arnalich, and Eduardo López-Collazo
J Immunol 2005 174: 3032-3040. [Abstract] [Full Text] [PDF]  

Macrophages Induce the Inflammatory Response in the Pulmonary Arthus Reaction through G{alpha}i2 Activation That Controls C5aR and Fc Receptor Cooperation
Julia Skokowa, Syed R. Ali, Olga Felda, Varsha Kumar, Stephanie Konrad, Nelli Shushakova, Reinhold E. Schmidt, Roland P. Piekorz, Bernd Nürnberg, Karsten Spicher, Lutz Birnbaumer, Jörg Zwirner, Jill W. C. Claassens, Josef S. Verbeek, Nico van Rooijen, Jörg Köhl, and J. Engelbert Gessner
J Immunol 2005 174: 3041-3050. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Alloreactive Memory T Cells Are Responsible for the Persistence of Graft-versus-Host Disease
Yi Zhang, Gerard Joe, Elizabeth Hexner, Jiang Zhu, and Stephen G. Emerson
J Immunol 2005 174: 3051-3058. [Abstract] [Full Text] [PDF]  

Processing of C3b-Opsonized Immune Complexes Bound to Non-Complement Receptor 1 (CR1) Sites on Red Cells: Phagocytosis, Transfer, and Associations with CR1
Maria L. Craig, John N. Waitumbi, and Ronald P. Taylor
J Immunol 2005 174: 3059-3066. [Abstract] [Full Text] [PDF]  

Increased Blood Myeloid Dendritic Cells and Dendritic Cell-Poietins in Langerhans Cell Histiocytosis
Alexandre Rolland, Lydie Guyon, Michelle Gill, Yi-Hong Cai, Jacques Banchereau, Kenneth McClain, and A. Karolina Palucka
J Immunol 2005 174: 3067-3071. [Abstract] [Full Text] [PDF]  

Induction by IL-1{beta} of Tissue Inhibitor of Metalloproteinase-1 in Human Orbital Fibroblasts: Modulation of Gene Promoter Activity by IL-4 and IFN-{gamma}
Rui Han and Terry J. Smith
J Immunol 2005 174: 3072-3079. [Abstract] [Full Text] [PDF]  

MAGE-A1-, MAGE-A10-, and gp100-Derived Peptides Are Immunogenic When Combined with Granulocyte-Macrophage Colony-Stimulating Factor and Montanide ISA-51 Adjuvant and Administered as Part of a Multipeptide Vaccine for Melanoma
Kimberly A. Chianese-Bullock, Jennifer Pressley, Courtney Garbee, Sarah Hibbitts, Cheryl Murphy, Galina Yamshchikov, Gina R. Petroni, Eric A. Bissonette, Patrice Y. Neese, William W. Grosh, Priscilla Merrill, Robyn Fink, Elizabeth M. H. Woodson, Catherine J. Wiernasz, James W. Patterson, and Craig L. Slingluff, Jr
J Immunol 2005 174: 3080-3086. [Abstract] [Full Text] [PDF]  

Generation of an Optimized Polyvalent Monocyte-Derived Dendritic Cell Vaccine by Transfecting Defined RNAs after Rather Than before Maturation
Niels Schaft, Jan Dörrie, Peter Thumann, Verena E. Beck, Ina Müller, Erwin S. Schultz, Eckhart Kämpgen, Detlef Dieckmann, and Gerold Schuler
J Immunol 2005 174: 3087-3097. [Abstract] [Full Text] [PDF]  

Effect of Human Cytomegalovirus on Expression of MHC Class I-Related Chains A
Yizhou Zou, Wade Bresnahan, R. Travis Taylor, and Peter Stastny
J Immunol 2005 174: 3098-3104. [Abstract] [Full Text] [PDF]  

Thyroxine-Binding Antibodies Inhibit T Cell Recognition of a Pathogenic Thyroglobulin Epitope
Yang D. Dai, Petros Eliades, Karen A. Carayanniotis, Daniel J. McCormick, Yi-chi M. Kong, Vassiliki Magafa, Paul Cordopatis, Peggy Lymberi, and George Carayanniotis
J Immunol 2005 174: 3105-3110. [Abstract] [Full Text] [PDF]  

H2A- and H2E-Derived CD4+CD25+ Regulatory T Cells: A Potential Role in Reciprocal Inhibition by Class II Genes in Autoimmune Thyroiditis
Gerald P. Morris, Yan Yan, Chella S. David, and Yi-chi M. Kong
J Immunol 2005 174: 3111-3116. [Abstract] [Full Text] [PDF]  

ICOS-B7 Homologous Protein Interactions Are Necessary for Mercury-Induced Autoimmunity
Yan Zheng, Monika Jost, John P. Gaughan, Reiner Class, Anthony J. Coyle, and Marc Monestier
J Immunol 2005 174: 3117-3121. [Abstract] [Full Text] [PDF]  

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