The JI -- Collected Papers: Pillars of Immunology

List of All Pillars of Immunology articles

From the Current Issue: December 2009; 183 (11) [Table of Contents]

Toshiaki Kawakami: A Crucial Door to the Mast Cell Mystery Knocked In
J Immunol 2009 183: 6861-6862 [Full Text] [PDF] [Original Pillars Article]

Toru Nakano, Takashi Sonoda, Chieko Hayashi, Atsushi Yamatodani, Yoshio Kanayama, Tei-Ichi Yamamura, Hidekazu Asai, Takeshi Yonezawa, Yukihiko Kitamura, and Stephen J. Galli: Pillars Article: Fate of Bone Marrow-Derived Cultured Mast Cells After Intracutaneous, Intraperitoneal, And Intravenous Transfer Into Genetically Mast Cell-Deficient W/Wv Mice. Evidence That Cultured Mast Cells Can Give Rise To Both Connective Tissue Type And Mucosal Mast Cells. The Journal of Experimental Medicine. 1985. 162: 1025–1043
J Immunol 2009 183: 6863-6881 [PDF]

From Past Issues:

Andrew Getahun, Shannon K. O'Neill, and John C. Cambier: Establishing Anergy as a Bona Fide In Vivo Mechanism of B Cell Tolerance
J Immunol 2009 183: 5439-5441 [Full Text] [PDF] [Original Pillars Article]

Christopher C. Goodnow, Jeffrey Crosbie, Stephen Adelstein, Thomas B. Lavoie, Sandra J. Smith-Gill, Robert A. Brink, Helen Pritchard-Briscoe, John S. Wotherspoon, Robert H. Loblay, Kathy Raphael, Ronald J. Trent, and Antony Basten: Pillars Article: Altered Immunoglobulin Expression and Functional Silencing of Self-Reactive B Lymphocytes in Transgenic Mice. Nature 1988. 334: 676–682
J Immunol 2009 183: 5442-5448 [PDF]

Helene Bour-Jordan and Jeffery A. Bluestone: How Suppressor Cells Led to Anergy, Costimulation, and Beyond
J Immunol 2009 183: 4147-4149 [Full Text] [PDF] [Original Pillars Article]

Marc K. Jenkins and Ronald H. Schwartz: Pillars Article: Antigen Presentation by Chemically Modified Splenocytes Induces Antigen-Specific T Cell Unresponsiveness In Vitro and In Vivo. J. Exp. Med. 1987. 165: 302–319
J Immunol 2009 183: 4150-4167 [PDF]

Barrett J. Rollins: Where the Confusion Began: Cloning the First Chemokine Receptors
J Immunol 2009 183: 2893-2894 [Full Text] [PDF]

William E. Holmes, James Lee, Wun-Jing Kuang, Glenn C. Rice, and William I. Wood: Pillars Article: Structure and functional expression of a human interleukin-8 receptor. Science. 1991. 253: 1278–1280.
J Immunol 2009 183: 2895-2897 [PDF] [Original Pillars Article]

Phillip M. Murphy and H. Lee Tiffany: Pillars Article: Cloning of complementary DNA encoding a functional human interleukin-8 receptor. Science. 1991. 253: 1280–1283.
J Immunol 2009 183: 2898-2901 [PDF] [Original Pillars Article]

James Hagman: Conveying the Message: Identification of Ig- ${alpha}$ and Ig-β as Components of the B Cell Receptor Complex
J Immunol 2009 183: 1503-1504 [Full Text] [PDF] [Original Pillars Article]

Joachim Hombach, Takeshi Tsubata, Lise Leclercq, Heike Stappert, and Michael Reth: Pillars Article: Molecular components of the B-cell antigen receptor complex of the IgM class. 1990. Nature 243: 760–762
J Immunol 2009 183: 1505-1507 [PDF]

Juan Carlos Zuniga-Pflucker: The Original Intrathymic Progenitor from Which T Cells Originate
J Immunol 2009 183: 3-4 [Full Text] [PDF] [Original Pillars Article]

B. J. Fowlkes, Linette Edison, Bonnie J. Mathieson, and Thomas M. Chused: Pillars Article: Early T Lymphocytes. Differentiation In Vivo of Adult Intrathymic Precursor Cells. J. Exp. Med. 1985. 162: 802–822
J Immunol 2009 183: 5-25 [PDF]

Jack L. Strominger: Animal Antimicrobial Peptides: Ancient Players in Innate Immunity
J Immunol 2009 182: 6633-6634 [Full Text] [PDF] [Original Pillars Article]

Hakan Steiner, Dan Hultmark, Ake Engstrom, Hans Bennich, and Hans G. Boman: Pillars Article: Sequence and Specificity of Two Antibacterial Proteins Involved in Insect Immunity. Nature 1981. 292: 246–248
J Immunol 2009 182: 6635-6637 [PDF]

David L. Wiest: Identification of the Last Cog in a Ligand-Independent Signaling Machine?
J Immunol 2009 182: 5163-5164 [Full Text] [PDF] [Original Pillars Article]

Claude Saint-Ruf, Katharina Ungewiss, Marcus Groettrup, Ludovica Bruno, Hans Joerg Fehling, and Harald von Boehmer: Pillars Article: Analysis and Expression of a Cloned Pre-T Cell Receptor Gene. Science. 1994. 266: 1208–1212
J Immunol 2009 182: 5165-5169 [PDF]

Jay A. Levy: The Unexpected Pleiotropic Activities of RANTES
J Immunol 2009 182: 3945-3946 [Full Text] [PDF] [Original Pillars Article]

Thomas J. Schall, Jan Jongstra, Bradley J. Dyer, Jeffrey Jorgensen, Carol Clayberger, Mark M. Davis, and Alan M. Krensky: Pillars Article: A Human T Cell-Specific Molecule Is a Member of a New Gene Family. J. Immunol. 1988. 141: 1018–1025
J Immunol 2009 182: 3947-3954 [PDF]

Yuwen Zhu and Lieping Chen: Turning the Tide of Lymphocyte Costimulation
J Immunol 2009 182: 2557-2558 [Full Text] [PDF] [Original Pillars Article]

Peter S. Linsley, Edward A. Clark, and Jeffrey A. Ledbetter: Pillars Article: T-Cell Antigen CD28 Mediates Adhesion with B Cells by Interacting with Activation Antigen B7/BB-1. 1990. Proc. Natl. Acad. Sci. USA 87: 5031–5035
J Immunol 2009 182: 2559-2563 [PDF]

Christophe Viret and Werner Gurr: The Origin of the "One Cell-One Antibody" Rule
J Immunol 2009 182: 1229-1230 [Full Text] [PDF] [Original Pillars Article]

G. J. V. Nossal and Joshua Lederberg: Pillars Article: Antibody Production by Single Cells. 1958. Nature 181: 1419–1420.
J Immunol 2009 182: 1231-1232 [PDF]

Janet Stavnezer and Joonsoo Kang: The Surprising Discovery That TGFβ Specifically Induces the IgA Class Switch
J Immunol 2009 182: 5-7 [Full Text] [PDF]

Robert L. Coffman, Deborah A. Lebman, and Barbara Shrader: Pillars Article: Transforming Growth Factor β Specifically Enhances IgA Production by Lipopolysaccharide-Stimulated Murine B Lymphocytes. J. Exp. Med. 1989. 170: 1039–1044.
J Immunol 2009 182: 8-13 [PDF] [Original Pillars Article]

Eiichiro Sonoda, Ryoji Matsumoto, Yasumichi Hitoshi, Takehisa Ishii, Mineharu Sugimoto, Shukuro Araki, Akira Tominaga, Naoto Yamaguchi, and Kiyoshi Takatsu: Pillars Article: Transforming Growth Factor β Induces IgA Production and Acts Additively with Interleukin 5 for IgA Production. J. Exp. Med. 1989. 170: 1415–1420.
J Immunol 2009 182: 14-19 [PDF] [Original Pillars Article]

Graham Anderson and Eric J. Jenkinson: Bringing the Thymus to the Bench
J Immunol 2008 181: 7435-7436 [Full Text] [PDF] [Original Pillars Article]

J. H. Robinson and J. J. T. Owen: Pillars Article: Generation of T-cell Function in Organ Culture of Foetal Mouse Thymus. I. Mitogen Responsiveness
J Immunol 2008 181: 7437-7444 [PDF]

Leslie J. Berg: The "Bubble Boy" Paradox: An Answer That Led to a Question
J Immunol 2008 181: 5815-5816 [Full Text] [PDF] [Original Pillars Article]

Masayuki Noguchi, Huafang Yi, Howard M. Rosenblatt, Alexandra H. Filipovich, Stephen Adelstein, William S. Modi, O. Wesley McBride, and Warren J. Leonard: Pillars Article: Interleukin-2 Receptor ${gamma}$ Chain Mutation Results in X-Linked Severe Combined Immunodeficiency in Humans. Cell 73: 147–157.
J Immunol 2008 181: 5817-5827 [PDF]

William E. Paul: Th1 Fate Determination in CD4⁺ T Cells: Notice Is Served of the Importance of IL-12!
J Immunol 2008 181: 4435-4436 [Full Text] [PDF] [Original Pillars Article]

Chyi-Song Hsieh, Steven E. Macatonia, Catherine S. Tripp, Stanley F. Wolf, Anne O'Garra, and Kenneth M. Murphy: Pillars Article: Development of T_H1 CD4⁺ T Cells Through IL-12 Produced by Listeria-Induced Macrophages. 1993. Science 260(5107): 547–549
J Immunol 2008 181: 4437-4439 [PDF]

Melissa A. Brown: IL-4 Production by T Cells: You Need a Little to Get a Lot
J Immunol 2008 181: 2941-2942 [Full Text] [PDF] [Original Pillars Article]

Graham Le Gros, Shlomo Z. Ben-Sasson, Robert Seder, Fred D. Finkelman, and William E. Paul: Pillars Article: Generation of Interleukin 4 (IL-4)-producing Cells In Vivo and In Vitro: IL-2 and IL-4 Are Required For In Vitro Generation of IL-4-producing Cells. J. Exp. Med. 172: 921–929.
J Immunol 2008 181: 2943-2951 [PDF]

Harinder Singh: PU.1, a Shared Transcriptional Regulator of Innate and Adaptive Immune Cell Fates
J Immunol 2008 181: 1595-1596 [Full Text] [PDF] [Original Pillars Article]

Michael J. Klemsz, Scott R. McKercher, Antonio Celada, Charles Van Beveren, and Richard A. Maki: Pillars Article: The Macrophage and B Cell-Specific Transcription Factor PU.1 Is Related to the ets Oncogene. Cell, 1990. 61: 113–124.
J Immunol 2008 181: 1597-1608 [PDF]

Jan Vilcek: First Demonstration of the Role of TNF in the Pathogenesis of Disease
J Immunol 2008 181: 5-6 [Full Text] [PDF] [Original Pillars Article]

Bruce Beutler, Ian W. Milsark, and Anthony C. Cerami: Pillars Article: Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin. Science, 1985, 229(4716):869–871.
J Immunol 2008 181: 7-9 [PDF]

Leroy E. Hood: Wu and Kabat 1970: A Transforming View of Antibody Diversity
J Immunol 2008 180: 7055-7056 [Full Text] [PDF] [Original Pillars Article]

Tai Te Wu and Elvin A. Kabat: Pillars Article: An Analysis of the Sequences of the Variable Regions of Bence Jones Proteins and Myeloma Light Chains and their Implications for Antibody Complementarity. J. Exp. Med. 1970. 132: 211–250.
J Immunol 2008 180: 7057-7096 [PDF]

Marko Radic: Tracking and Trapping Somatic Mutations in Ig Genes
J Immunol 2008 180: 5763-5764 [Full Text] [PDF]

David McKean, Konrad Huppi, Michael Bell, Louis Staudt, Walter Gerhard, and Martin Weigert: Pillars Article: Generation of Antibody Diversity in the Immune Response of BALB/c Mice to Influenza Virus Hemagglutinin. Proc. Natl. Acad. Sci. USA 1984. 81: 3180–3184.
J Immunol 2008 180: 5765-5769 [PDF]

Pamela J. Fink: More Than Just Vanilla
J Immunol 2008 180: 4351-4352 [Full Text] [PDF] [Original Pillars Article]

Martin C. Raff: Pillars Article: Theta Isoantigen as a Marker of Thymus-Derived Lymphocytes in Mice. Nature 1969. 224: 378–379.
J Immunol 2008 180: 4353-4354 [PDF]

Luc Van Kaer: Antigen Presentation: Discovery of the Peptide TAP
J Immunol 2008 180: 2723-2724 [Full Text] [PDF]

John J. Monaco, Sungae Cho, and Michelle Attaya: Pillars Article: Transport Protein Genes in the Murine MHC: Possible Implications for Antigen Processing. Science 1990. 250: 1723–1726.
J Immunol 2008 180: 2725-2728 [PDF] [Original Pillars Article]

Edward V. Deverson, Irene R. Gow, W. John Coadwell, John J. Monaco, Geoffrey W. Butcher, and Jonathan C. Howard: Pillars Article: MHC Class II Region Encoding Proteins Related to the Multidrug Resistance Family of Transmembrane Transporters. Nature 1990. 348: 738–741.
J Immunol 2008 180: 2729-2732 [PDF] [Original Pillars Article]

John Trowsdale, Isabel Hanson, Ian Mockridge, Stephan Beck, Alain Townsend, and Adrian Kelly: Pillars Article: Sequences Encoded in the Class II Region of the MHC Related to the ’ABC’ Superfamily of Transporters. Nature 1990. 348: 741–744.
J Immunol 2008 180: 2733-2736 [PDF] [Original Pillars Article]

Thomas Spies, Maureen Bresnahan, Seiamak Bahram, Daniele Arnold, George Blanck, Elizabeth Mellins, Donald Pious, and Robert DeMars: Pillars Article: A Gene in the Human Major Histocompatibility Complex Class II Region Controlling the Class I Antigen Presentation Pathway. Nature 1990. 348: 744–747.
J Immunol 2008 180: 2737-2740 [PDF] [Original Pillars Article]

Jiri Mestecky and Charles O. Elson: Peyer’s Patches as the Inductive Site for IgA Responses
J Immunol 2008 180: 1293-1294 [Full Text] [PDF] [Original Pillars Article]

Susan W. Craig and John J. Cebra: Pillars Article: Peyer’s Patches: An Enriched Source of Precursors for IgA-Producing Immunocytes in the Rabbit. J. Exp. Med. 1971. 134: 188–200.
J Immunol 2008 180: 1295-1307 [PDF]

Vicky L. Brandt and David B. Roth: G.O.D.’s Holy Grail: Discovery of the RAG Proteins
J Immunol 2008 180: 3-4 [Full Text] [PDF] [Original Pillars Article]

David G. Schatz, Marjorie A. Oettinger, and David Baltimore: Pillars Article: The V(D)J Recombination Activating Gene, RAG-1. Cell 1989. 59: 1035–1048.
J Immunol 2008 180: 5-18 [PDF]

Hidde L. Ploegh: Bridging B Cell and T Cell Recognition of Antigen
J Immunol 2007 179: 7193-7193 [Full Text] [PDF]

Kenneth L. Rock, Baruj Benacerraf, and Abul K. Abbas: Pillars Article: Antigen Presentation by Hapten-Specific B Lymphocytes. 1. Role of Surface Immunoglobulin Receptors. J. Exp. Med. 1984. 160: 1102–1113.
J Immunol 2007 179: 7194-7205 [PDF] [Original Pillars Article]

Antonio Lanzavecchia: Pillars Article: Antigen-Specific Interaction between T and B Cells. Nature 1985. 314: 537–539.
J Immunol 2007 179: 7206-7208 [PDF] [Original Pillars Article]

Christopher C. Goodnow: Nossal and Pike 1975: A Turning Point in the Effort to Define Self-Tolerance Mechanisms
J Immunol 2007 179: 5617-5618 [Full Text] [PDF] [Original Pillars Article]

G. J. V. Nossal and Beverley L. Pike: Pillars Article: Evidence for the Clonal Abortion Theory of B-Lymphocyte Tolerance. J. Exp. Med. 1975. 141: 904–917.
J Immunol 2007 179: 5619-5632 [PDF]

Hidde L. Ploegh: The Peptide Cargo of Class I Molecules: Not Just Passive Passengers
J Immunol 2007 179: 4299-4300 [Full Text] [PDF] [Original Pillars Article]

Alain Townsend, Claes Ohlen, Judy Bastin, Hans-Gustaf Ljunggren, Linda Foster, and Klas Karre: Pillars Article: Association of Class I Major Histocompatibility Heavy and Light Chains Induced by Viral Peptides. Nature 1989. 340: 443–448.
J Immunol 2007 179: 4301-4306 [PDF]

Lawrence J. Stern: Characterizing MHC-Associated Peptides by Mass Spectrometry
J Immunol 2007 179: 2667-2668 [Full Text] [PDF] [Original Pillars Article]

Donald F. Hunt, Robert A. Henderson, Jeffrey Shabanowitz, Kazuyasu Sakaguchi, Hanspeter Michel, Noelle Sevilir, Andrea L. Cox, Ettore Appella, and Victor H. Engelhard: Pillars Article: Characterization of Peptides Bound to the Class I MHC Molecule HLA-A2.1 by Mass Spectrometry. Science 1992. 255: 1261–1263.
J Immunol 2007 179: 2669-2671 [PDF]

Joost J. Oppenheim: IL-2: More Than a T Cell Growth Factor
J Immunol 2007 179: 1413-1414 [Full Text] [PDF] [Original Pillars Article]

Francis W. Ruscetti, Doris A. Morgan, and Robert C. Gallo: Pillars Article: Functional and Morphologic Characterization of Human T Cells Continuously Grown In Vitro. J. Immunol. 1977. 119: 131–138.
J Immunol 2007 179: 1415-1422 [PDF]

Paul M. Allen: Making Antigen Presentable
J Immunol 2007 179: 3-4 [Full Text] [PDF] [Original Pillars Article]

Kirk Ziegler and Emil R. Unanue: Pillars Article: Identification of a Macrophage Antigen-Processing Event Required for I- Region-Restricted Antigen Presentation to T Lymphocytes. J. Immunol. 1981. 127: 1869–1875.
J Immunol 2007 179: 5-11 [PDF]

Jeremy M. Boss: Controlling the Ir Genes
J Immunol 2007 178: 6675-6676 [Full Text] [PDF] [Original Pillars Article]

Viktor Steimle, Luc A. Otten, Madeleine Zufferey, and Bernard Mach: Pillars Article: Complementation Cloning of an MHC Class II Transactivator Mutated in Hereditary MHC Class II Deficiency (or Bare Lymphocyte Syndrome). Cell 1993. 75: 135–146.
J Immunol 2007 178: 6677-6688 [PDF]

Theresa T. Pizarro and Fabio Cominelli: Cloning IL-1 and the Birth of a New Era in Cytokine Biology
J Immunol 2007 178: 5411-5412 [Full Text] [PDF] [Original Pillars Article]

Philip E. Auron, Andrew C. Webb, Lanny J. Rosenwasser, Steven F. Mucci, Alexander Rich, Sheldon M. Wolff, and Charles A. Dinarello: Nucleotide Sequence of Human Monocyte Interleukin 1 Precursor cDNA. Proc. Natl. Acad. Sci. USA 1984. 81: 7907–7911.
J Immunol 2007 178: 5413-5417 [PDF]

Jeffrey L. Platt: Allophenic Mice: A Pillar Awaiting Its Superstructure
J Immunol 2007 178: 4005-4006 [Full Text] [PDF] [Original Pillars Article]

Beatrice Mintz and Willys K. Silvers: Pillars Article: "Intrinsic" Immunological Tolerance in Allophenic Mice. Science 1967. 158: 1484–1487.
J Immunol 2007 178: 4007-4010 [PDF]

Olivera J. Finn: Human Tumor Immunology at the Molecular Divide
J Immunol 2007 178: 2615-2616 [Full Text] [PDF] [Original Pillars Article]

Pierre van der Bruggen, Catia Traversari, Patrick Chomez, Christophe Lurquin, Etienne De Plaen, Benoit J. Van den Eynde, Alexander Knuth, and Thierry Boon: Pillars Article: A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma. Science 1991. 254: 1643–1647.
J Immunol 2007 178: 2617-2621 [PDF]

Robert Winchester: A Golden Anniversary: Recognition That Rheumatoid Arthritis Sera Contain Autoantibodies Specific for Determinants on Native IgG Molecules
J Immunol 2007 178: 1227-1228 [Full Text] [PDF] [Original Pillars Article]

Edward C. Franklin, Halsted R. Holman, Hans J. Muller-Eberhard, and Henry G. Kunkel: Pillars Article: An Unusual Protein Component of High Molecular Weight in the Serum of Certain Patients with Rheumatoid Arthritis. J. Exp. Med. 1957. 105: 425–438.
J Immunol 2007 178: 1229-1242 [PDF]

Giorgio Trinchieri: The Birth of a Cell Type
J Immunol 2007 178: 3-4 [Full Text] [PDF] [Original Pillars Article]

Ralph M. Steinman and Zanvil A. Cohn: Pillars Article: Identification of a Novel Cell Type in Peripheral Lymphoid Organs of Mice. I. Morphology, Quantitation, Tissue Distribution. J. Exp. Med. 1973. 137: 1142–1162.
J Immunol 2007 178: 5-25 [PDF]

Michael J. May: A Nuclear Factor in B Cells and Beyond
J Immunol 2006 177: 7483-7484 [Full Text] [PDF] [Original Pillars Article]

Ranjan Sen and David Baltimore: Pillars Article: Multiple Nuclear Factors Interact with the Immunoglobulin Enhancer Sequences. Cell 1986. 46: 705–716.
J Immunol 2006 177: 7485-7496 [PDF]

Francisco Borrego: The First Molecular Basis of the "Missing Self" Hypothesis
J Immunol 2006 177: 5759-5760 [Full Text] [PDF] [Original Pillars Article]

Franz M. Karlhofer, Randall K. Ribaudo, and Wayne M. Yokoyama: Pillars Article: MHC Class I Alloantigen Specificity of Ly-49⁺ IL-2-Activated Natural Killer Cells. Nature 1992. 358: 66–70.
J Immunol 2006 177: 5761-5765 [PDF]

Patricia J. Gearhart: Antibody Wars: Extreme Diversity
J Immunol 2006 177: 4235-4236 [Full Text] [PDF] [Original Pillars Article]

Sydney Brenner and Cesar Milstein: Pillars Article: Origin of Antibody Variation. Nature 1966. 211: 242–243.
J Immunol 2006 177: 4237-4238 [PDF]

Linda A. Sherman: To Each (MHC Molecule) Its Own (Binding Motif)
J Immunol 2006 177: 2739-2740 [Full Text] [PDF] [Original Pillars Article]

Kirsten Falk, Olaf Rotzschke, Stefan Stevanovic, Gunther Jung, and Hans-Georg Rammensee: Pillars Article: Allele-Specific Motifs Revealed by Sequencing of Self-Peptides Eluted from MHC Molecules. Nature 1991. 351: 290–296.
J Immunol 2006 177: 2741-2747 [PDF]

Pamela J. Fink: T Cells Stop to Smell the (Antigenic) Roses
J Immunol 2006 177: 1379-1380 [Full Text] [PDF] [Original Pillars Article]

Jonathan Sprent, Jacques F. A. P. Miller, and Graham F. Mitchell: Pillars Article: Antigen-Induced Selective Recruitment of Circulating Lymphocytes. Cell. Immunol. 1971. 2: 171–181.
J Immunol 2006 177: 1381-1391 [PDF]

Steven D. Rosen: Homing in on L-Selectin
J Immunol 2006 177: 3-4 [Full Text] [PDF] [Original Pillars Article]

W. Michael Gallatin, Irving L. Weissman, and Eugene C. Butcher: Pillars Article: A Cell-Surface Molecule Involved in Organ-Specific Homing of Lymphocytes. Nature 1983. 304: 30–34.
J Immunol 2006 177: 5-9 [PDF]

Carol F. Webb and Paul W. Kincade: The Divergence of Lymphocyte Development Pathways
J Immunol 2006 176: 6369-6369 [Full Text] [PDF] [Original Pillars Article]

Max D. Cooper, Raymond D. A. Peterson, Mary Ann South, and Robert A. Good: Pillars Article: The Functions of the Thymus System and the Bursa System in the Chicken. J. Exp. Med. 1966. 123: 75–102.
J Immunol 2006 176: 6370-6404 [PDF]

Yvonne Paterson: When It Comes to CTL Recognition, Size Does Matter
J Immunol 2006 176: 5139-5140 [Full Text] [PDF] [Original Pillars Article]

A. R. M. Townsend, J. Rothbard, F. M. Gotch, G. Bahadur, D. Wraith, and A. J. McMichael: Pillars Article: The Epitopes of Influenza Nucleoprotein Recognized by Cytotoxic T Lymphocytes Can Be Defined with Short Synthetic Peptides. 1986. Cell 44: 959–968.
J Immunol 2006 176: 5141-5150 [PDF]

Leonard Chess: The Birth of Functionally Distinct T Cell Subsets
J Immunol 2006 176: 3859-3860 [Full Text] [PDF] [Original Pillars Article]

H. Cantor and E. A. Boyse: Pillars Article: Functional Subclasses of T Lymphocytes Bearing Different Ly Antigens. I. The Generation of Functionally Distinct T-Cell Subclasses is a Differentiative Process Independent of Antigen. J. Exp. Med. 1975. 141: 1376–1389.
J Immunol 2006 176: 3861-3874 [PDF]

Stephen M. Hedrick: The TCR of Mice and Men
J Immunol 2006 176: 2681-2682 [Full Text] [PDF] [Original Pillars Article]

John Kappler, Ralph Kubo, Kathryn Haskins, Charles Hannum, Philippa Marrack, Michele Pigeon, Bradley McIntyre, James Allison, and Ian Trowbridge: Pillars Article: The Major Histocompatibility Complex-restricted Antigen Receptor on T Cells in Mouse and Man: Identification of Constant and Variable Peptides. Cell 1983; 35: 295–302.
J Immunol 2006 176: 2683-2690 [PDF]

George C. Tsokos: In the Beginning Was Sm
J Immunol 2006 176: 1295-1296 [Full Text] [PDF] [Original Pillars Article]

E. M. Tan and H. G. Kunkel: Pillars Article: Characteristics of a Soluble Nuclear Antigen Precipitating with Sera of Patients with Systemic Lupus Erythematosus. J. Immunol. 1966. 96: 464–471.
J Immunol 2006 176: 1297-1304 [PDF]

Harald von Boehmer: Shaping the T Cell Repertoire
J Immunol 2006 176: 3-4 [Full Text] [PDF] [Original Pillars Article]

Michael J. Bevan: Pillars Article: In a Radiation Chimaera, Host H-2 Antigens Determine Immune Responsiveness of Donor Cytotoxic Cells. Nature 1977. 269: 417–418.
J Immunol 2006 176: 5-6 [PDF]

Harald von Boehmer: Shaping the T Cell Repertoire
J Immunol 2005 175: 7067-7068 [Full Text] [PDF] [Original Pillars Article]

Michael John Bevan: Pillars Article: The Major Histocompatibility Complex Determines Susceptibility to Cytotoxic T Cells Directed against Minor Histocompatibility Antigens. J. Exp. Med. 1975. 142: 1349–1364.
J Immunol 2005 175: 7069-7084 [PDF]

Richard M. Ransohoff: Selective Leukocyte Chemoattractants Emerge from the Primeval Sup(ernatants)
J Immunol 2005 175: 5567-5568 [Full Text] [PDF] [Original Pillars Article]

Teizo Yoshimura, Kouji Matsushima, Joost J. Oppenheim, and Edward J. Leonard: Pillars Article: Neutrophil Chemotactic Factor Produced by Lipopolysaccharide (LPS)-Stimulated Human Blood Mononuclear Leukocytes: Partial Characterization and Separation from Interleukin 1 (IL 1). J. Immunol., 1987, 139: 788–793.
J Immunol 2005 175: 5569-5574 [PDF]

Janice S. Blum: One for One Peptide Binding to MHC Molecules
J Immunol 2005 175: 4161-4162 [Full Text] [PDF] [Original Pillars Article]

Bruce P. Babbitt, Paul M. Allen, Gary Matsueda, Edgar Haber, and Emil R. Unanue: Pillars Article: Binding of Immunogenic Peptides to Ia Histocompatibility Molecules. Nature. 1985. 317: 359–361.
J Immunol 2005 175: 4163-4165 [PDF]

Arthur Weiss: Discovering the TCR $beta$ -Chain by Subtraction
J Immunol 2005 175: 2769-2770 [Full Text] [PDF] [Original Pillars Article]

Stephen M. Hedrick, David I. Cohen, Ellen A. Nielsen, and Mark M. Davis: Pillars Article: Isolation of cDNA Clones Encoding T Cell-Specific Membrane-Associated Proteins. Nature, 1984, 308: 149–153.
J Immunol 2005 175: 2771-2775 [PDF]

Jerry R. McGhee: Peyer’s Patch Germinal Centers: The Elusive Switch Site for IgA
J Immunol 2005 175: 1361-1362 [Full Text] [PDF] [Original Pillars Article]

Eugene C. Butcher, Robert V. Rouse, Robert L. Coffman, Carol N. Nottenburg, Richard R. Hardy, and Irving L. Weissman: Pillars Article: Surface Phenotype of Peyer’s Patch Germinal Center Cells: Implications for the Role of Germinal Centers in B Cell Differentiation. J. Immunol. 1982. 129: 2698–2707.
J Immunol 2005 175: 1363-1372 [PDF]

Jerry R. McGhee: The World of Th1/Th2 Subsets: First Proof
J Immunol 2005 175: 3-4 [Full Text] [PDF] [Original Pillars Article]

Timothy R. Mosmann, Holly Cherwinski, Martha W. Bond, Martin A. Giedlin, and Robert L. Coffman: Pillars Article: Two Types of Murine Helper T Cell Clone. I. Definition According to Profiles of Lymphokine Activities and Secreted Proteins. J. Immunol., 1986, 136: 2348–2357.
J Immunol 2005 175: 5-14 [PDF]

Lewis L. Lanier: Missing Self, NK Cells, and The White Album
J Immunol 2005 174: 6565-6565 [Full Text] [PDF] [Original Pillars Article]

Klas Karre, Hans Gustaf Ljunggren, Gerald Piontek, and Rolf Kiessling: Pillars Article: Selective Rejection of H–2-Deficient Lymphoma Variants Suggests Alternative Immune Defence Strategy. Nature, 1986, 391: 675–678
J Immunol 2005 174: 6566-6569 [PDF]

Michael P. Cancro: Crossing the Threshold of Lymphocyte Activation
J Immunol 2005 174: 5159-5160 [Full Text] [PDF] [Original Pillars Article]

Norman R. Klinman: Pillars Article: The Mechanism of Antigenic Stimulation of Primary and Secondary Clonal Precursor Cells. J. Exp. Med., 1972, 136: 241–260
J Immunol 2005 174: 5161-5180 [PDF]

Jonathan Sprent: Proving Negative Selection in the Thymus
J Immunol 2005 174: 3841-3842 [Full Text] [PDF] [Original Pillars Article]

John W. Kappler, Neal Roehm, and Philippa Marrack: Pillars Article: T Cell Tolerance by Clonal Elimination in the Thymus Cell, 1987, 49: 273–280.
J Immunol 2005 174: 3843-3850 [PDF]

David H. Margulies: Monoclonal Antibodies: Producing Magic Bullets by Somatic Cell Hybridization
J Immunol 2005 174: 2451-2452 [Full Text] [PDF] [Original Pillars Article]

G. Kohler and C. Milstein: Pillars Article: Continuous cultures of fused cells secreting antibody of predefined specificity. Nature, 1975, 256 (5517): 495–497.
J Immunol 2005 174: 2453-2455 [PDF]

Lewis L. Lanier: First Sighting of the Elusive T Cell Antigen Receptor
J Immunol 2005 174: 1143-1143 [Full Text] [PDF] [Original Pillars Article]

James P. Allison, Bradley W. McIntyre, and David Bloch: Pillars Article: Tumor-specific antigen of murine T-lymphoma defined with monoclonal antibody. 1982, J. Immunol. 129: 2293–2300.
J Immunol 2005 174: 1144-1151 [PDF]

Peter Parham: Putting a Face to MHC Restriction
J Immunol 2005 174: 3-5 [Full Text] [PDF]

P. J. Bjorkman, M. A. Saper, B. Samraoui, W. S. Bennett, J. L. Strominger, and D. C. Wiley: Pillars Article: Structure of the human class I histocompatibility antigen, HLA-A2.
J Immunol 2005 174: 6-12 [PDF] [Original Pillars Article]

P. J. Bjorkman, M. A. Saper, B. Samraoui, W. S. Bennett, J. L. Strominger, and D. C. Wiley: Pillars Article: The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens.
J Immunol 2005 174: 13-19 [PDF] [Original Pillars Article]

J. Donald Capra: Multiple Genes, One Polypeptide Chain
J Immunol 2004 173: 6501-6502 [Full Text] [PDF] [Original Pillars Article]

P. Early, H. Huang, M. Davis, K. Calame, and L. Hood: Pillars Article: An Immunoglobulin Heavy Chain Variable Region Gene Is Generated from Three Segments of DNA: V_H, D and J_H. Cell, 1980, 19: 981–992.
J Immunol 2004 173: 6503-6514 [PDF]

Norman R. Klinman: When Two-Dimensional Structure Led the Way
J Immunol 2004 173: 5333-5334 [Full Text] [PDF] [Original Pillars Article]

Gerald M. Edelman, Bruce A. Cunningham, W. Einar Gall, Paul D. Gottlieb, Urs Rutishauser, and Myron J. Waxdal: Pillars Article: The Covalent Structure of an Entire ${gamma}$ G Immunoglobulin Molecule. Proc. Natl. Acad. Sci. USA, 1969, 63: 78–85.
J Immunol 2004 173: 5335-5342 [PDF]

Patricia J. Gearhart: The Birth of Molecular Immunology
J Immunol 2004 173: 4259-4259 [Full Text] [PDF] [Original Pillars Article]

N. Hozumi and S. Tonegawa: Pillars Article: Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions
J Immunol 2004 173: 4260-4264 [PDF]

Michael J. Bevan: Altered Self, Altered World
J Immunol 2004 173: 2897-2898 [Full Text] [PDF] [Original Pillars Article]

Rolf M. Zinkernagel and Peter C. Doherty: Pillars Article: Immunological Surveillance against Altered Self Components by Sensitised T Lymphocytes in Lymphocytic Choriomeningitis. Nature, 1974, 251: 547–548.
J Immunol 2004 173: 2899-2900 [PDF]

Jack R. Bennink: Making the Connection: Antibody Responsiveness and MHC Genes
J Immunol 2004 173: 1499-1499 [Full Text] [PDF] [Original Pillars Article]

Hugh O. McDevitt and Allen Chinitz: Pillars Article: Genetic Control of the Antibody Responses: Relationship between Immune Response and Histocompatibility (H-2) Type. Science, 1969, 163:1207–1208
J Immunol 2004 173: 1500-1501 [PDF]

Jonathan S. Bromberg: The Beginnings of T-B Collaboration
J Immunol 2004 173: 7-13 [Full Text] [PDF] [Original Pillars Article]